Gene

KWMTBOMO03081  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA005816

Annotation

PREDICTED:_mitochondrial_intermediate_peptidase_isoform_X2_[Bombyx_mori]

Location

Bomo_Chr5(-):17653825-17663963      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 1.331 Mitochondrial   Reliability : 1.743 Nuclear   Reliability : 1.043

CDS

ATGTCTACAATGAAGTTATTGAAACCCCTCTGGATCCTCCGAAATGGCAGAAAGAAGAAATTGGGATGCTCTGTCAGTACTTGGTCACCTTTGGCAACAGCATTCAACACCAGACCAAATTCCAGACCTATTTTTGACTCTTTAAAGGAAAGAACTGGCCTCTTCAATAAACCAGAGCTCACAACTTTTGAAGGCTTCTACACGCTCAAGGACCAGGCTATCGAAGCAACTGATCGTCTGATAGAAGAGGCCACCAACAGCCCCACGCGTCCTATGGTCGAGATATTTGATGAGCTTTCCGACACACTGTGCAAAGTTGCAGATCTTGCTGAGTTTGTGAGGATAGCTCACCCCCAACCACATTTCGCACGAGCTGCTGAAGAAGCCTGTATCAGCATTAGTGGAGTTGTCGAAAAGTTAAACACGCACAAAGGCTTGTACGAAGCTTTAAAGAAGTCAGTTGAGAATGGAACATCTGGAGACAAACATTTAGCAGAATTATTCTTGTTCGACTTTGAACAGAGCGGAATACACCTCGAAGAGAACAAAAGGAAGAGTGTGGTGGCTCTCAATGATGTTATCCTCCAAACTGGGCAGAGGTTCATGGCCGGAGCTGCTAAACCAAGACGTGTTTCTCGAAGTGCTGTACCTCAGAATGTTAGACATTTCTTCAGCACCGAAGGTGACAATATAATAGTGAGCGGGGTGTACGCGGAGTGCGGGGAGGCGGCCGCCCGCGAGGCTGCCTACCGACTGTACCTAGCGCCGGACGGCACGCAGGACCGCCTGCTGGACGCCGTGCTGCAGGCCAGGCACCACATGGCCACGCTCTGCGGCTTCCAGACCTACGCCGACAGAGCAATAAAAGCGAGTACAATGGAGACAGCAGCAAACGTGCGGCAGTTTCTCGACCTCCTCTCTGACGGCCTCCACGACCGCGCTAGAATGGACTTCGACGTGATGCTGAAGATGAAGAAACAGGAAACGCCATATCTGGACCAATTAAACTGCTGGGACACGCCGTACTATACTCACAAGGCGAAGAACTTGTTATTGGACCAGGCCAATTCGGACTTCAGTCCGTACTTCAGTCTGGGCGCGTGCATGGAGGGCTTGGATATGTTGTGTCAAGAGCTATACGGCATCAGTCTGAAGTCCGAGGAAATGTTGCCAGGCGAGTCGTGGTCTCCGGACGTATACAAGCTGGCCGTGGTCCACGAGTCGGAGGGGCTGCTGGGCCACATCTACTGCGACCTGTACGAGCGGCCCGGGAAGCCGCATCAGGACTGCCACTTCACTATACAGGGCGGGAAGCTGTTACCAGATGGCTCCTACCAGAACCCGATCGTGGTGATAATGTTGTCGCTGAGCGGCGGGCACCGCTCGGGGCCGGCGCTGCTGTCCGCGGGCGCGCTGGACAACCTGTTCCACGAGGCGGGCCACGCGCTGCACTCCATGCTGGGCCGCGCGCCCCACCAGCACGTGGCCGGCACGCGCTGCCCCACCGACCTGGCCGAGCTGCCCAGCGTGCTCATGGAGTGCTTCGCGGCCGACCCGCAGGTGCTGCGCAGGTTCGCGCGGCACTTCCAGACGCGGCAGGCGGCGCCGGAGCGCACGCTGCAGCGCCTGTGCGCCTCCAAGCGACTGTTCGCCGCCAGCGAGATGCAGCTGCAGGTGTTTTATTCAGCCCTGGACCAGCAGTACCACGACCGGCCCGCAGCGCCCGGGGGCCGCACCACGGACGATCTGAAAGAAGTCCAGAAACAATATTATGGACTTCCGTATGTCGAAAACACAGCGTGGCAGCACCGGTTCAGCCACCTGGTCGGCTACGGCGCCAAGTACTACTCCTACCTCATCTCGCGCGCGCTCGCCTCCTCCGCCTGGAACACGCACTTCGCGGCCGACCCGCTCGCGCGCCGCGCCGGCCGCCGCCTGCGGGACCGCGTGCTGCGACACGGGGGCGCCGTGCCGCCGCAGGTCCTGCTCAAGGACTACCTGGAAATGGAGATAACTCCACAGACGCTCGCGTCGGCGCTGATAGACGAGCTGGACTGCCACAAGGACCACCTCGACACCGTGCTAAAGATACTGGACAGAAAGTAA

Protein

MSTMKLLKPLWILRNGRKKKLGCSVSTWSPLATAFNTRPNSRPIFDSLKERTGLFNKPELTTFEGFYTLKDQAIEATDRLIEEATNSPTRPMVEIFDELSDTLCKVADLAEFVRIAHPQPHFARAAEEACISISGVVEKLNTHKGLYEALKKSVENGTSGDKHLAELFLFDFEQSGIHLEENKRKSVVALNDVILQTGQRFMAGAAKPRRVSRSAVPQNVRHFFSTEGDNIIVSGVYAECGEAAAREAAYRLYLAPDGTQDRLLDAVLQARHHMATLCGFQTYADRAIKASTMETAANVRQFLDLLSDGLHDRARMDFDVMLKMKKQETPYLDQLNCWDTPYYTHKAKNLLLDQANSDFSPYFSLGACMEGLDMLCQELYGISLKSEEMLPGESWSPDVYKLAVVHESEGLLGHIYCDLYERPGKPHQDCHFTIQGGKLLPDGSYQNPIVVIMLSLSGGHRSGPALLSAGALDNLFHEAGHALHSMLGRAPHQHVAGTRCPTDLAELPSVLMECFAADPQVLRRFARHFQTRQAAPERTLQRLCASKRLFAASEMQLQVFYSALDQQYHDRPAAPGGRTTDDLKEVQKQYYGLPYVENTAWQHRFSHLVGYGAKYYSYLISRALASSAWNTHFAADPLARRAGRRLRDRVLRHGGAVPPQVLLKDYLEMEITPQTLASALIDELDCHKDHLDTVLKILDRK

Cofactor

Zn(2+)

Similarity

Belongs to the peptidase M3 family.

Uniprot

H9J8H4   A0A194PQV3   A0A2H1V1U6   A0A2A4K8W3   A0A212EKU1   A0A1S4F4W5   + More
Q17F93   A0A084VF33   A0A182J0C4   B0WT45   A0A1Q3F2A6   A0A182QJR8   A0A2M4AJY9   W5JFN9   A0A182FFY8   A0A2M4BFQ7   A0A2M4BFZ3   A0A2M4BFP4   A0A182SPU2   A0A2J7QC24   A0A182WIK2   Q7QJY5   A0A1B0ESP3   A0A182XZI8   A0A182JT41   A0A182R4R0   A0A1L8E140   A0A1L8E193   A0A1L8E1N0   A0A182LRM5   A0A067RKH4   Q28YP7   A0A182U055   A0A1B6C972   A0A1B6HVG2   A0A182LGT9   A0A182I3Y3   B4H8C5   A0A1B6HIE8   A0A3B0JQ62   A0A182USY3   W8BQ27   B4NMV8   A0A0L0BTW9   A0A0K8W4F5   A0A1L8E0X4   A0A0K8UCU5   A0A034WF14   A0A1I8MYY9   T1P7J4   A0A0M4ECE2   A0A1W4VYC8   A0A0M4EEH6   B4J5Q8   B4LNM6   B3MBQ0   B4KM63   A0A2J7QC18   A0A0J9R6B8   B4II08   A0A195FNY2   B4QCP2   A0A1J1I5C7   A0A1I8PML9   A1Z6H6   Q8T8Q1   B3N3I6   A0A2J7QC34   A0A195DWF9   A0A3B0JKC6   A0A151XD88   A0A151IDL4   A0A195B6M0   B4NYX7   A0A2M3ZAS8   A0A1A9XVG3   A0A1A9ZYC7   A0A0A9WMI4   A0A1B0G3G5   F4X128   A0A1B0AXD2   A0A023F246   A0A336JW82   A0A1A9WMX6   U4UE67   A0A3L8DRL2   N6TZD0   E9J3A6   A0A069DWS0   K7J8I2   E2BWA5   A0A232FCB9   A0A1A9V2E5   A0A026WZ09   A0A0P4VQH3   T1HRH4   A0A182XRT2   A0A1L8E109   A0A0V0GCF7  

Pubmed

19121390    26354079    22118469    17510324    24438588    20920257    + More
23761445    12364791    14747013    17210077    25244985    24845553    15632085    17994087    20966253    24495485    26108605    25348373    25315136    22936249    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    17550304    25401762    21719571    25474469    23537049    30249741    21282665    26334808    20075255    20798317    28648823    24508170    27129103   

EMBL

BABH01027415    BABH01027416    KQ459597    KPI95124.1    ODYU01000109    SOQ34322.1    + More
NWSH01000041    PCG80344.1    AGBW02014213    OWR42103.1    CH477272    EAT45254.1    ATLV01012360    KE524785    KFB36577.1    DS232080    EDS34188.1    GFDL01013350    JAV21695.1    AXCN02000894    GGFK01007778    MBW41099.1    ADMH02001644    ETN61629.1    GGFJ01002731    MBW51872.1    GGFJ01002730    MBW51871.1    GGFJ01002729    MBW51870.1    NEVH01016292    PNF26131.1    AAAB01008807    EAA04703.3    AJWK01004522    GFDF01001667    JAV12417.1    GFDF01001668    JAV12416.1    GFDF01001669    JAV12415.1    AXCM01005238    AXCM01005239    AXCM01005240    KK852415    KDR24371.1    CM000071    EAL25918.2    GEDC01027252    JAS10046.1    GECU01029045    JAS78661.1    APCN01000228    CH479223    EDW34960.1    GECU01033223    JAS74483.1    OUUW01000001    SPP75809.1    GAMC01005448    JAC01108.1    CH964282    EDW85697.1    JRES01001351    KNC23456.1    GDHF01022435    GDHF01006328    JAI29879.1    JAI45986.1    GFDF01001691    JAV12393.1    GDHF01027921    JAI24393.1    GAKP01006579    JAC52373.1    KA644442    AFP59071.1    CP012524    ALC41377.1    ALC40435.1    CH916367    EDW01834.1    CH940648    EDW62206.1    CH902619    EDV38196.1    CH933808    EDW08727.2    PNF26136.1    CM002911    KMY91653.1    CH480841    EDW49534.1    KQ981387    KYN42022.1    CM000362    EDX05831.1    CVRI01000042    CRK95543.1    AE013599    AAF57312.1    AY075581    AAL68386.1    CH954177    EDV59868.1    PNF26132.1    KQ980204    KYN17245.1    SPP75810.1    KQ982294    KYQ58290.1    KQ977985    KYM98339.1    KQ976574    KYM80151.1    CM000157    EDW89828.1    GGFM01004895    MBW25646.1    GBHO01033947    GBRD01013110    JAG09657.1    JAG52716.1    CCAG010013345    GL888525    EGI59839.1    JXJN01005228    GBBI01003294    JAC15418.1    UFQS01000006    UFQT01000006    SSW97016.1    SSX17403.1    KB632254    ERL90623.1    QOIP01000005    RLU23085.1    APGK01055188    KB741261    ENN71597.1    GL768061    EFZ12674.1    GBGD01000737    JAC88152.1    GL451103    EFN80009.1    NNAY01000478    OXU28113.1    KK107063    EZA60986.1    GDKW01001885    JAI54710.1    ACPB03004826    GFDF01001697    JAV12387.1    GECL01001053    JAP05071.1   

Proteomes

UP000005204    UP000053268    UP000218220    UP000007151    UP000008820    UP000030765    + More
UP000075880    UP000002320    UP000075886    UP000000673    UP000069272    UP000075901    UP000235965    UP000075920    UP000007062    UP000092461    UP000076408    UP000075881    UP000075900    UP000075883    UP000027135    UP000001819    UP000075902    UP000075882    UP000075840    UP000008744    UP000268350    UP000075903    UP000007798    UP000037069    UP000095301    UP000092553    UP000192221    UP000001070    UP000008792    UP000007801    UP000009192    UP000001292    UP000078541    UP000000304    UP000183832    UP000095300    UP000000803    UP000008711    UP000078492    UP000075809    UP000078542    UP000078540    UP000002282    UP000092443    UP000092445    UP000092444    UP000007755    UP000092460    UP000091820    UP000030742    UP000279307    UP000019118    UP000002358    UP000008237    UP000215335    UP000078200    UP000053097    UP000015103    UP000076407   

PRIDE

H9J8H4    A1Z6H6    Q8T8Q1   

Pfam

PF01432   Peptidase_M3        + More
PF00028   Cadherin
PF00400   WD40

Interpro

IPR001567   Pept_M3A_M3B        + More
IPR024077   Neurolysin/TOP_dom2       
IPR033851   M3A_MIP       
IPR024079   MetalloPept_cat_dom_sf       
IPR015919   Cadherin-like_sf       
IPR002126   Cadherin-like_dom       
IPR019775   WD40_repeat_CS       
IPR036322   WD40_repeat_dom_sf       
IPR017986   WD40_repeat_dom       
IPR037289   Elp2       
IPR001680   WD40_repeat       
IPR015943   WD40/YVTN_repeat-like_dom_sf       
IPR006594   LisH       
IPR011989   ARM-like       
IPR016024   ARM-type_fold       

SUPFAM

SSF49313   SSF49313        + More
SSF50978   SSF50978       
SSF48371   SSF48371       

Gene 3D

1.10.1370.10     3.40.390.10     2.130.10.10     1.25.10.10    

CDD

cd06457  M3A_MIP

ProteinModelPortal

H9J8H4   A0A194PQV3   A0A2H1V1U6   A0A2A4K8W3   A0A212EKU1   A0A1S4F4W5   + More
Q17F93   A0A084VF33   A0A182J0C4   B0WT45   A0A1Q3F2A6   A0A182QJR8   A0A2M4AJY9   W5JFN9   A0A182FFY8   A0A2M4BFQ7   A0A2M4BFZ3   A0A2M4BFP4   A0A182SPU2   A0A2J7QC24   A0A182WIK2   Q7QJY5   A0A1B0ESP3   A0A182XZI8   A0A182JT41   A0A182R4R0   A0A1L8E140   A0A1L8E193   A0A1L8E1N0   A0A182LRM5   A0A067RKH4   Q28YP7   A0A182U055   A0A1B6C972   A0A1B6HVG2   A0A182LGT9   A0A182I3Y3   B4H8C5   A0A1B6HIE8   A0A3B0JQ62   A0A182USY3   W8BQ27   B4NMV8   A0A0L0BTW9   A0A0K8W4F5   A0A1L8E0X4   A0A0K8UCU5   A0A034WF14   A0A1I8MYY9   T1P7J4   A0A0M4ECE2   A0A1W4VYC8   A0A0M4EEH6   B4J5Q8   B4LNM6   B3MBQ0   B4KM63   A0A2J7QC18   A0A0J9R6B8   B4II08   A0A195FNY2   B4QCP2   A0A1J1I5C7   A0A1I8PML9   A1Z6H6   Q8T8Q1   B3N3I6   A0A2J7QC34   A0A195DWF9   A0A3B0JKC6   A0A151XD88   A0A151IDL4   A0A195B6M0   B4NYX7   A0A2M3ZAS8   A0A1A9XVG3   A0A1A9ZYC7   A0A0A9WMI4   A0A1B0G3G5   F4X128   A0A1B0AXD2   A0A023F246   A0A336JW82   A0A1A9WMX6   U4UE67   A0A3L8DRL2   N6TZD0   E9J3A6   A0A069DWS0   K7J8I2   E2BWA5   A0A232FCB9   A0A1A9V2E5   A0A026WZ09   A0A0P4VQH3   T1HRH4   A0A182XRT2   A0A1L8E109   A0A0V0GCF7  

PDB

2O36     E-value=3.61546e-36,     Score=382

KEGG

101741797    K01410 mitochondrial intermediate peptidase [EC:3.4.24.59] | (RefSeq) mitochondrial intermediate pep

GO

GO:0006627   GO:0004222   GO:0005759   GO:0046872   GO:0006508   GO:0005739   GO:0006518   GO:0016020   GO:0007156   GO:0005509   GO:0033588   GO:0002098   GO:0016485   GO:0008237   GO:0051103   GO:0003677   GO:0006281   GO:0048384  

PANTHER

PTHR44111  

Length:

701

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.03442

Exp number, first 60 AAs:

0.0265

Total prob of N-in:

0.00159

outside

1  -  701

 

 

Pi

251.416502

Theta

170.165751

Tajima's D

1.762067

CLR

0.005793

CSRT

0.84030798460077

Interpretation

Uncertain