Gene

KWMTBOMO03045  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA005826

Annotation

PREDICTED:_15-hydroxyprostaglandin_dehydrogenase_[NAD(+)]-like?_partial_[Bombyx_mori]

Location

Bomo_Chr5(-):16443132-16444597      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 1.333 Mitochondrial   Reliability : 1.016 PlasmaMembrane   Reliability : 1.005

CDS

ATGAAATTACTTCTATTCCTGGTACTCGCCATCTCTGCATACCAGTGTTTTGGCTACCCAAAAAAACCAATAGATTCTCAATACGAAGTGAAAAACAAAGTAATTATTGTTACTGGAGCTGCTCGAGGTATTGGTTATGCAATAGCCGATAATTTTCTCGAAAAGGGAGCAAAGATCATAATCATACTAGACATCGATGTGCCCAAAGGACGAGACGCCGCGGCAACTTTAAATACAAAATACGGAAAGAACAGCGCGGTTTTCATCAAGTGTGACGTCACGAAAGATCTAGATGAAGTCTCCCAACTAATCCTAAGAAACTACGACGTAGATATTTTGGTAAATTGCGCAGGAGTGGTCAACGAATTTGATCCTAGAAAGACGTTGACGACAAACTCAATAGCTCTTATCGAATGGTCCCTTAAGTTCAGAGAGTACATGAGAAAAGACAATGGTGGAAAAGGCGGAACGATTATCAACATTTCTTCTATATACGGGTACACAATAGACCCGTTCTTGGTTTCGTATAAGGCGTCAAAGTTTGCTGTCTTAGGGTTTTCCAAATCACTGGGTCATGAATTGAACTACAAGATTACTGGAGTCAGGGTGCTCGTTATATGTCCCGGTGCTACAGATACAAGATTGGCAAAGAACGTTAAGGTATTCCCCGAACACAACGAGCTCTTCACAAGGCTCACAGACAAAGCACAAAAGCAGAGTGCAGATGCCGTTGGTAGGGGAGTCGTGCAAGTTTACAAGTCAGCTAGAACAGGTACGGCTTGGGACATTATTGGGGGGACACCCCCTGTTGAATCGCCTCTTGCAGCATACACTTCCATGAAAGAAATCTTGGAAAGTTAA

Protein

MKLLLFLVLAISAYQCFGYPKKPIDSQYEVKNKVIIVTGAARGIGYAIADNFLEKGAKIIIILDIDVPKGRDAAATLNTKYGKNSAVFIKCDVTKDLDEVSQLILRNYDVDILVNCAGVVNEFDPRKTLTTNSIALIEWSLKFREYMRKDNGGKGGTIINISSIYGYTIDPFLVSYKASKFAVLGFSKSLGHELNYKITGVRVLVICPGATDTRLAKNVKVFPEHNELFTRLTDKAQKQSADAVGRGVVQVYKSARTGTAWDIIGGTPPVESPLAAYTSMKEILES

Similarity

Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Uniprot

H9J8I4   H9J8I5   Q1HPX6   H9J8J0   H9J8I9   A0A2H1VNC8   + More
H9J369   A0A1L8D6N5   A0A194R949   A0A2W1BR60   A0A0H4TDA9   A0A0F6Q0W0   A0A194R584   A0A212F911   A0A0L7KQW0   A0A0L7LJP6   A0A0F6Q0X5   A0A2A4JIR0   H9JWW1   H9JWW0   A0A2W1BL60   A0A0F6Q2J9   A0A2W1BSK9   H9JYK0   A0A0H4TD16   H9JWW7   D2SNK3   H9J8I6   A0A194QJQ6   A0A194R3L5   A0A212F936   I4DKW3   A0A194R4F0   S4PIB4   U5KC20   A0A0H4TH26   H9JWW6   A0A2H1VSR5   A0A0F6Q4H7   A0A2H1VR53   H9J354   H9J355   A0A0L7K2F9   A0A2A4JJW8   H9J0A6   A0A194QQX1   A0A158NDP0   A0A194QRC6   A0A212F0G1   A0A0J7NFD4   A0A151WLU8   A0A151XEI7   B0XI43   A0A0P4WG45   A0A194Q8J5   B0XI42   A0A0J7L0X1   A0A3G1T1B2   F4W474   A0A195ET92   A0A195B6A6   A0A195BP85   A0A158NZK6   A0A194QE27   A0A194QA61   A0A023F7A3   A0A1L8D6X2   B0XCJ1   A0A026WRA5   A0A1S4G7W1   A0A076FT24   A0A139WKA8   A0A195CN33   A0A151X1L8   A0A0F6Q4J7   H9J0A4   A0A195CI97   A0A232EGH1   A0A0L7QT43   A0A0N0PDG0   A0A067R8A9   A0A1W4WBZ1   H9J0A5   E2A713   A0A195EK98   A0A0H4TG49   J9HTP4   H9J0A8   J9EB03   A0A195F4X3   A0A182GQQ8   A0A158NDN9   J9HJE4   A0A131Y3M1  

Pubmed

19121390    26354079    28756777    22118469    26227816    20074338    + More
22651552    23622113    24053512    21347285    21719571    25474469    24508170    30249741    17510324    24817326    18362917    19820115    28648823    24845553    20798317    26483478   

EMBL

BABH01027525    BABH01027529    BABH01027530    DQ443276    ABF51365.1    BABH01027538    + More
ODYU01003471    SOQ42306.1    BABH01036649    GEYN01000013    JAV02116.1    KQ460779    KPJ12396.1    KZ149989    PZC75627.1    KP899549    AKQ06148.1    KP237884    AKD01737.1    KPJ12400.1    AGBW02009651    OWR50236.1    JTDY01007189    KOB65394.1    JTDY01000876    KOB75589.1    KP237899    AKD01752.1    NWSH01001322    PCG71699.1    BABH01043464    BABH01043465    PZC75628.1    KP237873    AKD01726.1    PZC75626.1    BABH01044234    KP899551    AKQ06150.1    BABH01040078    EZ407131    ACX53694.1    BABH01027533    KQ459144    KPJ03686.1    KPJ12398.1    OWR50237.1    AK401931    BAM18553.1    KPJ03685.1    KPJ12399.1    GAIX01005455    JAA87105.1    KC007343    AGQ45608.1    KP899550    AKQ06149.1    ODYU01003911    SOQ43254.1    KP237875    AKD01728.1    SOQ43256.1    BABH01036642    JTDY01017041    KOB51868.1    PCG71700.1    BABH01019209    KQ461175    KPJ07892.1    ADTU01012731    KPJ07894.1    AGBW02011082    OWR47236.1    LBMM01005734    KMQ91250.1    KQ982944    KYQ48859.1    KQ982254    KYQ58773.1    DS233256    EDS28983.1    GDRN01065431    JAI64685.1    KQ459302    KPJ01719.1    EDS28982.1    LBMM01001364    KMQ96442.1    MG846919    AXY94771.1    GL887491    EGI71070.1    KQ981979    KYN31470.1    KQ976587    KYM79714.1    KQ976424    KYM88327.1    ADTU01004714    KPJ01716.1    KQ459249    KPJ02362.1    GBBI01001633    JAC17079.1    GEYN01000012    JAV02117.1    DS232698    EDS44853.1    KK107119    QOIP01000009    EZA58570.1    RLU18591.1    KF960797    AII21999.1    KQ971329    KYB28353.1    KQ977600    KYN01499.1    KQ982585    KYQ54299.1    KP237895    AKD01748.1    BABH01019201    BABH01019202    KQ977720    KYN00433.1    NNAY01004765    OXU17447.1    KQ414755    KOC61724.1    KQ460366    KPJ15602.1    KK852815    KDR15798.1    BABH01019208    GL437252    EFN70745.1    KQ978747    KYN28685.1    KP899548    AKQ06147.1    CH477964    EJY58013.1    BABH01019210    CH477766    EJY57916.1    KQ981820    KYN35129.1    JXUM01081117    KQ563228    KXJ74247.1    EJY58014.1    GEFM01002721    JAP73075.1   

Proteomes

UP000005204    UP000053240    UP000007151    UP000037510    UP000218220    UP000053268    + More
UP000005205    UP000036403    UP000075809    UP000002320    UP000007755    UP000078541    UP000078540    UP000053097    UP000279307    UP000007266    UP000078542    UP000215335    UP000053825    UP000027135    UP000192223    UP000000311    UP000078492    UP000008820    UP000069940    UP000249989   

PRIDE

H9J8I4    H9J8I5    Q1HPX6    H9J8J0    H9J8I9    H9J369    + More
H9JWW1    H9JWW0    H9JYK0    H9JWW7    H9J8I6    H9JWW6    H9J354    H9J355    H9J0A6    H9J0A4    H9J0A5    H9J0A8   

Pfam

PF00106   adh_short

Interpro

IPR002347   SDR_fam        + More
IPR036291   NAD(P)-bd_dom_sf       
IPR020904   Sc_DH/Rdtase_CS       

SUPFAM

SSF51735   SSF51735       

ProteinModelPortal

H9J8I4   H9J8I5   Q1HPX6   H9J8J0   H9J8I9   A0A2H1VNC8   + More
H9J369   A0A1L8D6N5   A0A194R949   A0A2W1BR60   A0A0H4TDA9   A0A0F6Q0W0   A0A194R584   A0A212F911   A0A0L7KQW0   A0A0L7LJP6   A0A0F6Q0X5   A0A2A4JIR0   H9JWW1   H9JWW0   A0A2W1BL60   A0A0F6Q2J9   A0A2W1BSK9   H9JYK0   A0A0H4TD16   H9JWW7   D2SNK3   H9J8I6   A0A194QJQ6   A0A194R3L5   A0A212F936   I4DKW3   A0A194R4F0   S4PIB4   U5KC20   A0A0H4TH26   H9JWW6   A0A2H1VSR5   A0A0F6Q4H7   A0A2H1VR53   H9J354   H9J355   A0A0L7K2F9   A0A2A4JJW8   H9J0A6   A0A194QQX1   A0A158NDP0   A0A194QRC6   A0A212F0G1   A0A0J7NFD4   A0A151WLU8   A0A151XEI7   B0XI43   A0A0P4WG45   A0A194Q8J5   B0XI42   A0A0J7L0X1   A0A3G1T1B2   F4W474   A0A195ET92   A0A195B6A6   A0A195BP85   A0A158NZK6   A0A194QE27   A0A194QA61   A0A023F7A3   A0A1L8D6X2   B0XCJ1   A0A026WRA5   A0A1S4G7W1   A0A076FT24   A0A139WKA8   A0A195CN33   A0A151X1L8   A0A0F6Q4J7   H9J0A4   A0A195CI97   A0A232EGH1   A0A0L7QT43   A0A0N0PDG0   A0A067R8A9   A0A1W4WBZ1   H9J0A5   E2A713   A0A195EK98   A0A0H4TG49   J9HTP4   H9J0A8   J9EB03   A0A195F4X3   A0A182GQQ8   A0A158NDN9   J9HJE4   A0A131Y3M1  

PDB

5ILO     E-value=2.17238e-29,     Score=320

KEGG

101746934    K00069 15-hydroxyprostaglandin dehydrogenase (NAD) [EC:1.1.1.141] | (RefSeq) 15-hydroxyprostaglandin

GO

GO:0016491   GO:0004022   GO:0005737  

SignalP

Position:   1 - 18,         Likelihood:  0.998740

 

 

Length:

286

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.15986

Exp number, first 60 AAs:

0.06426

Total prob of N-in:

0.00570

outside

1  -  286

 

 

Pi

309.765087

Theta

166.96763

Tajima's D

2.806327

CLR

0.290784

CSRT

0.968451577421129

Interpretation

Possibly Balancing Selection