Gene

KWMTBOMO02996

Pre Gene Modal

BGIBMGA003616

Annotation

PREDICTED:_phospholipid_scramblase_2_[Bombyx_mori]

Location

Bomo_Chr5(-):15330608-15336895      View in EpiBrowser

Full name

Phospholipid scramblase      

Location in the cell

Extracellular   Reliability : 1.183 PlasmaMembrane   Reliability : 1.233

CDS

ATGGATCTGAAAGTATTTGATCGTGAAACTGGAGTGGGCGATCGAGGAATCGATAATCCAGCTGCCACAGACGATTATGGATCCCACGTAAGACCTGATTTGGTAATTAGCGTTCAGCCGCAATCACATGGAACTCGTGCAGAATTACCAGTGACTACGGTCAACTGGCGCTCCAACCCTCGAGGTCAGTTCATCCCGGTACATGGATTGGACTTTCTAATTGGAGTTTCCAGTCTTCTAATACAACAGACCGTTGAGCTTGATGATCTGACTTCAAAAATAGAATCGGAGAATCGTTACATAGTGAGGGTACCGAATGGAGAAGCTTTGTACATCGGCAACGAAGTGTCGTGTCCAACTCAGAGATGTATCTGTGGGAATGGTCGAGCCTTTATGATGCATCTTCATGACAACACGAGGCAAGAGGCCATGGTGCTGAAGCGAAGGTTGGCAGGGGCATCTTGTTTGTGGCCTTGTCGACTGCAAGAAATGAAAGTGATAACGCCTCCAGGCGACTACGTGGGACGTATCCAACAAAGCTGTACATGGATGATACCAGAGTACAGGGTTAGGGACGCCAACGACCAGACCCTGTTCATTATTGAAGGTCCAGCCGTATTGAAGAGAAGTGCTTTGATGTTATCCGAGTTTAAGATTCTGACTGCAGATTCCTCGAGAATCGTGGGACGGATAGCCCATGGCTGGGATCGTAATCTCGTCAGCTTCGCGACAACTCTCCAAATCCCTGATACAGCTGTACAACCTAAACATAAAGCATTGCTACTGGCCGCTACGTTTTTATTGGAGTACACATATTTTGAAAGAACAAAATCGAGTTGTACGAGATGCCTTTTTTGCTGA

Protein

MDLKVFDRETGVGDRGIDNPAATDDYGSHVRPDLVISVQPQSHGTRAELPVTTVNWRSNPRGQFIPVHGLDFLIGVSSLLIQQTVELDDLTSKIESENRYIVRVPNGEALYIGNEVSCPTQRCICGNGRAFMMHLHDNTRQEAMVLKRRLAGASCLWPCRLQEMKVITPPGDYVGRIQQSCTWMIPEYRVRDANDQTLFIIEGPAVLKRSALMLSEFKILTADSSRIVGRIAHGWDRNLVSFATTLQIPDTAVQPKHKALLLAATFLLEYTYFERTKSSCTRCLFC

Description

May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

Cofactor

Ca(2+)

Similarity

Belongs to the phospholipid scramblase family.

Uniprot

A0A2A4JGQ3   A0A1E1VZT3   A0A2H1W9H4   A0A194PP65   A0A212EVF7   H9J279   + More
A0A0N0PAM0   A0A1B6J2B1   A0A1B6DVY3   A0A2J7QX24   A0A2J7QX19   V5GLD7   V5GX66   A0A1Y1NF14   A0A139WNT6   D6W758   A0A023FBA2   A0A067RC55   A0A224XHI0   A0A146LE77   A0A146KLW3   A0A2P8Y3W2   J3JUV8   N6T2A2   B3MEQ8   B4P7K7   A0A023FB97   B4J846   B3NSN2   B4MK84   A0A1W4U5M6   B4KQ27   Q28WS6   B4H6B7   A1Z8F5   B4ME12   A0A3B0JL62   Q8SZ85   B5RJ61   A0A0A1XPE8   A0A0Q9WBG8   A0A0L0BP84   A0A3B0J034   B4HN40   W8BRW9   R4WR60   A0A1L8EGK8   W8BED8   A0A0K8W9F6   A0A1I8PH54   A0A0Q9WP14   A0A034VDF6   A0A0K8UKJ5   A0A1I8NAH3   B4QB34   A0A0B4KEL2   A0A034V927   W8C1R3   A0A0N7ZXB1   A0A336LV26   E9GIA0   A0A0P5HUT3   W5J5J0   A0A0P5T9E0   A0A0P5A6Q2   A0A1Y1JWZ4   A0A067QG92   C3ZIU3   A0A182YJI1   A0A182SMD3   A0A1W4WF47   A0A1W4WQ33   A0A1B6HDV9   A0A1B6LRE2   A0A0P6CRD8   A0A0P6CLZ2   A0A182L446   A0A0P5SL04   A0A182R9A9   A0A060YVX0   A0A1L8E3L1   A0A1B6LTY2   T1IB30   A0A182X243   A0A182N7I8   A0A182I6A4   E0VXM0   A0A1S3KKV9   A0A0A9XAE0   A0A182VGT9   A0A2J7R040   A0A182QYG9   A0A2J7R027   A0A2D0R9Y6   A0A2J7R038   A0A1B6E985  

Pubmed

26354079    22118469    19121390    28004739    18362917    19820115    + More
25474469    24845553    26823975    29403074    22516182    23537049    17994087    17550304    15632085    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    25830018    26108605    24495485    23691247    25348373    25315136    22936249    21292972    20920257    23761445    18563158    25244985    20966253    24755649    20566863    25401762   

EMBL

NWSH01001547    PCG70898.1    GDQN01010821    JAT80233.1    ODYU01007111    SOQ49596.1    + More
KQ459597    KPI95097.1    AGBW02012195    OWR45472.1    BABH01007434    KQ461187    KPJ07340.1    GECU01014404    JAS93302.1    GEDC01020451    GEDC01007463    JAS16847.1    JAS29835.1    NEVH01009398    PNF33133.1    PNF33132.1    GALX01003562    JAB64904.1    GALX01003563    JAB64903.1    GEZM01003858    JAV96523.1    KQ971307    KYB29660.1    EFA11407.1    GBBI01000423    JAC18289.1    KK852554    KDR21466.1    GFTR01004481    JAW11945.1    GDHC01012834    JAQ05795.1    GDHC01021076    JAP97552.1    PYGN01000957    PSN38929.1    BT127023    AEE61985.1    APGK01047232    APGK01047233    KB741077    KB631792    ENN74254.1    ERL86119.1    CH902619    EDV35522.2    CM000158    EDW90042.1    GBBI01000428    JAC18284.1    CH916367    EDW01183.1    CH954179    EDV56534.1    CH963846    EDW72523.1    CH933808    EDW08129.1    CM000071    EAL26591.1    CH479213    EDW33341.1    AE013599    AAM68719.1    CH940662    EDW58777.1    OUUW01000001    SPP73976.1    AY071050    AAL48672.1    BT044335    ACH92400.1    GBXI01001849    JAD12443.1    KRF78479.1    JRES01001578    KNC21865.1    SPP73975.1    CH480816    EDW47344.1    GAMC01006907    JAB99648.1    AK418186    BAN21401.1    GFDG01001015    JAV17784.1    GAMC01006905    JAB99650.1    GDHF01004491    JAI47823.1    KRF97591.1    GAKP01019152    JAC39800.1    GDHF01025105    GDHF01023532    GDHF01018295    JAI27209.1    JAI28782.1    JAI34019.1    CM000362    CM002911    EDX06567.1    KMY92913.1    AGB93417.1    GAKP01019151    JAC39801.1    GAMC01006904    JAB99651.1    GDIP01203449    JAJ19953.1    UFQT01000126    SSX20523.1    GL732546    EFX80807.1    GDIQ01245465    LRGB01003375    JAK06260.1    KZS02915.1    ADMH02002096    ETN59256.1    GDIQ01095111    JAL56615.1    GDIP01203448    JAJ19954.1    GEZM01103143    GEZM01103142    JAV51526.1    KK853500    KDR07158.1    GG666629    EEN47544.1    GECU01034927    GECU01013232    JAS72779.1    JAS94474.1    GEBQ01013755    JAT26222.1    GDIQ01089294    JAN05443.1    GDIQ01089295    JAN05442.1    GDIQ01091689    JAL60037.1    FR915643    CDQ93644.1    GFDF01000838    JAV13246.1    GEBQ01012851    JAT27126.1    ACPB03021686    APCN01003602    DS235833    EEB18126.1    GBHO01025937    GBHO01025936    GDHC01020916    GDHC01012357    GDHC01004641    JAG17667.1    JAG17668.1    JAP97712.1    JAQ06272.1    JAQ13988.1    NEVH01008299    PNF34190.1    AXCN02000574    PNF34192.1    PNF34198.1    GEDC01002799    JAS34499.1   

Proteomes

UP000218220    UP000053268    UP000007151    UP000005204    UP000053240    UP000235965    + More
UP000007266    UP000027135    UP000245037    UP000019118    UP000030742    UP000007801    UP000002282    UP000001070    UP000008711    UP000007798    UP000192221    UP000009192    UP000001819    UP000008744    UP000000803    UP000008792    UP000268350    UP000037069    UP000001292    UP000095300    UP000095301    UP000000304    UP000000305    UP000076858    UP000000673    UP000001554    UP000076408    UP000075901    UP000192223    UP000075882    UP000075900    UP000193380    UP000015103    UP000076407    UP000075884    UP000075840    UP000009046    UP000087266    UP000075903    UP000075886    UP000221080   

PRIDE

H9J279    A1Z8F5    Q8SZ85   

Pfam

PF03803   Scramblase        + More
PF00023   Ank
PF02493   MORN

Interpro

IPR005552   Scramblase        + More
IPR002110   Ankyrin_rpt       
IPR003409   MORN       
IPR020683   Ankyrin_rpt-contain_dom       
IPR036770   Ankyrin_rpt-contain_sf       
IPR025659   Tubby-like_C       

SUPFAM

SSF48403   SSF48403        + More
SSF54518   SSF54518       

Gene 3D

1.25.40.20    

CDD

cd00204  ANK

ProteinModelPortal

A0A2A4JGQ3   A0A1E1VZT3   A0A2H1W9H4   A0A194PP65   A0A212EVF7   H9J279   + More
A0A0N0PAM0   A0A1B6J2B1   A0A1B6DVY3   A0A2J7QX24   A0A2J7QX19   V5GLD7   V5GX66   A0A1Y1NF14   A0A139WNT6   D6W758   A0A023FBA2   A0A067RC55   A0A224XHI0   A0A146LE77   A0A146KLW3   A0A2P8Y3W2   J3JUV8   N6T2A2   B3MEQ8   B4P7K7   A0A023FB97   B4J846   B3NSN2   B4MK84   A0A1W4U5M6   B4KQ27   Q28WS6   B4H6B7   A1Z8F5   B4ME12   A0A3B0JL62   Q8SZ85   B5RJ61   A0A0A1XPE8   A0A0Q9WBG8   A0A0L0BP84   A0A3B0J034   B4HN40   W8BRW9   R4WR60   A0A1L8EGK8   W8BED8   A0A0K8W9F6   A0A1I8PH54   A0A0Q9WP14   A0A034VDF6   A0A0K8UKJ5   A0A1I8NAH3   B4QB34   A0A0B4KEL2   A0A034V927   W8C1R3   A0A0N7ZXB1   A0A336LV26   E9GIA0   A0A0P5HUT3   W5J5J0   A0A0P5T9E0   A0A0P5A6Q2   A0A1Y1JWZ4   A0A067QG92   C3ZIU3   A0A182YJI1   A0A182SMD3   A0A1W4WF47   A0A1W4WQ33   A0A1B6HDV9   A0A1B6LRE2   A0A0P6CRD8   A0A0P6CLZ2   A0A182L446   A0A0P5SL04   A0A182R9A9   A0A060YVX0   A0A1L8E3L1   A0A1B6LTY2   T1IB30   A0A182X243   A0A182N7I8   A0A182I6A4   E0VXM0   A0A1S3KKV9   A0A0A9XAE0   A0A182VGT9   A0A2J7R040   A0A182QYG9   A0A2J7R027   A0A2D0R9Y6   A0A2J7R038   A0A1B6E985  

KEGG

101743369    no KO assigned | (RefSeq) phospholipid scramblase 2

GO

GO:0017128   GO:0017121  

PANTHER

PTHR23248  

Length:

286

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0943600000000001

Exp number, first 60 AAs:

6e-05

Total prob of N-in:

0.04469

outside

1  -  286

 

 

Pi

279.973367

Theta

171.311639

Tajima's D

1.844597

CLR

0.499804

CSRT

0.854357282135893

Interpretation

Uncertain