Gene

KWMTBOMO02944  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA003564

Annotation

PREDICTED:_ornithine_aminotransferase?_mitochondrial_[Papilio_polytes]

Location

Bomo_Chr5(+):14215686-14228411      View in EpiBrowser

Full name

Ornithine aminotransferase       + More
Ornithine aminotransferase, mitochondrial      

Alternative Name

Ornithine--oxo-acid aminotransferase

Location in the cell

Cytoplasmic   Reliability : 2.729

CDS

ATGGCTGAACAAAATTTGTCATCTAAAGAAATTTTCCAGTTGGAAGACAAATATGGTTGTAGAAATTACGCTCCCTTGCCTGTTGCTTTATGCCGAGGTGAAGGAGTGTTCGTGTGGGATGTCGAAGGAAAAAAGTATTATGATTTTTTAAGCGCCTACTCCGCAGTTAACCAAGGTCACTGCCACCCTAGAATAATTGAAGCTTTGAAGAAACAAGCTGATAATTTGACACTAGTGTCAAGAGCATTTTATTCCGATCAACTTGGCAAGTATGAAAAGTATATGACAGAGTTATTTGGATATGATCGCCTGCTTCCTATGAACACGGGTGTTGAAGGAGGTGAAAGTGCATGCAAGATAGCACGTAAATGGGGGTACGAAGTCAAGAAGATACCTGAAGGCCAAGCTAAGATAATTTTTGCGGAAGGAAACTTCTGGGGGCGAACTCTATCGGCGGTATCATCATCATCAGACCCAACCTGCTACCAGGGCTTCGGACCGTACATGCCGGGCTTCATTCTTATTCCCTACAACAACATCCCAGCTTTAGAGAAAGCTCTCCAAGATCCGACAGTCGCGGCTTACATGGTTGAACCGATTCAAGGAGAGGCAGGCGTCGTAATACCTGACGACGGCTATCTCAAGAAGGTTCGAGAGCTATGTACAAAGCACAACGTGTTGTGGATTGCGGACGAAGTACAGACTGGATTAGGTCGCACAGGCAAGTTGTTGGCTGTGGAACACGAAGGCGTGAAACCAGACATACTAATACTTGGCAAAGCACTCAGCGGGGGTGTCTTGCCTGTTTCCGCTGTTCTAACTAGCAACGACATTATGGATGTGATAAAGCCAGGCACTCACGGATCAACGTACGGAGGAAACCCTTTGGCGTGCGCTGTAGCCACAGAAGCTATTAAGGTGCTACTGGATGAGAAATTATCGGAAAACGCTGAGAGGATGGGCAAAATACTACGCGAAGAGCTGAGTCAGATACCAAAAACACAGATTCGTACAGTTCGAGGGAGGGGACTGATGTGTGCTATTGTAGTGGATGACAGCATTCCAGCATCGGAGTTGTGTCTCCGCCTGCGCGACAATGGCCTGCTAGCGAAGCCGACGCACGGACAGACCGTGCGCCTCGCGCCGCCGCTCGTCATCACAGAGGCACAGATACGAGACGGCGCTGATATCATCAGGAACGTCTTCCAAAGCTTTCAAAAATAA

Protein

MAEQNLSSKEIFQLEDKYGCRNYAPLPVALCRGEGVFVWDVEGKKYYDFLSAYSAVNQGHCHPRIIEALKKQADNLTLVSRAFYSDQLGKYEKYMTELFGYDRLLPMNTGVEGGESACKIARKWGYEVKKIPEGQAKIIFAEGNFWGRTLSAVSSSSDPTCYQGFGPYMPGFILIPYNNIPALEKALQDPTVAAYMVEPIQGEAGVVIPDDGYLKKVRELCTKHNVLWIADEVQTGLGRTGKLLAVEHEGVKPDILILGKALSGGVLPVSAVLTSNDIMDVIKPGTHGSTYGGNPLACAVATEAIKVLLDEKLSENAERMGKILREELSQIPKTQIRTVRGRGLMCAIVVDDSIPASELCLRLRDNGLLAKPTHGQTVRLAPPLVITEAQIRDGADIIRNVFQSFQK

Catalytic Activity

a 2-oxocarboxylate + L-ornithine = an L-alpha-amino acid + L-glutamate 5-semialdehyde

Cofactor

pyridoxal 5'-phosphate

Subunit

Homotetramer.

Similarity

Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

Keywords

Aminotransferase   Complete proteome   Mitochondrion   Pyridoxal phosphate   Reference proteome   Transferase   Transit peptide  

Feature

chain  Ornithine aminotransferase, mitochondrial

Uniprot

H9J227   A0A2W1BSE7   A0A2H1V208   A0A2A4K599   A0A194PP28   A0A2A4K504   + More
A0A1B6EZ27   A0A1B6GNX8   A0A068TKS2   A0A026W5N0   A0A3P8U0N8   A0A023ESS8   E9FVF0   A0A0S7KPC2   A0A067QWR3   A0A0F8AV93   A0A3B4AQM1   A0A2J7QY62   A0A3B4AS56   A0A1Q3F533   A0A2J7QY42   Q17AI0   A0A1Q3F622   A0A1Q3F698   A0A182GND5   E6ZHM0   A0A3P9NL21   A0A146X528   A0A2I4B428   A0A3P9NL53   A0A087XZD9   A0A1S4FA38   A0A1Q3F3S2   A0A3B3WLE1   A0A182NNF6   A0A1Q3F4V9   A0A1A8KFG0   A0A1A8BFP7   A0A1A7Z8J7   A0A182HXL2   A0A1A8RPL5   A0A1A8PMT2   A0A182YI01   A0A182FLV5   Q7Q2S8   A0A182WYI0   A0A182V1W3   A0A1A7Z2N1   B0WBA3   A0A182QX32   A0A3B4YQR4   A0A182WCP7   A7UUY2   A0A1A8G267   A0A182RKN2   A0A3B4V522   G3NDH0   A0A182MDK4   A0A0N0BK08   A0A182LI44   A0A034WFQ4   M4AQ51   A0A182SLB7   A0A2C9JJQ0   T1PDL2   A0A210PIA6   A0A1B6ML76   A0A1B6MT38   A0A1I8NTV1   A0A336K6D8   A0A182J635   A0A146X2X9   A0A3B3BXQ4   A0A1I8NBJ2   A0A0K8VPG6   A0A3B5B483   A0A2U9CTF9   A0A1D2M6T4   A0A3P9K9K3   H2M0Y8   A0A068XGC8   K1Q1I3   A0A3B1J0N7   A0A3P9IXL5   A0A1S3QJA5   B5X1S8   A0A3P9IXN2   A0A2D0S7M8   A0A1S3N5V9   A0A0L0C7X4   A0A3P8WPY9   Q7ZX40   A0A0P4VUE2   F4WR60   A0A310S4E6   B4IIP0   Q28FA4   A0A1L8FIZ3   Q9VW26   F8W5L3  

EC Number

2.6.1.13

Pubmed

19121390    28756777    26354079    24508170    24945155    21292972    + More
24845553    25835551    25463417    17510324    26483478    25244985    12364791    14747013    17210077    20966253    25348373    23542700    15562597    28812685    29451363    25315136    27289101    17554307    22992520    25329095    20433749    26108605    24487278    21719571    17994087    20431018    27762356    10731132    12537572    12537569    23594743   

EMBL

BABH01007531    BABH01007532    KZ149992    PZC75566.1    ODYU01000103    SOQ34304.1    + More
NWSH01000167    PCG78852.1    KQ459597    KPI95062.1    PCG78853.1    GECZ01026564    JAS43205.1    GECZ01005650    JAS64119.1    HG965792    CDO39388.1    KK107390    EZA51382.1    GAPW01001255    JAC12343.1    GL732525    EFX88542.1    GBYX01202367    JAO79073.1    KK852923    KDR13737.1    KQ042638    KKF12738.1    NEVH01009368    PNF33504.1    GFDL01012406    JAV22639.1    PNF33503.1    CH477335    EAT43242.1    GFDL01012030    JAV23015.1    GFDL01012012    JAV23033.1    JXUM01076259    KQ562935    KXJ74780.1    FQ310507    CBN81554.1    GCES01049881    JAR36442.1    AYCK01001153    GFDL01012897    JAV22148.1    GFDL01012445    JAV22600.1    HAED01000950    HAEE01010973    SBR31023.1    HADZ01001787    HAEA01002762    SBP65728.1    HADY01000333    HAEJ01003459    SBP38818.1    APCN01005321    HAEH01005690    HAEI01009507    SBS07971.1    HAEF01007062    HAEG01008612    SBR82314.1    AAAB01008968    EAA13194.4    HADW01001343    HADX01014875    SBP37107.1    DS231878    EDS42247.1    AXCN02001909    EDO63496.1    HAEB01018780    HAEC01000977    SBQ65307.1    AXCM01006583    KQ435710    KOX79798.1    GAKP01005425    GAKP01005424    GAKP01005423    GAKP01005422    JAC53529.1    KA646784    AFP61413.1    NEDP02076661    OWF36207.1    GEBQ01003352    JAT36625.1    GEBQ01000928    JAT39049.1    UFQS01000118    UFQT01000118    SSX00031.1    SSX20411.1    GCES01049882    JAR36441.1    GDHF01011540    JAI40774.1    CP026260    AWP17882.1    LJIJ01003321    ODM88683.1    JH815769    EKC25219.1    BT044997    ACI33259.1    JRES01000760    KNC28518.1    BC045249    AAH45249.1    GDRN01096103    JAI59403.1    GL888284    EGI63287.1    KQ777939    OAD52025.1    CH480844    EDW49811.1    AAMC01073582    BC167123    BC167345    CR762076    AAI67123.1    AAI67345.1    CAJ81924.1    CM004478    OCT71560.1    AE014296    AY047517    AL953868    CABZ01057903    CABZ01057904   

Proteomes

UP000005204    UP000218220    UP000053268    UP000053097    UP000265080    UP000000305    + More
UP000027135    UP000261520    UP000235965    UP000008820    UP000069940    UP000249989    UP000242638    UP000192220    UP000028760    UP000261480    UP000075884    UP000075840    UP000076408    UP000069272    UP000007062    UP000076407    UP000075903    UP000002320    UP000075886    UP000261360    UP000075920    UP000075900    UP000261420    UP000007635    UP000075883    UP000053105    UP000075882    UP000002852    UP000075901    UP000076420    UP000242188    UP000095300    UP000075880    UP000261560    UP000095301    UP000261400    UP000246464    UP000094527    UP000265180    UP000001038    UP000005408    UP000018467    UP000265200    UP000087266    UP000221080    UP000037069    UP000265120    UP000007755    UP000001292    UP000008143    UP000186698    UP000000803    UP000000437   

PRIDE

H9J227    Q9VW26   

Pfam

PF00202   Aminotran_3        + More
PF01852   START

Interpro

IPR015424   PyrdxlP-dep_Trfase        + More
IPR010164   Orn_aminotrans       
IPR015421   PyrdxlP-dep_Trfase_major       
IPR015422   PyrdxlP-dep_Trfase_dom1       
IPR005814   Aminotrans_3       
IPR034758   Orn_aminotrans_mito       
IPR002913   START_lipid-bd_dom       
IPR023393   START-like_dom_sf       
IPR041949   START_STARD7       

SUPFAM

SSF53383   SSF53383       

Gene 3D

3.40.640.10     3.90.1150.10     3.30.530.20    

CDD

cd00610  OAT_like
cd08911  START_STARD7-like

ProteinModelPortal

H9J227   A0A2W1BSE7   A0A2H1V208   A0A2A4K599   A0A194PP28   A0A2A4K504   + More
A0A1B6EZ27   A0A1B6GNX8   A0A068TKS2   A0A026W5N0   A0A3P8U0N8   A0A023ESS8   E9FVF0   A0A0S7KPC2   A0A067QWR3   A0A0F8AV93   A0A3B4AQM1   A0A2J7QY62   A0A3B4AS56   A0A1Q3F533   A0A2J7QY42   Q17AI0   A0A1Q3F622   A0A1Q3F698   A0A182GND5   E6ZHM0   A0A3P9NL21   A0A146X528   A0A2I4B428   A0A3P9NL53   A0A087XZD9   A0A1S4FA38   A0A1Q3F3S2   A0A3B3WLE1   A0A182NNF6   A0A1Q3F4V9   A0A1A8KFG0   A0A1A8BFP7   A0A1A7Z8J7   A0A182HXL2   A0A1A8RPL5   A0A1A8PMT2   A0A182YI01   A0A182FLV5   Q7Q2S8   A0A182WYI0   A0A182V1W3   A0A1A7Z2N1   B0WBA3   A0A182QX32   A0A3B4YQR4   A0A182WCP7   A7UUY2   A0A1A8G267   A0A182RKN2   A0A3B4V522   G3NDH0   A0A182MDK4   A0A0N0BK08   A0A182LI44   A0A034WFQ4   M4AQ51   A0A182SLB7   A0A2C9JJQ0   T1PDL2   A0A210PIA6   A0A1B6ML76   A0A1B6MT38   A0A1I8NTV1   A0A336K6D8   A0A182J635   A0A146X2X9   A0A3B3BXQ4   A0A1I8NBJ2   A0A0K8VPG6   A0A3B5B483   A0A2U9CTF9   A0A1D2M6T4   A0A3P9K9K3   H2M0Y8   A0A068XGC8   K1Q1I3   A0A3B1J0N7   A0A3P9IXL5   A0A1S3QJA5   B5X1S8   A0A3P9IXN2   A0A2D0S7M8   A0A1S3N5V9   A0A0L0C7X4   A0A3P8WPY9   Q7ZX40   A0A0P4VUE2   F4WR60   A0A310S4E6   B4IIP0   Q28FA4   A0A1L8FIZ3   Q9VW26   F8W5L3  

PDB

2OAT     E-value=1.19387e-163,     Score=1479

KEGG

101738901    K00819 ornithine--oxo-acid transaminase [EC:2.6.1.13] | (RefSeq) ornithine aminotransferase, mitocho

PATHWAY

00330    Arginine and proline metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0004587   GO:0030170   GO:0055129   GO:0019544   GO:0010121   GO:0005737   GO:0008289   GO:0005739   GO:0005759   GO:0006591   GO:0008483   GO:0003824   GO:0004672   GO:0006310   GO:0003909   GO:0051103   GO:0003677   GO:0006281   GO:0048384  

PANTHER

PTHR11986:SF18  

Subcellular location

Mitochondrion matrix  

Length:

407

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.02066

Exp number, first 60 AAs:

0.00351

Total prob of N-in:

0.01045

outside

1  -  407

 

 

Pi

189.040199

Theta

176.570262

Tajima's D

0.430017

CLR

1.073894

CSRT

0.494525273736313

Interpretation

Uncertain