Gene

KWMTBOMO02902  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA003648

Annotation

putative_ubiquitin_protein_ligase_[Danaus_plexippus]

Location

Bomo_Chr5(-):13516225-13522398      View in EpiBrowser

Location in the cell

Nuclear   Reliability : 1.962 PlasmaMembrane   Reliability : 1.774

CDS

ATGTATTCATTCGAGGGAGACTTTAGGCGAAAACCCCAACAAAATTTAGCAGGTGCAAGCGCGGCACGAAAGACCGATAGAGACTCTTTGATTCAACAAACACAGTTACAAAGACAAAAACGAGAGGAACACCGAAAACGTTTAAACAGTGTTATAAAAATTCAAGCATATTTTAGAAGCTACTTAACCAGAAAAAAATGTAAACAAGTAGAAAGGGACCAATTTGATGATATGTTTCCTAGAATTAATGTAGAAGATCAAACAACAATCTCAGCACTGTTAGCAAAAATATTTTTCTTCTATGATGACAAAGCTGATGTTTCTAGATTGGTATCAATATCACAATTGTTGTTAAAACAATGGAAAAAGGTCTTCCACAACAGTGGCTCTAGTATACAGATAAGAAGATTACTAGCATTACATTTGCGACTATTGAAGTATAACACAGAGGTGCCTTTAGCAGTTCCACTCAGAATGTTTGAAGTATTCACATCCACTAGTACAGTAGAAGCAGCAATGAACTGTGATGAGGCACTGAGATTTGTTGCCAATACATTCTTGTATTTAATTAAAAGAGGCTATTTCATGGATCTGTGTAAATTAATATGTGAAAAGACCCCACCAATGTATGGTCCATCACCAAACCCACCCACCCCATTAAGCGGAGCACTTTTAGAGTTAATTCAGCGCCCTCTGTCACTGATCCTGCGAGTGAACATTCCTCAGTATGAAGATACAGTAACAACAGAGTTTACTGCGGCATTTTTGTGCAATCCGTATCCAGAACCAGTAGAAATGTTTATATTACCATCTCTAGCACAGGATACCACAAAGAAACTATCATTCTTAGCATTAATAAAGTGTTTACAAGACGACAACAAATATCATAGTAAAAAGATTATAAACGATTCTTGGTTATTGCATTCGGTTTTGGTTTTAGAGCCAAAGCAATTTATAAGTGAAATAAAAAATATTGACAATACAAGATTGCCAAGCAATAGAATAGTAATAGAATACCTTAAGGTAATAGCTAGATTGACTGAGAATGTGTGCAACAAACAAATCACCTACGAATTTGAAGACTCACTGTACAGTCAAGAAACTGCAGCGGACAAAGATGATGAAAGTGACAGCGAAACCGAACCGAATCCCACCTCTATTCGTGAACAGATGCTGCTGACGCGGTGTATTGAATTATTGAATGATCCAGAAAGATGCATTATGGTCACCATATCTCAAATAACAGATAATGATTTAAGTGAAGAATTTTTAGAGTACATGTCTGAGATCTGTCACAATTTGCTTTTGAGTCATCGTATGGCTTTGCATAAGTACAGGTTATTGTATACGCTAGCATTTAAACCGATATTCTTACGAGGTCTATGGCGCTGGTTGAGTAATATGAACCACGCTTCCTCGTTCGGTGGTTCGTCCACGTCTCTCCTGTCTGCGTTGTCCCGCGGTATGGGTGCCGAAACTTCTGTGATAGGTGTTCATAGACTACTGGCACCTTTGGCTGTCTTCTGCGCCTTGTTCTCGCTATTAATCGGAACCTTACACGATACGGAGTTCTGCAAAGATATGGACGATGATGAGAAAATGAGCGTGTTGAACGCCGGCGGTGGGGGTGGCAGGATTCACGCGTTTGAGTTCTCGGAACTTGGCGGTCTCTGCAGAACGTTACGCCAAGTCTGTCTCGGTCTCATAGAACTGGCCTACCCTGAGTCGAGGCTCACTGCCTGTGGACTGTACAAAGATGCTGTGGGTTACACTGACGTCGAAATGTCTGGCAAGAATAGGACGCCAGCGTGGTCACATCTATTTAAAGTAAGTTCAATTTTCTAA

Protein

MYSFEGDFRRKPQQNLAGASAARKTDRDSLIQQTQLQRQKREEHRKRLNSVIKIQAYFRSYLTRKKCKQVERDQFDDMFPRINVEDQTTISALLAKIFFFYDDKADVSRLVSISQLLLKQWKKVFHNSGSSIQIRRLLALHLRLLKYNTEVPLAVPLRMFEVFTSTSTVEAAMNCDEALRFVANTFLYLIKRGYFMDLCKLICEKTPPMYGPSPNPPTPLSGALLELIQRPLSLILRVNIPQYEDTVTTEFTAAFLCNPYPEPVEMFILPSLAQDTTKKLSFLALIKCLQDDNKYHSKKIINDSWLLHSVLVLEPKQFISEIKNIDNTRLPSNRIVIEYLKVIARLTENVCNKQITYEFEDSLYSQETAADKDDESDSETEPNPTSIREQMLLTRCIELLNDPERCIMVTISQITDNDLSEEFLEYMSEICHNLLLSHRMALHKYRLLYTLAFKPIFLRGLWRWLSNMNHASSFGGSSTSLLSALSRGMGAETSVIGVHRLLAPLAVFCALFSLLIGTLHDTEFCKDMDDDEKMSVLNAGGGGGRIHAFEFSELGGLCRTLRQVCLGLIELAYPESRLTACGLYKDAVGYTDVEMSGKNRTPAWSHLFKVSSIF

Catalytic Activity

S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.

Uniprot

H9J2B1   A0A1E1WBV5   A0A1E1WF09   A0A2H1WDG2   A0A2A4K259   A0A2W1BQ10   + More
A0A0N1IFM7   A0A212ELL8   A0A0L7KXC7   A0A2J7PQJ9   A0A0J7KYF6   A0A067QLC7   A0A0M9A9L3   A0A151IE76   E2C2T7   A0A026WIC3   A0A151J589   E2A6Z2   A0A087ZWH0   A0A195BXQ3   F4WYP1   A0A151JTB7   A0A158NM58   A0A232F3V6   K7IPJ0   A0A0L7QV74   A0A154PTM6   A0A151XJL4   E0VR04   A0A1B6EYS1   A0A2P8YUZ8   A0A0C9RNM0   A0A1B6CSA4   E9GES0   A0A1A9YRQ8   A0A1B0BXF4   A0A2H8TTS2   A0A0K8W0W7   A0A1S3JYX9   A0A0P5SS70   A0A0P5KFZ8   A0A0P5SQ25   A0A2S2PWD8   A0A0P5DBM8   A0A1I8NAL4   A0A0N8ACT8   T1PGI9   A0A0N7ZJK8   T1J5A0   A0A0P5EH80   V9ILQ8   A0A0P4YCM7   A0A0P5D6X4   A0A0P5WB07   A0A0P5DWD5   A0A0P5AQZ6   A0A210R166   A0A0N8AC83   A0A0P5CVL5   A0A0P6IG15   A0A0N8CI03   A0A2C9KEQ7   A0A0P5DE48   A0A0P5DGK6   A0A0P5AIP6   R7TFZ0   E9J4K9   B4LK42   B3NQG8   A0A2J7PQJ8   B3MDM7   T1K5B5   B4PAW3   B4QBK1   B4I2F2   Q9W196   A0A0P5T6I9   A0A0L8H445   A0A0P5T8J1   A0A0P5AGK0   T1GTQ9   A0A336MW41   A0A336MWB4   A0A182JPA3   A0A1B6LL86   J9JJG6   A0A1W4V057   A0A0M3QV71   W5UD75   A0A3B3SQZ9   S4R7H0   A0A0B7A7A1   A0A1J1I3Y3   W4XSK8   A0A087T880   A0A1A8ESE4   A0A060VW70  

Pubmed

19121390    28756777    26354079    22118469    26227816    24845553    + More
20798317    24508170    30249741    21719571    21347285    28648823    20075255    20566863    29403074    21292972    25315136    28812685    15562597    23254933    21282665    17994087    17550304    22936249    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    23127152    29240929    24755649   

EMBL

BABH01007596    BABH01007597    BABH01007598    BABH01007599    BABH01007600    GDQN01006625    + More
JAT84429.1    GDQN01005476    JAT85578.1    ODYU01007914    SOQ51109.1    NWSH01000285    PCG77760.1    KZ149960    PZC76361.1    KQ460226    KPJ16427.1    AGBW02014037    OWR42368.1    JTDY01004837    KOB67689.1    NEVH01022635    PNF18607.1    LBMM01002028    KMQ95376.1    KK853201    KDR09906.1    KQ435713    KOX79296.1    KQ977890    KYM98999.1    GL452203    EFN77772.1    KK107238    QOIP01000007    EZA54854.1    RLU20360.1    KQ980039    KYN18133.1    GL437208    EFN70795.1    KQ976395    KYM93075.1    GL888455    EGI60676.1    KQ981960    KYN31906.1    ADTU01020292    NNAY01001008    OXU25516.1    KQ414727    KOC62552.1    KQ435127    KZC14784.1    KQ982060    KYQ60579.1    DS235442    EEB15810.1    GECZ01026610    JAS43159.1    PYGN01000344    PSN48070.1    GBYB01010005    JAG79772.1    GEDC01020879    JAS16419.1    GL732541    EFX82031.1    JXJN01022202    GFXV01005821    MBW17626.1    GDHF01007517    JAI44797.1    GDIP01141382    JAL62332.1    GDIQ01184745    JAK66980.1    GDIP01140274    JAL63440.1    GGMS01000568    MBY69771.1    GDIP01160034    JAJ63368.1    GDIP01160033    JAJ63369.1    KA647922    AFP62551.1    GDIP01239073    JAI84328.1    JH431855    GDIP01160032    JAJ63370.1    JR053746    AEY62010.1    GDIP01239072    JAI84329.1    GDIP01160035    JAJ63367.1    GDIP01089784    JAM13931.1    GDIP01156480    JAJ66922.1    GDIP01209669    JAJ13733.1    NEDP02000888    OWF54780.1    GDIP01161673    JAJ61729.1    GDIP01181116    JAJ42286.1    GDIQ01006569    JAN88168.1    GDIP01129823    JAL73891.1    GDIP01158872    JAJ64530.1    GDIP01160031    JAJ63371.1    GDIP01211927    JAJ11475.1    AMQN01013239    KB310056    ELT92644.1    GL768105    EFZ12282.1    CH940648    EDW60631.1    CH954179    EDV56971.1    PNF18609.1    CH902619    EDV37490.1    CAEY01001585    CM000158    EDW92503.1    CM000362    CM002911    EDX08519.1    KMY96291.1    CH480820    EDW53947.1    AE013599    AY069726    AAF47181.1    AAL39871.1    GDIP01132585    JAL71129.1    KQ419326    KOF83972.1    GDIP01133776    JAL69938.1    GDIP01212714    JAJ10688.1    CAQQ02018150    CAQQ02018151    UFQS01003124    UFQT01003124    SSX15237.1    SSX34612.1    UFQT01002994    SSX34410.1    GEBQ01015496    JAT24481.1    ABLF02033481    ABLF02033487    CP012524    ALC41873.1    JT412358    AHH39815.1    HACG01029989    CEK76854.1    CVRI01000040    CRK94907.1    AAGJ04132473    KK113905    KFM61319.1    HAEB01002956    HAEC01008838    SBQ49483.1    FR904266    CDQ56590.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000007151    UP000037510    UP000235965    + More
UP000036403    UP000027135    UP000053105    UP000078542    UP000008237    UP000053097    UP000279307    UP000078492    UP000000311    UP000005203    UP000078540    UP000007755    UP000078541    UP000005205    UP000215335    UP000002358    UP000053825    UP000076502    UP000075809    UP000009046    UP000245037    UP000000305    UP000092443    UP000092460    UP000085678    UP000095301    UP000242188    UP000076420    UP000014760    UP000008792    UP000008711    UP000007801    UP000015104    UP000002282    UP000000304    UP000001292    UP000000803    UP000053454    UP000015102    UP000075881    UP000007819    UP000192221    UP000092553    UP000221080    UP000261540    UP000245300    UP000183832    UP000007110    UP000054359    UP000193380   

PRIDE

H9J2B1    Q9W196   

Pfam

PF00632   HECT        + More
PF00612   IQ
PF02460   Patched
PF10221   DUF2151
PF02668   TauD

Interpro

IPR035983   Hect_E3_ubiquitin_ligase        + More
IPR000569   HECT_dom       
IPR000048   IQ_motif_EF-hand-BS       
IPR003392   Ptc/Disp       
IPR000731   SSD       
IPR019355   Cell_cycle_regulator_Mat89Bb       
IPR042098   TauD-like_sf       
IPR003819   TauD/TfdA-like       

SUPFAM

SSF56204   SSF56204       

Gene 3D

3.60.130.10    

CDD

cd00078  HECTc

ProteinModelPortal

H9J2B1   A0A1E1WBV5   A0A1E1WF09   A0A2H1WDG2   A0A2A4K259   A0A2W1BQ10   + More
A0A0N1IFM7   A0A212ELL8   A0A0L7KXC7   A0A2J7PQJ9   A0A0J7KYF6   A0A067QLC7   A0A0M9A9L3   A0A151IE76   E2C2T7   A0A026WIC3   A0A151J589   E2A6Z2   A0A087ZWH0   A0A195BXQ3   F4WYP1   A0A151JTB7   A0A158NM58   A0A232F3V6   K7IPJ0   A0A0L7QV74   A0A154PTM6   A0A151XJL4   E0VR04   A0A1B6EYS1   A0A2P8YUZ8   A0A0C9RNM0   A0A1B6CSA4   E9GES0   A0A1A9YRQ8   A0A1B0BXF4   A0A2H8TTS2   A0A0K8W0W7   A0A1S3JYX9   A0A0P5SS70   A0A0P5KFZ8   A0A0P5SQ25   A0A2S2PWD8   A0A0P5DBM8   A0A1I8NAL4   A0A0N8ACT8   T1PGI9   A0A0N7ZJK8   T1J5A0   A0A0P5EH80   V9ILQ8   A0A0P4YCM7   A0A0P5D6X4   A0A0P5WB07   A0A0P5DWD5   A0A0P5AQZ6   A0A210R166   A0A0N8AC83   A0A0P5CVL5   A0A0P6IG15   A0A0N8CI03   A0A2C9KEQ7   A0A0P5DE48   A0A0P5DGK6   A0A0P5AIP6   R7TFZ0   E9J4K9   B4LK42   B3NQG8   A0A2J7PQJ8   B3MDM7   T1K5B5   B4PAW3   B4QBK1   B4I2F2   Q9W196   A0A0P5T6I9   A0A0L8H445   A0A0P5T8J1   A0A0P5AGK0   T1GTQ9   A0A336MW41   A0A336MWB4   A0A182JPA3   A0A1B6LL86   J9JJG6   A0A1W4V057   A0A0M3QV71   W5UD75   A0A3B3SQZ9   S4R7H0   A0A0B7A7A1   A0A1J1I3Y3   W4XSK8   A0A087T880   A0A1A8ESE4   A0A060VW70  

KEGG

101742898    K10589 ubiquitin-protein ligase E3 C [EC:2.3.2.26] | (RefSeq) ubiquitin-protein ligase E3C

GO

GO:0004842   GO:0016021   GO:0016874   GO:0006511   GO:0061631   GO:0000209   GO:0016491   GO:0031624   GO:0005737   GO:0005634   GO:0005515   GO:0003724   GO:0006401   GO:0003676   GO:0005524   GO:0007169   GO:0016020   GO:0004713   GO:0006281   GO:0048384  

Length:

614

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

13.78542

Exp number, first 60 AAs:

0.00013

Total prob of N-in:

0.02524

outside

1  -  614

 

 

Pi

254.635659

Theta

194.714021

Tajima's D

1.030648

CLR

0.193599

CSRT

0.666016699165042

Interpretation

Uncertain