Gene

KWMTBOMO02831

Pre Gene Modal

BGIBMGA003675

Annotation

PREDICTED:_nucleoside_diphosphate_kinase_7_[Papilio_polytes]

Location

Bomo_Chr5(-):12247019-12250795      View in EpiBrowser

Full name

Nucleoside diphosphate kinase 7       + More
Nucleoside diphosphate kinase      

Alternative Name

nm23-M7
nm23-R7
nm23-H7

Location in the cell

Cytoplasmic   Reliability : 1.785

CDS

ATGGAAGAATCTTACGCTGATAAATATTCTTTCATTGGCGAATGGTATGACAATCAAGCAAATTTAAAACGCCGGTTTAACATTTTTTACTACCCTTCTGATGATACTATAGAAATGTATGACTTAAAAAGTCGAAAAACGTTTGTGAAAAGAGTTAAAGTAAATGGTGTAACTTTAGATAGGTTTTATATTGGTTGTACTTTAAGTATATTAGGTCGTCTTATAAAAATAATTGACTTCGCTTGTGACCATACACGAAAGAAGTTGCACAATGAAATGCAAGTAACTTTTGCTATGATTAAACCCCTTCCAACTGAAATCGTTGGTAAAATTTTAAGTCACTTTCATGAGCATGGTTTGCGGGTAACAAAAATGAAGAAATCACGACTGACTGCTGAAGATATTAATATTTTGTATAGATCTCAGGTCACAGATCCTACATTTCCGTTTCTTTTAGATTACCTCACAGGAGAAATGGTTTATGGTTTAGAGTTAGTTGGAAGAGATGCAGTACTAGTATGTATTAAACTCCTTGGTGATAAAGATCCAAGAAAGGCTGAAATAGGGTCAATAAGAGCTCTCTATGGTACAGATCCTGTTAAAAATTGTGTTCATGCATCAAGCTCATCAGAATCGGCAATAGAGGATATAGAATATTTTTTTCCACCTCCACCTCTAAATTCGACACGACTTTGTCTGACTGCAACTCTCTCGAACTGCACCCTTTGTATAGTAAAGCCTCATGCAATACTAGAGGGAAAACTAGGTGCAGCTTTGGAAGCCATTGATAAGGGTGGTTTCAATGTAACTGCCCTCTACATGCTGATTGTTGAAAATATTAATGCAGCTGAATTTTATGAAGTTTATAAAGGCATTGTGCCTGAATACAAGGGTATGGTTGAAGAATTGTCGAGTGGCCCTTGCGTGGCTATGGAAATAGTAGCGAAAAATAAAAATGTTAACACTGCTGTTGAATTTAGAAAATTAGTAGGTCCTTCTGATCCTGAGATTGCAAGATTACTTCGACCGGATACCCTGAGAGCAAAGTTGGGAAAAACGAAAGTACAAAACGCAGTTCACTGTAGCGATTTAGCAGAAGATGGATTACTAGAAGTTGAATACTTTTTCAAGATCTTAGCATTATAA

Protein

MEESYADKYSFIGEWYDNQANLKRRFNIFYYPSDDTIEMYDLKSRKTFVKRVKVNGVTLDRFYIGCTLSILGRLIKIIDFACDHTRKKLHNEMQVTFAMIKPLPTEIVGKILSHFHEHGLRVTKMKKSRLTAEDINILYRSQVTDPTFPFLLDYLTGEMVYGLELVGRDAVLVCIKLLGDKDPRKAEIGSIRALYGTDPVKNCVHASSSSESAIEDIEYFFPPPPLNSTRLCLTATLSNCTLCIVKPHAILEGKLGAALEAIDKGGFNVTALYMLIVENINAAEFYEVYKGIVPEYKGMVEELSSGPCVAMEIVAKNKNVNTAVEFRKLVGPSDPEIARLLRPDTLRAKLGKTKVQNAVHCSDLAEDGLLEVEYFFKILAL

Catalytic Activity

a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP
a ribonucleoside 5'-diphosphate + ATP = a ribonucleoside 5'-triphosphate + ADP

Cofactor

Mg(2+)

Similarity

Belongs to the NDK family.

Keywords

ATP-binding   Complete proteome   Kinase   Magnesium   Metal-binding   Nucleotide metabolism   Nucleotide-binding   Reference proteome   Transferase   Alternative splicing  

Feature

chain  Nucleoside diphosphate kinase 7
splice variant  In isoform 2.

Uniprot

A0A2W1BTV9   A0A2A4JZY2   A0A2H1X336   A0A212F1W4   A0A194PNE6   A0A0N1ITX7   + More
A0A2A3E3V5   A0A087ZWW7   C4B8X0   A0A1B6FBE1   A0A026VWD2   E9J644   A0A1B6LER2   A0A1B6KTD4   A0A2J7QC66   A0A2B4S5Z9   A0A2J7QC52   A0A2J7QC53   A0A151XC28   A0A1S3F4U5   F4X6X1   A0A158NFY0   J9HLV5   R7TZK1   A0A067RKK2   A0A2Y9RKT2   A0A1B6C8C7   A0A0C9QCH4   A7SP47   K9IJ52   A0A2K5ZQK5   A0A096N6Q5   G3VTT6   G7MFA1   E2BWD1   G3TAM2   A0A3P8ZQL6   A0A2K6LGL2   A0A2K5IWR3   Q05BM9   H2MLS7   A0A0D9RF97   A0A2K6BTG8   A0A2K5X5S7   H9FTL1   A0A2K5LKL9   Q80UP4   A0A154P1Y2   C1BYW3   F1LNL9   A0A210R3D6   E2AMH5   A0A3P9LEE9   A0A384CI25   H2ZR10   A0A0L7R3P5   G9KDJ4   A0A195F2D0   Q3UMG6   A0A2K6UUV2   U3E823   A0A2U3Y894   W4Z1L5   W5KX55   G1RY63   Q6PAG9   Q9QXL8   A0A3P8XTR1   F7GQ16   U6CNG2   A0A2K5PVF6   A0A3P9I4A5   H3B3B9   F1PMF2   H0V2N4   H2Q0K0   G1LYF0   Q9QXL7   A0A2J8SAT5   A0A2I2YP06   A0A2R9BXY8   Q9Y5B8   A0A3P8R4P9   A0A384CI35   K9K275   M3WB88   A0A3P9BMP9   A0A3B4XQE1   A0A078A2E8   A0A287AHH1   A0A0P6J402   I3MHE9   I3KT89   A0A2Y9JT67   F6Q3R3   A0A2Y9S527   A0A341B947   G1TFZ9  

EC Number

2.7.4.6

Pubmed

28756777    22118469    26354079    12203911    12481130    15114417    + More
19527718    24508170    21282665    21719571    21347285    23382650    23254933    24845553    17615350    21709235    22002653    20798317    25069045    15489334    17554307    17431167    25319552    20433749    15057822    28812685    23236062    10349636    11042159    11076861    11217851    12466851    12040188    16141073    19468303    21183079    25243066    25329095    9215903    16341006    21993624    16136131    20010809    20966424    22398555    22722832    14702039    16710414    14654843    21269460    24813606    19892987    17975172    25186727    17495919   

EMBL

KZ150007    PZC75173.1    NWSH01000356    PCG77073.1    ODYU01013029    SOQ59646.1    + More
AGBW02010786    OWR47735.1    KQ459597    KPI94956.1    KQ435726    KOX78158.1    KZ288388    PBC26395.1    EAAA01000095    AB501294    BAH59279.1    GECZ01022179    JAS47590.1    KK107770    EZA47831.1    GL768221    EFZ11731.1    GEBQ01017802    JAT22175.1    GEBQ01025316    JAT14661.1    NEVH01016292    PNF26162.1    LSMT01000176    PFX24463.1    PNF26163.1    PNF26165.1    KQ982314    KYQ57899.1    GL888818    EGI57903.1    ADTU01014832    AMCR01022026    EJY64649.1    AMQN01010045    KB306898    ELT99378.1    KK852415    KDR24401.1    GEDC01027552    JAS09746.1    GBYB01001004    JAG70771.1    DS469728    EDO34502.1    GABZ01006590    JAA46935.1    AHZZ02017791    AHZZ02017792    AHZZ02017793    AHZZ02017794    AHZZ02017795    AHZZ02017796    AEFK01155615    AEFK01155616    AEFK01155617    AEFK01155618    AEFK01155619    AEFK01155620    AEFK01155621    CM001253    EHH15798.1    GL451103    EFN80035.1    BC038021    AAH38021.1    AQIB01113215    AQIB01113216    AQIB01113217    AQIA01000664    AQIA01000665    AQIA01000666    AQIA01000667    JSUE03003452    JSUE03003453    JSUE03003454    JU334214    JU334215    JU334216    JU334217    JU334218    JU334219    JU475332    AFE77970.1    AFH32136.1    BC049225    AAH49225.1    KQ434786    KZC05140.1    BT079792    ACO14216.1    AABR07021629    NEDP02000661    OWF55446.1    GL440813    EFN65399.1    KQ414663    KOC65507.1    JP014371    AES02969.1    KQ981864    KYN34244.1    AC105161    AK133221    AK144915    CH466520    BAE21565.1    BAE26132.1    EDL39255.1    GAMT01001410    GAMT01001409    GAMT01001408    GAMT01001407    GAMT01001406    GAMT01001405    GAMT01001404    GAMT01001403    GAMS01001375    GAMS01001372    GAMS01001371    GAMS01001370    GAMS01001369    GAMS01001368    GAMR01002945    GAMR01002944    GAMR01002943    GAMR01002942    GAMR01002941    GAMR01002940    GAMR01002939    GAMQ01003950    GAMQ01003949    GAMP01002079    GAMP01002078    GAMP01002077    GAMP01002076    GAMP01002075    JAB10451.1    JAB21761.1    JAB30987.1    JAB37901.1    JAB50676.1    AAGJ04096940    ADFV01184505    ADFV01184506    ADFV01184507    ADFV01184508    ADFV01184509    ADFV01184510    ADFV01184511    ADFV01184512    ADFV01184513    ADFV01184514    BC060314    AAH60314.1    AF202048    HAAF01000294    CCP72120.1    AFYH01047035    AFYH01047036    AFYH01047037    AFYH01047038    AFYH01047039    AFYH01047040    AFYH01047041    AFYH01047042    AFYH01047043    AFYH01047044    AAEX03005219    AAKN02037427    AAKN02037428    AAKN02037429    AAKN02037430    AAKN02037431    AAKN02037432    AACZ04056276    AACZ04056277    AACZ04056278    GABC01000518    GABF01007119    GABD01000341    NBAG03000285    JAA10820.1    JAA15026.1    JAA32759.1    PNI48222.1    ACTA01112981    ACTA01120981    ACTA01128981    ACTA01136981    ACTA01144980    ACTA01152979    ACTA01160978    ACTA01168976    ACTA01176974    ACTA01184972    AF202049    NDHI03003587    PNJ17889.1    CABD030007185    CABD030007186    CABD030007187    CABD030007188    CABD030007189    CABD030007190    CABD030007191    AJFE02086946    AJFE02086947    AF153191    AK094513    AK290701    AL031726    Z99758    AL356852    CH471067    BC006983    JL616087    AEH58294.1    AANG04002195    CCKQ01004544    CDW75698.1    AEMK02000022    GEBF01005558    JAN98074.1    AGTP01015068    AGTP01015069    AERX01011543    AERX01011544    AAGW02007052   

Proteomes

UP000218220    UP000007151    UP000053268    UP000053105    UP000242457    UP000005203    + More
UP000008144    UP000053097    UP000235965    UP000225706    UP000075809    UP000081671    UP000007755    UP000005205    UP000014760    UP000027135    UP000248480    UP000001593    UP000233140    UP000028761    UP000007648    UP000008237    UP000007646    UP000265140    UP000233180    UP000233080    UP000001038    UP000029965    UP000233120    UP000233100    UP000006718    UP000233060    UP000076502    UP000002494    UP000242188    UP000000311    UP000265180    UP000261680    UP000007875    UP000053825    UP000078541    UP000000589    UP000233220    UP000245341    UP000007110    UP000018467    UP000001073    UP000008225    UP000233040    UP000265200    UP000008672    UP000002254    UP000005447    UP000002277    UP000008912    UP000001519    UP000240080    UP000005640    UP000265100    UP000291021    UP000002281    UP000011712    UP000265160    UP000261360    UP000008227    UP000005215    UP000005207    UP000248482    UP000002280    UP000248484    UP000252040    UP000001811   

PRIDE

F1LNL9    Q9QXL8    Q9QXL7    Q9Y5B8   

Pfam

PF00334   NDK        + More
PF06565   DUF1126

Interpro

IPR001564   Nucleoside_diP_kinase        + More
IPR034907   NDK-like_dom       
IPR037993   NDPk7B       
IPR011410   NDPK7       
IPR036850   NDK-like_dom_sf       
IPR006602   Uncharacterised_DM10       
IPR010554   DUF1126       
IPR035525   NDPk7A       
IPR023005   Nucleoside_diP_kinase_AS       

SUPFAM

SSF54919   SSF54919       

Gene 3D

3.30.70.141    

CDD

cd04412  NDPk7B
cd04415  NDPk7A

ProteinModelPortal

A0A2W1BTV9   A0A2A4JZY2   A0A2H1X336   A0A212F1W4   A0A194PNE6   A0A0N1ITX7   + More
A0A2A3E3V5   A0A087ZWW7   C4B8X0   A0A1B6FBE1   A0A026VWD2   E9J644   A0A1B6LER2   A0A1B6KTD4   A0A2J7QC66   A0A2B4S5Z9   A0A2J7QC52   A0A2J7QC53   A0A151XC28   A0A1S3F4U5   F4X6X1   A0A158NFY0   J9HLV5   R7TZK1   A0A067RKK2   A0A2Y9RKT2   A0A1B6C8C7   A0A0C9QCH4   A7SP47   K9IJ52   A0A2K5ZQK5   A0A096N6Q5   G3VTT6   G7MFA1   E2BWD1   G3TAM2   A0A3P8ZQL6   A0A2K6LGL2   A0A2K5IWR3   Q05BM9   H2MLS7   A0A0D9RF97   A0A2K6BTG8   A0A2K5X5S7   H9FTL1   A0A2K5LKL9   Q80UP4   A0A154P1Y2   C1BYW3   F1LNL9   A0A210R3D6   E2AMH5   A0A3P9LEE9   A0A384CI25   H2ZR10   A0A0L7R3P5   G9KDJ4   A0A195F2D0   Q3UMG6   A0A2K6UUV2   U3E823   A0A2U3Y894   W4Z1L5   W5KX55   G1RY63   Q6PAG9   Q9QXL8   A0A3P8XTR1   F7GQ16   U6CNG2   A0A2K5PVF6   A0A3P9I4A5   H3B3B9   F1PMF2   H0V2N4   H2Q0K0   G1LYF0   Q9QXL7   A0A2J8SAT5   A0A2I2YP06   A0A2R9BXY8   Q9Y5B8   A0A3P8R4P9   A0A384CI35   K9K275   M3WB88   A0A3P9BMP9   A0A3B4XQE1   A0A078A2E8   A0A287AHH1   A0A0P6J402   I3MHE9   I3KT89   A0A2Y9JT67   F6Q3R3   A0A2Y9S527   A0A341B947   G1TFZ9  

PDB

3ZTS     E-value=1.06565e-16,     Score=212

KEGG

101737075    K00940 nucleoside-diphosphate kinase [EC:2.7.4.6] | (RefSeq) nucleoside diphosphate kinase 7

PATHWAY

00230    Purine metabolism - Bombyx mori (domestic silkworm)
00240    Pyrimidine metabolism - Bombyx mori (domestic silkworm)
00983    Drug metabolism - other enzymes - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0006228   GO:0006241   GO:0004550   GO:0005524   GO:0006183   GO:0005813   GO:1990830   GO:0007368   GO:0042073   GO:0060972   GO:0007420   GO:0046872   GO:0003351   GO:0036064   GO:0060830   GO:0005829   GO:0006165   GO:0030286   GO:0005216   GO:0045211   GO:0006281   GO:0048384  

PANTHER

PTHR43109  

Length:

381

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.36941

Exp number, first 60 AAs:

0.09001

Total prob of N-in:

0.03505

outside

1  -  381

 

 

Pi

69.108856

Theta

154.606781

Tajima's D

-1.763189

CLR

244.97495

CSRT

0.0300484975751212

Interpretation

Uncertain