Gene

KWMTBOMO02807  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA003688

Annotation

poly(U)-specific_endoribonuclease_homolog_precursor_[Papilio_xuthus]

Location

Bomo_Chr5(-):11790847-11794737      View in EpiBrowser

Full name

Poly(U)-specific endoribonuclease homolog      

Alternative Name

Protein endoU
Uridylate-specific endoribonuclease homolog

Location in the cell

Cytoplasmic   Reliability : 1.054 Extracellular   Reliability : 1.272 PlasmaMembrane   Reliability : 1.182

CDS

ATGAAAATTACATTGATTTTCGTTGTTTTTCTGGGGGTATGTCACGCTGATGACATAGCCCAGGCTGCGGGCCAGATCTTCAACAACATCCTTCCCAACTTGATTAGCAATCATGTGACTGGTCAGCAAGGGAACACAGCTCAAAACACTTTCCAGCAAATAGGCACAGTTGTCGGTGGCGTCGTTGACTATGCGAAGAAGAAGAGCTACGAAGATTTGTTGCGCCAAGCACAAGATTCGACGACCGACGATGACCTCCTCAGAGTTAGCGAGGAAATGTTTAATGCAGATATAAATAATGCCTTCAACTACATTCAAGTGAATTTACAAGGCAAGACCACTCCTATGTCTAGGAATGATGAAGCACAATCGAATTTATTAAACGTTCCTGAGAATGTATGGAGCGGACCAACAATAAGACCTTTTGTTGCACTATTCGACAACTATCACAAGAATGTGATCAGACCAGAGTTTGTTACGCCGAATGAAGAAACGGAACAAACCACTTACATCAACACTATTCTTGCTACGGGACCCATCAGGAGCCTCATTACTTTCTTAGTCAACAAAGGCATTACTCAGCTGAATGAGTATCCCGAACAAGTTGAGCTGCTGAGAAAGATTTGGTTCACGAAGTACGCACGCCACTGGACCGGCCTTTGCAAATGCAGTTGCGCCTTCGAGAACGTGTTTATGGCTGAACTCAAATCTAATGAGGTTCTAGGTCTTCACAGCTGGTTGTTCTTCGCTAAACGTGAATTAGATCACAAAGCCAACTACTTGGGTTACATCGACAAGCTGGATCTTAGTGGCAAAGGACTGATCCTCAAGCAGCACTCGGTGTTGAGCGAAACGAAAGACGCGCCCGAAGTGAACATGTTTGTTGGCACCTCCCCCGAACTGGAGACCGCTCTGTACACGCTCTGTTTCATGACCCGCCCGGACAGACCTTGCAGACTGCGCTTCAACAACATACCCTTCACTATCCAAACAAAATCGATCAAAGTCGAAAACTTACCGGTCATTGACACCGCTTACCCAACTTGGTAA

Protein

MKITLIFVVFLGVCHADDIAQAAGQIFNNILPNLISNHVTGQQGNTAQNTFQQIGTVVGGVVDYAKKKSYEDLLRQAQDSTTDDDLLRVSEEMFNADINNAFNYIQVNLQGKTTPMSRNDEAQSNLLNVPENVWSGPTIRPFVALFDNYHKNVIRPEFVTPNEETEQTTYINTILATGPIRSLITFLVNKGITQLNEYPEQVELLRKIWFTKYARHWTGLCKCSCAFENVFMAELKSNEVLGLHSWLFFAKRELDHKANYLGYIDKLDLSGKGLILKQHSVLSETKDAPEVNMFVGTSPELETALYTLCFMTRPDRPCRLRFNNIPFTIQTKSIKVENLPVIDTAYPTW

Description

Endoribonuclease.

Cofactor

Mn(2+)

Subunit

Monomer.

Similarity

Belongs to the MCM family.
Belongs to the ENDOU family.

Keywords

Complete proteome   Endonuclease   Hydrolase   Manganese   Metal-binding   Nuclease   Reference proteome   RNA-binding   Secreted   Signal  

Feature

chain  Poly(U)-specific endoribonuclease homolog

Uniprot

H9J2F1   I4DJA4   A0A194QTV9   I4DRJ0   A0A1E1WU27   S4PT37   + More
A0A346M341   A0A212EYN8   A0A2W1BNJ5   F6IA34   A0A2A4JUT1   A0A075F7E0   A0A0L7LH27   A0A2H1V3N0   Q5MGG7   A0A2P8Z2R2   S4P3D5   I4DRI3   A0A0J7MSF7   A0A067QX30   A0A2W1BPF9   A0A194PPM0   A0A194QUU4   U4UIW8   A0A0M9A6J8   A0A1E1WJY3   A0A3L8D6C2   E9IR65   A0A026VYP5   D6WSA3   A0A232FAE3   K7IX48   N6TQT1   E2BWC0   A0A1B6CSC7   A0A0M9A8U6   H9J1X0   A0A2A4JV71   A0A2A4JVG1   A0A1B6HJW4   E2APY1   A0A1B6FV66   A0A1W6EVV9   E2BWB9   A0A336L5G4   V9IK64   A0A2A3EE37   A0A0C9R987   A0A1J1HRH3   A0A0C9RCR6   K7IUV7   A0A1Y1LQD3   A0A1A9XBT6   A0A232F9E1   A0A0T6B131   A0A088AM29   A0A232FJB6   A0A0L7RIF8   K7IWD0   A0A1B0BDZ2   D3TQ61   A0A088AQF2   A0A1A9VCK9   A0A2A3ECX8   A0A0C9QL97   A0A1B0FRI4   A0A1A9ZEJ9   E9GW08   U5EP18   A0A1I8PMP8   A0A1I8PMU6   A0A1W4V1D5   B4R2P9   A0A154P629   A0A2M4BLL3   A0A182VRQ6   T1PE22   A0A2M4BJW7   B3MQP8   A0A1A9WT30   A0A182QLB6   A0A2M4DP21   B4H4U2   T1E7J1   A0A2M4ABY0   A0A2M4AC62   A0A182F7B5   A0A220XIQ8   B4MSH8   A0A1I8M0F7   A0A0M3QZI8   X2JJD6   Q9VZ49   B3NVC5   Q29I02   A0A182XV19   A0A182RVA7   A0A182TY62  

EC Number

3.1.-.-

Pubmed

19121390    22651552    26354079    23622113    22118469    28756777    + More
24662467    26227816    16023793    29403074    24845553    23537049    30249741    21282665    24508170    18362917    19820115    28648823    20075255    20798317    28004739    20353571    26951652    21292972    17994087    25315136    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    12537569    15632085    25244985   

EMBL

BABH01007795    AK401372    KQ459597    BAM17994.1    KPI94925.1    KQ461150    + More
KPJ08749.1    AK405138    BAM20530.1    GDQN01000580    JAT90474.1    GAIX01012718    JAA79842.1    MG844422    AXQ05185.1    AGBW02011460    OWR46613.1    KZ150007    PZC75195.1    FR751090    CBY85302.1    NWSH01000604    PCG75384.1    KJ544881    AIE56154.1    JTDY01001145    KOB74742.1    ODYU01000355    SOQ34972.1    AY829819    AAV91433.1    PYGN01000223    PSN50777.1    GAIX01006489    JAA86071.1    AK405130    BAM20523.1    LBMM01019810    KMQ83445.1    KK853256    KDR09265.1    PZC75197.1    KPI94923.1    KPJ08750.1    KB632322    ERL92343.1    KQ435726    KOX78257.1    GDQN01003725    JAT87329.1    QOIP01000012    RLU15786.1    GL765088    EFZ16938.1    KK107565    EZA48923.1    KQ971354    EFA05915.2    NNAY01000601    OXU27450.1    AAZX01000600    APGK01058327    KB741288    ENN70666.1    GL451103    EFN80024.1    GEDC01020872    JAS16426.1    KOX78239.1    BABH01007796    BABH01007797    BABH01007798    PCG75383.1    PCG75382.1    GECU01032712    GECU01015858    JAS74994.1    JAS91848.1    GL441630    EFN64513.1    GECZ01015715    JAS54054.1    KY563451    ARK19860.1    EFN80023.1    UFQS01001083    UFQT01001083    SSX08890.1    SSX28801.1    JR049187    AEY60891.1    KZ288282    PBC29552.1    GBYB01004695    JAG74462.1    CVRI01000016    CRK90130.1    GBYB01004696    JAG74463.1    AAZX01008132    GEZM01049779    GEZM01049778    JAV75853.1    NNAY01000634    OXU27285.1    LJIG01016277    KRT81084.1    NNAY01000115    OXU30836.1    KQ414584    KOC70614.1    JXJN01012729    EZ423563    ADD19839.1    KU513387    AMQ13201.1    KZ288293    PBC29016.1    GBYB01004299    JAG74066.1    CCAG010017603    GL732569    EFX76267.1    GANO01003858    JAB56013.1    CM000366    EDX17598.1    KQ434825    KZC07379.1    GGFJ01004781    MBW53922.1    KA646954    AFP61583.1    GGFJ01004225    MBW53366.1    CH902621    EDV44674.2    AXCN02000015    GGFL01015139    MBW79317.1    CH479209    EDW32704.1    GAMD01002997    JAA98593.1    GGFK01004948    MBW38269.1    GGFK01004991    MBW38312.1    MF278691    ASL04997.1    CH963851    EDW75067.1    CP012528    ALC49493.1    AE014298    AHN59572.1    BT031314    AY075327    CH954180    EDV46113.1    CH379064    EAL31604.3   

Proteomes

UP000005204    UP000053268    UP000053240    UP000007151    UP000218220    UP000037510    + More
UP000245037    UP000036403    UP000027135    UP000030742    UP000053105    UP000279307    UP000053097    UP000007266    UP000215335    UP000002358    UP000019118    UP000008237    UP000000311    UP000242457    UP000183832    UP000092443    UP000005203    UP000053825    UP000092460    UP000078200    UP000092444    UP000092445    UP000000305    UP000095300    UP000192221    UP000000304    UP000076502    UP000075920    UP000007801    UP000091820    UP000075886    UP000008744    UP000069272    UP000007798    UP000095301    UP000092553    UP000000803    UP000008711    UP000001819    UP000076408    UP000075900    UP000075902   

PRIDE

H9J2F1    H9J1X0    X2JJD6    Q9VZ49   

Pfam

PF09412   XendoU        + More
PF05761   5_nucleotid
PF17207   MCM_OB
PF00493   MCM
PF17855   MCM_lid

Interpro

IPR018998   EndoU_C        + More
IPR039787   ENDOU       
IPR037227   EndoU-like       
IPR008380   HAD-SF_hydro_IG_5-nucl       
IPR023214   HAD_sf       
IPR036412   HAD-like_sf       
IPR018525   MCM_CS       
IPR027417   P-loop_NTPase       
IPR033762   MCM_OB       
IPR041562   MCM_lid       
IPR001208   MCM_dom       
IPR003593   AAA+_ATPase       
IPR031327   MCM       
IPR012340   NA-bd_OB-fold       

SUPFAM

SSF142877   SSF142877        + More
SSF56784   SSF56784       
SSF52540   SSF52540       
SSF50249   SSF50249       

Gene 3D

3.40.50.1000    

ProteinModelPortal

H9J2F1   I4DJA4   A0A194QTV9   I4DRJ0   A0A1E1WU27   S4PT37   + More
A0A346M341   A0A212EYN8   A0A2W1BNJ5   F6IA34   A0A2A4JUT1   A0A075F7E0   A0A0L7LH27   A0A2H1V3N0   Q5MGG7   A0A2P8Z2R2   S4P3D5   I4DRI3   A0A0J7MSF7   A0A067QX30   A0A2W1BPF9   A0A194PPM0   A0A194QUU4   U4UIW8   A0A0M9A6J8   A0A1E1WJY3   A0A3L8D6C2   E9IR65   A0A026VYP5   D6WSA3   A0A232FAE3   K7IX48   N6TQT1   E2BWC0   A0A1B6CSC7   A0A0M9A8U6   H9J1X0   A0A2A4JV71   A0A2A4JVG1   A0A1B6HJW4   E2APY1   A0A1B6FV66   A0A1W6EVV9   E2BWB9   A0A336L5G4   V9IK64   A0A2A3EE37   A0A0C9R987   A0A1J1HRH3   A0A0C9RCR6   K7IUV7   A0A1Y1LQD3   A0A1A9XBT6   A0A232F9E1   A0A0T6B131   A0A088AM29   A0A232FJB6   A0A0L7RIF8   K7IWD0   A0A1B0BDZ2   D3TQ61   A0A088AQF2   A0A1A9VCK9   A0A2A3ECX8   A0A0C9QL97   A0A1B0FRI4   A0A1A9ZEJ9   E9GW08   U5EP18   A0A1I8PMP8   A0A1I8PMU6   A0A1W4V1D5   B4R2P9   A0A154P629   A0A2M4BLL3   A0A182VRQ6   T1PE22   A0A2M4BJW7   B3MQP8   A0A1A9WT30   A0A182QLB6   A0A2M4DP21   B4H4U2   T1E7J1   A0A2M4ABY0   A0A2M4AC62   A0A182F7B5   A0A220XIQ8   B4MSH8   A0A1I8M0F7   A0A0M3QZI8   X2JJD6   Q9VZ49   B3NVC5   Q29I02   A0A182XV19   A0A182RVA7   A0A182TY62  

PDB

2C1W     E-value=6.97784e-18,     Score=222

KEGG

101740108    K14648 poly(U)-specific endoribonuclease [EC:3.1.-.-] | (RefSeq) poly(U)-specific endoribonuclease h

GO

GO:0004521   GO:0008233   GO:0006270   GO:0003677   GO:0005524   GO:0090502   GO:0046872   GO:0003723   GO:0005576   GO:0016788   GO:0006260   GO:0003777   GO:0007018   GO:0030286   GO:0005216   GO:0045211   GO:0006281   GO:0048384  

PANTHER

PTHR12439   PTHR12103   PTHR11630  

Subcellular location

Secreted  

SignalP

Position:   1 - 16,         Likelihood:  0.999406

 

 

Length:

349

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.347930000000001

Exp number, first 60 AAs:

0.34365

Total prob of N-in:

0.02059

outside

1  -  349

 

 

Pi

35.987912

Theta

31.295337

Tajima's D

0.510591

CLR

2.8401

CSRT

0.52392380380981

Interpretation

Uncertain