Gene

KWMTBOMO02787

Pre Gene Modal

BGIBMGA003697

Annotation

PREDICTED:_semaphorin-1A-like_[Amyelois_transitella]

Location

Bomo_Chr5(-):10769062-10783539      View in EpiBrowser

Full name

Semaphorin-1A      

Alternative Name

Fasciclin IV
Fasciclin-4
Semaphorin-I

Location in the cell

Extracellular   Reliability : 1.719 Nuclear   Reliability : 1.185

CDS

ATGGCCGTCGCTCGCGCGGTCCTAGTATTGTTAGCGTCCACTGCACAGGCGTGGATGCCCGACTCAAACGCACGAATCCACGTGAAATACGGCGATGAAAATTCAGAACAGTTCGTGGGTAATGCAACGGCACCGGACCATTTCCGAATTTTAGACAGAGACGACTTCTCTATTATAGTTGGTGGCAGGAATACTGTCTACAATCTCAGTCTCTACGATCTGTCAGAAAACGTTGATCAGCGCTTAGAGTGGCAATCGACAGAAGCACATAAAGAGTTATGTCAGCTAAAAGGAAAATCTCCAGATGAATGTCAAAATTATCCCCGGATTGCTGTGCGAGCGCACGGCCGCTTCCTCGTTTGTGGCACGAACGCTTTCAAACCACAATGCAGGCGCTATGGAAGACATCCCCCTTACCGTCATATCGATGAATTTGATGGGAGTGGCCGATGTCCGTATGATCCTCAGCACAATTCGACTTCTGTTTTTGTCGATGGGCAACTCTATACGGCCACGGCAGCGGATTTCTCGGGCACTGATCCACTAATTTATCGCGAGCCAGTAAGGACAGGACGGTCAGATCTCTTGTTATTAAATGACCCGTCATTTGTTGGATCGGTTGCTTCCACCAGTCATGCTTATTTCTTCTACAGAGAAACCGCAGTGGAATACATGAATTGTGGAAAGGCTGTTTATTCAAGAGTTGCAAGAATATGTCTTAACGACAAAGGAGGCCCGAATCGATATAGCGATCAATGGATGTCATTTCTCAAAGCCCGTATGAACTGTTCAATGCCTGGAGACTATCCTTTCTATTTTGACGAAATTCAAGCTACAACAGAACTTATAAATGGTATATATGGCAGTGGTAACAGTCGAAATGACATAATGTACGCAGTATTCACGACACCGCAAAACGCAATCGGCGGATCAGCGGTATGTGCATTTGCAATGAGAGATATTATAGATGCTTTTGAGGGACTCTTCAAAGGACAAGAAAATTGGAACTCAAATTGGCTGCCCGTTAAAAAAGAGAAAATACCTCAAACCAGGCCCGGTTCTTGCGTGGAGGACAGTAGGACTCTTTCCGATGAAGTCGTTAACTTCGTAAAGGCCCATCCTTTGATGGATAAAGCGGTACCGTCGTTTTTAGCACGACCTATACTGATTAGAGTCAGTCTGCAATACAGATTTTCCGCTATTGCCGTTCATCCTCAAGTTCAAGCAATGAATGGAAACAAATACGATGTATTGTACATCGGCACTGACGATGGTAGAGTCATCAAAGCTGTTAATGTTGCCTCTAACGAAGGCGTTTTTGACGCGAGCGTAGATGAGTATAGCAAAAATCCTGTGAGGACCGCAGTCATTTCTGAAGAACAGGTTCTGCCTCAAGGTGTACCTATCAAACAGATGCACGTTGCTCTGACCACTGAAAAATTGATAGTGGCTTCGGGTGATATTATTAAAGCTGTAACATTATCTCACTGCGGGAACGTGCAATCGTGCAGAGAATGCGTTTCATTACAAGATCCACACTGCGCTTGGGACTCCAAGGAACAACAATGTTCATGGGTTGGGAACAGACAATTTCCGAATCCTGAGAGATTCTTACAAAATGTAGAACATGGAAAGACTGATATTTGTAATAAGCTCCCCGCTCTGTTACCGGGTGAACGACATAGCAACAGAAATCCTGGAACTAAAAAACCTTCCTCCTCCGAATCCGAAGCACGACAAAAGACTGATGACATTCAAAATGAAATTTTTATAGAAGAAGTTTTAGAAACAAACGTTATAGCGGAAGAGAAAAATTCACACAACAATAAACACGAAACCGATTTGCTGACAGTAGAAGCAGCCGATGGGAATATTTATAGTGCACAAGCGCTCTTCACAGCCGTAGTGGCGTCTTGTCTCGTTACCCTCATGGTTGGGTTTGTCTTCGGATATCTATTTTCGCGCCGATTTCGACACCCATTTTTTTCCGATTCCCCACCTTTTAATGAACAACACAATCATTTAAATAGATTAAGTCCATTAGAAACTCCATTAAACGCAAACTCTGCGTATCTCCCACCTCGATCAAAAAACGTCAATATGGTAGCGAACGTCTGCCCTCTGGCAAAACAAGACAACTTGCACCTGGAGCTCGGCAAAGAGCGGACTCTAGATTTACGAAATTCCACCGAATCCCTGGATAAAGATCTCAAGTGCGGCACTTTACAAAAAGTGAAAAAAACATACATATGA

Protein

MAVARAVLVLLASTAQAWMPDSNARIHVKYGDENSEQFVGNATAPDHFRILDRDDFSIIVGGRNTVYNLSLYDLSENVDQRLEWQSTEAHKELCQLKGKSPDECQNYPRIAVRAHGRFLVCGTNAFKPQCRRYGRHPPYRHIDEFDGSGRCPYDPQHNSTSVFVDGQLYTATAADFSGTDPLIYREPVRTGRSDLLLLNDPSFVGSVASTSHAYFFYRETAVEYMNCGKAVYSRVARICLNDKGGPNRYSDQWMSFLKARMNCSMPGDYPFYFDEIQATTELINGIYGSGNSRNDIMYAVFTTPQNAIGGSAVCAFAMRDIIDAFEGLFKGQENWNSNWLPVKKEKIPQTRPGSCVEDSRTLSDEVVNFVKAHPLMDKAVPSFLARPILIRVSLQYRFSAIAVHPQVQAMNGNKYDVLYIGTDDGRVIKAVNVASNEGVFDASVDEYSKNPVRTAVISEEQVLPQGVPIKQMHVALTTEKLIVASGDIIKAVTLSHCGNVQSCRECVSLQDPHCAWDSKEQQCSWVGNRQFPNPERFLQNVEHGKTDICNKLPALLPGERHSNRNPGTKKPSSSESEARQKTDDIQNEIFIEEVLETNVIAEEKNSHNNKHETDLLTVEAADGNIYSAQALFTAVVASCLVTLMVGFVFGYLFSRRFRHPFFSDSPPFNEQHNHLNRLSPLETPLNANSAYLPPRSKNVNMVANVCPLAKQDNLHLELGKERTLDLRNSTESLDKDLKCGTLQKVKKTYI

Similarity

Belongs to the semaphorin family.

Keywords

Developmental protein   Differentiation   Direct protein sequencing   Disulfide bond   Glycoprotein   Membrane   Neurogenesis   Signal   Transmembrane   Transmembrane helix  

Feature

chain  Semaphorin-1A

Uniprot

A0A1E1WC97   A0A2A4JYC6   H9J2G0   A0A2H1VS45   A0A194PNL3   A0A194QQJ3   + More
A0A212ET69   Q26473   D6W6W2   A0A1Y1K0L5   A0A1W4X637   A0A1B6DFY7   A0A3L8DM92   A0A336MG78   A0A2J7QS28   E0VBJ1   Q26972   A0A2J7QS11   Q0IG92   A0A2J7QS30   A0A1S4F3R5   A0A0C9R8D1   A0A232FMU3   A0A182RS11   A0A1B6FGB8   A0A1B6H2H2   A0A182YPJ8   A0A1Q3FJ32   A0A182JFL9   A0A1B6EFF5   A0A158NUH6   A0A182QP35   A0A0A9XEK4   W5J663   A0A023EXT7   A0A182FFG8   B0VZ58   A0A0A9Y8X2   A0A182WKW9   A0A182P8Q5   A0A182TM43   A0A182NJT2   A0A182HWJ8   A0A182LWZ4   A0A023F124   A0A182L334   A0A0P6FR96   A0A0P5ZGF1   A0A224X817   T1IUH4   A0A0P5D998   A0A195BSG6   A0A0C9RBM9   A0A195FWU0   T1HSF9   Q7Q6P3   A0A182XMP0   A0A151WG11   A0A0P5PK83   A0A084WJK2   A0A0P5ZCN6   D6WSR6   A0A139WF26   A0A1Y1KUY7   A0A0P5SU30   A0A1Y1KYH7   A0A1Y1KXI4   A0A1Y1KV12   A0A0N8A7A2   A0A1B6LRG7   A0A2Z5H001   S6CVV9   E9HEJ9   A7UTV5   A0A0P4W2V3   K7ITI6   A0A182VHK3   U5ETI2   A0A0K8VV80   K7J8B0   B4MRZ5   A0A0L7RB67   E2BXZ6   A0A0K8WH01   B4GIA8   A0A0P5C540   T1JEM8   A0A1I8QBQ1   Q28Z44   A0A0P4YG15   A0A0K8WDN8   A0A088A2N7   A0A0A1WTV7   A0A0K8W6X1   J9JWK6   A0A0P6DEJ5   A0A0P5ZX68  

Pubmed

19121390    26354079    22118469    1418998    18362917    19820115    + More
28004739    30249741    20566863    8269517    17510324    28648823    25244985    21347285    25401762    20920257    23761445    24945155    25474469    20966253    12364791    24438588    29995882    23938757    21292972    20075255    17994087    20798317    15632085    23185243    25830018   

EMBL

GDQN01006440    JAT84614.1    NWSH01000438    PCG76430.1    BABH01007915    ODYU01003919    + More
SOQ43282.1    KQ459597    KPI94907.1    KQ461181    KPJ07619.1    AGBW02012631    OWR44680.1    L00709    KQ971307    EFA11605.1    GEZM01096218    JAV55044.1    GEDC01012742    JAS24556.1    QOIP01000006    RLU21527.1    UFQS01001159    UFQT01001159    SSX09294.1    SSX29196.1    NEVH01011881    PNF31377.1    DS235031    EEB10747.1    L26080    PNF31378.1    CH477261    EAT45665.1    PNF31376.1    GBYB01004280    JAG74047.1    NNAY01000025    OXU31839.1    GECZ01020756    JAS49013.1    GECZ01000949    JAS68820.1    GFDL01007404    JAV27641.1    GEDC01000668    JAS36630.1    ADTU01026425    ADTU01026426    ADTU01026427    ADTU01026428    ADTU01026429    ADTU01026430    ADTU01026431    ADTU01026432    ADTU01026433    ADTU01026434    AXCN02000522    GBHO01025528    GBRD01000453    JAG18076.1    JAG65368.1    ADMH02002078    ETN59476.1    GAPW01000264    JAC13334.1    DS231813    EDS25650.1    GBHO01014082    JAG29522.1    APCN01001496    AXCM01001737    AXCM01001738    GBBI01003527    JAC15185.1    GDIQ01044358    JAN50379.1    GDIP01045697    JAM58018.1    GFTR01007930    JAW08496.1    JH431535    GDIP01175520    JAJ47882.1    KQ976417    KYM89960.1    GBYB01004281    JAG74048.1    KQ981193    KYN45125.1    ACPB03022318    ACPB03022319    AAAB01008960    EAA10953.4    KQ983203    KYQ46773.1    GDIQ01148670    JAL03056.1    ATLV01024037    KE525348    KFB50396.1    GDIP01045698    JAM58017.1    KQ971354    EFA07551.2    KYB26553.1    GEZM01073256    JAV65223.1    GDIP01135624    JAL68090.1    GEZM01073259    JAV65220.1    GEZM01073258    JAV65221.1    GEZM01073257    JAV65222.1    GDIP01175521    JAJ47881.1    GEBQ01013725    JAT26252.1    MF817714    AXC32911.1    HF586479    CCQ71364.1    GL732629    EFX69865.1    EDO63729.1    GDRN01107544    JAI57404.1    AAZX01003331    AAZX01006471    AAZX01008279    GANO01002767    JAB57104.1    GDHF01009527    JAI42787.1    AAZX01003470    AAZX01003475    CH963850    EDW74884.2    KQ414617    KOC68114.1    GL451363    EFN79430.1    GDHF01027673    GDHF01001886    JAI24641.1    JAI50428.1    CH479183    EDW36228.1    GDIP01175523    JAJ47879.1    JH432127    CM000071    EAL25771.2    KRT02534.1    GDIP01229117    JAI94284.1    GDHF01003140    GDHF01000015    JAI49174.1    JAI52299.1    GBXI01011783    JAD02509.1    GDHF01028577    GDHF01005530    JAI23737.1    JAI46784.1    ABLF02034510    ABLF02034514    ABLF02034515    ABLF02034517    ABLF02034518    GDIQ01087627    JAN07110.1    GDIP01050742    JAM52973.1   

Proteomes

UP000218220    UP000005204    UP000053268    UP000053240    UP000007151    UP000007266    + More
UP000192223    UP000279307    UP000235965    UP000009046    UP000008820    UP000215335    UP000075900    UP000076408    UP000075880    UP000005205    UP000075886    UP000000673    UP000069272    UP000002320    UP000075920    UP000075885    UP000075902    UP000075884    UP000075840    UP000075883    UP000075882    UP000078540    UP000078541    UP000015103    UP000007062    UP000076407    UP000075809    UP000030765    UP000000305    UP000002358    UP000075903    UP000007798    UP000053825    UP000008237    UP000008744    UP000095300    UP000001819    UP000005203    UP000007819   

PRIDE

H9J2G0   

Pfam

PF01403   Sema        + More
PF01437   PSI

Interpro

IPR001627   Semap_dom        + More
IPR042068   SEM1A_sema_dom       
IPR002165   Plexin_repeat       
IPR036352   Semap_dom_sf       
IPR015943   WD40/YVTN_repeat-like_dom_sf       
IPR027231   Semaphorin       
IPR016201   PSI       

SUPFAM

SSF101912   SSF101912       

Gene 3D

2.130.10.10    

CDD

cd11237  Sema_1A

ProteinModelPortal

A0A1E1WC97   A0A2A4JYC6   H9J2G0   A0A2H1VS45   A0A194PNL3   A0A194QQJ3   + More
A0A212ET69   Q26473   D6W6W2   A0A1Y1K0L5   A0A1W4X637   A0A1B6DFY7   A0A3L8DM92   A0A336MG78   A0A2J7QS28   E0VBJ1   Q26972   A0A2J7QS11   Q0IG92   A0A2J7QS30   A0A1S4F3R5   A0A0C9R8D1   A0A232FMU3   A0A182RS11   A0A1B6FGB8   A0A1B6H2H2   A0A182YPJ8   A0A1Q3FJ32   A0A182JFL9   A0A1B6EFF5   A0A158NUH6   A0A182QP35   A0A0A9XEK4   W5J663   A0A023EXT7   A0A182FFG8   B0VZ58   A0A0A9Y8X2   A0A182WKW9   A0A182P8Q5   A0A182TM43   A0A182NJT2   A0A182HWJ8   A0A182LWZ4   A0A023F124   A0A182L334   A0A0P6FR96   A0A0P5ZGF1   A0A224X817   T1IUH4   A0A0P5D998   A0A195BSG6   A0A0C9RBM9   A0A195FWU0   T1HSF9   Q7Q6P3   A0A182XMP0   A0A151WG11   A0A0P5PK83   A0A084WJK2   A0A0P5ZCN6   D6WSR6   A0A139WF26   A0A1Y1KUY7   A0A0P5SU30   A0A1Y1KYH7   A0A1Y1KXI4   A0A1Y1KV12   A0A0N8A7A2   A0A1B6LRG7   A0A2Z5H001   S6CVV9   E9HEJ9   A7UTV5   A0A0P4W2V3   K7ITI6   A0A182VHK3   U5ETI2   A0A0K8VV80   K7J8B0   B4MRZ5   A0A0L7RB67   E2BXZ6   A0A0K8WH01   B4GIA8   A0A0P5C540   T1JEM8   A0A1I8QBQ1   Q28Z44   A0A0P4YG15   A0A0K8WDN8   A0A088A2N7   A0A0A1WTV7   A0A0K8W6X1   J9JWK6   A0A0P6DEJ5   A0A0P5ZX68  

PDB

6FKN     E-value=9.66115e-144,     Score=1310

KEGG

101741638    K06842 semaphorin 6 | (RefSeq) semaphorin-1A-like

GO

GO:0016021   GO:0007399   GO:0030154   GO:0030335   GO:0045499   GO:0007411   GO:0001755   GO:0005615   GO:0030215   GO:0048843   GO:0050919   GO:0071526   GO:0016020   GO:0001700   GO:0005515   GO:0005789   GO:0006506   GO:0016740   GO:0004889   GO:0005216   GO:0045211   GO:0006281   GO:0048384  

PANTHER

PTHR11036  

Subcellular location

Membrane  

SignalP

Position:   1 - 17,         Likelihood:  0.965747

 

 

Length:

750

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

22.91414

Exp number, first 60 AAs:

0.12027

Total prob of N-in:

0.00876

outside

1  -  630

TMhelix

631  -  653

inside

654  -  750

 

 

Pi

222.623012

Theta

182.80734

Tajima's D

0.696386

CLR

0.157989

CSRT

0.573521323933803

Interpretation

Uncertain