Gene

KWMTBOMO02775  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA003493

Annotation

hypothetical_protein_KGM_01857_[Danaus_plexippus]

Location

Bomo_Chr5(+):10621801-10625892      View in EpiBrowser

Full name

Mediator of RNA polymerase II transcription subunit 20      

Alternative Name

Mediator complex subunit 20

Location in the cell

PlasmaMembrane   Reliability : 3.532

CDS

ATGGAGATTGAAATTCTGAGCGTATCTAGCGCGAAACCGCTCGGCAAGATTCACGTTACAGGTGAAAGTTCGATAAAGAATGTAAAAGAAAAAATCCAACAGAGCGTGAAGAAATCTCTATACCCAGATCGTCAGGCCCTCAAACTGGAGGCTAAAGGCAAAACGTTGAAAGATGAAGATACTCTGAATTCCCTTAATATTCAAGACGGATCCAAGCTTTTTTTAAAAGATCTTGGACCTCAAGTATCTTGGCGGAATGTGTTTTTAGCTGAATATGCTGGACCACTCTTTGTTTACTTGTGGGTGTATCAAAGACCGTGGATTTTATATGGTACACAAACGTCAAGTCCTGAGCAAGTAGCTACAGTTGCAGCAATATGTTGGTCAGCACACTATGCCAAAAGGTTGTTTGAAACTTTGTTCATTCATCGCTTTTCACATGGTACGATGCCATTGAAGAACTTGTTCAGAAACTGTGCATATTATTGGTTGTTTGCCCTCTATGTGGCTTATCATGTGAACCATCCCCTATACACTGCTCCCTGTACTACTTGTTACTACATAGGACTTGGAGGTTTTGTTCTTTGCGAATTAGGAAACCTGAGCATTCACATACTTTTGAAGAACCTTCGTCCGCCCGGCACGAAGATACGCCGCATTCCTAAACCGGACGGAAACCCCTTTTCTCTTCTTTTAAACTTCGTGTCTTGTCCCAACTATACATATGAGTTCGGATCTTGGCTATTTTTCACTATCATGACTAAATGTGCCCCAGCGGGTCTGTTCGCTGCGGCAGGCTTCTATCAGATGGCCGTTTGGGCCATCGGTAAACATCGCAACTACAAGAAGGAATTCCCAGACTACCCCAAAGGCCGTAAAGCTATTCTCCCATTCATTCTATAA

Protein

MEIEILSVSSAKPLGKIHVTGESSIKNVKEKIQQSVKKSLYPDRQALKLEAKGKTLKDEDTLNSLNIQDGSKLFLKDLGPQVSWRNVFLAEYAGPLFVYLWVYQRPWILYGTQTSSPEQVATVAAICWSAHYAKRLFETLFIHRFSHGTMPLKNLFRNCAYYWLFALYVAYHVNHPLYTAPCTTCYYIGLGGFVLCELGNLSIHILLKNLRPPGTKIRRIPKPDGNPFSLLLNFVSCPNYTYEFGSWLFFTIMTKCAPAGLFAAAGFYQMAVWAIGKHRNYKKEFPDYPKGRKAILPFIL

Description

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Subunit

Component of the Mediator complex.

Similarity

Belongs to the Mediator complex subunit 20 family.

Uniprot

H9J1V6   A0A2H1WLT5   A0A1E1WGZ1   A0A2A4JXZ9   A0A212ET74   A0A194QQ35   + More
A0A194PQ79   S4PKR4   A0A023EP11   A0A1S4FKB1   Q16XY3   A0A0L7LEE8   A0A2R7WSV0   A0A0A9YK63   A0A1B6LQF0   A0A2P8YYK5   A0A1B6D543   A0A1B6GJF8   A0A023F8K7   A0A224XU77   A0A069DYJ0   U5EW85   C4WUF0   A0A1B0CYT3   K7IQG4   R4FNG7   A0A0V0G545   A0A0P4VMW4   A0A2S2PME7   A0A067R6D5   A0A2M4AU39   A0A164N7Q9   A0A2M4BVN3   A0A1Q3FJM3   W5JKJ2   A0A1B0CRY0   B0WGJ0   A0A1L8DYD0   A0A3L8DSV6   E9GW93   A0A232F5Q4   A0A0P6JLI6   A0A182JFQ7   A0A182WE52   A0A088A633   A0A182RW82   A0A0P4YTJ9   V9IIH5   A0A2A3EKH2   E1ZVD6   A0A2M3ZIW9   A0A182LU68   A0A1J1J5G6   T1DL17   A0A182PM20   A0A182WXW9   A0A182VKY9   A0A1S4H4R2   A0A182I5Z0   A0A182KV24   A0A182K178   A0A0J7KGH9   E0VAG9   A0A226D9G8   Q7PRK1   A0A0L0CPP4   A0A182QAW7   A0A1L8DYB8   A0A0L7R1Z5   A0A0C9PKH4   A0A182FVF9   A0A195FCI3   A0A1L8DY76   A0A151X9J5   Q29EZ4   B4H5Q5   A0A1I8NAH1   A0A182N2N1   A0A0P4W5Z7   B4KXU2   D3TMN8   B4IZ30   A0A0A1X8V1   E2BC93   A0A0K8V599   A0A1A9Z6P5   A0A3B0JT05   A0A2J7R3M1   A0A3B0JXT9   A0A3B0JVZ5   A0A034W6Y8   A0A154P4C8   W8BW93   A0A023FVA3   A0A0K2TWN1   B3M7Z6   A0A023FIJ0   A0A1A9V5T0   B4MXT0   A0A1E1X7K7  

Pubmed

19121390    22118469    26354079    23622113    24945155    17510324    + More
26227816    25401762    26823975    29403074    25474469    26334808    20075255    27129103    24845553    20920257    23761445    30249741    21292972    28648823    20798317    12364791    20966253    20566863    26108605    15632085    17994087    25315136    20353571    25830018    25348373    24495485    28503490   

EMBL

BABH01007931    ODYU01009501    SOQ53988.1    GDQN01005740    GDQN01004826    GDQN01001379    + More
JAT85314.1    JAT86228.1    JAT89675.1    NWSH01000406    PCG76646.1    AGBW02012631    OWR44692.1    KQ461181    KPJ07607.1    KQ459597    KPI94894.1    GAIX01004360    JAA88200.1    GAPW01002903    JAC10695.1    CH477530    EAT39460.1    JTDY01001546    KOB73576.1    KK855455    PTY22642.1    GBHO01036753    GBHO01012121    GBRD01011606    GDHC01003754    JAG06851.1    JAG31483.1    JAG54218.1    JAQ14875.1    GEBQ01014031    JAT25946.1    PYGN01000284    PSN49327.1    GEDC01016501    JAS20797.1    GECZ01007187    JAS62582.1    GBBI01000991    JAC17721.1    GFTR01004773    JAW11653.1    GBGD01002305    JAC86584.1    GANO01001541    JAB58330.1    ABLF02020439    AK341037    BAH71520.1    AJVK01009337    AJVK01009338    ACPB03009595    GAHY01000578    JAA76932.1    GECL01002952    JAP03172.1    GDKW01000688    JAI55907.1    GGMR01017839    MBY30458.1    KK852921    KDR13798.1    GGFK01010911    MBW44232.1    LRGB01002864    KZS05714.1    GGFJ01007850    MBW56991.1    GFDL01007317    JAV27728.1    ADMH02001177    ETN63833.1    AJWK01025448    DS231926    EDS26987.1    GFDF01002626    JAV11458.1    QOIP01000004    RLU23507.1    GL732569    EFX76310.1    NNAY01000969    OXU25677.1    GDIQ01014905    JAN79832.1    GDIP01222746    JAJ00656.1    JR049116    AEY60865.1    KZ288229    PBC31679.1    GL434492    EFN74846.1    GGFM01007698    MBW28449.1    AXCM01007239    CVRI01000069    CRL07044.1    GAMD01000666    JAB00925.1    AAAB01008848    APCN01003537    LBMM01007908    KMQ89316.1    DS235006    EEB10375.1    LNIX01000028    OXA41790.1    EAA07072.2    JRES01000080    KNC34335.1    AXCN02001080    GFDF01002685    JAV11399.1    KQ414667    KOC64831.1    GBYB01001528    JAG71295.1    KQ981673    KYN38345.1    GFDF01002686    JAV11398.1    KQ982373    KYQ56990.1    CH379070    EAL29915.1    CH479211    EDW33107.1    GDRN01070305    JAI63901.1    CH933809    EDW17614.1    EZ422690    ADD18966.1    CH916366    EDV95552.1    GBXI01007184    JAD07108.1    GL447257    EFN86629.1    GDHF01018391    JAI33923.1    OUUW01000009    SPP85244.1    NEVH01007818    PNF35438.1    SPP85242.1    SPP85243.1    GAKP01007626    JAC51326.1    KQ434809    KZC06731.1    GAMC01003078    JAC03478.1    GBBL01001529    JAC25791.1    HACA01013018    CDW30379.1    CH902618    EDV39904.1    GBBK01003090    JAC21392.1    CH963876    EDW76849.1    GFAC01003946    JAT95242.1   

Proteomes

UP000005204    UP000218220    UP000007151    UP000053240    UP000053268    UP000008820    + More
UP000037510    UP000245037    UP000007819    UP000092462    UP000002358    UP000015103    UP000027135    UP000076858    UP000000673    UP000092461    UP000002320    UP000279307    UP000000305    UP000215335    UP000075880    UP000075920    UP000005203    UP000075900    UP000242457    UP000000311    UP000075883    UP000183832    UP000075885    UP000076407    UP000075903    UP000075840    UP000075882    UP000075881    UP000036403    UP000009046    UP000198287    UP000007062    UP000037069    UP000075886    UP000053825    UP000069272    UP000078541    UP000075809    UP000001819    UP000008744    UP000095301    UP000075884    UP000009192    UP000001070    UP000008237    UP000092445    UP000268350    UP000235965    UP000076502    UP000007801    UP000078200    UP000007798   

PRIDE

H9J1V6   

Pfam

PF02544   Steroid_dh        + More
PF00240   ubiquitin
PF08612   Med20
PF05652   DcpS
PF09814   HECT_2

Interpro

IPR000626   Ubiquitin_dom        + More
IPR001104   3-oxo-5_a-steroid_4-DH_C       
IPR039357   SRD5A/TECR       
IPR029071   Ubiquitin-like_domsf       
IPR013921   Mediator_Med20       
IPR008594   DcpS/DCS2       
IPR036265   HIT-like_sf       
IPR011145   Scavenger_mRNA_decap_enz_N       
IPR019193   UBQ-conj_enz_E2-bd_prot       

SUPFAM

SSF54236   SSF54236        + More
SSF54197   SSF54197       
SSF102860   SSF102860       

Gene 3D

3.30.428.10    

ProteinModelPortal

H9J1V6   A0A2H1WLT5   A0A1E1WGZ1   A0A2A4JXZ9   A0A212ET74   A0A194QQ35   + More
A0A194PQ79   S4PKR4   A0A023EP11   A0A1S4FKB1   Q16XY3   A0A0L7LEE8   A0A2R7WSV0   A0A0A9YK63   A0A1B6LQF0   A0A2P8YYK5   A0A1B6D543   A0A1B6GJF8   A0A023F8K7   A0A224XU77   A0A069DYJ0   U5EW85   C4WUF0   A0A1B0CYT3   K7IQG4   R4FNG7   A0A0V0G545   A0A0P4VMW4   A0A2S2PME7   A0A067R6D5   A0A2M4AU39   A0A164N7Q9   A0A2M4BVN3   A0A1Q3FJM3   W5JKJ2   A0A1B0CRY0   B0WGJ0   A0A1L8DYD0   A0A3L8DSV6   E9GW93   A0A232F5Q4   A0A0P6JLI6   A0A182JFQ7   A0A182WE52   A0A088A633   A0A182RW82   A0A0P4YTJ9   V9IIH5   A0A2A3EKH2   E1ZVD6   A0A2M3ZIW9   A0A182LU68   A0A1J1J5G6   T1DL17   A0A182PM20   A0A182WXW9   A0A182VKY9   A0A1S4H4R2   A0A182I5Z0   A0A182KV24   A0A182K178   A0A0J7KGH9   E0VAG9   A0A226D9G8   Q7PRK1   A0A0L0CPP4   A0A182QAW7   A0A1L8DYB8   A0A0L7R1Z5   A0A0C9PKH4   A0A182FVF9   A0A195FCI3   A0A1L8DY76   A0A151X9J5   Q29EZ4   B4H5Q5   A0A1I8NAH1   A0A182N2N1   A0A0P4W5Z7   B4KXU2   D3TMN8   B4IZ30   A0A0A1X8V1   E2BC93   A0A0K8V599   A0A1A9Z6P5   A0A3B0JT05   A0A2J7R3M1   A0A3B0JXT9   A0A3B0JVZ5   A0A034W6Y8   A0A154P4C8   W8BW93   A0A023FVA3   A0A0K2TWN1   B3M7Z6   A0A023FIJ0   A0A1A9V5T0   B4MXT0   A0A1E1X7K7  

PDB

2DZJ     E-value=4.43002e-05,     Score=110

KEGG

101742899    K10258 very-long-chain enoyl-CoA reductase [EC:1.3.1.93] | (RefSeq) probable very-long-chain enoyl-C

PATHWAY

00062    Fatty acid elongation - Bombyx mori (domestic silkworm)
01040    Biosynthesis of unsaturated fatty acids - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
01212    Fatty acid metabolism - Bombyx mori (domestic silkworm)

GO

GO:0016021   GO:0006629   GO:0016627   GO:0042761   GO:0016491   GO:0003712   GO:0016592   GO:0006357   GO:0016787   GO:0000290   GO:0005515   GO:0005737   GO:0004889   GO:0005216   GO:0045211   GO:0006281   GO:0048384  

PANTHER

PTHR10556  

Subcellular location

Nucleus  

Length:

300

Number of predicted TMHs:

3

Exp number of AAs in TMHs:

80.41283

Exp number, first 60 AAs:

0.00018

Total prob of N-in:

0.23554

outside

1  -  158

TMhelix

159  -  178

inside

179  -  184

TMhelix

185  -  207

outside

208  -  245

TMhelix

246  -  268

inside

269  -  300

 

 

Pi

205.417078

Theta

175.439705

Tajima's D

0.607367

CLR

0.070125

CSRT

0.543822808859557

Interpretation

Uncertain