Gene

KWMTBOMO02768  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA003490

Annotation

PREDICTED:_Golgi_phosphoprotein_3_homolog_rotini_[Amyelois_transitella]

Location

Bomo_Chr5(+):10446541-10450073      View in EpiBrowser

Full name

Golgi phosphoprotein 3 homolog sauron      

Alternative Name

Protein rotini

Location in the cell

Cytoplasmic   Reliability : 1.623 Nuclear   Reliability : 1.317

CDS

ATGAACCGTACTGAGGGTTTAGTGCAACGAAGAAATGTTATAAAGGAGAGTAACACAGACGGACAGAAAGAAAATCACGACAACGATGATAAGAAAAATGATAAAAATTATGATGACGGAGATTCCAAGGAAACTAAATTGACATTAATGGAAGAAGTGTTACTGTTAGGGTTAAAGGATAAAGAGGGTTATACATCATTTTGGAATGACTGCATATCCAGTGGTCTAAGAGGATGCATTCTAATTGAACTGGGCTTAAGAGGACGACTTGAACTGGAGCGAGCTGGAATGCGTAGGAAAGGCTTGTTGTCTAGAAAAGTGATTGTAAAGTCAGATACTTTAACCGGTGATGTTCTGCTAGATGAAGCTCTGAAACATATGAAAGATACTGACCCTCCAGAAACAGTACAAAGCTGGATTGAATATCTGAGTGGTGAAACATGGAATCCAATGAAACTGAAATACCAGTTAAAGAACGTACGCGAAAGATTGGCTAAAAATCTGGTTGAGAAAGGGGTTTTAACAACAGAAAAACAAAATTTTCTTTTATTTGACATGACGACACACCCTCTCACAGATAATGTCGTTAAGTGCCGTTTAGTTAAAAAGGTTCAAGAAGCAGCACTACGTCGTTCAATTACTGACGTAGCACATGCAGATAAAAGATCTTTAGCGTTATTGATGTTGGCACACTCAGCTGATGTGCTAGAGAATGCCTTCGCGCCCTTATCCGATGAAGACTACGAGTTGGCGACGCGGCGCGTGCGAGCCCTGCTTGATCTAGATTTCGAAGCGGAAGCCATGAGGCCCGATGCTTGTGAAATTATGTGGGCAGTGTTTGCGGCCTTCACTAAATAG

Protein

MNRTEGLVQRRNVIKESNTDGQKENHDNDDKKNDKNYDDGDSKETKLTLMEEVLLLGLKDKEGYTSFWNDCISSGLRGCILIELGLRGRLELERAGMRRKGLLSRKVIVKSDTLTGDVLLDEALKHMKDTDPPETVQSWIEYLSGETWNPMKLKYQLKNVRERLAKNLVEKGVLTTEKQNFLLFDMTTHPLTDNVVKCRLVKKVQEAALRRSITDVAHADKRSLALLMLAHSADVLENAFAPLSDEDYELATRRVRALLDLDFEAEAMRPDACEIMWAVFAAFTK

Description

Phosphatidylinositol-4-phosphate-binding protein that links Golgi membranes to the cytoskeleton and may participate in the tensile force required for vesicle budding from the Golgi (PubMed:19837035, PubMed:24786584). Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus (By similarity). May also bind to the coatomer to regulate Golgi membrane trafficking (PubMed:23720043, PubMed:24786584). May play a role in anterograde transport from the Golgi to the plasma membrane and regulate secretion (By similarity). Also involved in the control of the localization of Golgi enzymes through interaction with their cytoplasmic part (By similarity). Functions in cytokinesis by regulating contractile ring formation and vesicle trafficking during cleavage furrow ingression (PubMed:24786584). May also have a role in the intital steps of central spindle formation (PubMed:24786584). Can also bind phosphatidylinositol-3-phosphate and phosphatidylinositol-5-phosphate in vitro (PubMed:24786584).

Subunit

Homooligomer (By similarity). Interacts with botv, Ext2 and ttv (PubMed:23720043). Interacts with Vti1 (PubMed:23720043). Interacts with Vps35, Rab5, Chc, Rab11, zip, Pav and Sep1 (PubMed:24786584).

Similarity

Belongs to the GOLPH3/VPS74 family.

Keywords

Complete proteome   Cytoplasmic vesicle   Golgi apparatus   Lipid-binding   Membrane   Phosphoprotein   Protein transport   Reference proteome   Transport  

Feature

chain  Golgi phosphoprotein 3 homolog sauron

Uniprot

H9J1V3   A0A194PNJ3   A0A194QRJ5   A0A1E1WT39   A0A2A4JYZ0   A0A2H1WAF5   + More
A0A212ET87   S4PXT9   A0A1Y1MPI1   A0A1W4WZE5   D6W8D1   A0A067RGX0   A0A2P8ZHG8   A0A2J7Q7V0   N6UNE3   A0A023EML9   A0A087ZRX6   A0A232FI50   B4KFK8   A0A154PF86   A0A195CQK8   A0A034W9P0   W8CA44   A0A0L7QQ88   B0WPV9   T1PDC9   A0A1L8EE56   A0A2A3EPD2   A0A1Q3F7J0   E9ISK9   A0A151X3Z8   F4X402   A0A195E090   A0A195F326   A0A0K8UPV3   A0A182K379   A0A182PCG1   A0A2M4A878   A0A3B0JHI1   Q9VQ93   W5J1L2   A0A2M3ZFY3   A0A182F2A8   A0A0C9RMJ9   A0A0M4ES76   A0A182JI77   A0A182VB93   A0A182XGW4   A0A182KZ20   Q7PCS8   A0A182HRB3   A0A1W4UTK8   B3MJA4   A0A1I8PP59   A0A182NNX4   A0A084VCN2   B5DIC3   B4G952   B4LQM0   A0A182QXD6   A0A158NZZ3   B4MVV0   B3N9H7   B4NW70   A0A195BLJ6   A0A182W8T2   B4I2G7   B4Q804   B4JR05   A0A310SH65   E2BDG2   A0A0A1X2B8   A0A1L8E7N0   A0A182M8E1   A0A182RWS8   A0A182Y6C0   A0A0J7KZD1   A0A336JYK6   A0A026WNX3   E1ZVR1   A0A0L0CPH4   E0VAJ7   A0A1A9Y3T0   A0A1B0BV63   D3TQM9   A0A1A9UPW5   A0A1B0ABD4   A0A1A9WF10   Q17BE9   A0A0N7ZBS4   T1JEU6   A0A0K8TP42   A0A023F5H3   U5EYV9   A0A1J1IQU6   A0A069DR16   A0A0V0GDI9   A0A0A9ZC48   A0A0N7Z9K1  

Pubmed

19121390    26354079    22118469    23622113    28004739    18362917    + More
19820115    24845553    29403074    23537049    24945155    28648823    17994087    25348373    24495485    25315136    21282665    21719571    10731132    12537572    12537569    19837035    23720043    24786584    20920257    23761445    20966253    9087549    12364791    14747013    17210077    24438588    15632085    21347285    17550304    22936249    20798317    25830018    25244985    24508170    30249741    26108605    20566863    20353571    17510324    26369729    25474469    26334808    25401762    26823975    27129103   

EMBL

BABH01007944    KQ459597    KPI94887.1    KQ461181    KPJ07600.1    GDQN01001058    + More
JAT89996.1    NWSH01000406    PCG76630.1    ODYU01007289    SOQ49936.1    AGBW02012631    OWR44700.1    GAIX01004458    JAA88102.1    GEZM01025113    GEZM01025112    GEZM01025111    JAV87583.1    KQ971307    EFA10934.1    KK852474    KDR23086.1    PYGN01000057    PSN55948.1    NEVH01017002    PNF24664.1    APGK01024773    KB740562    KB632399    ENN80247.1    ERL94846.1    GAPW01003011    JAC10587.1    NNAY01000168    OXU30365.1    CH933807    EDW13123.1    KQ434879    KZC09968.1    KQ977394    KYN02991.1    GAKP01007528    JAC51424.1    GAMC01006101    JAC00455.1    KQ414799    KOC60656.1    DS232030    EDS32547.1    KA646792    AFP61421.1    GFDG01001828    JAV16971.1    KZ288200    PBC33577.1    GFDL01011538    JAV23507.1    GL765434    EFZ16317.1    KQ982557    KYQ55101.1    GL888624    EGI58794.1    KQ979955    KYN18560.1    KQ981856    KYN34582.1    GDHF01023939    GDHF01001931    JAI28375.1    JAI50383.1    GGFK01003619    MBW36940.1    OUUW01000004    SPP79752.1    AE014134    AY058532    ADMH02002168    ETN58087.1    GGFM01006681    MBW27432.1    GBYB01009568    GBYB01009569    GBYB01009570    JAG79335.1    JAG79336.1    JAG79337.1    CP012523    ALC40137.1    AAAB01007566    AAAB01008292    EAA03002.2    EAA03338.2    APCN01001664    CH902620    EDV31314.1    ATLV01010838    KE524620    KFB35726.1    CH379060    EDY70064.2    CH479180    EDW28882.1    CH940649    EDW64477.1    AXCN02001967    ADTU01005142    ADTU01005143    CH963857    EDW75820.1    CH954177    EDV57434.1    CM000157    EDW87350.1    KQ976440    KYM86560.1    CH480820    EDW53962.1    CM000361    CM002910    EDX03426.1    KMY87618.1    CH916372    EDV99335.1    KQ767007    OAD53529.1    GL447620    EFN86274.1    GBXI01008803    JAD05489.1    GFDG01004061    JAV14738.1    AXCM01014542    LBMM01001844    KMQ95658.1    UFQS01000030    UFQT01000030    SSW97826.1    SSX18212.1    KK107139    QOIP01000003    EZA57633.1    RLU24561.1    GL434618    EFN74728.1    JRES01000081    KNC34273.1    DS235006    EEB10403.1    JXJN01021148    EZ423731    ADD20007.1    CH477322    EAT43595.1    GDRN01079101    JAI62456.1    JH432130    GDAI01001489    JAI16114.1    GBBI01002303    JAC16409.1    GANO01001784    JAB58087.1    CVRI01000055    CRL01470.1    GBGD01002376    JAC86513.1    GECL01000663    JAP05461.1    GBHO01002138    GBRD01010458    GDHC01009191    JAG41466.1    JAG55366.1    JAQ09438.1    GDKW01000323    JAI56272.1   

Proteomes

UP000005204    UP000053268    UP000053240    UP000218220    UP000007151    UP000192223    + More
UP000007266    UP000027135    UP000245037    UP000235965    UP000019118    UP000030742    UP000005203    UP000215335    UP000009192    UP000076502    UP000078542    UP000053825    UP000002320    UP000095301    UP000242457    UP000075809    UP000007755    UP000078492    UP000078541    UP000075881    UP000075885    UP000268350    UP000000803    UP000000673    UP000069272    UP000092553    UP000075880    UP000075903    UP000076407    UP000075882    UP000007062    UP000075840    UP000192221    UP000007801    UP000095300    UP000075884    UP000030765    UP000001819    UP000008744    UP000008792    UP000075886    UP000005205    UP000007798    UP000008711    UP000002282    UP000078540    UP000075920    UP000001292    UP000000304    UP000001070    UP000008237    UP000075883    UP000075900    UP000076408    UP000036403    UP000053097    UP000279307    UP000000311    UP000037069    UP000009046    UP000092443    UP000092460    UP000078200    UP000092445    UP000091820    UP000008820    UP000183832   

PRIDE

H9J1V3    Q9VQ93   

Pfam

PF05719   GPP34

Interpro

IPR008628   GPP34-like        + More
IPR038261   GPP34-like_sf       

Gene 3D

1.10.3630.10    

ProteinModelPortal

H9J1V3   A0A194PNJ3   A0A194QRJ5   A0A1E1WT39   A0A2A4JYZ0   A0A2H1WAF5   + More
A0A212ET87   S4PXT9   A0A1Y1MPI1   A0A1W4WZE5   D6W8D1   A0A067RGX0   A0A2P8ZHG8   A0A2J7Q7V0   N6UNE3   A0A023EML9   A0A087ZRX6   A0A232FI50   B4KFK8   A0A154PF86   A0A195CQK8   A0A034W9P0   W8CA44   A0A0L7QQ88   B0WPV9   T1PDC9   A0A1L8EE56   A0A2A3EPD2   A0A1Q3F7J0   E9ISK9   A0A151X3Z8   F4X402   A0A195E090   A0A195F326   A0A0K8UPV3   A0A182K379   A0A182PCG1   A0A2M4A878   A0A3B0JHI1   Q9VQ93   W5J1L2   A0A2M3ZFY3   A0A182F2A8   A0A0C9RMJ9   A0A0M4ES76   A0A182JI77   A0A182VB93   A0A182XGW4   A0A182KZ20   Q7PCS8   A0A182HRB3   A0A1W4UTK8   B3MJA4   A0A1I8PP59   A0A182NNX4   A0A084VCN2   B5DIC3   B4G952   B4LQM0   A0A182QXD6   A0A158NZZ3   B4MVV0   B3N9H7   B4NW70   A0A195BLJ6   A0A182W8T2   B4I2G7   B4Q804   B4JR05   A0A310SH65   E2BDG2   A0A0A1X2B8   A0A1L8E7N0   A0A182M8E1   A0A182RWS8   A0A182Y6C0   A0A0J7KZD1   A0A336JYK6   A0A026WNX3   E1ZVR1   A0A0L0CPH4   E0VAJ7   A0A1A9Y3T0   A0A1B0BV63   D3TQM9   A0A1A9UPW5   A0A1B0ABD4   A0A1A9WF10   Q17BE9   A0A0N7ZBS4   T1JEU6   A0A0K8TP42   A0A023F5H3   U5EYV9   A0A1J1IQU6   A0A069DR16   A0A0V0GDI9   A0A0A9ZC48   A0A0N7Z9K1  

PDB

3KN1     E-value=9.17483e-77,     Score=728

KEGG

101743324    K15620 golgi phosphoprotein 3 | (RefSeq) Golgi phosphoprotein 3 homolog rotini

GO

GO:0070273   GO:0031985   GO:0005802   GO:0048194   GO:0006890   GO:0000139   GO:0005829   GO:0043001   GO:0007030   GO:0036089   GO:0010314   GO:0000281   GO:0007110   GO:0007112   GO:0000301   GO:0017137   GO:0007111   GO:0090307   GO:0032154   GO:0070300   GO:0032266   GO:0005794   GO:0000915   GO:0007053   GO:0031410   GO:0051225   GO:0015031   GO:0048193   GO:0008152   GO:0004190   GO:0006508   GO:0016021   GO:0004889   GO:0005216   GO:0045211   GO:0006281   GO:0048384  

PANTHER

PTHR12704  

Subcellular location

Golgi apparatus membrane   Phosphatidylinositol 4-phosphate-binding and oligomerization participate in the recruitment onto Golgi membranes (PubMed:23720043). In dividing cells associates with vesicles in polar regions of the cells during metaphase and anaphase, and localizes to the cleavage furrow during telophase (PubMed:24786584).   With evidence from 4 publications.
Cytoplasmic vesicle   Phosphatidylinositol 4-phosphate-binding and oligomerization participate in the recruitment onto Golgi membranes (PubMed:23720043). In dividing cells associates with vesicles in polar regions of the cells during metaphase and anaphase, and localizes to the cleavage furrow during telophase (PubMed:24786584).   With evidence from 4 publications.
Cleavage furrow   Phosphatidylinositol 4-phosphate-binding and oligomerization participate in the recruitment onto Golgi membranes (PubMed:23720043). In dividing cells associates with vesicles in polar regions of the cells during metaphase and anaphase, and localizes to the cleavage furrow during telophase (PubMed:24786584).   With evidence from 4 publications.

Length:

285

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00682999999999999

Exp number, first 60 AAs:

0

Total prob of N-in:

0.08789

outside

1  -  285

 

 

Pi

284.461107

Theta

211.090551

Tajima's D

1.104304

CLR

0.003667

CSRT

0.686865656717164

Interpretation

Uncertain