Gene

KWMTBOMO02726  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA003725

Annotation

PREDICTED:_glycylpeptide_N-tetradecanoyltransferase_2_[Amyelois_transitella]

Location

Bomo_Chr5(-):9635756-9637330      View in EpiBrowser

Full name

Glycylpeptide N-tetradecanoyltransferase      

Location in the cell

Cytoplasmic   Reliability : 3.078

CDS

ATGGAAGAAACGAAAACGGGCGTATCTTGTGATTTTAGTAAAGAAAACGATGAGAAACCTCAGAAAAAGAAAAATAAAAACAAGAAAAAACGTGGTGGAGACGGAGATCATGGTATATCTACGGCAAATGAGAGTTCGTCATCAATGCCAGATCCAACTGAAGGTCATCAAAACATTTCATTAAAAGACTTAAAAATGGCAATGGAGGTACTAAATTTACAGCAAAAGCCTGCAAAAACTACAGAGGAGGCATTGCATAAAGCATACCAATTCTGGTCAACCCAACCGGTGCCAAAAATGGATGAAAAAATTATTGCCAACGAGCCTATAGAACTACCAAAATCACCGGAAGAAATAAGGGCAGAACCCTATACTTTACCTGACGGATTCCAATGGGATACTTTGAATTTGAACGAACCTTTAGTATTGAAAGAACTGTACACTTTACTTAATGAAAATTATGTGGAAGATGATGATTGTATGTTTCGTTTTGATTACCAAACTGATTTTTTGAAATGGGCTCTACAACCACCTGGTTGGAAAATGGAATGGCATTGTGGTGTTCGTGTGGTGAAATCTGGACGGCTTGTTGGTTTCATTTCAGCAACTCCTGCTGATTTAAGAATATATAACCATGTTCAAACTGTTGTTGAAATAAATTTTCTTTGTGTGCACAAAAAATTGCGTTCTAAGCGAGTAGCTCCTGTCTTAATAAGGGAAATAACAAGAAGAGTTAACTTAACTGGTATATTCCAGGGTGTGTATACAGCTGGAATTGTGTTGCCTAAGCCTATTGCCACATGTCGCTATTGGCATAGGTCTCTTAATCCAAAGAAATTAATTGACATAAAATTCAGTCATTTGTCACGTAATATGACAATGCAAAGAACGCTTAAACTCTTTAAGTTACCAGACATGCCAAAAACACCAGGTTTCCGCAAAATGGAGATTCAAGACTGTGAAGCAGTAGTAAAATTACTCAATGATTACTTAAAAAAATTTGATTTGGCACCTATATTTTCTGATGAAGATTTTAAACATTGGTTTACACCACAAGTGGGAATAATTGATAGTTTTGTTGTGGAAGGTCCTAATTCTACAATAACTGATTTCGTCAGTTATTATACATTGCCTTCAACTGTTGTTTACCATCCAGTGCACAAAACACTAAAAGCAGCTTATTCATTCTATAATGTGTCAACCAAGACACCTTGGGTGGATTTGATGCTGGATGCATTAATAACAGCAAAAAATTCAGGATTTGATGTGTTTAATGCACTAGATTTGATGGATAACAAAGAATTTCTTGAACCTCTGAAATTTGGGATTGGTGATGGAAATTTGCAATATTATTTGTATAATTGGAGATGTCCTAGTATGGCCCCGAATAAAATTGGTCTGGTACTTCAATAA

Protein

MEETKTGVSCDFSKENDEKPQKKKNKNKKKRGGDGDHGISTANESSSSMPDPTEGHQNISLKDLKMAMEVLNLQQKPAKTTEEALHKAYQFWSTQPVPKMDEKIIANEPIELPKSPEEIRAEPYTLPDGFQWDTLNLNEPLVLKELYTLLNENYVEDDDCMFRFDYQTDFLKWALQPPGWKMEWHCGVRVVKSGRLVGFISATPADLRIYNHVQTVVEINFLCVHKKLRSKRVAPVLIREITRRVNLTGIFQGVYTAGIVLPKPIATCRYWHRSLNPKKLIDIKFSHLSRNMTMQRTLKLFKLPDMPKTPGFRKMEIQDCEAVVKLLNDYLKKFDLAPIFSDEDFKHWFTPQVGIIDSFVVEGPNSTITDFVSYYTLPSTVVYHPVHKTLKAAYSFYNVSTKTPWVDLMLDALITAKNSGFDVFNALDLMDNKEFLEPLKFGIGDGNLQYYLYNWRCPSMAPNKIGLVLQ

Description

Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.

Catalytic Activity

N-terminal glycyl-[protein] + tetradecanoyl-CoA = CoA + H(+) + N-tetradecanoylglycyl-[protein]

Similarity

Belongs to the NMT family.

Uniprot

H9J2I8   A0A2H1WVX7   A0A2W1B971   A0A1E1W6D7   A0A2A4JN47   A0A194PPD7   + More
A0A194RFY9   A0A0L7KPX0   A0A212FJ00   S4NK99   A0A1Y1N3L6   A0A1W4WFE4   A0A1B6DI98   A0A2J7QUZ0   A0A0C9QK64   A0A067QR46   A0A0T6BBQ2   E9IQ13   A0A151I280   A0A151J669   F4WSI5   A0A158NRE0   A0A0A9X9A8   A0A224XPY2   A0A0V0G975   A0A151X618   A0A026X086   A0A195EXL0   S6D9I6   A0A069DU61   A0A154P1P5   A0A1B6M6A3   E2ADC0   K7INE9   A0JCZ1   E2C0S6   A0A0L7RCQ8   B7S8A8   A0A0M9AB74   A0A088AMF3   V5G9K7   T1HP74   A0A2A3EHH8   A0A0A9XA49   D2A651   U5EYD7   U4UGU2   U4U9S9   A0A182HGS8   A0A084VAJ6   Q7PY97   A0A182X2Q9   A0A182KMB6   A0A2H8TF45   A0A182JPZ5   A0A182QCW1   A0A182P9S8   A0A182JGT2   A0A182XV91   A0A2S2QCQ3   U5EP13   A0A182F6U9   A0A2M4ADW8   A0A182VA87   A0A182M789   A0A2M4BIG1   A0A182VRI7   A0A2M4ACJ1   A0A2M4BIG0   A0A2M4BJ70   A0A182RNZ5   W5JKM4   A0A182UJK6   A0A182NFK0   A0A1E1XGS0   A0A023FMG3   A0A131XG87   A0A2M3ZGY0   L7LXT0   A0A224YQS2   A0A131Z756   J9JVX2   B0XIR1   T1E203   A0A2M3Z7U4   A0A1Q3F6P2   N6T6Q1   Q17B42   A0A0P6ATE7   A0A0P4ZE44   A0A182H5P0   A0A0P5DMZ0   A0A0P5UAJ8   A0A0N8CL07   A0A0N7ZSE4   A0A0N7ZNT8   A0A0P6JA25   A0A0P5CD89   A0A0N7ZPP4   A0A0P4ZMQ1  

EC Number

2.3.1.97

Pubmed

19121390    28756777    26354079    26227816    22118469    23622113    + More
28004739    24845553    21282665    21719571    21347285    25401762    26823975    24508170    30249741    23938757    26334808    20798317    20075255    18362917    19820115    23537049    24438588    12364791    14747013    17210077    20966253    25244985    20920257    23761445    28503490    28049606    25576852    28797301    26830274    24330624    17510324    26483478   

EMBL

BABH01008004    ODYU01011465    SOQ57210.1    KZ150495    PZC70674.1    GDQN01008502    + More
JAT82552.1    NWSH01000990    PCG73206.1    KQ459597    KPI94843.1    KQ460207    KPJ16728.1    JTDY01007562    KOB65111.1    AGBW02008321    OWR53700.1    GAIX01013389    JAA79171.1    GEZM01013523    JAV92511.1    GEDC01011943    JAS25355.1    NEVH01010480    PNF32398.1    GBYB01000997    GBYB01000998    JAG70764.1    JAG70765.1    KK853123    KDR11094.1    LJIG01002182    KRT84758.1    GL764659    EFZ17329.1    KQ976549    KYM80904.1    KQ979928    KYN18602.1    GL888322    EGI62850.1    ADTU01023942    GBHO01027391    GBHO01027388    GBRD01013269    GDHC01000425    JAG16213.1    JAG16216.1    JAG52557.1    JAQ18204.1    GFTR01006355    JAW10071.1    GECL01001663    JAP04461.1    KQ982494    KYQ55740.1    KK107054    QOIP01000004    EZA61503.1    RLU24128.1    KQ981923    KYN32963.1    HF586472    CCQ71106.1    GBGD01001429    JAC87460.1    KQ434796    KZC05777.1    GEBQ01008539    JAT31438.1    GL438749    EFN68536.1    AC191960    ABK57056.1    GL451846    EFN78470.1    KQ414615    KOC68536.1    EF710644    ACE75132.1    KQ435711    KOX79589.1    GALX01001641    JAB66825.1    ACPB03012986    KZ288248    PBC31158.1    GBHO01027941    GBHO01027392    GBRD01013271    JAG15663.1    JAG16212.1    JAG52555.1    KQ971346    EFA05466.1    GANO01000362    JAB59509.1    KB632191    ERL89816.1    ERL89817.1    APCN01005945    ATLV01004127    KE524190    KFB34990.1    AAAB01008987    EAA01164.5    GFXV01000896    MBW12701.1    AXCN02000208    GGMS01006304    MBY75507.1    GANO01000361    JAB59510.1    GGFK01005663    MBW38984.1    AXCM01002852    GGFJ01003698    MBW52839.1    GGFK01005121    MBW38442.1    GGFJ01003699    MBW52840.1    GGFJ01003697    MBW52838.1    ADMH02001255    ETN63435.1    GFAC01000701    JAT98487.1    GBBK01002442    JAC22040.1    GEFH01002067    JAP66514.1    GGFM01007018    MBW27769.1    GACK01008632    JAA56402.1    GFPF01008119    MAA19265.1    GEDV01002291    JAP86266.1    ABLF02023070    DS233355    EDS29583.1    GALA01001189    JAA93663.1    GGFM01003824    MBW24575.1    GFDL01011897    JAV23148.1    APGK01050185    APGK01050186    KB741167    ENN73373.1    CH477326    EAT43469.1    GDIP01024709    JAM79006.1    GDIP01227232    GDIP01135157    LRGB01001151    JAI96169.1    KZS13435.1    JXUM01112158    KQ565567    KXJ70872.1    GDIP01154093    JAJ69309.1    GDIP01119452    JAL84262.1    GDIP01121391    JAL82323.1    GDIP01217185    JAJ06217.1    GDIP01227233    JAI96168.1    GDIQ01010513    JAN84224.1    GDIP01188229    JAJ35173.1    GDIP01224785    JAI98616.1    GDIP01214779    JAJ08623.1   

Proteomes

UP000005204    UP000218220    UP000053268    UP000053240    UP000037510    UP000007151    + More
UP000192223    UP000235965    UP000027135    UP000078540    UP000078492    UP000007755    UP000005205    UP000075809    UP000053097    UP000279307    UP000078541    UP000076502    UP000000311    UP000002358    UP000008237    UP000053825    UP000053105    UP000005203    UP000015103    UP000242457    UP000007266    UP000030742    UP000075840    UP000030765    UP000007062    UP000076407    UP000075882    UP000075881    UP000075886    UP000075885    UP000075880    UP000076408    UP000069272    UP000075903    UP000075883    UP000075920    UP000075900    UP000000673    UP000075902    UP000075884    UP000007819    UP000002320    UP000019118    UP000008820    UP000076858    UP000069940    UP000249989   

PRIDE

H9J2I8    L7LXT0   

Pfam

PF01233   NMT        + More
PF02799   NMT_C
PF16207   RAWUL
PF00071   Ras
PF08920   SF3b1

Interpro

IPR016181   Acyl_CoA_acyltransferase        + More
IPR022678   MyristoylCoA_TrFase_CS       
IPR022676   MyristoylCoA_TrFase_N       
IPR022677   MyristoylCoA_TrFase_C       
IPR000903   MyristoylCoA_TrFase       
IPR027417   P-loop_NTPase       
IPR017907   Znf_RING_CS       
IPR034085   TOG       
IPR038737   SF3b_su1-like       
IPR011989   ARM-like       
IPR015016   SF3b_su1       
IPR001841   Znf_RING       
IPR001806   Small_GTPase       
IPR032443   RAWUL       
IPR005225   Small_GTP-bd_dom       
IPR016024   ARM-type_fold       
IPR013083   Znf_RING/FYVE/PHD       

SUPFAM

SSF55729   SSF55729        + More
SSF48371   SSF48371       
SSF52540   SSF52540       

Gene 3D

1.25.10.10     3.30.40.10    

ProteinModelPortal

H9J2I8   A0A2H1WVX7   A0A2W1B971   A0A1E1W6D7   A0A2A4JN47   A0A194PPD7   + More
A0A194RFY9   A0A0L7KPX0   A0A212FJ00   S4NK99   A0A1Y1N3L6   A0A1W4WFE4   A0A1B6DI98   A0A2J7QUZ0   A0A0C9QK64   A0A067QR46   A0A0T6BBQ2   E9IQ13   A0A151I280   A0A151J669   F4WSI5   A0A158NRE0   A0A0A9X9A8   A0A224XPY2   A0A0V0G975   A0A151X618   A0A026X086   A0A195EXL0   S6D9I6   A0A069DU61   A0A154P1P5   A0A1B6M6A3   E2ADC0   K7INE9   A0JCZ1   E2C0S6   A0A0L7RCQ8   B7S8A8   A0A0M9AB74   A0A088AMF3   V5G9K7   T1HP74   A0A2A3EHH8   A0A0A9XA49   D2A651   U5EYD7   U4UGU2   U4U9S9   A0A182HGS8   A0A084VAJ6   Q7PY97   A0A182X2Q9   A0A182KMB6   A0A2H8TF45   A0A182JPZ5   A0A182QCW1   A0A182P9S8   A0A182JGT2   A0A182XV91   A0A2S2QCQ3   U5EP13   A0A182F6U9   A0A2M4ADW8   A0A182VA87   A0A182M789   A0A2M4BIG1   A0A182VRI7   A0A2M4ACJ1   A0A2M4BIG0   A0A2M4BJ70   A0A182RNZ5   W5JKM4   A0A182UJK6   A0A182NFK0   A0A1E1XGS0   A0A023FMG3   A0A131XG87   A0A2M3ZGY0   L7LXT0   A0A224YQS2   A0A131Z756   J9JVX2   B0XIR1   T1E203   A0A2M3Z7U4   A0A1Q3F6P2   N6T6Q1   Q17B42   A0A0P6ATE7   A0A0P4ZE44   A0A182H5P0   A0A0P5DMZ0   A0A0P5UAJ8   A0A0N8CL07   A0A0N7ZSE4   A0A0N7ZNT8   A0A0P6JA25   A0A0P5CD89   A0A0N7ZPP4   A0A0P4ZMQ1  

PDB

1RXT     E-value=3.79993e-168,     Score=1519

KEGG

101735807    K00671 glycylpeptide N-tetradecanoyltransferase [EC:2.3.1.97] | (RefSeq) glycylpeptide N-tetradecano

GO

GO:0006499   GO:0004379   GO:0018008   GO:0005737   GO:0003924   GO:0005525   GO:0000245   GO:0003729   GO:0005739   GO:0003676   GO:0006412   GO:0004823   GO:0006429   GO:0006631   GO:0006635   GO:0006281   GO:0048384  

PANTHER

PTHR11377   PTHR12097  

Length:

470

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.10551

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00952

outside

1  -  470

 

 

Pi

242.783172

Theta

219.178584

Tajima's D

0.339107

CLR

0.157768

CSRT

0.468976551172441

Interpretation

Uncertain