Gene

KWMTBOMO02715

Pre Gene Modal

BGIBMGA003465

Annotation

PREDICTED:_negative_elongation_factor_D_[Amyelois_transitella]

Location

Bomo_Chr5(+):9527111-9546559      View in EpiBrowser

Full name

Negative elongation factor D      

Location in the cell

Cytoplasmic   Reliability : 2.437

CDS

ATGCCTAGTCAGTATGAGGAAGAACGTGTATGGGATGGTCAGAATCATAATAATCAATATGAAGAAGAAGGAAATGAAGATGTTATTGAGAACCCTGAAGAGGTATTAAATGAATGTCTGGAAAAATTTAAAACTCCAGACTACATTATGGAACCTGGTATTTTTGGTCAGCTTAAAAGATACTTCCAAGCTGGTGGAAATCCAGAGCAAGTTATTGAACAACTGTCAATGAATTACAATGCTGTAGCTCAGATGGCCAACTTATTAGCTGAATGGCTTATCCTTGGAGGAGTTAAAGTTAGTGAAGTCCAAGCTATGGTTGAAAATCATTTAAAAGACATGATTCTAAAAACATTTGATCCCAAAAAAGCTGATACAATATTCACTGAAGAGGGAGAGACACCAGCTTGGCTTACTGAGATGATTGAACATCCTACTTGGAGATCTTTAATTTACAGACTAGCCGAAGAATATCCAGATTGTCTAATGTTAAATTTTACTATAAAGTTAATTTCTGATGCAGGTTTTCAAGGTGAGATAACAAGCATATCAACAGCTGCACAACAAATCGAAGTATTCTCCAGAGTACTCAAATCAGCTATTGTGGGTTTCCTTCAAAGTTCAGATGATTGGCAAAACAGTGTTAATGAATGTGCTAAAATGGTTTGTCATGGCGCGCACACATACGTTTACAGTCAAGTTATTGTTCACATTCTCTCACAAGAGCCAAGAGGTGGCGCTATTATGAAGAGGTTGAGCCAGGAAATAACTCGTTGTGCTCAACAAGGTGGCCACGATGTGACCCCAATAACACTGGCCTTGACCTCTGGTGAGAGTTGGCGCAACGCTCGGACGGCACTTGCAGCCATGCTATCGAGGGGCGCCCTCAATCCGGCTGATATCTCGGTGTTGTTCCGCGCTTACACGCAACCAGACTCGCCACCGGTTCATTTACTTAGGATACCACAGTTTTTGGAACTACTCGTTGATTCATTGTTCAAATTGGGAAGCAAACTGAATCCGGAACACAAATCCAAATATATGTATCTTTTGGCATACGCTGCTAGCGTTTGCGAAAGTCCGAGTCCCGGTAAACCTGTTAAAGACGAACTAAAGGCCACTGTGCAAGCTATTGAAAAAGTACATGCCGTGTGCAGCAGCTCTGCTAGCTCCAGCGAACTCATCGCCGAATTACCTACTCTATACCATTGTATAAGATTCCCCGTAGTCGGTATGGGAGTTTTAGTTTGGGTGGAGTGTGTTGTGACCGAACCTTCGTATTTCAAACTCTGTACAGAACATTGTCCTTTGCACCTGGCGCTATTAGACGAGGTCGCGTCTTGTCATCCACTGTTGCATCACAGGCTCTTGAGATTATTAGTGAAACTCTTTGAATCGCCACAAGACGAACTAGAGATATTAGTCCAGCTTGAATTGAAAAAGATGCTTTTGGATCGAATGGTGAATTTATTAAGTCGCGGTTGTGTTGTCCCCGTTCTTAGATACATTAAACAGTGCTGGCAGCGCGGAGATACAGATATTTCGTTGATTAGATACTTCATAACTGAGGTTTTGGACGCAATAGCACCGCCGTACACGCCCGAGTTCGTACAACTTGTCCTACCCATGGTAGAGAATGAAGAAATAACCGGAACGATGAGAGCAGAAGGTGAAAACGATCCAGTTTCTGAATTTATAGTTCATTGCAAGGCACATTTCGTCGTTGTTTGA

Protein

MPSQYEEERVWDGQNHNNQYEEEGNEDVIENPEEVLNECLEKFKTPDYIMEPGIFGQLKRYFQAGGNPEQVIEQLSMNYNAVAQMANLLAEWLILGGVKVSEVQAMVENHLKDMILKTFDPKKADTIFTEEGETPAWLTEMIEHPTWRSLIYRLAEEYPDCLMLNFTIKLISDAGFQGEITSISTAAQQIEVFSRVLKSAIVGFLQSSDDWQNSVNECAKMVCHGAHTYVYSQVIVHILSQEPRGGAIMKRLSQEITRCAQQGGHDVTPITLALTSGESWRNARTALAAMLSRGALNPADISVLFRAYTQPDSPPVHLLRIPQFLELLVDSLFKLGSKLNPEHKSKYMYLLAYAASVCESPSPGKPVKDELKATVQAIEKVHAVCSSSASSSELIAELPTLYHCIRFPVVGMGVLVWVECVVTEPSYFKLCTEHCPLHLALLDEVASCHPLLHHRLLRLLVKLFESPQDELEILVQLELKKMLLDRMVNLLSRGCVVPVLRYIKQCWQRGDTDISLIRYFITEVLDAIAPPYTPEFVQLVLPMVENEEITGTMRAEGENDPVSEFIVHCKAHFVVV

Description

Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex, causes transcriptional pausing.

Subunit

Component of the NELF complex, which is at least composed of TH1/NELF-D and NELF-E.

Similarity

Belongs to the NELF-D family.

Keywords

Chromosome   Complete proteome   Nucleus   Reference proteome   Repressor   Transcription   Transcription regulation  

Feature

chain  Negative elongation factor D

Uniprot

A0A194PN29   A0A212FIY2   A0A2A4JJ27   S4PDX1   E2A694   A0A154P4E0   + More
A0A151XFX5   A0A195BJH6   A0A158NFD6   F4WUI5   A0A151IAM7   E2BF17   A0A1B6LG52   A0A0M9A0M3   K7IVZ7   A0A2A3EMV0   A0A2J7PEV3   A0A0P4VZT2   A0A023F4C1   A0A224XH36   A0A1B6FST0   A0A069DVT7   A0A1S4ENA4   A0A3L8DF74   A0A0V0G597   E0VZW3   A0A182G697   Q17I80   A0A1W4XFD7   A0A182QE03   W8BTF3   A0A182N8H0   B0WYR4   A0A0K8VFP8   D6WGW8   A0A182W5N4   A0A034VZK1   A0A1I8MVZ1   A0A182J212   A0A084VVI0   A0A1Y1L0M6   A0A0A1WHC8   A0A0A9X0I5   A0A1Y1L0N8   A0A1A9VRF2   A0A1Q3F1X1   A0A034W332   A0A1I8PKM4   A0A182MUZ5   U5EW57   A0A0L0C5B6   A0A182PSW0   A0A182TKE2   A0A182XJY1   N6UGB4   Q7QFB3   B4L8R7   A0A1B0FBJ4   A0A1A9XDX4   A0A1B0B8I5   A0A182KDT7   A0A1A9ZLV3   B4NEV2   A0A1B0CLI2   A0A3B0K3F2   Q29GI5   B3N0R9   A0A1A9WFD1   A0A0M4F8B7   B4M1S3   A0A1W4VVQ9   B4R5T7   X2JE29   B4JVP8   Q24134   B4PXS8   B4IF72   A0A182YCW6   B3NX44   A0A336LKN1   A0A1W4VHL6   A0A1L8DS37   A0A194RFX7   A0A182VKE6   A0A1Q3F241   E9G5E8   A0A2H8TMZ0   J9JYS3   A0A0P5IWM5   A0A0P6BXT3   A0A232FMB7   A0A182SYJ6   A0A2H1VS99   A0A0P5NCB7   A0A3B0KXH1   A0A0P5SN33   A0A2S2QL12   T1J261   A0A087V0R6   A0A0N7ZD63  

Pubmed

26354079    22118469    23622113    20798317    21347285    21719571    + More
20075255    27129103    25474469    26334808    30249741    20566863    26483478    17510324    24495485    18362917    19820115    25348373    25315136    24438588    28004739    25830018    25401762    26823975    26108605    23537049    12364791    14747013    17210077    17994087    15632085    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    11030415    12537569    7671309    12782658    15741180    17550304    25244985    21292972    28648823   

EMBL

KQ459597    KPI94836.1    AGBW02008321    OWR53707.1    NWSH01001393    PCG71402.1    + More
GAIX01003461    JAA89099.1    GL437123    EFN70979.1    KQ434813    KZC06786.1    KQ982182    KYQ59180.1    KQ976464    KYM84552.1    ADTU01014283    GL888365    EGI62150.1    KQ978186    KYM96552.1    GL447910    EFN85695.1    GEBQ01017368    JAT22609.1    KQ435775    KOX74945.1    KZ288206    PBC33058.1    NEVH01026087    PNF14869.1    GDKW01000498    JAI56097.1    GBBI01002356    JAC16356.1    GFTR01007298    JAW09128.1    GECZ01016483    JAS53286.1    GBGD01000958    JAC87931.1    QOIP01000009    RLU19034.1    GECL01003268    JAP02856.1    DS235854    EEB18919.1    JXUM01044520    KQ561404    KXJ78690.1    CH477242    EAT46347.1    AXCN02002232    GAMC01004098    JAC02458.1    DS232196    EDS37174.1    GDHF01014631    JAI37683.1    KQ971321    EFA00603.1    GAKP01010256    JAC48696.1    ATLV01017185    KE525157    KFB41974.1    GEZM01068080    JAV67222.1    GBXI01016387    JAC97904.1    GBHO01030100    GBRD01004466    GDHC01011868    JAG13504.1    JAG61355.1    JAQ06761.1    GEZM01068079    JAV67223.1    GFDL01013490    JAV21555.1    GAKP01010255    JAC48697.1    AXCM01004821    GANO01000708    JAB59163.1    JRES01000902    KNC27432.1    APGK01021773    APGK01021774    APGK01021775    KB740363    KB631964    ENN80800.1    ERL87502.1    AAAB01008846    EAA06287.4    CH933815    EDW08042.1    CCAG010006490    JXJN01009947    CH964239    EDW82271.1    AJWK01017305    AJWK01017306    AJWK01017307    OUUW01000015    SPP88767.1    CH379064    EAL32124.1    CH902644    EDV34798.1    CP012528    ALC48587.1    CH940651    EDW65627.1    CM000366    EDX18087.1    AE014298    AHN59796.1    CH916375    EDV98516.1    AJ238377    AJ238378    L01790    AY051957    U34925    CM000162    EDX01914.1    CH480832    EDW46126.1    CH954180    EDV46873.1    UFQT01000005    SSX17301.1    GFDF01004798    JAV09286.1    KQ460207    KPJ16718.1    GFDL01013433    JAV21612.1    GL732532    EFX85644.1    GFXV01003207    MBW15012.1    ABLF02036108    GDIQ01209548    LRGB01000568    JAK42177.1    KZS18019.1    GDIP01012813    JAM90902.1    NNAY01000040    OXU31649.1    ODYU01004151    SOQ43715.1    GDIQ01166809    JAK84916.1    SPP88768.1    GDIP01141142    JAL62572.1    GGMS01008669    MBY77872.1    JH431796    KL814470    KFM83205.1    GDRN01051780    JAI66368.1   

Proteomes

UP000053268    UP000007151    UP000218220    UP000000311    UP000076502    UP000075809    + More
UP000078540    UP000005205    UP000007755    UP000078542    UP000008237    UP000053105    UP000002358    UP000242457    UP000235965    UP000079169    UP000279307    UP000009046    UP000069940    UP000249989    UP000008820    UP000192223    UP000075886    UP000075884    UP000002320    UP000007266    UP000075920    UP000095301    UP000075880    UP000030765    UP000078200    UP000095300    UP000075883    UP000037069    UP000075885    UP000075902    UP000076407    UP000019118    UP000030742    UP000007062    UP000009192    UP000092444    UP000092443    UP000092460    UP000075881    UP000092445    UP000007798    UP000092461    UP000268350    UP000001819    UP000007801    UP000091820    UP000092553    UP000008792    UP000192221    UP000000304    UP000000803    UP000001070    UP000002282    UP000001292    UP000076408    UP000008711    UP000053240    UP000075903    UP000000305    UP000007819    UP000076858    UP000215335    UP000075901    UP000054359   

PRIDE

Q24134   

Pfam

PF04858   TH1

Interpro

IPR006942   TH1        + More
IPR016024   ARM-type_fold       

SUPFAM

SSF48371   SSF48371       

ProteinModelPortal

A0A194PN29   A0A212FIY2   A0A2A4JJ27   S4PDX1   E2A694   A0A154P4E0   + More
A0A151XFX5   A0A195BJH6   A0A158NFD6   F4WUI5   A0A151IAM7   E2BF17   A0A1B6LG52   A0A0M9A0M3   K7IVZ7   A0A2A3EMV0   A0A2J7PEV3   A0A0P4VZT2   A0A023F4C1   A0A224XH36   A0A1B6FST0   A0A069DVT7   A0A1S4ENA4   A0A3L8DF74   A0A0V0G597   E0VZW3   A0A182G697   Q17I80   A0A1W4XFD7   A0A182QE03   W8BTF3   A0A182N8H0   B0WYR4   A0A0K8VFP8   D6WGW8   A0A182W5N4   A0A034VZK1   A0A1I8MVZ1   A0A182J212   A0A084VVI0   A0A1Y1L0M6   A0A0A1WHC8   A0A0A9X0I5   A0A1Y1L0N8   A0A1A9VRF2   A0A1Q3F1X1   A0A034W332   A0A1I8PKM4   A0A182MUZ5   U5EW57   A0A0L0C5B6   A0A182PSW0   A0A182TKE2   A0A182XJY1   N6UGB4   Q7QFB3   B4L8R7   A0A1B0FBJ4   A0A1A9XDX4   A0A1B0B8I5   A0A182KDT7   A0A1A9ZLV3   B4NEV2   A0A1B0CLI2   A0A3B0K3F2   Q29GI5   B3N0R9   A0A1A9WFD1   A0A0M4F8B7   B4M1S3   A0A1W4VVQ9   B4R5T7   X2JE29   B4JVP8   Q24134   B4PXS8   B4IF72   A0A182YCW6   B3NX44   A0A336LKN1   A0A1W4VHL6   A0A1L8DS37   A0A194RFX7   A0A182VKE6   A0A1Q3F241   E9G5E8   A0A2H8TMZ0   J9JYS3   A0A0P5IWM5   A0A0P6BXT3   A0A232FMB7   A0A182SYJ6   A0A2H1VS99   A0A0P5NCB7   A0A3B0KXH1   A0A0P5SN33   A0A2S2QL12   T1J261   A0A087V0R6   A0A0N7ZD63  

PDB

6GML     E-value=6.2009e-172,     Score=1552

KEGG

101737028    K15181 negative elongation factor C/D | (RefSeq) negative elongation factor D

GO

GO:0045892   GO:0005634   GO:0003746   GO:0003723   GO:0032021   GO:0034244   GO:0016021   GO:0005705   GO:0005703   GO:0017053   GO:0008023   GO:0000122   GO:0005737   GO:0006397   GO:0006813   GO:0008076   GO:0006631   GO:0006635   GO:0006281   GO:0048384  

PANTHER

PTHR12144  

Subcellular location

Nucleus  
Chromosome  

Length:

576

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0651100000000002

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00282

outside

1  -  576

 

 

Pi

3.450033

Theta

191.001285

Tajima's D

2.340824

CLR

0.226775

CSRT

0.926103694815259

Interpretation

Uncertain