SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO02658
Annotation
PREDICTED:_snurportin-1_[Amyelois_transitella]
Full name
Snurportin-1      
Alternative Name
RNA U transporter 1
Location in the cell
Cytoplasmic   Reliability : 1.487 Nuclear   Reliability : 1.613
 

Sequence

CDS
ATGGATGATATTATACAAAAAATAGCTTCTACTGCAATCCATTTCGAGGATAAGGATGCCAGTAAAACCATGTTTAAAGACCTTTACAAAAATAGAGAAAAGAGTAATAACCAAGAAGAGAGACGAAAAAAAATGCTGGAAGTTCAAAAGTGTAACCGCAATGCTACCACAGACACATTTAGGGGCATATTAGACATTGTAAATAGTGTCGACACAACAGAAGATTATTTTGGTTCTACAACACAGACTTACTATAGACCGAATATATATGTTGCAGGCTTTGTTAAAGCCCCATCATCATACTATAATGTATTGATGATTTCTGAATGGATGGTAGAAAAACCCTCTGATTTTGCTCAGAATTGGTATGTTGTACCATGTCCAAAAGGTAGTAGAGTGTTGATTGTTGCTAATAATGGTAGAACCAAATTATATAATAAGTATGGAAGATTTAGATTAGATACTAAAACTCTGCTGCCGGGTGGCCATCCTAATAAAGGATATCAGAAAACTGATTGCTGTGTTCTAGATGGTTTTTATGATTCTCTATCGAATAGTGTTTACATTCTTGATTTACTGGCATGGAATAATCAGGCCATGACTGATGGAGAGACTGATTTTCGACATTTTTGGCTACAAACTCAAGTTTTTATAATACAGGGACTGAACGTACTTAGCAAGGTCAATAAGTTAAAATTTTTTTTACTACCCAAGGTACCTTGTTCCCGTGAAGAATTAAACCAGTTCATGATGACATATCCAGCATTTGAAAATTACATACCAGCACTAGATGGTCTATTATTCTATCACAAAAAGACCCATTACATCTCAGGACAGACTCCACTGGTTGGATGGCTGTATCCATTCATGGTAAAAGAAGTACTTGGATATGACATAACCGTTCACGAGTCGTATAATTTAGAGCGACCCGAAGATTATACAAATCAAGCAGATTACATCGTTCGGTTCGAAGAGAGAAAGACGAGGACCAAACAAAGTAAACTAGATAGACTGAGGATCACTCAAATGCAGATTGGTGACTACGAATCGGGCGAAACATATTATTCCAGACTGTACAACATGGACGTCGGCGACTGTAATAACGAGGTACAACACCAAACCATACTTAAAGACAGATTTGGCCTCGTGGTTATGAGTTAG
Protein
MDDIIQKIASTAIHFEDKDASKTMFKDLYKNREKSNNQEERRKKMLEVQKCNRNATTDTFRGILDIVNSVDTTEDYFGSTTQTYYRPNIYVAGFVKAPSSYYNVLMISEWMVEKPSDFAQNWYVVPCPKGSRVLIVANNGRTKLYNKYGRFRLDTKTLLPGGHPNKGYQKTDCCVLDGFYDSLSNSVYILDLLAWNNQAMTDGETDFRHFWLQTQVFIIQGLNVLSKVNKLKFFLLPKVPCSREELNQFMMTYPAFENYIPALDGLLFYHKKTHYISGQTPLVGWLYPFMVKEVLGYDITVHESYNLERPEDYTNQADYIVRFEERKTRTKQSKLDRLRITQMQIGDYESGETYYSRLYNMDVGDCNNEVQHQTILKDRFGLVVMS

Summary

Description
Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs.
Subunit
Component of an import snRNP complex composed of KPNB1, SNUPN, SMN1 and ZNF259. Component of a nuclear export receptor complex composed of KPNB1, Ran, SNUPN and XPO1. Found in a trimeric export complex with SNUPN, Ran and XPO1. Interacts (via IBB domain) with KPNB1; the interaction is direct. Interacts with DDX20, IPO7, SMN1, SNRPB and XPO1. Interacts directly with XPO1. Its interaction with XPO1 and binding to m3G-cap U snRNPs appears to be mutually exclusive.
Similarity
Belongs to the snurportin family.
Keywords
Acetylation   Complete proteome   Cytoplasm   Nucleus   Phosphoprotein   Reference proteome   RNA-binding   Transport   3D-structure   Direct protein sequencing  
Feature
chain  Snurportin-1
EMBL
GDQN01008616    JAT82438.1    AGBW02010519    OWR48356.1    NWSH01000132    PCG79213.1    + More
ODYU01011558    SOQ57370.1    KQ459597    KPI94787.1    KQ460207    KPJ16669.1    AAKN02050765    GFFW01002061    JAV42727.1    AAEX03016332    AAEX03016333    AANG04001761    GL193224    EFB18985.1    ACTA01059787    NEVH01005277    PNF39145.1    KK852989    KDR12791.1    KN120660    KFO37968.1    GACK01007068    JAA57966.1    AK155315    BC049638    BC061258    JL615911    AEH58118.1    GDHF01020029    GDHF01018456    JAI32285.1    JAI33858.1    BC079451    KB031080    ELK03469.1    AMGL01041947    GABZ01006687    JAA46838.1    GEBF01000724    JAO02909.1    AEMK02000056    AQIB01139464    KB572555    EMP27224.1    AF039029    CR456811    AK289475    CH471136    BC004203    JSUE03038753    JSUE03038754    JSUE03038755    JU332393    JU473849    AFE76148.1    AFH30653.1    AJFE02064782    AJFE02064783    AJFE02064784    GABC01007093    NBAG03000345    JAA04245.1    PNI37896.1    AACZ04060370    AK305247    GABF01007439    GABD01006216    BAK62241.1    JAA14706.1    JAA26884.1    BC043630    BC106312    CM004470    AAH43630.1    AAI06313.1    OCT89430.1    JP018546    AES07144.1    AEYP01046648    AEYP01046649    AEYP01046650    GFDF01008657    JAV05427.1    AK054641    BAG51404.1    AGTP01003578    AGTP01003579    BC109999    NDHI03003463    PNJ43415.1    GFWV01001728    MAA26458.1    AAPE02020328    GABE01000318    JAA44421.1    JH880741    ELR59236.1    ACPB03000921    GAMT01004433    GAMS01011197    GAMR01008192    GAMQ01000842    GAMP01008558    JAB07428.1    JAB11939.1    JAB25740.1    JAB41009.1    JAB44197.1    GADI01000307    JAA73501.1    HAAF01008141    CCP79965.1    GEFM01000589    JAP75207.1    GFAA01003211    JAU00224.1    AGCU01107667    AGCU01107668    AGCU01107669    AGCU01107670    AGCU01107671    GGLE01002202    MBY06328.1    AAPE02039582    AQIB01022561    GFPF01011876    MAA23022.1    AHAT01004847    AJWK01017454    ABJB010332325    ABJB010371023    ABJB010500282    ABJB010556892    DS730006    EEC06944.1    UFQS01000126    UFQT01000126    SSX00123.1    SSX20503.1    KE164028    EPQ14679.1    CYRY02036198    VCX15913.1    GEDV01008269    JAP80288.1   
Pfam
PF11538   Snurportin1
Interpro
IPR017336   Snurportin-1        + More
IPR024721   Snurportin-1_N       
IPR002652   Importin-a_IBB       
PDB
3GJX     E-value=3.63561e-48,     Score=483

Ontologies

Topology

Subcellular location
Nucleus  
Cytoplasm   Nucleoplasmic shuttling protein. Its nuclear import involves the nucleocytoplasmic transport receptor importin beta. It is re-exported to the cytoplasm by the XPO1-dependent nuclear export receptor pathway.   With evidence from 1 publications.
Length:
386
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.30362
Exp number, first 60 AAs:
0
Total prob of N-in:
0.02943
outside
1  -  386
 
 

Population Genetic Test Statistics

Pi
309.306149
Theta
223.204177
Tajima's D
1.367996
CLR
0.09267
CSRT
0.755512224388781
Interpretation
Uncertain
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