Gene

KWMTBOMO02651

Annotation

keratinocyte-associated_protein_2_[Bombyx_mori]

Location

Bomo_Chr5(+):7937439-7945101      View in EpiBrowser

Full name

Protein KRTCAP2 homolog      

Alternative Name

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit KCP2

Location in the cell

PlasmaMembrane   Reliability : 4.925

CDS

ATGGCGGTAAACAGTGCCACGTCCTTCGTACTGTCGTCAATATTAACCCTTTTGATATTTTCTGGAATGCAAATGTATAAACCACAGCTTATACTGTCTCCTATGACTATAATATTCGGAGGCTATCTTGGTTCATTAATGTTCATGTTCTTTGTAACTGCTGTTGGTAACCTCGAGACAATTCTGTTTGGTAAAGCATTCCAATTGAAATTACCAGAAGTAGTACTATCGATGGGAATATCATTGATTGCTGCTGGCATGGTCCACAGGATCTGTTTCACCACATGCCTCATTTTTTGCGTGATAACCATTTACTACATGAATAAGTTATCGCAAAAAAAGTATGCGGTAGTTGCCCCTCAACCAGCAGCAGTGAAAAGCCGTCGACACAAATAA

Protein

MAVNSATSFVLSSILTLLIFSGMQMYKPQLILSPMTIIFGGYLGSLMFMFFVTAVGNLETILFGKAFQLKLPEVVLSMGISLIAAGMVHRICFTTCLIFCVITIYYMNKLSQKKYAVVAPQPAAVKSRRHK

Description

Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

Subunit

Component of the oligosaccharyltransferase (OST) complex.

Similarity

Belongs to the KRTCAP2 family.

Keywords

Complete proteome   Membrane   Reference proteome   Transmembrane   Transmembrane helix  

Feature

chain  Protein KRTCAP2 homolog

Uniprot

Q2F5Z2   A0A2A4K6Y5   A0A2H1WBW7   S4P4L3   A0A194PN87   A0A194RGE9   + More
A0A2A4K853   I4DQG3   A0A212FAC7   K7IX77   A0A067R3E8   A0A154PJJ0   A0A3L8D420   A0A158NTB6   A0A195BUP6   A0A151WZK8   A0A1B6DJP1   F4WH27   A0A310SGZ5   A0A195E3Z3   A0A151JVL4   A0A1B6GAD2   A0A0M8ZVW6   A0A162P869   V9IKW4   A0A0P6ILP7   A0A1B6MIM8   A0A0P4X862   A0A2L2Y513   A0A195C8V3   A0A1S3DU69   A0A182TVL1   A0A182XEA6   Q7PQU0   A0A182HJ15   R7VLT3   A0A182LC63   T1IPA8   E9GTX7   A0A1S3H2X6   A0A182VDU6   T1DFH0   E9INX0   A0A087ZY50   V3ZER7   A0A023EFR5   Q1HQF8   B0X587   A0A1Q3F6L2   B0WTH3   A0A182SBQ2   A0A182IPE8   B5X788   A0A0K2UA32   A0A182QR37   A0A131Z5L1   A0A182G9A3   A0A2P8XK01   A0A182PFF8   U5EVW9   A0A182W2U6   A0A182RYD8   A0A182N6R0   A0A2J7QT72   W4YTI3   A0A336MN37   A0A023FMM0   A0A023FUF3   G3MMY0   A0A023GMH8   A0A131XFN4   D6W865   A0A2M3ZE39   A0A2M4C373   A0A224Z5N4   A0A060YNF8   A0A087UPX8   A0A026WZ35   A0A0L8FLB3   B7PWJ5   A0A1L8D9P5   T1ESQ2   A0A1L8D9K1   L7M2Q8   T1E8H7   A0A3M6TVA7   W5JQF7   A0A2M4AIL3   A0A2M4AI10   A0A0K8R4A9   A0A182FAA1   A0A0K8TP07   A7SGC5   Q5Q995   A0A3B3D7B3   A0A3B4F7R8   A0A3P8QFY3   A0A3P9CE75   A0A2M4AFI8   A0A0L7R0N2  

Pubmed

23622113    26354079    22651552    22118469    20075255    24845553    + More
30249741    21347285    21719571    26561354    12364791    14747013    17210077    23254933    20966253    21292972    24330624    21282665    24945155    26483478    17204158    17510324    20433749    26830274    29403074    22216098    28049606    18362917    19820115    28797301    24755649    24508170    25576852    30382153    20920257    23761445    26369729    17615350    16431279    29451363    25186727   

EMBL

DQ311280    ABD36225.1    NWSH01000078    PCG79839.1    ODYU01007628    SOQ50571.1    + More
GAIX01005919    JAA86641.1    KQ459597    KPI94782.1    KQ460207    KPJ16662.1    PCG79840.1    AK404100    BAM20153.1    AGBW02009501    OWR50678.1    AAZX01006551    KK852725    KDR17667.1    KQ434912    KZC11370.1    QOIP01000014    RLU14753.1    ADTU01025732    KQ976409    KYM90933.1    KQ982636    KYQ53318.1    GEDC01011460    JAS25838.1    GL888148    EGI66506.1    KQ769812    OAD52840.1    KQ979701    KYN19584.1    KQ981686    KYN37945.1    GECZ01010384    JAS59385.1    KQ435826    KOX72017.1    LRGB01000512    KZS18613.1    JR049877    AEY61106.1    GDIQ01003648    JAN91089.1    GEBQ01004203    JAT35774.1    GDIP01246823    JAI76578.1    IAAA01004487    IAAA01004488    LAA03261.1    KQ978072    KYM97257.1    AAAB01008879    EAA08316.5    APCN01002115    AMQN01016622    AMQN01016623    KB292244    ELU17885.1    JH431252    GL732565    EFX76933.1    GALA01000602    JAA94250.1    GL764397    EFZ17778.1    KB202567    ESO89643.1    JXUM01069911    GAPW01005907    GAPW01005906    GAPW01005905    GAPW01005904    KQ562578    JAC07691.1    KXJ75559.1    DQ440486    CH477454    DS232371    EDS40733.1    GFDL01011927    JAV23118.1    DS232086    EDS34414.1    BT046907    BT047579    BT047604    ACI66708.1    ACI67380.1    ACI67405.1    HACA01017549    CDW34910.1    AXCN02000061    GEDV01001864    JAP86693.1    JXUM01008425    KQ560260    KXJ83500.1    PYGN01001888    PSN32323.1    GANO01000823    JAB59048.1    NEVH01011198    PNF31790.1    AAGJ04159377    UFQT01001764    SSX31716.1    GBBK01002003    JAC22479.1    GBBL01002266    JAC25054.1    JO843231    AEO34848.1    GBBM01000377    GBBM01000376    JAC35041.1    GEFH01003661    JAP64920.1    KQ971307    EFA10994.1    GGFM01006086    MBW26837.1    GGFJ01010612    MBW59753.1    GFPF01010887    MAA22033.1    FR915089    CDQ93398.1    KK120935    KFM79417.1    KK107061    EZA61320.1    KQ429267    KOF65516.1    ABJB010796665    DS808479    EEC10967.1    GFDF01010888    JAV03196.1    AMQM01001094    KB097143    ESN99002.1    GFDF01010936    JAV03148.1    GACK01006453    JAA58581.1    GAMD01002758    JAA98832.1    RCHS01002836    RMX45353.1    ADMH02000469    ETN66356.1    GGFK01007266    MBW40587.1    GGFK01007041    MBW40362.1    GADI01008105    JAA65703.1    GDAI01001501    JAI16102.1    DS469651    EDO37222.1    AY775809    GGFK01006225    MBW39546.1    KQ414670    KOC64412.1   

Proteomes

UP000218220    UP000053268    UP000053240    UP000007151    UP000002358    UP000027135    + More
UP000076502    UP000279307    UP000005205    UP000078540    UP000075809    UP000007755    UP000078492    UP000078541    UP000053105    UP000076858    UP000078542    UP000079169    UP000075902    UP000076407    UP000007062    UP000075840    UP000014760    UP000075882    UP000000305    UP000085678    UP000075903    UP000005203    UP000030746    UP000069940    UP000249989    UP000008820    UP000002320    UP000075901    UP000075880    UP000087266    UP000075886    UP000245037    UP000075885    UP000075920    UP000075900    UP000075884    UP000235965    UP000007110    UP000007266    UP000193380    UP000054359    UP000053097    UP000053454    UP000001555    UP000015101    UP000275408    UP000000673    UP000069272    UP000001593    UP000261560    UP000261460    UP000265100    UP000265160    UP000053825   

PRIDE

Q2F5Z2    Q5Q995   

Pfam

PF09775   Keratin_assoc

Interpro

IPR018614   KRTCAP2       

ProteinModelPortal

Q2F5Z2   A0A2A4K6Y5   A0A2H1WBW7   S4P4L3   A0A194PN87   A0A194RGE9   + More
A0A2A4K853   I4DQG3   A0A212FAC7   K7IX77   A0A067R3E8   A0A154PJJ0   A0A3L8D420   A0A158NTB6   A0A195BUP6   A0A151WZK8   A0A1B6DJP1   F4WH27   A0A310SGZ5   A0A195E3Z3   A0A151JVL4   A0A1B6GAD2   A0A0M8ZVW6   A0A162P869   V9IKW4   A0A0P6ILP7   A0A1B6MIM8   A0A0P4X862   A0A2L2Y513   A0A195C8V3   A0A1S3DU69   A0A182TVL1   A0A182XEA6   Q7PQU0   A0A182HJ15   R7VLT3   A0A182LC63   T1IPA8   E9GTX7   A0A1S3H2X6   A0A182VDU6   T1DFH0   E9INX0   A0A087ZY50   V3ZER7   A0A023EFR5   Q1HQF8   B0X587   A0A1Q3F6L2   B0WTH3   A0A182SBQ2   A0A182IPE8   B5X788   A0A0K2UA32   A0A182QR37   A0A131Z5L1   A0A182G9A3   A0A2P8XK01   A0A182PFF8   U5EVW9   A0A182W2U6   A0A182RYD8   A0A182N6R0   A0A2J7QT72   W4YTI3   A0A336MN37   A0A023FMM0   A0A023FUF3   G3MMY0   A0A023GMH8   A0A131XFN4   D6W865   A0A2M3ZE39   A0A2M4C373   A0A224Z5N4   A0A060YNF8   A0A087UPX8   A0A026WZ35   A0A0L8FLB3   B7PWJ5   A0A1L8D9P5   T1ESQ2   A0A1L8D9K1   L7M2Q8   T1E8H7   A0A3M6TVA7   W5JQF7   A0A2M4AIL3   A0A2M4AI10   A0A0K8R4A9   A0A182FAA1   A0A0K8TP07   A7SGC5   Q5Q995   A0A3B3D7B3   A0A3B4F7R8   A0A3P8QFY3   A0A3P9CE75   A0A2M4AFI8   A0A0L7R0N2  

KEGG

692887    no KO assigned | (RefSeq) keratinocyte-associated protein 2

GO

GO:0016021   GO:0042543   GO:0005615   GO:0005882  

PANTHER

PTHR32001  

Subcellular location

Membrane  

Length:

131

Number of predicted TMHs:

3

Exp number of AAs in TMHs:

65.84444

Exp number, first 60 AAs:

41.1873

Total prob of N-in:

0.27151

POSSIBLE N-term signal

sequence

outside

1  -  4

TMhelix

5  -  23

inside

24  -  29

TMhelix

30  -  52

outside

53  -  85

TMhelix

86  -  108

inside

109  -  131

 

 

Pi

17.203535

Theta

17.242022

Tajima's D

-0.88322

CLR

1.249171

CSRT

0.16299185040748

Interpretation

Uncertain