Gene

KWMTBOMO02638  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA002644

Annotation

1433Z_BOMMO_RecName:_Full%3D14-3-3_protein_zeta

Location

Bomo_Chr5(+):7682768-7688472      View in EpiBrowser

Full name

14-3-3 protein zeta      

Location in the cell

Cytoplasmic   Reliability : 3.805

CDS

ATGTCCGTCGACAAGGAAGAACTGGTGCAACGTGCCAAATTGGCCGAACAAGCTGAGCGATATGACGACATGGCGGCCGCGATGAAGGAAGTGACGGAAACCGGCGTCGAACTTAGCAACGAGGAGAGGAACCTCCTTTCAGTTGCTTATAAGAATGTCGTAGGTGCCCGACGGTCATCATGGCGTGTCATTTCCTCAATTGAACAGAAAACCGAGGGTTCAGAAAGAAAACAGCAAATGGCAAAAGAATATAGGGTTAAAGTAGAAAAGGAGCTCAGAGAAATCTGCTACGACGTTTTGGGCTTACTTGACAAACACCTAATTCCTAAAGCTAGTAATCCAGAAAGTAAAGTGTTTTACCTCAAAATGAAAGGAGATTACTACAGGTACCTTGCAGAAGTGGCCACAGGAGAAACCAGACATTCTGTTGTAGAGGATTCACAGAAAGCATACCAAGATGCTTTTGAAATCAGCAAGGCGAAAATGCAGCCCACACACCCCATAAGGCTGGGTCTGGCGTTAAATTTCTCAGTCTTTTATTATGAGATATTAAATTCGCCAGACAAGGCGTGTCAACTCGCCAAACAGGCTTTCGACGATGCCATCGCCGAACTGGACACATTGAACGAAGATTCGTACAAAGATTCTACGTTAATAATGCAGTTGCTGCGAGATAACTTGACGCTTTGGACGTCAGACACTCAAGGCGATGGCGACGAGCCTGCCGAGGGCGGCGACAACTAA

Protein

MSVDKEELVQRAKLAEQAERYDDMAAAMKEVTETGVELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTEGSERKQQMAKEYRVKVEKELREICYDVLGLLDKHLIPKASNPESKVFYLKMKGDYYRYLAEVATGETRHSVVEDSQKAYQDAFEISKAKMQPTHPIRLGLALNFSVFYYEILNSPDKACQLAKQAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDTQGDGDEPAEGGDN

Description

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner (By similarity).

Subunit

Homodimer.

Similarity

Belongs to the 14-3-3 family.

Keywords

Complete proteome   Cytoplasm   Reference proteome  

Feature

chain  14-3-3 protein zeta

Uniprot

B2ZZW1   W6FIX9   Q2F637   A0A0K0PMJ0   V9P4T4   A0A2W1BFL3   + More
C4NFK6   W6FFT8   A0A068JLL8   A0A0A0R1S8   A0A059P9Y8   W6FHK2   W6FHJ9   I4DM30   I4DIK6   S4NT22   A0A3G1T195   C5MQF2   A0A2A4K7E8   A0A2J7QM22   A0A1V1FIV6   G9I554   A0A0J7L788   G9I534   A0A1B6GU84   A0A3L8DQ47   A0A1B6HAK2   G9I556   G9I558   W6FHJ1   G9I542   V9I8Q3   A0A1D1YYN0   G9I536   G9I539   A0A0C9RFG6   G9I551   A0A191UR54   G9I545   G9I537   G9I540   R4WCX1   G9I552   G9I555   G9I535   A0A1B6D515   A0A0A9Z0T5   D2XRB2   G9I543   B6REW6   A0A224XRB0   A0A0V0G2Q7   A0A171BC03   A0A069DQN5   D1FQ28   A0A195EX62   G9I559   A0A0P6A896   E9H1W5   A0A0P4VRR1   R4G5D9   G9I557   A0A1Y1MYB5   A0A1B6F780   G9I544   G9I538   G9I541   A0A0C9RAT9   A0A023GGR3   A0A224YG03   A0A131YQJ3   A0A023FIS9   L7M1Q0   A0A023FVN8   A0A293N177   A0A1Z5L684   A0A131XJS0   A0A034WTY5   A0A1E1XFY3   V5HMU2   W6FIW7   W6FTC6   W6FTC9   W6FFT2   W6FG77   W6FFS7   A0A2M3ZFD4   W6FG76   W6FHI9   A0A2M4A313   W6FHI3   W5JWE7   C1JLF2   A0NBC2   W6FIV7   A0A2R5LA44   G9I553   A0A1B6I403   A0A1Q3FJ42   G9I546  

Pubmed

18462820    28756777    19442669    24747013    22651552    23622113    + More
28410430    30249741    21347285    27538518    27142481    23691247    25401762    26823975    26334808    21292972    27129103    28004739    28797301    26830274    25576852    28528879    28049606    24762651    28503490    25765539    20920257    23761445    12364791    14747013    17210077   

EMBL

AB378097    BAG38533.1    KF887480    AHJ25958.1    EF210316    DQ311235    + More
KP198607    AKQ44386.1    KC188794    AGT99003.1    KZ150098    PZC73578.1    FJ550359    ACR07788.1    KF887472    AHJ25950.1    KF640688    AIE17714.1    KM027250    AIU94619.1    JQ284433    AFV09942.1    KF887481    AHJ25959.1    KF887476    AHJ25954.1    AK402348    BAM18970.1    AK401124    BAM17746.1    GAIX01013822    JAA78738.1    MG846902    AXY94754.1    GQ131301    ACS12990.1    NWSH01000078    PCG79858.1    NEVH01013227    PNF29627.1    FX985371    BAX07384.1    JN571282    AEW70350.1    LBMM01000400    KMQ98443.1    JN571274    AEW70330.1    GECZ01019550    GECZ01012628    GECZ01003793    JAS50219.1    JAS57141.1    JAS65976.1    QOIP01000006    RLU21958.1    GECU01036024    GECU01026372    GECU01006134    GECU01003396    JAS71682.1    JAS81334.1    JAT01573.1    JAT04311.1    JN571283    AEW70352.1    JN571284    AEW70354.1    KF887466    AHJ25944.1    JN571277    AEW70338.1    JR036918    AEY57470.1    GDJX01008192    JAT59744.1    JN571275    AEW70332.1    JN571276    AEW70335.1    GBYB01011857    JAG81624.1    JN571281    AEW70347.1    KU365942    KU932325    ANJ04658.1    APA33961.1    JN571278    AEW70341.1    AEW70333.1    AEW70336.1    AK417014    BAN20229.1    AEW70348.1    AEW70351.1    AEW70331.1    GEDC01028190    GEDC01016562    GEDC01004511    JAS09108.1    JAS20736.1    JAS32787.1    GBHO01008182    GBHO01008180    GBHO01008179    GBRD01017845    GBRD01017844    GBRD01015945    GDHC01006422    JAG35422.1    JAG35424.1    JAG35425.1    JAG47982.1    JAQ12207.1    GU244586    ADB03180.1    AEW70339.1    EU188753    ABX80390.1    GFTR01004078    JAW12348.1    GECL01003706    JAP02418.1    GEMB01000007    JAS03100.1    GBGD01002674    JAC86215.1    EZ419928    ACZ28283.1    KQ981953    KYN32469.1    AEW70355.1    GDIP01037914    LRGB01001794    JAM65801.1    KZS10465.1    KF887483    GL732584    AHJ25961.1    EFX74245.1    GDKW01000841    JAI55754.1    ACPB03011888    GAHY01000635    JAA76875.1    AEW70353.1    GEZM01021555    GEZM01021554    JAV88946.1    GECZ01023667    JAS46102.1    AEW70340.1    AEW70334.1    AEW70337.1    GBYB01003961    JAG73728.1    GBBM01002271    JAC33147.1    GFPF01005471    MAA16617.1    GEDV01007699    JAP80858.1    GBBK01003458    JAC21024.1    GACK01007049    JAA57985.1    GBBL01001753    JAC25567.1    GFWV01021213    MAA45941.1    GFJQ02004054    JAW02916.1    GEFH01001774    JAP66807.1    GBBR01000041    JAC59021.1    GFAC01000974    JAT98214.1    GADI01006724    GANP01007636    GEFM01004495    JAA67084.1    JAB76832.1    JAP71301.1    KF887465    AHJ25943.1    KF887454    AHJ25932.1    KF887459    AHJ25937.1    KF887462    AHJ25940.1    KF887468    AHJ25946.1    KF887457    AHJ25935.1    GGFM01006462    MBW27213.1    KF887463    AHJ25941.1    KF887461    AHJ25939.1    GGFK01001856    MBW35177.1    KF887451    AHJ25929.1    KF887455    ADMH02000160    GGFL01004210    AHJ25933.1    ETN67535.1    MBW68388.1    FJ687751    KF887467    ACN69053.1    AHJ25945.1    AAAB01008807    EAL41737.1    EDO64520.1    KF887450    AHJ25928.1    GGLE01002233    MBY06359.1    AEW70349.1    GECU01026038    JAS81668.1    GFDL01007523    JAV27522.1    AEW70342.1   

Proteomes

UP000005204    UP000218220    UP000235965    UP000036403    UP000279307    UP000005205    + More
UP000078541    UP000076858    UP000000305    UP000015103    UP000000673    UP000007062    UP000069272   

PRIDE

Q2F637    C4NFK6    G9I534    G9I556    G9I558    G9I542    + More
G9I539    G9I551    G9I545    D2XRB2    B6REW6    D1FQ28    E9H1W5   

Pfam

PF00244   14-3-3

Interpro

IPR023410   14-3-3_domain        + More
IPR000308   14-3-3       
IPR036815   14-3-3_dom_sf       
IPR023409   14-3-3_CS       

SUPFAM

SSF48445   SSF48445       

Gene 3D

1.20.190.20    

ProteinModelPortal

B2ZZW1   W6FIX9   Q2F637   A0A0K0PMJ0   V9P4T4   A0A2W1BFL3   + More
C4NFK6   W6FFT8   A0A068JLL8   A0A0A0R1S8   A0A059P9Y8   W6FHK2   W6FHJ9   I4DM30   I4DIK6   S4NT22   A0A3G1T195   C5MQF2   A0A2A4K7E8   A0A2J7QM22   A0A1V1FIV6   G9I554   A0A0J7L788   G9I534   A0A1B6GU84   A0A3L8DQ47   A0A1B6HAK2   G9I556   G9I558   W6FHJ1   G9I542   V9I8Q3   A0A1D1YYN0   G9I536   G9I539   A0A0C9RFG6   G9I551   A0A191UR54   G9I545   G9I537   G9I540   R4WCX1   G9I552   G9I555   G9I535   A0A1B6D515   A0A0A9Z0T5   D2XRB2   G9I543   B6REW6   A0A224XRB0   A0A0V0G2Q7   A0A171BC03   A0A069DQN5   D1FQ28   A0A195EX62   G9I559   A0A0P6A896   E9H1W5   A0A0P4VRR1   R4G5D9   G9I557   A0A1Y1MYB5   A0A1B6F780   G9I544   G9I538   G9I541   A0A0C9RAT9   A0A023GGR3   A0A224YG03   A0A131YQJ3   A0A023FIS9   L7M1Q0   A0A023FVN8   A0A293N177   A0A1Z5L684   A0A131XJS0   A0A034WTY5   A0A1E1XFY3   V5HMU2   W6FIW7   W6FTC6   W6FTC9   W6FFT2   W6FG77   W6FFS7   A0A2M3ZFD4   W6FG76   W6FHI9   A0A2M4A313   W6FHI3   W5JWE7   C1JLF2   A0NBC2   W6FIV7   A0A2R5LA44   G9I553   A0A1B6I403   A0A1Q3FJ42   G9I546  

PDB

4HKC     E-value=6.46615e-101,     Score=936

KEGG

692854    K16197 14-3-3 protein beta/theta/zeta | (RefSeq) 14-3-3zeta, Ywhaz; 14-3-3 protein zeta

PATHWAY

04013    MAPK signaling pathway - fly - Bombyx mori (domestic silkworm)
04391    Hippo signaling pathway - fly - Bombyx mori (domestic silkworm)

GO

GO:0019904   GO:0005737   GO:0005622   GO:0042254   GO:0016021   GO:0006812   GO:0015299   GO:0006631   GO:0006635   GO:0006281   GO:0048384  

PANTHER

PTHR18860  

Subcellular location

Cytoplasm  

Length:

247

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.07666

Exp number, first 60 AAs:

0

Total prob of N-in:

0.04475

outside

1  -  247

 

 

Pi

261.786741

Theta

204.529105

Tajima's D

0.677144

CLR

0.030324

CSRT

0.565521723913804

Interpretation

Uncertain