Gene

KWMTBOMO02615

Pre Gene Modal

BGIBMGA002632

Annotation

PREDICTED:_queuine_tRNA-ribosyltransferase_subunit_QTRTD1_homolog_[Amyelois_transitella]

Location

Bomo_Chr5(+):7126058-7132956      View in EpiBrowser

Full name

Queuine tRNA-ribosyltransferase accessory subunit 2      

Alternative Name

Queuine tRNA-ribosyltransferase domain-containing protein 1

Location in the cell

Cytoplasmic   Reliability : 1.881 Mitochondrial   Reliability : 1.472

CDS

ATGCGCTTTAATATTAAACAAGTAAACTGTGGTAGTGAACGCATTGGCTCTTTAACAGGATTTATTAAATCATCTAAAACTATTATTGAAACTCCAACTGCCGCCTTATTGACTCAGGGGTGCAGTGTAGTTCATCTGACAGCTGAAGTGTTAGCTAAAGTATTCCCTGATACACAATTACTATGGCTCCCACTATCCAACTCAGTTCAATTAGAAAATGGAGTAAAAGCCCAAGGAGAAGGTGTTGCAAAGTTTGCTGGATTACCGAAACATGTAATATGTGCGACTTTATATAACATAAATGAAATAGTTCCACCTGGGCATTTTGAACTAGGCAAATTGCCACTTTGGACTAAGAATGGAAAGAAAATGATAACTGCAGATAAATATATGGATTTAATGGAGACATTTAAACCTGATATAATTTTAGCTGCTTCAGATGGACGTATCTCTCTAAATGAAAAACCAAAAAGAATTGTCAAGTCTGTAGAGAGGACAATGGCTTTGCTTGATTCATGCATAAATAAATATAAAGCTTCTGAAGAACTTCAACAAAGCTCACTTGTAGGTGTGATAGTTGCTGCGAACATACCACATAAATGTGAGGAATGCATCCGACATATCCTGAAATACAAAGAAACATTAGTTGGAGTTGCATTAGCTGGTCTTACTGATGGAAGCAAGGAGTCATATGAAGTTTCTCTTGATAAGCTGAAAGAAATATTCAGTAGAGTTGGTGGCTCACTACCAAATGATCTACTTCGTATTGTTGAAGGTTCTTGGAATCCTGCAGTCATAGTAACAGCAATAGAGCATGGTTGGGATGTGTTTGATGGTTCATATCCAATAAAACTCACAAATAAGGGACATGCATTGTCTTTAAATTTTGATGTGTATCGATATAGTGGAGATCCATGTATCATGGACCTTAATGACATTAGGTATAATGAAGATTTCAAACCTATACTGGAAGGATGCGAATGTTTGACATGTAAAAAACACACACGTGCATATATTAGGCATCTTTTAAATACAAGAGAGATGCTGGCATCTGTTTTGTTGAGCATACACAATCTACATCATTTCAATGAATTCTTCGTGCAAGCTCGTCTACACATCAGCGCCTCTACGTTCAATATTTACAAGAAACACATTATAACACAATATGAAAATATAAATCCGAAATTGGATAATGAAGAAGACAAGACAGCTCCAACTCTTGTGCAGGATAAAAAGAAAATTAAAGTGAGAATTGGTGATAATGTCAAGACTGAAGTTAATGGTACAATTATAAAGTAG

Protein

MRFNIKQVNCGSERIGSLTGFIKSSKTIIETPTAALLTQGCSVVHLTAEVLAKVFPDTQLLWLPLSNSVQLENGVKAQGEGVAKFAGLPKHVICATLYNINEIVPPGHFELGKLPLWTKNGKKMITADKYMDLMETFKPDIILAASDGRISLNEKPKRIVKSVERTMALLDSCINKYKASEELQQSSLVGVIVAANIPHKCEECIRHILKYKETLVGVALAGLTDGSKESYEVSLDKLKEIFSRVGGSLPNDLLRIVEGSWNPAVIVTAIEHGWDVFDGSYPIKLTNKGHALSLNFDVYRYSGDPCIMDLNDIRYNEDFKPILEGCECLTCKKHTRAYIRHLLNTREMLASVLLSIHNLHHFNEFFVQARLHISASTFNIYKKHIITQYENINPKLDNEEDKTAPTLVQDKKKIKVRIGDNVKTEVNGTIIK

Description

Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).

Cofactor

Zn(2+)

Subunit

Heterodimer of a catalytic subunit and an accessory subunit.
Heterodimer of a catalytic subunit QTRT1 and an accessory subunit QTRT2.

Similarity

Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.

Keywords

Complete proteome   Cytoplasm   Metal-binding   Reference proteome   tRNA processing   Zinc  

Feature

chain  Queuine tRNA-ribosyltransferase accessory subunit 2

Uniprot

H9IZE7   A0A2A4J5J8   A0A2H1X3A8   A0A212F4W8   A0A194PVW4   A0A194R366   + More
A0A154P1D3   A0A1Q3EX16   A0A088AU00   A0A2A3E474   A0A310S9P4   A0A195CUI5   Q16RF5   A0A151IW26   D6WEE4   A0A026W5Z6   B0WAN0   A0A0N0BIK9   A0A0L7QZU4   A0A195FNM8   A0A151XFS5   K7IW16   E2BPE5   A0A182S4P4   A0A232FP34   A0A1B6L868   A0A2M4ANY7   A0A182MR31   A0A182XUF8   A0A2M4ANU4   U5ETL9   A0A182WKD4   A0A182GIG0   A0A210PLW6   A0A1W4X034   Q7Q727   A0A0A9WJF6   A0A182UCV7   E9IEU6   A0A158NQ06   A0A1Y1NHD0   A0A182UPJ9   A0A2C9GQQ2   A0A182K0P3   A0A195BI33   A0A1B6IY77   W5J666   A0A336M3I6   J3JXK0   A0A182NM30   A0A182Y111   A0A182PP46   E2AWM1   E0W0V4   A0A2H8THW8   A0A1J1I6B2   A0A182FH26   A0A0K8TML0   X1WJC8   A0A182QNR0   A0A146M3W4   A0A2C9KGN1   A0A2T7NKS3   A0A2C9KGL2   A0A1L8DGP7   A0A2R5LBW5   W8C340   A0A224YXE9   A0A084WKJ8   A0A2S2QDK0   A0A0L0C5S9   A0A1I8NVM9   A0A0K8UCF5   A0A131YJ59   K7F3D9   U3I0U4   A0A034VRY4   A0A3B4US70   A0A3B4WTW3   B4KXI8   A0A0A1XFN4   A0A0A1WLF7   T1HU78   A0A1S3K869   A0A1S3KCW3   A0A182IUZ4   A0A0A1WDT9   A0A1A9UG18   A0A3B5AI14   E9GAK2   M4A6M3   A0A3P8TVV2   A0A0P5Y9Q7   B4LFW2   A0A1A9ZKG9   A0A2P6KLD4   A0A1S2ZAG8   A0A3B5LPB1   D3TNW9  

Pubmed

19121390    22118469    26354079    17510324    18362917    19820115    + More
24508170    30249741    20075255    20798317    28648823    26483478    28812685    12364791    25401762    21282665    21347285    28004739    20920257    23761445    22516182    23537049    25244985    20566863    26369729    26823975    15562597    24495485    28797301    24438588    26108605    26830274    17381049    23749191    25348373    17994087    25830018    21292972    23542700    20353571   

EMBL

BABH01014180    BABH01014181    BABH01014182    BABH01014183    NWSH01003102    PCG66948.1    + More
ODYU01013062    SOQ59726.1    AGBW02010305    OWR48763.1    KQ459589    KPI97526.1    KQ460870    KPJ11685.1    KQ434783    KZC04940.1    GFDL01015186    JAV19859.1    KZ288721    PBC26082.1    KQ762864    OAD55400.1    KQ977279    KYN04320.1    CH477712    KQ980880    KYN12009.1    KQ971318    EFA00359.1    KK107388    QOIP01000001    EZA51490.1    RLU26763.1    DS231873    KQ435729    KOX77698.1    KQ414676    KOC64082.1    KQ981382    KYN42063.1    KQ982182    KYQ59239.1    GL449633    EFN82349.1    NNAY01000002    OXU32290.1    GEBQ01020253    JAT19724.1    GGFK01009170    MBW42491.1    AXCM01005810    GGFK01009124    MBW42445.1    GANO01002720    JAB57151.1    JXUM01011978    JXUM01011979    KQ560342    KXJ82951.1    NEDP02005589    OWF37471.1    AAAB01008960    GBHO01036996    GBHO01015945    GBHO01015941    GBHO01006313    JAG06608.1    JAG27659.1    JAG27663.1    JAG37291.1    GL762722    EFZ20877.1    ADTU01022843    GEZM01007533    GEZM01007532    JAV95107.1    APCN01004280    KQ976464    KYM84485.1    GECU01015833    JAS91873.1    ADMH02002078    ETN59481.1    UFQT01000501    SSX24805.1    APGK01030338    BT127969    KB740770    KB632132    AEE62931.1    ENN78990.1    ERL88993.1    GL443346    EFN62185.1    DS235862    EEB19260.1    GFXV01001053    MBW12858.1    CVRI01000038    CRK93937.1    GDAI01002212    JAI15391.1    ABLF02036150    ABLF02036152    AXCN02002327    GDHC01004500    JAQ14129.1    PZQS01000011    PVD21751.1    GFDF01008455    JAV05629.1    GGLE01002820    MBY06946.1    GAMC01006259    JAC00297.1    GFPF01011150    MAA22296.1    ATLV01024123    KE525349    KFB50742.1    GGMS01006613    MBY75816.1    JRES01000850    KNC27748.1    GDHF01028068    JAI24246.1    GEDV01009560    JAP78997.1    AGCU01013677    AGCU01013678    ADON01077996    ADON01077997    GAKP01014639    GAKP01014638    JAC44313.1    CH933809    GBXI01004541    JAD09751.1    GBXI01014967    JAC99324.1    ACPB03000715    GBXI01017123    JAC97168.1    GL732537    EFX83257.1    GDIP01074514    LRGB01002019    JAM29201.1    KZS09606.1    CH940647    MWRG01009342    PRD27140.1    CCAG010019566    EZ423121    ADD19397.1   

Proteomes

UP000005204    UP000218220    UP000007151    UP000053268    UP000053240    UP000076502    + More
UP000005203    UP000242457    UP000078542    UP000008820    UP000078492    UP000007266    UP000053097    UP000279307    UP000002320    UP000053105    UP000053825    UP000078541    UP000075809    UP000002358    UP000008237    UP000075900    UP000215335    UP000075883    UP000076407    UP000075920    UP000069940    UP000249989    UP000242188    UP000192223    UP000007062    UP000075902    UP000005205    UP000075903    UP000075840    UP000075881    UP000078540    UP000000673    UP000019118    UP000030742    UP000075884    UP000076408    UP000075885    UP000000311    UP000009046    UP000183832    UP000069272    UP000007819    UP000075886    UP000076420    UP000245119    UP000030765    UP000037069    UP000095300    UP000007267    UP000016666    UP000261420    UP000261360    UP000009192    UP000015103    UP000085678    UP000075880    UP000078200    UP000261400    UP000000305    UP000002852    UP000265080    UP000076858    UP000008792    UP000092445    UP000079721    UP000261380    UP000092444   

PRIDE

H9IZE7   

Pfam

PF01702   TGT        + More
PF00899   ThiF
PF14523   Syntaxin_2
PF05739   SNARE

Interpro

IPR036691   Endo/exonu/phosph_ase_sf        + More
IPR036511   TGT-like_sf       
IPR028592   QTRTD1       
IPR002616   tRNA_ribo_trans-like       
IPR010989   SNARE       
IPR035985   Ubiquitin-activating_enz       
IPR000594   ThiF_NAD_FAD-bd       
IPR006011   Syntaxin_N       
IPR000727   T_SNARE_dom       

SUPFAM

SSF56219   SSF56219        + More
SSF51713   SSF51713       
SSF69572   SSF69572       
SSF47661   SSF47661       

Gene 3D

3.20.20.105     3.60.10.10    

ProteinModelPortal

H9IZE7   A0A2A4J5J8   A0A2H1X3A8   A0A212F4W8   A0A194PVW4   A0A194R366   + More
A0A154P1D3   A0A1Q3EX16   A0A088AU00   A0A2A3E474   A0A310S9P4   A0A195CUI5   Q16RF5   A0A151IW26   D6WEE4   A0A026W5Z6   B0WAN0   A0A0N0BIK9   A0A0L7QZU4   A0A195FNM8   A0A151XFS5   K7IW16   E2BPE5   A0A182S4P4   A0A232FP34   A0A1B6L868   A0A2M4ANY7   A0A182MR31   A0A182XUF8   A0A2M4ANU4   U5ETL9   A0A182WKD4   A0A182GIG0   A0A210PLW6   A0A1W4X034   Q7Q727   A0A0A9WJF6   A0A182UCV7   E9IEU6   A0A158NQ06   A0A1Y1NHD0   A0A182UPJ9   A0A2C9GQQ2   A0A182K0P3   A0A195BI33   A0A1B6IY77   W5J666   A0A336M3I6   J3JXK0   A0A182NM30   A0A182Y111   A0A182PP46   E2AWM1   E0W0V4   A0A2H8THW8   A0A1J1I6B2   A0A182FH26   A0A0K8TML0   X1WJC8   A0A182QNR0   A0A146M3W4   A0A2C9KGN1   A0A2T7NKS3   A0A2C9KGL2   A0A1L8DGP7   A0A2R5LBW5   W8C340   A0A224YXE9   A0A084WKJ8   A0A2S2QDK0   A0A0L0C5S9   A0A1I8NVM9   A0A0K8UCF5   A0A131YJ59   K7F3D9   U3I0U4   A0A034VRY4   A0A3B4US70   A0A3B4WTW3   B4KXI8   A0A0A1XFN4   A0A0A1WLF7   T1HU78   A0A1S3K869   A0A1S3KCW3   A0A182IUZ4   A0A0A1WDT9   A0A1A9UG18   A0A3B5AI14   E9GAK2   M4A6M3   A0A3P8TVV2   A0A0P5Y9Q7   B4LFW2   A0A1A9ZKG9   A0A2P6KLD4   A0A1S2ZAG8   A0A3B5LPB1   D3TNW9  

PDB

6FV5     E-value=1.04338e-44,     Score=454

KEGG

101735398    K15407 queuine tRNA-ribosyltransferase subunit QTRTD1 [EC:2.4.2.29] | (RefSeq) queuine tRNA-ribosylt

GO

GO:0008479   GO:0101030   GO:0005737   GO:0046872   GO:0016763   GO:0006400   GO:0019781   GO:0016192   GO:0016021   GO:0045116   GO:0016020   GO:0032991   GO:0005741   GO:0046982   GO:0042803   GO:0008616   GO:0043565   GO:0005515   GO:0006631   GO:0006635   GO:0006281   GO:0048384  

Subcellular location

Cytoplasm  
Mitochondrion outer membrane   May associate with the mitochondrion outer membrane.   With evidence from 1 publications.

Length:

432

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0452100000000001

Exp number, first 60 AAs:

0.03002

Total prob of N-in:

0.02621

outside

1  -  432

 

 

Pi

316.993245

Theta

182.745793

Tajima's D

1.74839

CLR

0.571294

CSRT

0.835808209589521

Interpretation

Uncertain