Gene

KWMTBOMO02573

Annotation

reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr5(-):5936608-5941476      View in EpiBrowser

Full name

Probable RNA-directed DNA polymerase from transposon BS       + More
Probable RNA-directed DNA polymerase from transposon X-element      

Alternative Name

Reverse transcriptase

Location in the cell

Nuclear   Reliability : 2.696

CDS

ATGCACAGCGGTCGCGATAAATTCGCGTACGATATGGTGCTCGTAGCACTAGAAGCCACACCGGAGGGCAAGAAAATTGCCTCATGTCTCCGCACCGTGTGCGGCCTATCGGGGGTCACCGTAGAGGCCCCCTACAAACGCGGCACTCCCGGGCAGTGCCACCGTTGCCAATTATATGGCCACTCCGCGCGTAACTGCAACGCGCGACCGCGTTGCGTGAAATGTTTAGACGATCACGCGACCACCGATTGCTCGCGCGTGAAGGAGACAGCAACGGAGCCGCCGAGCTGTGTACTCTGCCGCAAGCAGGGACACACGGCCAACTACCGTGGATGCCCCAAGGCTCCACGGAAGCGCCCGGCAAACGCGCCCCCTAAAACCGCTGGCCCAAAGACTTCGGCGCCCCGCGCGCCGAAACCGGCTTTCGTACCGGCTCCGGTGCCCACCGTCTCCGCGTGGGCGAAACCGTTGCCGTTCACGAAGGCAGGAACGACACCGGCACCCCAACCGCGGTACGCGCCGCAACCTCTACTCGCGCCGCGCCCCGTCCCCGCGCCCGCGCCCGGTCCCGCGCCTCGCCCCGGCCCCGCGCACTCAAACGATTTTACAATTATTCGCGACTACATCGCCGCGATAAACATCGACCGCATGCGTGCGTTCGCCGACGCCATGCGCAGAGCGGTCACGGCCGAAGACCGCCTAAACGCGACGTTCGAGTACATCGACGTCATCGAGTCCGTCCAGCGCACGCTGCGCGATCAAGTATATGAGTTTCTCCGCGATAATCTCATCGACATCCTTCTGGTGCAGGAGACCTTCCTAAAGCCCTCGCGTCGCGACCCCAAAGTCGCGAACTACGTCATGGTTAGGAATGACAGACTCTCCGCCCGCAAGGGCGGGACTGTCATTTACTATAGGAGGGCCCTGCACTGCGTCCCTCTCGATACTCCCTCGCTCTTACATATCGAGGCGTCAGTGTGCCGCATCGCGCTGACGGGACACCAGCCGATCGTCATCGCATCCGTTTATCTCCCCCCTGACAAACCCCTCCTGAGCAGTGACCTCGAGACACTGTTCGGTATGGGGGACGCGGTCATCCTGGCAGGCGATTTAAATTGCCACCACACTAGGTGGAACTGCCATCGCACGAATGTGAACGGTAGGCGTCTCGACGCGTTCATAGACGACCTCACATTCGAAGTATTCAACCCCCCGACCCCCACGTGCTATCCGTACAACGCCGCGCGTCGTCCGAGCACAATAGATCTGGCACTGCTGAGGAACGTAACTCTGCGCTTGCGCTCCATCGAGGCAATGTCAGAACTCGACTCAGACCACCGACCTGTCGTCATGCAGCTCGGTCGCCCACTCAACCGCGAACCAGATACGAGGACCATGGTGGATTGGAAGAAGCTGGGCACGTGCTTAGCTGACACCGCTCCACCAATCCTCCCTTGCGGCCCGGATTCAACTCCATCCCCCGAGGATACCGTCGAATCCATAAACATCTTCACTGATCACGTCTCGACGGCGATCATAAGATCCTCGAAACAAGTCGATGTGGAGGACTGCTTCCACCGCATCAGACTTTCCCCCGAACTTAGGGACCTAGTTAGAATTAGAAACGCGGCAATCCGGGCCTACGATCGATATCCCACGGATTCAAACCGGACTCGGATGCGTCGCTTACAGCGGGAGGTCAAATCCCGCTTAAGCGACGCCCGAAACGAAAACTGGGATAGTTATTTAGAAGAACTCGCGCCCACTCACCAAGCATACTGGCAACTAGCTAGGACCCTCAAGTCCGAAACTATAGCCACTATGCCGCCTCTCGTACGCCCCTCAGGCCAACCACCGGCTTACGATGACGATGACAAGGCAGAGTTGCTGGCCGATACACTGCAAGAGCAGTGCACCACCAGCACTCAACACGCGGACCCCGAACACACCGAGTTCGTCGACAGGGAGGTCGAGCGCAGAGCTTCCCTGCCGCCCTCGGACGCGTTACCCCCCATTACCACTTCCGAGGTCAAGGAGGCGATCGATAGCCTACAACCACGGAAAGCTCCCGGCTCCGACGGCATCCGCAACCGCGCGCTTAAATTGTTACCAGCCCAACTGATAACGATGTTGGCCACCATATTAAATGCTGCTATGACGAACTGCATCTTTCCCGCGGCGTGGAAAGAAGCGGACGTTATCGGCATACACAAGCCGGGCAAACCGAAGAACGAAACCGCGAGTTACCGCCCCATCAGTCTCCTCCCGGCGATAGGCAAACTATACGAACGACTCCTTCGTAAACGCCTCTGGGACTTCGTATCCGCGAACAAAATTCTGATAGACGAGCAGTTTGGATTCCGCGCCAGACACTCGTGCGTCCATCAAGTGCACCGCCTCACGGAGCACATCTTACTAGGGCTGAACAGGCGGAAACCCATTCCGACAGGAGCCCTCTTCTTCGATATAGCGAAGGCGTTCGACAAAGTCTGGCACAACGGTTTGATATACAAACTGTATAACATGGGAGTGCCAGACAGACTCGTGCTCATCATACGAGACTACTTGTCGAACCGTTCGTTCCGATATCGAGTCGAGGGAACGCGTTCCCGGCCCCGTCACGTCACAGCCGGAGTCCCGCAAGGCTCCGCCCTCTCCCCGTTACTATTCAGTTTGTATATCAATGATATACCCCGGTCTCCGGAGACCCATCTGGCGCTCTTCGCCGATGACACCGCCATCTACTACTCGTGTAGGAAGAAGGCGTTGCTTCATCGACGACTTCAGACCGCGGCTACCACCATGGGACAGTGGTTCCGGAAGTGGCGCATCGACATCAACCCCACGAAAAGCACAGCGGTGCTCTTCAAAAGGGGTCGCCCTCCGAACACCACGCTGAGCATCCCTCTCCCGACTAGGCGCGTCAATAACCCCGCCCCCGCCGTTCGCCCAATCACGATGTTCGACCAGCCCATACCGTGGGCCCCGAAGGTCAAATATTTAGGCGTCACCCTCGACAGTAGGATGACATTCCGCCCCCACATCAAGACGGTACGCGACCGTGCCGCCTTCATTCTAGGACGTCTCTACCCGATGATATGTAGGCGAAGTAAAATGTCCCTTAGAAATAAGGTGACACTCTACAAAACTTGCATACGCCCCGTCATGACCTATGCAAGTGTAGTGTTCGCTCACGCGGCCCGCATACACTTAAAATCCTTTCAAATTATTCAATCCCGTTTTTGCAGGATAGCCGTCGGAGCCCCGTGGTTCGTCAGGAACGTCGACCTCCATGACGACCTGGACTTAGAGTCCATCAGTAAGTATCTTCAGTCGGCGTCCATGCGCCACTTCGATAAAGCGGCACGACACGAGAACCCTCTCATCGTGGCCGCCGGTAACTACATTCCCGATCCTGCGGACAGAATGGAAAGCAGTCGACGTCGCCCTAAACACGTCATCTCGGATCCTCCTGATCCACTAACGGTGCTTTTAGAGAAAGACGCCCGTGACTATGAATAA

Protein

MHSGRDKFAYDMVLVALEATPEGKKIASCLRTVCGLSGVTVEAPYKRGTPGQCHRCQLYGHSARNCNARPRCVKCLDDHATTDCSRVKETATEPPSCVLCRKQGHTANYRGCPKAPRKRPANAPPKTAGPKTSAPRAPKPAFVPAPVPTVSAWAKPLPFTKAGTTPAPQPRYAPQPLLAPRPVPAPAPGPAPRPGPAHSNDFTIIRDYIAAINIDRMRAFADAMRRAVTAEDRLNATFEYIDVIESVQRTLRDQVYEFLRDNLIDILLVQETFLKPSRRDPKVANYVMVRNDRLSARKGGTVIYYRRALHCVPLDTPSLLHIEASVCRIALTGHQPIVIASVYLPPDKPLLSSDLETLFGMGDAVILAGDLNCHHTRWNCHRTNVNGRRLDAFIDDLTFEVFNPPTPTCYPYNAARRPSTIDLALLRNVTLRLRSIEAMSELDSDHRPVVMQLGRPLNREPDTRTMVDWKKLGTCLADTAPPILPCGPDSTPSPEDTVESINIFTDHVSTAIIRSSKQVDVEDCFHRIRLSPELRDLVRIRNAAIRAYDRYPTDSNRTRMRRLQREVKSRLSDARNENWDSYLEELAPTHQAYWQLARTLKSETIATMPPLVRPSGQPPAYDDDDKAELLADTLQEQCTTSTQHADPEHTEFVDREVERRASLPPSDALPPITTSEVKEAIDSLQPRKAPGSDGIRNRALKLLPAQLITMLATILNAAMTNCIFPAAWKEADVIGIHKPGKPKNETASYRPISLLPAIGKLYERLLRKRLWDFVSANKILIDEQFGFRARHSCVHQVHRLTEHILLGLNRRKPIPTGALFFDIAKAFDKVWHNGLIYKLYNMGVPDRLVLIIRDYLSNRSFRYRVEGTRSRPRHVTAGVPQGSALSPLLFSLYINDIPRSPETHLALFADDTAIYYSCRKKALLHRRLQTAATTMGQWFRKWRIDINPTKSTAVLFKRGRPPNTTLSIPLPTRRVNNPAPAVRPITMFDQPIPWAPKVKYLGVTLDSRMTFRPHIKTVRDRAAFILGRLYPMICRRSKMSLRNKVTLYKTCIRPVMTYASVVFAHAARIHLKSFQIIQSRFCRIAVGAPWFVRNVDLHDDLDLESISKYLQSASMRHFDKAARHENPLIVAAGNYIPDPADRMESSRRRPKHVISDPPDPLTVLLEKDARDYE

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Miscellaneous

At least 30 copies of X-element are present in the genome and some elements are polymorphic between different strains.

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  Probable RNA-directed DNA polymerase from transposon BS

Uniprot

Q93137   Q9XXW0   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
A0A139W8G9   A0A139WA11   V5GNJ2   V5GNF3   A0A023EYS8   A0A023EZE6   X1WLB2   Q07995   A0A2S2QEE0   A0A2S2PPK8   A0A3N5Z7I3   A0A2S2Q383   A0A2M4CV52   A0A2M4CV42   A0A2J7R7D0   X1WNI2   A0A224XB44   A0A2S2NGV8   X1WZH0   A0A224X6Q4   A0A2M4BD67   A0A2J7QR37   A0A2M4BDV6   A0A2M4BD66   A0A2M4BDA5   A0A2J7PBY3   A0A2M4BD62   A0A087UGF5   A0A2J7QY69   A0A224X6S1   J9LC21   A0A224X6T4   A0A2J7PU96   A0A2S2P698   A0A2H8TF37   A0A2J7PVX3   J9LFC9   Q8I7P8   A0A2J7PDM0   A0A2J7Q6J2   A0A069DZL8   A0A2J7QB68   A0A224X6R6   A0A2S2N814   A0A2M4BD83   K7IN67   A0A0A9YJ00   A0A0A9YU04   Q8T9X4   A0A2S2NPG3   A0A069DX78   A0A2S2R9D4   A0A1B6EGD8   A0A224X6U5   A0A224XI99   A0A2J7RD70   A0A224XJI0   A0A224X6W2   A0A2H8TKI9   A0A2S2PHL7   A0A2S2N6Q7   A0A232ENU1   A0A224XHW8   A0A224X746   A0A2A4IUM2   Q95SX7   A0A2J7PQB5   A0A2S2NH02   Q9NBX4   A0A2A4K918   A0A1W7R682  

EC Number

2.7.7.49

Pubmed

10333566    26354079    10380107    28004739    18362917    19820115    + More
25474469    8387152    30086797    26334808    20075255    25401762    28648823    7753626    12537569    11405632   

EMBL

U07847    AAA17752.1    AB018558    BAA76304.1    AB055391    BAB21761.1    + More
KQ459265    KPJ02064.1    AF081103    AAC72921.1    GEZM01008457    JAV94772.1    KQ973342    KXZ75569.1    KQ971729    KYB24751.1    GALX01005299    JAB63167.1    GALX01005359    JAB63107.1    GBBI01004395    JAC14317.1    GBBI01004571    JAC14141.1    ABLF02042518    ABLF02057746    S59870    AAB26437.2    GGMS01006359    MBY75562.1    GGMR01018716    MBY31335.1    RPOV01000134    RPJ78669.1    GGMS01002992    MBY72195.1    GGFL01004957    MBW69135.1    GGFL01005012    MBW69190.1    NEVH01006736    PNF36716.1    ABLF02008153    ABLF02008462    ABLF02008464    GFTR01008262    JAW08164.1    GGMR01003407    MBY16026.1    ABLF02034467    GFTR01008279    JAW08147.1    GGFJ01001858    MBW50999.1    NEVH01011985    PNF31054.1    GGFJ01001857    MBW50998.1    GGFJ01001844    MBW50985.1    GGFJ01001842    MBW50983.1    NEVH01027074    PNF13841.1    GGFJ01001843    MBW50984.1    KK119692    KFM76444.1    NEVH01009134    PNF33528.1    GFTR01008271    JAW08155.1    ABLF02036316    ABLF02036319    ABLF02048663    ABLF02066977    GFTR01008261    JAW08165.1    NEVH01021205    PNF19912.1    GGMR01012305    MBY24924.1    GFXV01000908    MBW12713.1    NEVH01020940    PNF20481.1    ABLF02023911    AY180919    AAN87272.1    NEVH01026386    PNF14434.1    NEVH01017470    PNF24199.1    GBGD01000415    JAC88474.1    NEVH01016302    PNF25823.1    GFTR01008269    JAW08157.1    GGMR01000676    MBY13295.1    GGFJ01001822    MBW50963.1    GBHO01010547    GBHO01010546    JAG33057.1    JAG33058.1    GBHO01021814    GBHO01010549    JAG21790.1    JAG33055.1    AF456125    AAL57609.1    GGMR01006408    MBY19027.1    GBGD01000389    JAC88500.1    GGMS01017365    MBY86568.1    GEDC01000337    JAS36961.1    GFTR01008251    JAW08175.1    GFTR01008256    JAW08170.1    NEVH01005295    PNF38784.1    GFTR01008257    JAW08169.1    GFTR01008260    JAW08166.1    GFXV01002840    MBW14645.1    GGMR01016296    MBY28915.1    GGMR01000226    MBY12845.1    NNAY01003095    OXU19992.1    GFTR01008254    JAW08172.1    GFTR01008151    JAW08275.1    NWSH01007753    PCG62823.1    AY060438    AAL25477.1    NEVH01022639    PNF18527.1    GGMR01003864    MBY16483.1    AF237761    AAF81411.1    NWSH01000032    PCG80496.1    GEHC01000968    JAV46677.1   

Proteomes

UP000053268    UP000007266    UP000007819    UP000235965    UP000054359    UP000002358    + More
UP000215335    UP000218220   

PRIDE

Q93137    Q9XXW0    Q9BPQ0    Q8I7P8    Q8T9X4    Q95SX7    + More
Q9NBX4   

Pfam

PF00078   RVT_1        + More
PF14529   Exo_endo_phos_2
PF07530   PRE_C2HC
PF03372   Exo_endo_phos

Interpro

IPR036691   Endo/exonu/phosph_ase_sf        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR000477   RT_dom       
IPR006579   Pre_C2HC_dom       
IPR036875   Znf_CCHC_sf       
IPR001878   Znf_CCHC       

SUPFAM

SSF56219   SSF56219        + More
SSF57756   SSF57756       

Gene 3D

3.60.10.10    

ProteinModelPortal

Q93137   Q9XXW0   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
A0A139W8G9   A0A139WA11   V5GNJ2   V5GNF3   A0A023EYS8   A0A023EZE6   X1WLB2   Q07995   A0A2S2QEE0   A0A2S2PPK8   A0A3N5Z7I3   A0A2S2Q383   A0A2M4CV52   A0A2M4CV42   A0A2J7R7D0   X1WNI2   A0A224XB44   A0A2S2NGV8   X1WZH0   A0A224X6Q4   A0A2M4BD67   A0A2J7QR37   A0A2M4BDV6   A0A2M4BD66   A0A2M4BDA5   A0A2J7PBY3   A0A2M4BD62   A0A087UGF5   A0A2J7QY69   A0A224X6S1   J9LC21   A0A224X6T4   A0A2J7PU96   A0A2S2P698   A0A2H8TF37   A0A2J7PVX3   J9LFC9   Q8I7P8   A0A2J7PDM0   A0A2J7Q6J2   A0A069DZL8   A0A2J7QB68   A0A224X6R6   A0A2S2N814   A0A2M4BD83   K7IN67   A0A0A9YJ00   A0A0A9YU04   Q8T9X4   A0A2S2NPG3   A0A069DX78   A0A2S2R9D4   A0A1B6EGD8   A0A224X6U5   A0A224XI99   A0A2J7RD70   A0A224XJI0   A0A224X6W2   A0A2H8TKI9   A0A2S2PHL7   A0A2S2N6Q7   A0A232ENU1   A0A224XHW8   A0A224X746   A0A2A4IUM2   Q95SX7   A0A2J7PQB5   A0A2S2NH02   Q9NBX4   A0A2A4K918   A0A1W7R682  

PDB

6AR3     E-value=0.000874759,     Score=105

KEGG

105842646    no KO assigned | (RefSeq) skin secretory protein xP2-like

GO

GO:0003964   GO:0004519   GO:0006313   GO:0008270   GO:0003676  

Length:

1173

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.36612

Exp number, first 60 AAs:

0.00074

Total prob of N-in:

0.00014

outside

1  -  1173

 

 

Pi

121.713378

Theta

106.271895

Tajima's D

0

CLR

14.993954

CSRT

0.369331533423329

Interpretation

Uncertain