Gene

KWMTBOMO02530

Pre Gene Modal

BGIBMGA002693

Annotation

PREDICTED:_guanine_nucleotide_exchange_factor_DBS_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr5(-):4909289-4924181      View in EpiBrowser

Location in the cell

Nuclear   Reliability : 3.322

CDS

ATGTTAAAAACGGGCTATAAAATTGTTAAGGATTTAACTGAGCATCATAAACCTATGGAAACATCTGGCGGTTCGGAGAGTTCCGGCGGTGACGACTCGGATGTTCGACGGTCTCGTCGCGGACACGTTCTAGCTGAACTAATGCAGACCGAGAAAGTATACGTGCAAGAACTCGGATCTATACTCTCTGGGTATAAAGAAGAAATCGAGAAGCCAGAGAACCAGCATCTCCTGCCGCCGACGCTGGTCGGACAGGCGGATGTGTTGTTCGGTAATCTGCACGAACTCTTCACATTCCACCAGGATGTCTTCCTTAAGGACCTGGAGCGATGCATTTCCGCTACAGAACTCGTCGCTTTGTGTTTTGTTGAGAAGAGGGAGACCTTCTTCAGACTGTACAGCTACTACTGTCAGAACATCCCTAGATCGGAGAGGTTGCGGGAGACGTTAGTGGATACGCATCTGTTCCTCCAGGCGTGTCAGCTGCGGCTCGGACACAAGCTGCCGCTGGCTGCGTACCTCCTGAAGCCGGTGCAGAGGATCACTAAATACCAGCTGCTGCTAAAGGATTTACTCCGATACAGCGAGTGTGGATCAATGACGACCGGCCTCCAGCAGGCCTTGGACTGCATGCTCGTCGTATTGAAATGCGTGAATGACTCCATGCACCAGATAGCCATAACCGGAGTCCCTGTGGACTTGAGTCAACAGGGCGAACTCCTGATGCAGGGCTCGTTCCTCGTGGTATCGGAGAACAAGCGCGACCTCCGCCTCAGGATACGGCCCCGGCGACGTCATATCTTCCTCTACGAGAAGGCCATGCTGTTCTGCAAGCCCGCCACAAAGAACAGCCACAATAAAGCCACTTACCACTTCAAACACGATCTGCTGATGTCACAAATAGGTCTTACGGAATCCGTTAAGGGCGATCTCCGCAAGTTCGAGGTGTGGCGCCAGGGCAGGTGTGAGGTGCACACGATCACGGCGCCCACGGTCGAGGTGAAGCGCGCCTGGGTCGAGCGGATCAAACGGGTGCTGCTCGACCAGCTGAAGGAACTCAAGGGCGAGCGAGTTCGGCAGTACGGACTGCAGCATCACAGAACACTAATCCAGACGAGCTCGTGGGAGGTGTCGGGCGCGCAGCCCCGCCCCCAACCCCCCACCGCGCCCCGCACCGGCTCGTGCGACGCGCACGACGAGCCCTGCTGGTCCACGGACCCCTCCGACGACGACGACGACGACGTCGAACACGCACCGAGAACGTGGATATTTCGGTTCTATTCGCTGAACATTAACTATCGTGCGGTGGGATGTGGACTGGTGGCGCTGTCCGACTACACAGCCGTGGGACCGAGCGAAGTGTCGCTGCGAGAGGGACAACACGCTGAACTACTCAAAGTCGGCTGTGCCGGCTGGTGGTACGTGCGGCTTGCAGGCGGACAAGGCGAGGGCTGGGCTCCGGCTGCCTACCTCGACCAGCGCAAGACGTCGCGCTCCTCCAGCAGGTCGCACGACCGCCTTCACGAGCATTGA

Protein

MLKTGYKIVKDLTEHHKPMETSGGSESSGGDDSDVRRSRRGHVLAELMQTEKVYVQELGSILSGYKEEIEKPENQHLLPPTLVGQADVLFGNLHELFTFHQDVFLKDLERCISATELVALCFVEKRETFFRLYSYYCQNIPRSERLRETLVDTHLFLQACQLRLGHKLPLAAYLLKPVQRITKYQLLLKDLLRYSECGSMTTGLQQALDCMLVVLKCVNDSMHQIAITGVPVDLSQQGELLMQGSFLVVSENKRDLRLRIRPRRRHIFLYEKAMLFCKPATKNSHNKATYHFKHDLLMSQIGLTESVKGDLRKFEVWRQGRCEVHTITAPTVEVKRAWVERIKRVLLDQLKELKGERVRQYGLQHHRTLIQTSSWEVSGAQPRPQPPTAPRTGSCDAHDEPCWSTDPSDDDDDDVEHAPRTWIFRFYSLNINYRAVGCGLVALSDYTAVGPSEVSLREGQHAELLKVGCAGWWYVRLAGGQGEGWAPAAYLDQRKTSRSSSRSHDRLHEH

Uniprot

A0A2A4J0E3   A0A2A4J0I0   A0A194QWQ3   A0A2H1WLV8   A0A212EGQ4   A0A194PEM5   + More
H9IZK8   A0A2A4J037   A0A0L0C320   A0A1L8DLV9   U5ESZ7   A0A0Q9WFQ6   A0A0Q9W443   A0A0Q9W4H1   A0A0R3NKM6   A0A0Q9W472   A0A0R3NKH8   A0A0R3NKJ1   A0A0R3NKH5   D6W697   A0A2M4CKW2   A0A2M4AJN2   A0A2M3Z8T7   A0A2M3Z8T4   A0A1B0B5C8   A0A084VF41   A0A2M4BB97   A0A0Q9XHX7   A0A0Q9XM44   A0A2M4BB98   A0A0Q9XKF3   A0A3B0J773   Q16L87   A0A2M4AGM3   A0A2M4CK05   A0A0Q9WNQ5   A0A1I8PJP2   A0A1Y1MPV4   A0A182XZA3   A0A1Y1MJQ8   A0A182FIB5   A0A1W4W002   A0A182T4R6   A0A182M338   B4GBJ1   W5JCB5   B3MBR4   E9J059   A0A0L7QS96   A0A154PP09   E2C515   A0A2A3E7G9   A0A310SAF2   A0A026WQL9   A0A3L8DL03   F4WV77   A0A195EW97   A0A195BTJ2   A0A2J7Q864   A0A158NNX2   A0A087ZVG3   A0A151WK14   A0A151IBC3   A0A0C9Q0X1   A0A182RB06   A0A182Q4T4   B4J9F0   E2AEK5   K7IR14   N6T989   A0A0K8UGA7   U4TZ26   A0A034V7T3   A0A034V3F9   A0A182WJ04   E0VRY6   A0A067QH20   A0A182NHA7  

Pubmed

26354079    22118469    19121390    26108605    17994087    15632085    + More
18057021    18362917    19820115    24438588    17510324    28004739    25244985    20920257    23761445    21282665    20798317    24508170    30249741    21719571    21347285    20075255    23537049    25348373    20566863    24845553   

EMBL

NWSH01004591    PCG64882.1    PCG64883.1    KQ461103    KPJ09390.1    ODYU01009553    + More
SOQ54061.1    AGBW02015043    OWR40669.1    KQ459606    KPI91811.1    BABH01014380    BABH01014381    BABH01014382    PCG64884.1    JRES01000960    KNC26720.1    GFDF01006754    JAV07330.1    GANO01002163    JAB57708.1    CH940648    KRF79867.1    KRF79865.1    KRF79864.1    CM000071    KRT01435.1    KRF79863.1    KRF79866.1    KRT01433.1    KRT01431.1    KRT01434.1    KQ971306    EFA11099.2    GGFL01001798    MBW65976.1    GGFK01007631    MBW40952.1    GGFM01004195    MBW24946.1    GGFM01004196    MBW24947.1    JXJN01008672    ATLV01012360    KE524785    KFB36585.1    GGFJ01001183    MBW50324.1    CH933808    KRG04868.1    KRG04867.1    GGFJ01001184    MBW50325.1    KRG04865.1    OUUW01000001    SPP75963.1    CH477917    EAT35078.1    GGFK01006605    MBW39926.1    GGFL01001479    MBW65657.1    CH963719    KRF97494.1    GEZM01029716    GEZM01029714    JAV85976.1    GEZM01029711    JAV85979.1    AXCM01015712    CH479181    EDW31286.1    ADMH02001929    ETN60469.1    CH902619    EDV38210.2    GL767291    EFZ13845.1    KQ414766    KOC61409.1    KQ435007    KZC13626.1    GL452714    EFN76969.1    KZ288345    PBC27655.1    KQ762207    OAD56051.1    KK107128    EZA58342.1    QOIP01000006    RLU21097.1    GL888384    EGI61843.1    KQ981953    KYN32421.1    KQ976417    KYM89751.1    NEVH01016978    PNF24765.1    ADTU01021865    ADTU01021866    KQ983031    KYQ48147.1    KQ978111    KYM96952.1    GBYB01007558    JAG77325.1    AXCN02000894    CH916367    EDW01431.1    GL438870    EFN68128.1    APGK01047262    KB741077    ENN74293.1    GDHF01026678    JAI25636.1    KB631673    ERL85283.1    GAKP01021137    JAC37815.1    GAKP01021136    JAC37816.1    DS235634    EEB16142.1    KK853797    KDQ71697.1   

Proteomes

UP000218220    UP000053240    UP000007151    UP000053268    UP000005204    UP000037069    + More
UP000008792    UP000001819    UP000007266    UP000092460    UP000030765    UP000009192    UP000268350    UP000008820    UP000007798    UP000095300    UP000076408    UP000069272    UP000192221    UP000075901    UP000075883    UP000008744    UP000000673    UP000007801    UP000053825    UP000076502    UP000008237    UP000242457    UP000053097    UP000279307    UP000007755    UP000078541    UP000078540    UP000235965    UP000005205    UP000005203    UP000075809    UP000078542    UP000075900    UP000075886    UP000001070    UP000000311    UP000002358    UP000019118    UP000030742    UP000075920    UP000009046    UP000027135    UP000075884   

PRIDE

H9IZK8   

Pfam

PF00621   RhoGEF        + More
PF00018   SH3_1
PF00169   PH
PF13716   CRAL_TRIO_2

Interpro

IPR001331   GDS_CDC24_CS        + More
IPR011993   PH-like_dom_sf       
IPR000219   DH-domain       
IPR001849   PH_domain       
IPR036028   SH3-like_dom_sf       
IPR001452   SH3_domain       
IPR035899   DBL_dom_sf       
IPR001251   CRAL-TRIO_dom       
IPR036865   CRAL-TRIO_dom_sf       
IPR018159   Spectrin/alpha-actinin       
IPR012337   RNaseH-like_sf       
IPR001584   Integrase_cat-core       

SUPFAM

SSF50044   SSF50044        + More
SSF48065   SSF48065       
SSF52087   SSF52087       
SSF53098   SSF53098       

Gene 3D

1.20.900.10     2.30.29.30     3.40.525.10    

CDD

cd00160  RhoGEF
cd00170  SEC14

ProteinModelPortal

A0A2A4J0E3   A0A2A4J0I0   A0A194QWQ3   A0A2H1WLV8   A0A212EGQ4   A0A194PEM5   + More
H9IZK8   A0A2A4J037   A0A0L0C320   A0A1L8DLV9   U5ESZ7   A0A0Q9WFQ6   A0A0Q9W443   A0A0Q9W4H1   A0A0R3NKM6   A0A0Q9W472   A0A0R3NKH8   A0A0R3NKJ1   A0A0R3NKH5   D6W697   A0A2M4CKW2   A0A2M4AJN2   A0A2M3Z8T7   A0A2M3Z8T4   A0A1B0B5C8   A0A084VF41   A0A2M4BB97   A0A0Q9XHX7   A0A0Q9XM44   A0A2M4BB98   A0A0Q9XKF3   A0A3B0J773   Q16L87   A0A2M4AGM3   A0A2M4CK05   A0A0Q9WNQ5   A0A1I8PJP2   A0A1Y1MPV4   A0A182XZA3   A0A1Y1MJQ8   A0A182FIB5   A0A1W4W002   A0A182T4R6   A0A182M338   B4GBJ1   W5JCB5   B3MBR4   E9J059   A0A0L7QS96   A0A154PP09   E2C515   A0A2A3E7G9   A0A310SAF2   A0A026WQL9   A0A3L8DL03   F4WV77   A0A195EW97   A0A195BTJ2   A0A2J7Q864   A0A158NNX2   A0A087ZVG3   A0A151WK14   A0A151IBC3   A0A0C9Q0X1   A0A182RB06   A0A182Q4T4   B4J9F0   E2AEK5   K7IR14   N6T989   A0A0K8UGA7   U4TZ26   A0A034V7T3   A0A034V3F9   A0A182WJ04   E0VRY6   A0A067QH20   A0A182NHA7  

PDB

1KZ7     E-value=3.4025e-75,     Score=718

KEGG

101739892    K20685 guanine nucleotide exchange factor MCF2 | (RefSeq) guanine nucleotide exchange factor DBS

GO

GO:0005089   GO:0035023   GO:0035556   GO:0016021   GO:0015074   GO:0005085   GO:0016740   GO:0005515   GO:0016776   GO:0006172   GO:0006631   GO:0006635   GO:0006281   GO:0048384  

Length:

510

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01407

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00553

outside

1  -  510

 

 

Pi

272.527369

Theta

189.266705

Tajima's D

1.453977

CLR

0.398735

CSRT

0.777661116944153

Interpretation

Uncertain