Gene

KWMTBOMO02515

Pre Gene Modal

BGIBMGA002698

Annotation

alpha-esterase_3_precursor_[Bombyx_mori]

Location

Bomo_Chr5(-):4482874-4485721      View in EpiBrowser

Full name

Carboxylic ester hydrolase      

Location in the cell

Cytoplasmic   Reliability : 1.748

CDS

ATGCGGCTTAAAGTTATATTACCTCTGCTTTTCTTCGCCAGTATCTCTGGTGAGGACTTTGAGTTGCCCATAGTAAATATAGGACAAGGCGCTGTGCTCGGTTCTCATGCTCACGATGGGGAATATTTTACGTTTTACGGGATCCCTTATGCCGATTCTACGTCAGGACCTCATCGGTTTAAGGCACCATCATCACCTCCAAAATTTGAAGGTGCCTTTGTAGCGAACAGAAGAGATGTAAAATGTGTAAGACCACTTGGAGTGGGCTATGAAGGGACAGAGGATTGTCTAGTAGTTGACGTGTTAACGCCTAATCTGGATGCTGCAGCTCAACTACCAGTGATGGTCTGGGTGAAGGGAAAAGAGTTCGACAGTGAATATAATCAAGATTTTTCATTCCGTAATTTCGTCCAGAAAGATGTCGTTGTAGTTTCAATCAACTTCCGTGAATCTATACTAGGATTTTTATGTTTGGGCACTGAAGTGGCTCCGGGAAATGCTGGATTGAAAGATATCATAGCCGGATTGAAATGGGTAAAAGAAAATATTGCTCATTTTGGAGGAAACCCAGACGATGTTACTTTGTTTGGTCATGGTAGTGGTGCTGCTGCTGTTGATTTGGTTACTTTGTCACCCTTAGCTAATGGATTAGTACACAAAGCTATAGCACAAAGCGGTAATGCATTTGCTCCATGGGCTGTAACCCGTGACAACTTAAACTATGCCATTCAAGTAGCAGAGGCTCTTGGACATATCGTGACGAACATTCAGGAACTCTCCGAAATATTTACTAGAACCAGTGTAGCTGCACTTATGGCCGTAATTAATGAATTGGATCTTACAGATAACTCATTGGCGTTTGCTCCATGCTTAGAACGAGAAGCGTTGAGTGTAGAATCATTTATCACTAAATCGCCCTACCAAACAATTTTAGATGGAGAATTTTTACAAATACCTTTCATGACTGGGTTTGTAGAAAACGAAGGTACAATTCGTGCCACAGAAGCAATAGAACACGACTGGTTGCAAAGAATGGAAACTTCATTTCCAGACTTTCTCCAACCGGACTTACAATTTGAAAACGCAGAGGGAGAATCAGCAATTGCAGAGGAAATAAAAGATTTTTATTTCAAAAACGAACTTATAAGTATGTTCAATATTGAGGACTACCTATCGTATCATGGTGATACAATGATACTAGTGTCAACAATTAGAGAAGCTCGTATTCGTGCTGCAAGTTCAAGTTCACCAGTTTATTTATATCAGTTTTCGTACAGTGGATCTTTAGGAAAACCTTTCGTTGGACCTATTCAAGTCGACGCAGCTGCACATAGCGAAGAATTGGCCTATATGTTTTATGAAAAATCGGATGATAATATCCCTTTGCTCGATCTTACAATTGGAGATATTTTAGTCGAAAGATGGACAAACTTCGCCAAAACTGGGGCACCGGTAAGTGAGACTTCTCAGGTAGTGTGGAGACCTTTTACCACCGAAAACAACCATTATTTAAGAATCCTTGATGACAGCGAAGTCCGAGGTGATCAAGAAACTACACTGGAACTGGATTTACAAAACCCTTATCCAGAAACACTATTATTCTGGGAGGAAATTTACAATGAACATTTCTTGGATGCCAGAGGTAAATGGGAACTAAGTGAAAGGACTGAGGGAACCGAAGACGGTGATGAAAACGGAAGTGGAGAAGAACTTCCGGAAAATGGTGGAGAGGCCGACAACGGAAGTGGTGAAGAAGTAGACGAGGGAAATGAAGGCGAGCCTGAAGAAGACGAGGGAAATGAAGGCGAGCCTGAAGAAGACGAGGGAAATGAAGGAGAGCCTGAAGAAGATAATACACCCGGATCAGCATCAACGGCTATAGCTTATACGTTTCCCATACTAACCGTGTTCGCGCTCATAAACAAATTGCACTTATCTCAGATCATGTCTTAA

Protein

MRLKVILPLLFFASISGEDFELPIVNIGQGAVLGSHAHDGEYFTFYGIPYADSTSGPHRFKAPSSPPKFEGAFVANRRDVKCVRPLGVGYEGTEDCLVVDVLTPNLDAAAQLPVMVWVKGKEFDSEYNQDFSFRNFVQKDVVVVSINFRESILGFLCLGTEVAPGNAGLKDIIAGLKWVKENIAHFGGNPDDVTLFGHGSGAAAVDLVTLSPLANGLVHKAIAQSGNAFAPWAVTRDNLNYAIQVAEALGHIVTNIQELSEIFTRTSVAALMAVINELDLTDNSLAFAPCLEREALSVESFITKSPYQTILDGEFLQIPFMTGFVENEGTIRATEAIEHDWLQRMETSFPDFLQPDLQFENAEGESAIAEEIKDFYFKNELISMFNIEDYLSYHGDTMILVSTIREARIRAASSSSPVYLYQFSYSGSLGKPFVGPIQVDAAAHSEELAYMFYEKSDDNIPLLDLTIGDILVERWTNFAKTGAPVSETSQVVWRPFTTENNHYLRILDDSEVRGDQETTLELDLQNPYPETLLFWEEIYNEHFLDARGKWELSERTEGTEDGDENGSGEELPENGGEADNGSGEEVDEGNEGEPEEDEGNEGEPEEDEGNEGEPEEDNTPGSASTAIAYTFPILTVFALINKLHLSQIMS

Similarity

Belongs to the type-B carboxylesterase/lipase family.

Feature

chain  Carboxylic ester hydrolase

Uniprot

B3GEF7   A0A194QV43   A0A2A4JJU8   A0A194PFJ7   A0A2H1VUM3   A0A0L7KMN7   + More
A0A1L8D6M3   A0A1U9X1Y3   A0A194QEV9   A0A212FDJ0   A0A1U9X1V8   A0A194QX52   A0A2S0D925   A0A194QF85   H9IX58   A0A1L8D6K3   A0A194QW56   A0A0L7LDE4   A0A2H1WJS1   A0A0C5CGY5   A0A1U9X1W8   A0A194RI11   A0A194PHG4   A0A0C5BXH0   A0A0Y0C087   M9WMP0   A0A2H1VEU9   A0A0L7KPV6   A0A2W1C2P3   A0A2H1V568   A0A2H1V567   A0A1U9X1S9   D3GDL5   A0A0K8TV95   D3GDM5   A0A2A4J3V0   D5G3D3   A0A194PQT2   A0A2A4J7A4   A0A2A4J0U9   A0A0F7QEE5   A0A2H1WQD3   A0A2H1VDR7   A0A0K8TVV9   A0A2A4J7M2   A0A2A4J3L3   D5G3D4   D5G3G3   A0A140IEY4   A0A2U3T8J8   A0A0K8TV81   D9IV61   A0A076FR95   A0A2H1V6G1   D9IV62   A0A2A4JX20   A0A2A4J321   A0A2A4JYH8   A0A0L7LBT9   A0A291P0Y8   H9JDE9   A0A127KQ69   A0A0K8TUP8   A0A146JVQ5   A0A2A4J7L0   A0A1U9X1U8   G0T5Q2   Q86MC7   A0A2H1V334   G1C2I4   A0A2A4J4E2   A0A2U3T8K8   A0A2H1V569   A0A076FRL8   D5G3C6   A0A2W1B1E5   A0A1J0M1W7   A0A2H1WW00   D5KXB8   H9ZVH4   D5KXB9   A0A2H1V6U9   A0A2A4J451   A0A0C5C590   A0A0K8TVU4   A0A2H1V574   S4WFZ6   D5G3E6   A0A2U3T8K6   A0A2A4J489   D3GDN1   D5KXA4   D5KXC0   A0A2A4JGH7  

EC Number

3.1.1.-

Pubmed

19121390    26354079    26227816    22118469    26778204    24753123    + More
28756777    26017144    20005949    25803580    20875855    24817326    28986331    23799064   

EMBL

BABH01014414    EU688969    ACD80423.1    KQ461103    KPJ09403.1    NWSH01001213    + More
PCG72099.1    KQ459606    KPI91798.1    ODYU01004540    SOQ44535.1    JTDY01008799    KOB64390.1    GEYN01000038    JAV02091.1    KY021872    AQY62761.1    KQ459053    KPJ04073.1    AGBW02009050    OWR51794.1    KY021852    AQY62741.1    KQ461073    KPJ09540.1    KX015848    ARM65377.1    KPJ04074.1    BABH01018297    KC200272    AGG20207.1    GEYN01000047    JAV02082.1    KPJ09539.1    JTDY01001568    KOB73502.1    ODYU01009112    SOQ53299.1    KP001157    AJN91202.1    KY021866    AQY62755.1    KQ460205    KPJ17074.1    KQ459604    KPI92154.1    KP001153    AJN91198.1    KU215372    AMB19666.1    KC493657    AGJ94046.1    ODYU01001984    SOQ38932.1    JTDY01007584    KOB65096.1    KZ149903    PZC78413.1    ODYU01000738    SOQ35977.1    SOQ35981.1    KY021822    AQY62711.1    FJ652447    ACV60231.1    GCVX01000044    JAI18186.1    FJ652457    ACV60241.1    NWSH01003330    PCG66539.1    FJ997297    ADF43462.1    KQ459602    KPI93490.1    NWSH01002873    PCG67404.1    NWSH01003909    PCG65705.1    LC017771    BAR64785.1    ODYU01010289    SOQ55290.1    ODYU01001983    SOQ38931.1    GCVX01000030    JAI18200.1    PCG67403.1    NWSH01003365    PCG66459.1    FJ997298    ADF43463.1    FJ997327    ADF43492.1    KT345936    AMO44416.1    KX015849    ARM65378.1    GCVX01000037    JAI18193.1    HM191471    ADJ96631.1    KF960790    AII21992.1    SOQ35982.1    HM191472    MF687569    ADJ96632.1    ATJ44495.1    NWSH01000416    PCG76541.1    PCG66537.1    PCG76543.1    JTDY01001757    KOB72967.1    MF687620    ATJ44546.1    BABH01030066    KT345938    AMO44418.1    GCVX01000023    JAI18207.1    GEDO01000023    JAP88603.1    PCG67402.1    KY021846    AQY62735.1    GU119888    ADK62515.1    AY091503    AAM14415.1    ODYU01000447    SOQ35237.1    JF728803    AEJ38205.1    PCG66538.1    KX015863    ARM65392.1    SOQ35983.1    KF960786    AII21988.1    FJ997290    ADF43455.1    KZ150466    PZC70779.1    KU375436    APD13878.1    ODYU01011476    SOQ57231.1    GU647143    ADE05556.1    JQ684436    AFH40334.1    GU647144    ADE05557.1    SOQ35984.1    PCG66458.1    KP001155    AJN91200.1    GCVX01000045    JAI18185.1    SOQ35978.1    KC589104    AGO98722.1    FJ997310    ADF43475.1    KX015860    ARM65389.1    PCG66546.1    FJ652463    ACV60247.1    GU647129    GU647130    GU647131    ADD97144.1    ADD97145.1    GU647145    ADE05558.1    NWSH01001662    PCG70492.1   

Proteomes

UP000005204    UP000053240    UP000218220    UP000053268    UP000037510    UP000007151    + More

PRIDE

B3GEF7    H9IX58    H9JDE9   

Pfam

PF00135   COesterase

Interpro

IPR002018   CarbesteraseB        + More
IPR029058   AB_hydrolase       
IPR019826   Carboxylesterase_B_AS       
IPR019819   Carboxylesterase_B_CS       
IPR002168   Lipase_GDXG_HIS_AS       
IPR011049   Serralysin-like_metalloprot_C       

SUPFAM

SSF53474   SSF53474       

Gene 3D

3.40.50.1820     2.150.10.10    

ProteinModelPortal

B3GEF7   A0A194QV43   A0A2A4JJU8   A0A194PFJ7   A0A2H1VUM3   A0A0L7KMN7   + More
A0A1L8D6M3   A0A1U9X1Y3   A0A194QEV9   A0A212FDJ0   A0A1U9X1V8   A0A194QX52   A0A2S0D925   A0A194QF85   H9IX58   A0A1L8D6K3   A0A194QW56   A0A0L7LDE4   A0A2H1WJS1   A0A0C5CGY5   A0A1U9X1W8   A0A194RI11   A0A194PHG4   A0A0C5BXH0   A0A0Y0C087   M9WMP0   A0A2H1VEU9   A0A0L7KPV6   A0A2W1C2P3   A0A2H1V568   A0A2H1V567   A0A1U9X1S9   D3GDL5   A0A0K8TV95   D3GDM5   A0A2A4J3V0   D5G3D3   A0A194PQT2   A0A2A4J7A4   A0A2A4J0U9   A0A0F7QEE5   A0A2H1WQD3   A0A2H1VDR7   A0A0K8TVV9   A0A2A4J7M2   A0A2A4J3L3   D5G3D4   D5G3G3   A0A140IEY4   A0A2U3T8J8   A0A0K8TV81   D9IV61   A0A076FR95   A0A2H1V6G1   D9IV62   A0A2A4JX20   A0A2A4J321   A0A2A4JYH8   A0A0L7LBT9   A0A291P0Y8   H9JDE9   A0A127KQ69   A0A0K8TUP8   A0A146JVQ5   A0A2A4J7L0   A0A1U9X1U8   G0T5Q2   Q86MC7   A0A2H1V334   G1C2I4   A0A2A4J4E2   A0A2U3T8K8   A0A2H1V569   A0A076FRL8   D5G3C6   A0A2W1B1E5   A0A1J0M1W7   A0A2H1WW00   D5KXB8   H9ZVH4   D5KXB9   A0A2H1V6U9   A0A2A4J451   A0A0C5C590   A0A0K8TVU4   A0A2H1V574   S4WFZ6   D5G3E6   A0A2U3T8K6   A0A2A4J489   D3GDN1   D5KXA4   D5KXC0   A0A2A4JGH7  

PDB

5TYJ     E-value=8.31451e-44,     Score=448

KEGG

100169706    no KO assigned | (RefSeq) ae3, Bmae3, Care-14; alpha-esterase 3

GO

GO:0080030   GO:0016787   GO:0016021  

SignalP

Position:   1 - 17,         Likelihood:  0.997072

 

 

Length:

650

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

4.85293

Exp number, first 60 AAs:

0.03035

Total prob of N-in:

0.00162

outside

1  -  650

 

 

Pi

194.773843

Theta

181.885546

Tajima's D

0.237605

CLR

0.211122

CSRT

0.441477926103695

Interpretation

Uncertain