Gene

KWMTBOMO02466

Pre Gene Modal

BGIBMGA002723

Annotation

PREDICTED:_solute_carrier_organic_anion_transporter_family_member_2A1-like_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr5(-):2763792-2797700      View in EpiBrowser

Full name

Solute carrier organic anion transporter family member       + More
Solute carrier organic anion transporter family member 74D      

Alternative Name

Ecdysone Importer
Organic anion transporting polypeptide 74D

Location in the cell

PlasmaMembrane   Reliability : 4.847

CDS

ATGACGGCGAGTTTCGTCGCGTCAGCATCAGCAGCGAGCGGGGAGGCGGTATCCCCGGGCCCGGCGGCCGAGGACGCCGCCATGAAAGGCGTCGAAGCTACACCCGAAGAACAGGAGAGATTAGCGACCGGAAATAACAATGGCTCTCTCGTCGCGAAGCTGCCGCCGAGGTCACAGCAGGCGCATCCGCGCTCTGCTTTTTACTCGACTCGAGTTTTCATGCTGGTCTTCCTGTCGGGCTGGGTGCTCCAGGGAATGTTCCTCACGTATTTCGTGAGCGTGACGACTACCCTAGAGAAGCTATATAAAGTTGAATCGAAGACGACAGGAACTTTACTGGCCGCTACGGAGATCGGACAAATATGTACGGCGTTATTCTTGACGTACTTAGCGGGGCGCGGACACAGACCGCGCTGGATCGCCTGCATGATGATGGTGCTGGCCGTGGGTGTGATAGGGTGTGTCATGCCGCACTTACTGTACGGCACCGAGCTGCTGAATGTCCACATAGACGGTCAGATAGCCGGCGCGGCACCCCTATGCAACGTCTACAACAACTTCACGTTGTGCAACTCCGATCAAATTAAAGTGACGGAAACGCGCTCATCTATAACCGCCGTCGTGATACCGTGGCTCTTCATCTGTCTCTTGGTAGTTGGCGTGGGACAAACCGGCATCGCAACGCTCGGAATACCTTACGTCGATGACAACGTAGGCAGCAGACAGTCCCCTCTTTACATGGCTATCACGATTGGCATCAGGGTGATCGGACCGGCGCTGGGATTCATGCTCGGTGCGTTTTGCACGAGGGTCTACGTCAATCCTCTAGTCGATCCAGGATTCGATTCCAGCGACCCAAAATGGGTCGGCGCATGGTGGCTCGGAATGGTGTTCATCGCCGGTTTCATCGTGATGCTATCGTGTCTGATGTTCTTCTTTCCGCGTCAGATCAAACCCGAACCGATCCAATTGCAGATGAAGAAGACCAAAGAGAAGCGAGAGCCGTTTGTCAAAGATTTCTTCGCGGCCATCAAGAGGCAGATTACGAACGACATTCTGATGTGGAGGACAGCCAGCTCCGTGTTGCATCTGATGCCGATCAGTGGAGTTTACAGTTTCCTACCCAAATATTTGGAGAAGCAGTTCCGACTCCCGACACACGATGCCAATCTTGTGTCTGCTCTCGGTGGTATCCTGGTGATGGGACTCGGTATAATAACGTCGGGAGTTGTCATATTGAAGCTTGTACCGTCCGCAAGACAGGTGGCCGCTTGGACTGCAGCCACAGCCGCCATTTATAGTGCCGGCATGGTGGCGCTGATGTTCGTGAGTTGCCCAGAGAAGAGTTACCGGTACCTGAGCGCGGCTTCCGACAGCGCCCTGCCCTGCAGCATGGCGTGTCACTGCGAGAACGCCTCCTTCAGCCCCGTCTGTGGACAGGATTCTTACACGTATCTCTCGCCCTGCCAGGCCGGCTGCATGGGAAGCATGCAGCTCGACAACAATACATTCTTGTATTATAATTGTTCGTGTATCAACGGAAGTGCGACAACCGATCTGGGGAAGCTGTACGATCTGCACAATAGAACGTTCCAGGAGCTGGCCGCGCCCGAGGGGTACGCGGTGAGCGGGGAGTGCGGGGTGCCGTGCTCGCAGATCTACGTCTTCATCGCCATCTTCGCGGCCATCATGTTCGTGCACGCCAGTGGAGAGGTCGGCGCCGTGCTGCTCATCATCCGCTGTACCGACAAGCACGACAAGGCGATGGCGATGGGCGTGATCCAGTTCGCCATCGGCGTGTTCGGCAACGTGCCGTGCCCCATCGTGTTCGGCGCGGCCGTGGACGCCGCGTGCCGCCTGCGGGACTACGCGTGCGGCGAGCTCGGCGCCTGCGTCTTCTACGACACGCACTCCTTCAGATACTTCTACTTGGGCCTCTCGGCAGCGATCATGTTCCTCGCCTTCATAATGGACCTGCTGGTGTGGAGTAAGGCGGGGCGCATCGACATGAACCCCAGCGAGGCGGGCGGCCCCCCCCTCCCCGCACTGGCGGCCTCACCCCCCGCGCCGCCCTCGCCGGACCACGTGCTGCTCGCAGCGCCCACCGACACGCAGCTGTGA

Protein

MTASFVASASAASGEAVSPGPAAEDAAMKGVEATPEEQERLATGNNNGSLVAKLPPRSQQAHPRSAFYSTRVFMLVFLSGWVLQGMFLTYFVSVTTTLEKLYKVESKTTGTLLAATEIGQICTALFLTYLAGRGHRPRWIACMMMVLAVGVIGCVMPHLLYGTELLNVHIDGQIAGAAPLCNVYNNFTLCNSDQIKVTETRSSITAVVIPWLFICLLVVGVGQTGIATLGIPYVDDNVGSRQSPLYMAITIGIRVIGPALGFMLGAFCTRVYVNPLVDPGFDSSDPKWVGAWWLGMVFIAGFIVMLSCLMFFFPRQIKPEPIQLQMKKTKEKREPFVKDFFAAIKRQITNDILMWRTASSVLHLMPISGVYSFLPKYLEKQFRLPTHDANLVSALGGILVMGLGIITSGVVILKLVPSARQVAAWTAATAAIYSAGMVALMFVSCPEKSYRYLSAASDSALPCSMACHCENASFSPVCGQDSYTYLSPCQAGCMGSMQLDNNTFLYYNCSCINGSATTDLGKLYDLHNRTFQELAAPEGYAVSGECGVPCSQIYVFIAIFAAIMFVHASGEVGAVLLIIRCTDKHDKAMAMGVIQFAIGVFGNVPCPIVFGAAVDAACRLRDYACGELGACVFYDTHSFRYFYLGLSAAIMFLAFIMDLLVWSKAGRIDMNPSEAGGPPLPALAASPPAPPSPDHVLLAAPTDTQL

Description

Transporter that mediates the cellular uptake of ecdysteroids, including ecdysone, from the hemolymph.

Similarity

Belongs to the organo anion transporter (TC 2.A.60) family.

Keywords

Cell membrane   Complete proteome   Disulfide bond   Glycoprotein   Ion transport   Membrane   Reference proteome   Transmembrane   Transmembrane helix   Transport  

Feature

chain  Solute carrier organic anion transporter family member 74D

Uniprot

A0A2A4J4A2   A0A2A4J5J2   A0A212ERD7   A0A2H1WD66   A0A2W1BSJ8   A0A1E1W444   + More
A0A0L7LRZ8   A0A1B0CGT2   A0A1L8DEP2   A0A1L8DF25   U5ET18   B4IX22   A0A1I8PJB5   A0A034V4S4   A0A0K8UQT9   B4PJU3   A0A1I8M4P6   B4HKT6   Q9VVH9   A0A0A1X228   A0A0A1X6A3   B4QNW1   B3NHU3   A0A1W4W4U7   A0A336MTR0   B4LFS2   A0A336MR54   A0A0C9RC20   A0A3B0KNA0   Q2LZI6   A0A0M3QVW4   B4KXF0   B4N6F0   A0A1A9UJ78   A0A0L0C7E8   A0A087ZVI3   A0A2A3EQZ7   A0A0P8XV32   A0A0L7QS98   B3M4J4   A0A1W4WNW5   A0A3B0JZ24   B4H6N4   K7J8P8   A0A0N0U548   A0A1B0D2N3   E2C8X8   A0A151J8N2   A0A224XFT4   A0A069DZE5   A0A158NUE8   A0A3L8DML1   A0A0A9ZGZ8   E2A200   A0A1B6JRS7   A0A232F6C2   A0A1B6E5P8   A0A023F3I6   F4X7Y0   A0A1A9XJH6   A0A1B0AY59   A0A195BSE0   A0A026WEC8   A0A154PPK8   A0A151INZ2   U4TZA6   A0A195FZC0   A0A067QTU5   A0A151WFY8   A0A1Y1N8A1   T1HYS5   A0A1J1IFS3   A0A2H8THD5   J9JWU7   A0A1L8DDU4   A0A1L8DDV7   E9GGR7   B7QN84   A0A1E1XJD1   A0A1E1X6Y5   A0A0N8A0I9   A0A0P5YEK7   A0A164ZDP8   A0A139WPJ4   A0A0P5SDN0   A0A0P4Y6G8   A0A0P6IX38   A0A0P4Y4C6   A0A0N8C7X8   A0A0P5MI44   A0A131YBZ6   A0A1D2NHJ0   L7M9R0   A0A0P6IKA7  

Pubmed

22118469    28756777    26227816    17994087    25348373    17550304    + More
25315136    10731132    12537572    12537569    30293839    25830018    22936249    18057021    15632085    23185243    26108605    20075255    20798317    26334808    21347285    30249741    25401762    26823975    28648823    25474469    21719571    24508170    23537049    24845553    28004739    21292972    29209593    28503490    18362917    19820115    26830274    27289101    25576852   

EMBL

NWSH01003244    PCG66699.1    PCG66700.1    AGBW02013039    OWR44058.1    ODYU01007860    + More
SOQ51001.1    KZ149951    PZC76605.1    GDQN01009314    GDQN01000931    JAT81740.1    JAT90123.1    JTDY01000216    KOB78245.1    AJWK01011571    GFDF01009151    JAV04933.1    GFDF01009150    JAV04934.1    GANO01002968    JAB56903.1    CH916366    EDV96328.1    GAKP01022217    JAC36735.1    GDHF01029417    GDHF01023368    JAI22897.1    JAI28946.1    CM000159    EDW94712.1    CH480815    EDW41891.1    AE014296    BT001436    AAN71191.1    GBXI01009115    JAD05177.1    GBXI01007881    JAD06411.1    CM000363    CM002912    EDX10863.1    KMZ00243.1    CH954178    EDV51958.1    UFQS01001935    UFQT01001935    SSX12731.1    SSX32173.1    CH940647    EDW69299.1    KRF84311.1    UFQT01002204    SSX32922.1    GBYB01004475    GBYB01004476    JAG74242.1    JAG74243.1    OUUW01000012    SPP87326.1    CH379069    EAL29521.2    CP012525    ALC43099.1    CH933809    EDW18636.1    CH964154    EDW79939.2    JRES01000810    KNC28200.1    KZ288193    PBC34158.1    CH902618    KPU78586.1    KQ414768    KOC61356.1    EDV40488.1    KPU78587.1    SPP87327.1    CH479214    EDW33462.1    KQ435792    KOX74274.1    AJVK01010705    AJVK01010706    AJVK01010707    GL453744    EFN75596.1    KQ979507    KYN21179.1    GFTR01007758    JAW08668.1    GBGD01000780    JAC88109.1    ADTU01026396    ADTU01026397    QOIP01000006    RLU21611.1    GBHO01000700    GBHO01000686    GBHO01000685    GDHC01010390    JAG42904.1    JAG42918.1    JAG42919.1    JAQ08239.1    GL435878    EFN72542.1    GECU01005821    JAT01886.1    NNAY01000897    OXU26023.1    GEDC01004089    JAS33209.1    GBBI01002846    JAC15866.1    GL888900    EGI57466.1    JXJN01005547    KQ976417    KYM89935.1    KK107256    EZA54288.1    KQ435007    KZC13677.1    KQ976899    KYN07171.1    KB631792    ERL86177.1    KQ981193    KYN45149.1    KK852945    KDR13456.1    KQ983203    KYQ46749.1    GEZM01010227    GEZM01010226    JAV94132.1    ACPB03009790    CVRI01000048    CRK99072.1    GFXV01000873    MBW12678.1    ABLF02033250    ABLF02033251    GFDF01009453    JAV04631.1    GFDF01009452    JAV04632.1    GL732543    EFX81434.1    ABJB011035923    DS976794    EEC20306.1    GFAA01004069    JAT99365.1    GFAC01004175    JAT95013.1    GDIP01194425    JAJ28977.1    GDIP01058790    JAM44925.1    LRGB01000725    KZS16237.1    KQ971306    KYB29909.1    GDIP01141433    JAL62281.1    GDIP01232880    JAI90521.1    GDIQ01016301    JAN78436.1    GDIP01232879    JAI90522.1    GDIQ01106035    JAL45691.1    GDIQ01157812    JAK93913.1    GEDV01012542    JAP76015.1    LJIJ01000036    ODN04733.1    GACK01005185    JAA59849.1    GDIQ01009667    JAN85070.1   

Proteomes

UP000218220    UP000007151    UP000037510    UP000092461    UP000001070    UP000095300    + More
UP000002282    UP000095301    UP000001292    UP000000803    UP000000304    UP000008711    UP000192221    UP000008792    UP000268350    UP000001819    UP000092553    UP000009192    UP000007798    UP000078200    UP000037069    UP000005203    UP000242457    UP000007801    UP000053825    UP000192223    UP000008744    UP000002358    UP000053105    UP000092462    UP000008237    UP000078492    UP000005205    UP000279307    UP000000311    UP000215335    UP000007755    UP000092443    UP000092460    UP000078540    UP000053097    UP000076502    UP000078542    UP000030742    UP000078541    UP000027135    UP000075809    UP000015103    UP000183832    UP000007819    UP000000305    UP000001555    UP000076858    UP000007266    UP000094527   

PRIDE

Q9VVH9   

Pfam

PF07648   Kazal_2        + More
PF03137   OATP

Interpro

IPR020846   MFS_dom        + More
IPR036259   MFS_trans_sf       
IPR004156   OATP       
IPR002350   Kazal_dom       
IPR036058   Kazal_dom_sf       

SUPFAM

SSF100895   SSF100895        + More
SSF103473   SSF103473       

CDD

cd06174  MFS

ProteinModelPortal

A0A2A4J4A2   A0A2A4J5J2   A0A212ERD7   A0A2H1WD66   A0A2W1BSJ8   A0A1E1W444   + More
A0A0L7LRZ8   A0A1B0CGT2   A0A1L8DEP2   A0A1L8DF25   U5ET18   B4IX22   A0A1I8PJB5   A0A034V4S4   A0A0K8UQT9   B4PJU3   A0A1I8M4P6   B4HKT6   Q9VVH9   A0A0A1X228   A0A0A1X6A3   B4QNW1   B3NHU3   A0A1W4W4U7   A0A336MTR0   B4LFS2   A0A336MR54   A0A0C9RC20   A0A3B0KNA0   Q2LZI6   A0A0M3QVW4   B4KXF0   B4N6F0   A0A1A9UJ78   A0A0L0C7E8   A0A087ZVI3   A0A2A3EQZ7   A0A0P8XV32   A0A0L7QS98   B3M4J4   A0A1W4WNW5   A0A3B0JZ24   B4H6N4   K7J8P8   A0A0N0U548   A0A1B0D2N3   E2C8X8   A0A151J8N2   A0A224XFT4   A0A069DZE5   A0A158NUE8   A0A3L8DML1   A0A0A9ZGZ8   E2A200   A0A1B6JRS7   A0A232F6C2   A0A1B6E5P8   A0A023F3I6   F4X7Y0   A0A1A9XJH6   A0A1B0AY59   A0A195BSE0   A0A026WEC8   A0A154PPK8   A0A151INZ2   U4TZA6   A0A195FZC0   A0A067QTU5   A0A151WFY8   A0A1Y1N8A1   T1HYS5   A0A1J1IFS3   A0A2H8THD5   J9JWU7   A0A1L8DDU4   A0A1L8DDV7   E9GGR7   B7QN84   A0A1E1XJD1   A0A1E1X6Y5   A0A0N8A0I9   A0A0P5YEK7   A0A164ZDP8   A0A139WPJ4   A0A0P5SDN0   A0A0P4Y6G8   A0A0P6IX38   A0A0P4Y4C6   A0A0N8C7X8   A0A0P5MI44   A0A131YBZ6   A0A1D2NHJ0   L7M9R0   A0A0P6IKA7  

KEGG

101741547    no KO assigned | (RefSeq) solute carrier organic anion transporter family member 3A1-like

GO

GO:0055085   GO:0016021   GO:0005215   GO:0006811   GO:0005886   GO:0043229   GO:0035076   GO:0002164   GO:0005887   GO:0071702   GO:0022804   GO:0022857   GO:0015347   GO:0043252   GO:0006810   GO:0016020   GO:0005515   GO:0031122   GO:0003924   GO:0005525   GO:0004518   GO:0006281   GO:0048384  

PANTHER

PTHR11388  

Subcellular location

Cell membrane  

Length:

706

Number of predicted TMHs:

12

Exp number of AAs in TMHs:

270.12168

Exp number, first 60 AAs:

0.00201

Total prob of N-in:

0.96958

inside

1  -  72

TMhelix

73  -  95

outside

96  -  109

TMhelix

110  -  132

inside

133  -  138

TMhelix

139  -  161

outside

162  -  208

TMhelix

209  -  231

inside

232  -  250

TMhelix

251  -  273

outside

274  -  287

TMhelix

288  -  310

inside

311  -  351

TMhelix

352  -  374

outside

375  -  393

TMhelix

394  -  416

inside

417  -  422

TMhelix

423  -  445

outside

446  -  556

TMhelix

557  -  579

inside

580  -  591

TMhelix

592  -  614

outside

615  -  640

TMhelix

641  -  663

inside

664  -  706

 

 

Pi

195.88484

Theta

170.99444

Tajima's D

-1.130275

CLR

1.203071

CSRT

0.112044397780111

Interpretation

Uncertain