Silkworm Genome Informatics Database

Gene

KWMTBOMO02428 Validated by peptides from experiments

Pre Gene Modal

BGIBMGA013512

Annotation

PREDICTED:_neuroblastoma-amplified_sequence-like_[Bombyx_mori]

Location

Bomo_Chr5(-):1788129-1817967 View in EpiBrowser

Full name

Neuroblastoma-amplified sequence

Alternative Name

Neuroblastoma-amplified gene protein

Location in the cell

Cytoplasmic Reliability : 1.575 Nuclear Reliability : 1.275

CDS

ATGTCGGAAGAGAATAAATCAATTCTCCACGAACTATACGTATATTCGGAATGGAAACCTGAACCAGAATATATTCAAAAACCTGATAACTTACTACTACCAGAAAACATATCATCTTTATGGAAGTGGCTTAAATTTTTTGGACCCAAGAAGAATTTAATAGACAGTGTAACTGCTCATAAAGAAAACCACCAAAAGTGGCATATCGCTCTCGGAGATGAAGGGAAAGTCATTGCTGTGTTAACTGACAATATATTGGAGATTAGAACAAAGAGATCTGACTATGCTACTATTGCTGCTAGAACTACAGTTAATAGGGATCCTTATTCACAATGGAGGAAACTCGTCTGGAGTCCTGATTGCTCCTTTGTGGTTCTAGCATATGGGAATGGCGTAGTTGGCTTCTTTGACTTGACTGCTTCAAACCTTTTCAATATTCCTATTGAATGTTCAAGACCAGAGGGCTTGGAGTGTTCAGACAACACTCATGCAGTCGCCGACGTTATATTCATGCCACTTAGGGTCAAAGACACAAAATGGAACTGGGAAGTTCTAATAGTGACATATGACGGTAAACTGCGTGGATATTTGGTATCGCAGACAGAAGGGTTCAAAATTCATCATACATTTAAATTCAGTGGAGGTGTGTCCGCTGTAGCATATAGTGATCGACATTCCACTCTTTACGTTGCTGGAGTACCTAGAGGTTCAGGAAAGGATCCGTCATCGCCTCTAAGCGCAGGACTCACAGCCTGGCGGATACTAAATGACGATCCATTCTATAAACTGTCTGTTGTGTCGGACGAGCTCGAGGCGCAGTTGGCAAATCAAAGATTCCAGCTTTACATTCCATTTGTAACTTCTAAGAATTTAGCATTCATAGTCCAAATGCAGCTGTCGCCCGACGCGACTAGACTCGTATGTCTGCACTGCAACGGAGACGTCTCGGTGTGGCGCCTCCCGCTGCTGAAAGCGGAACATCGGTGGCCCTTGGACACTCAACCGCTGCACGACCTAAGGAATCCGCTGAGCAATGATGATAAACCAACCAAGAAGGACCCGATCAAATATTACGTGGCTGATGTTAACTGGTGGAGTGGCGAGGAAATAATAGTGTCCAGATTCAGCGGCGCCGTGTCTGTGTGTCCCATCCAGGACATGATGAACATTCTCGGGAAGAAACCCGAGTTCTTCCAGGGCGCACCACGGATCACGTGTGCTCACGAGGGAACATTCATGGTGCTGGAATGCGAGTCTAATGTGTTGCCAGCGAAGAAATCACGAAGTGACGAAAGTATGGAAGTAGTGTCGACGGATAACGACGAAGAGGATACGATGTTTGAATTAACCAAAGAGCTGTTGAAGTCTGTGCTGTTCGCGATCACCGATATCGAGACCTTCCAGCCCAAGCCGAAGCGGATAACGGTCGTCTCCCGGGTGTACCGGCTGCTCGGAGTCAAGAGCACCACGCCCGCCGAACTATTCTCCAGGAAGATTGAAAGCGGCAAGTACACGGAAGCCTTGGCTTTGGCTGAAGAGTTTGGGCTGGACAGCGACTTGGTGTATCAGCAGCAGTGGAGGAAGAACCCTGTCTCTACAGAGGCCATACAGAAGTACTTGAGCAAAGTGTCTAAGAAGATCTGGGCGGTGCATCAGTGCGTGGACCGACTCCCCGAGACGCTACCGGCCGCCAAAGAACTACTGCAATTCGGGATTCAACTTACCAATGAGAGAATACTTGATGAAATAAATACGAACTCTGAGAACAAGATAGAAGATCCTGACAACATAACCCTGGAGCATCTCAACGCGTACACGAGCGAGCTGCTGCGCTGCAGGCACGTCATGCTCTTCTACAGAGATCGACTGGCGTTATATGAGGCGATTCTACGCTGTGAGAAATCAACGTACGTGAAAGACGAGTACGACCGGCTCCGCAGCAACAGCATCGTGCACAGCGCCGCCGAGACCGCCAAGGAAGGCCGCGTCGAGGCGCTCACCTGTCTGTGGCCTCAAATCAAAACGGTCCCCATGCAGCTGGCCGTTCTCGAGAAACTACCAGAGACAATCAACCCCATAGACTATCAACATTTGTTACCCACCAAGCAGGTCGTGCAGTGGTTCGAGAAGAAGTCCCCAATTAAACTGCCGCCGTCACAGTATGACAACGACTGGTGCCGCAAAGGCATCTTCAGGTCGATATGGAGTTCCAACTGGTCGGAAGACTGCACTCCCGATGTCGAGACCGTCGCGGATGTCTTAATAGAAGACGAAGAGTTAGGGAAATGGTACGAAAAGAGAGCGAGGGAGATCGAAGAGAGAAGCGGCATGGTTTCTCATTCTCTTACTCTTGTGACTATTGCGATGGTCGGCGGCGGCGTTCAAGGCTTAGACAAAATTATGTTTCACCTCATGACCCTGGACACTCTGGTCTACGATATAAACATCGAAGGGGTAACGCTCAAGCAGCTCGAAGGTCTGCCGCCGCTGGAAATTTGCACGCTGCTCATGAAAACGTCGACGGCAGAAACGTTCGTGTCGGACTTGAAGCAGTACGTGATCCCGTACCTGAAGCGCCTGGAGAACAGGTCCAAGGTCAACGACGTCTGCATCAACGGCCTCATCGATTATCTGGTGCATATAAGCATTGAAGACTTGTCTCCTATACTCCTGGTGTTGCAGTCACCGACGGAGTTCGCGCTAGATGTCTGCACTCATTTGGATCTAGTCGAAAAATGTTTCTTCGCCTACACCGGCACCGACCTGGAGAAAGCGAACGCCCTGCTCGACACTATACCGACAGAGAGCGACGGCAGCATGTCGACGGCGGCGCTGCAGAGCGCGGCGGGGCGCGTGCGGCGCGCGTGCGGCGGCTGGGCGGCGCTGGCGGCGCGCGGCGTGCGCGTGTCGGGCGGCGCGCTGCGGGACCTGGCGCCGCACCGCGACCAGGCGCACGCGCTGCTGCTGCGCCTCGCCAGGGCCCTGCCCGCCGTTGAAGAAAAACCAACTGCGCAAGATTGGGAGAAACTATTGAAAGACATATTGAATTTACAATCATCTTTATTCACCTGCATCAGTAAGACAGAATGCTATGAAATCTACGCCACGTCGTTACTAACGTCGGGACACTCGCCCAGCGTCCGGCTGGCGGCCGACGTCATGAACTGCTCGAAGTCGGCGCGGGGGGACAGCCGGAAGGTGCCGTACCCTAAGGCCTTGGAGCTGGTGCTGGCCGCCGCCACTGAGTACGTCAACTCCGCATCAGGACTCGAGGATCCCGCTCTCGATATTGCCAGGACGTGTCTAATGCTGATAAAAGAAAAAAATGTAAAGAAAATCGAAGAAGAGCTGGATCTGATCTCGTCATTTCAAATACTCAATTCGTTTGAGGTCCCGCTACTGCCCATACAAGTACGTTTGTGCGAAGACAGACTGTCTCTGGTCGAGCAGTGCCTGAGGCTGGACCTGAACGGGTACCTGGCGGGCCCCAAGCTGCTGAAGCTGGCCACGCTGCTGAGGGTGGCCGGAGACGACGAGCACACTCGCGAGGGTGAAGTACTGTCGCTGATCGGCAAGTACGCGCTGGAGGCGGGCGCAGCAGGTGCGGGCGCGGCGGCGGAGGCGGGCGCGCGTCTGGCGGCGCTGCGCTACCCGCCCGCCGCGGCGCTGCTGGCCCGCCTGGCCGCGCTGGCCGCGCCCGCCCGCCCGCCGCACGCCCGCGACCTGTACGCCGCCGCGCTCACCTACTGCCACGCGAACCAGATGCACGACATGCTCACTGCTCGGTTGAGCTTGGAGTTGGAGAGTCTCCAGCAGACCGGCGTGTTCGTAAGGGAGCAGCAGTTCCTGACCGACCGATGGCCCTCCACAGACGACGAGTTCGCCGACGCCATAACAACTCCGGTGATCGAGAGGAAAGATATCGTGCCCACCGCTAAAGACAAGAAGCCACCAAGGAATTATGTCCTAAACACGTTTCAATATAAGTACGATATAAGTGAGAAGTCGAGTCCGGAGAGCGCGGAGGTGCGCTACCCGGAGTGGTACGCGCGTGTGTACGGGGGCGGGGCGCGCGCGGGGGGTGACGAGGTGCCTGCGGGGGGTGATGGGGCGCCCGCGGGGGGCGATGGGGGACACTACTCGTACGGCCGGTTCGCGATGGAGCGCCCGACCGGCACTGCGCATGCGCTGCTCTCCGCCTACTACATACAAAACTGTCTCGAACACGGATACACGGCGCAGCTAGAGGCCGAATTGGTCCAGAAGTGCGGGGAAGAGCTGCTGTACAGAGACACGCCGCTGAGCGTGGCCTGCCTGCTGCGGTCCACTCAGGAGTACGACGTGACGAAGAAGTTCTTGGAGAGTCAGCACACGGACGCGGCCGTCAGCTGCGCGCTGTACGCGACGCTCGTGCACTGCAACTCGGCCGCGCTGCGGGACGACGTGTACTTGACCAAGCCGACCAAAATGGCCAGGATGACTTTGAAGCAGAAGAACGCTTCGGAAGTGCAGCTGAAGGTGATCAACGAGTGCGTCGACAAGCTGACCGGCATGGGCGAGGTGGCCGCGCTGCGCAACCTCGGCGTCGCGGTCAACGGGCTCCTCTTCAACGTCGACGACGACTACAGGCGGGAGCTCATCTACAGGCTCGCCGGGTCTAAGGAGAAGAAGCACGTGGAGGTGGCGTGTTCTCTGGCGGACAAGTACGGGCTGGACGCGCTGGAGATGTGGCTCGCGCACGCGGGGACCGCGGGCCGCCTCGCCGCGCCCCCCCGCCTCGCCGCCCGCCTCACCGCTGACCTCGCCGCCTACAACCGAATACGAGAAGTGCTCTGGCCGCAGCTCCGCGGCGACGACCACAGCTCGCTCATTAACTTCTTCACGTTGCTGAAAGGGATCGATGAGAAACAAGTGCTCTTCGGAATGACCGTCATGGAGCACATCAAGCTGCTCAAGAAAGCCAAAGCTGCTTCCCCAGAGCTGGACTACAAGCTGCTGCTGGAGCCGGGCGCGGCGGAGCGTCTGTCTGCGCACCTGGTGGACATCATGAGGCCGGAGAACGTGGGCATCGTCGGCAAGTTCCTCAGGACACTGCCGCCCGCCTTCAAGACGCCCATTTCCATCAACAGCATCTACACGAAGTGGCTCACCAAACATTTTTTTAGCGTCCCTTCGAACGCGACCAACAAGAAGTGGATGCAACAATACAGACAATGCTCGAGCTACTTCAACAAGCTCTCCAAAGAGGATCTCCTGCAGTTTGTGGCCGACACTTGCTTCTCTGATGACGCGGTTCAACGCGTTCCTGCCGGTACTCGCAGCCTGATGATACTACAAGCGGTCGATTACTGCCAGCAAGAGCAGGAGAACGATCACAAGTCGAACAAGAGCGAACAAACATGGGCGCAAGTAGGACAGGAGCTGACGCGCTGGGCTCGCTTCCTGGAGAACTTCCACTCGTCCAGCGTGCAGGCCATCATCGACTCCACGGACGTGCCCCGGGATACGATTTGGCCGTGA

Protein

MSEENKSILHELYVYSEWKPEPEYIQKPDNLLLPENISSLWKWLKFFGPKKNLIDSVTAHKENHQKWHIALGDEGKVIAVLTDNILEIRTKRSDYATIAARTTVNRDPYSQWRKLVWSPDCSFVVLAYGNGVVGFFDLTASNLFNIPIECSRPEGLECSDNTHAVADVIFMPLRVKDTKWNWEVLIVTYDGKLRGYLVSQTEGFKIHHTFKFSGGVSAVAYSDRHSTLYVAGVPRGSGKDPSSPLSAGLTAWRILNDDPFYKLSVVSDELEAQLANQRFQLYIPFVTSKNLAFIVQMQLSPDATRLVCLHCNGDVSVWRLPLLKAEHRWPLDTQPLHDLRNPLSNDDKPTKKDPIKYYVADVNWWSGEEIIVSRFSGAVSVCPIQDMMNILGKKPEFFQGAPRITCAHEGTFMVLECESNVLPAKKSRSDESMEVVSTDNDEEDTMFELTKELLKSVLFAITDIETFQPKPKRITVVSRVYRLLGVKSTTPAELFSRKIESGKYTEALALAEEFGLDSDLVYQQQWRKNPVSTEAIQKYLSKVSKKIWAVHQCVDRLPETLPAAKELLQFGIQLTNERILDEINTNSENKIEDPDNITLEHLNAYTSELLRCRHVMLFYRDRLALYEAILRCEKSTYVKDEYDRLRSNSIVHSAAETAKEGRVEALTCLWPQIKTVPMQLAVLEKLPETINPIDYQHLLPTKQVVQWFEKKSPIKLPPSQYDNDWCRKGIFRSIWSSNWSEDCTPDVETVADVLIEDEELGKWYEKRAREIEERSGMVSHSLTLVTIAMVGGGVQGLDKIMFHLMTLDTLVYDINIEGVTLKQLEGLPPLEICTLLMKTSTAETFVSDLKQYVIPYLKRLENRSKVNDVCINGLIDYLVHISIEDLSPILLVLQSPTEFALDVCTHLDLVEKCFFAYTGTDLEKANALLDTIPTESDGSMSTAALQSAAGRVRRACGGWAALAARGVRVSGGALRDLAPHRDQAHALLLRLARALPAVEEKPTAQDWEKLLKDILNLQSSLFTCISKTECYEIYATSLLTSGHSPSVRLAADVMNCSKSARGDSRKVPYPKALELVLAAATEYVNSASGLEDPALDIARTCLMLIKEKNVKKIEEELDLISSFQILNSFEVPLLPIQVRLCEDRLSLVEQCLRLDLNGYLAGPKLLKLATLLRVAGDDEHTREGEVLSLIGKYALEAGAAGAGAAAEAGARLAALRYPPAAALLARLAALAAPARPPHARDLYAAALTYCHANQMHDMLTARLSLELESLQQTGVFVREQQFLTDRWPSTDDEFADAITTPVIERKDIVPTAKDKKPPRNYVLNTFQYKYDISEKSSPESAEVRYPEWYARVYGGGARAGGDEVPAGGDGAPAGGDGGHYSYGRFAMERPTGTAHALLSAYYIQNCLEHGYTAQLEAELVQKCGEELLYRDTPLSVACLLRSTQEYDVTKKFLESQHTDAAVSCALYATLVHCNSAALRDDVYLTKPTKMARMTLKQKNASEVQLKVINECVDKLTGMGEVAALRNLGVAVNGLLFNVDDDYRRELIYRLAGSKEKKHVEVACSLADKYGLDALEMWLAHAGTAGRLAAPPRLAARLTADLAAYNRIREVLWPQLRGDDHSSLINFFTLLKGIDEKQVLFGMTVMEHIKLLKKAKAASPELDYKLLLEPGAAERLSAHLVDIMRPENVGIVGKFLRTLPPAFKTPISINSIYTKWLTKHFFSVPSNATNKKWMQQYRQCSSYFNKLSKEDLLQFVADTCFSDDAVQRVPAGTRSLMILQAVDYCQQEQENDHKSNKSEQTWAQVGQELTRWARFLENFHSSSVQAIIDSTDVPRDTIWP

Description

Involved in Golgi-to-endoplasmic reticulum (ER) retrograde transport; the function is proposed to depend on its association in the NRZ complex which is believed to play a role in SNARE assembly at the ER (PubMed:19369418).

Subunit

Component of the NRZ complex composed of NBAS, ZW10 and RINT1/TIP20L; NRZ associates with SNAREs STX18, USE1L, BNIP1/SEC20L and SEC22B (the assembly has been described as syntaxin 18 complex); links NRZ to SNARE USE1L (PubMed:19369418).

Keywords

Acetylation Alternative splicing Complete proteome Cytoplasm Disease mutation Dwarfism Endoplasmic reticulum Membrane Phosphoprotein Polymorphism Protein transport Reference proteome Repeat Transport WD repeat

Feature

chain  Neuroblastoma-amplified sequence
splice variant  In isoform 2.
sequence variant  In dbSNP:rs77081203.

Uniprot

A0A2A4JMH6 A0A212FIR2 A0A3B3TSX7 A0A3B3YI59 A0A131XQ60 G1UI26 + More
A0A3Q0G330 A0A3B5Q5M2 A0A3B5QYW4 H3DFW0 A0A340YE85 A0A1U7R1H6 A0A3P9P615 A0A1U8C771 H2UU11 A0A1U8CA63 A0A1U8CI35 A0A1U8CI25 A0A1D5P365 A0A2Y9K6A5 M3ZQR0 A0A146WFC1 A0A2Y9KIP5 A0A096NJC6 G1NZ72 G7PLM6 A0A2I0MUM1 H9FVM8 F7F4R5 A0A1V4JN24 A0A147A246 A0A2Y9S895 A0A2K5NT63 A0A2K5Y8V1 A0A2J8V4B0 G3R1H8 A0A2R9AQE7 H2P6X5 A0A2K5WCW4 F1M0U5 G7NBB2 A2RRP1 A0A0D9R5C0 A0A3L8T074 U3IY93 U6DDN1 G1RW92 A0A2Y9S8U4 K9IPL1 A0A2Y9SC33 A0A2K6EC19 A0A2K6UAK3 A0A2K5QXK1 K7ASJ0 A0A2K5CEZ1 A0A2K6RHS1

Pubmed

22118469 21697133 23542700 15496914 21551351 15592404 + More
21993624 22002653 23371554 25319552 17431167 22398555 22722832 15057822 22673903 12706883 15815621 15489334 9926938 17974005 10882752 18669648 18318008 19413330 19369418 19690332 19608861 20577004 20462495 21269460 21406692 23186163 24275569 26073778 26286438 30282656 23749191 25362486

EMBL

NWSH01001095 PCG72633.1 AGBW02008342 OWR53625.1 GEFM01007009 JAP68787.1 + More
AB621813 BAK64149.1 AADN05000843 GCES01058424 JAR27899.1 AHZZ02004958 AAPE02031316 AAPE02031317 CM001288 EHH55371.1 AKCR02000002 PKK33375.1 JU334934 AFE78687.1 JSUE03010259 JSUE03010260 JSUE03010261 JSUE03010262 LSYS01006902 OPJ73581.1 GCES01013649 JAR72674.1 NDHI03003434 PNJ52331.1 CABD030014149 CABD030014150 CABD030014151 CABD030014152 CABD030014153 CABD030014154 CABD030014155 CABD030014156 CABD030014157 CABD030014158 AJFE02094744 AJFE02094745 AJFE02094746 ABGA01151179 ABGA01151180 ABGA01151181 ABGA01151182 ABGA01151183 ABGA01151184 ABGA01151185 ABGA01151186 ABGA01151187 ABGA01151188 AQIA01018998 AQIA01018999 AQIA01019000 AQIA01019001 AQIA01019002 AQIA01019003 AABR07063636 AABR07063637 AABR07063638 AABR07063639 CM001265 EHH21899.1 AF388385 AC007738 AC074184 AC008278 AC008282 BC051792 BC108693 BC131735 AF056195 AL050281 AQIB01031915 AQIB01031916 AQIB01031917 AQIB01031918 AQIB01031919 AQIB01031920 AQIB01031921 AQIB01031922 AQIB01031923 AQIB01031924 QUSF01000002 RLW12372.1 ADON01011224 ADON01011225 ADON01011226 ADON01011227 ADON01011228 ADON01011229 ADON01011230 ADON01011231 HAAF01008897 CCP80721.1 ADFV01073391 ADFV01073392 ADFV01073393 ADFV01073394 ADFV01073395 ADFV01073396 ADFV01073397 ADFV01073398 ADFV01073399 ADFV01073400 GABZ01003407 JAA50118.1 GABC01008618 JAA02720.1

Proteomes

UP000218220 UP000007151 UP000261500 UP000261480 UP000189705 UP000002852 + More
UP000007303 UP000265300 UP000189706 UP000242638 UP000005226 UP000000539 UP000248482 UP000028761 UP000001074 UP000009130 UP000053872 UP000006718 UP000190648 UP000233060 UP000233140 UP000001519 UP000240080 UP000001595 UP000233100 UP000002494 UP000005640 UP000029965 UP000276834 UP000016666 UP000001073 UP000248484 UP000233120 UP000233220 UP000233040 UP000233020 UP000233200

PRIDE

G1UI26 F1M0U5 A2RRP1

Pfam

PF08314 Sec39 + More
PF15492 Nbas_N

Interpro

IPR036322   WD40_repeat_dom_sf        + More
IPR013244   Sec39_domain
IPR029145   NBAS_N
IPR015943   WD40/YVTN_repeat-like_dom_sf
IPR001680   WD40_repeat
IPR011044   Quino_amine_DH_bsu
IPR016024   ARM-type_fold

SUPFAM

SSF50978   SSF50978        + More
SSF50969   SSF50969
SSF48371   SSF48371

Gene 3D

2.130.10.10

ProteinModelPortal

A0A2A4JMH6 A0A212FIR2 A0A3B3TSX7 A0A3B3YI59 A0A131XQ60 G1UI26 + More
A0A3Q0G330 A0A3B5Q5M2 A0A3B5QYW4 H3DFW0 A0A340YE85 A0A1U7R1H6 A0A3P9P615 A0A1U8C771 H2UU11 A0A1U8CA63 A0A1U8CI35 A0A1U8CI25 A0A1D5P365 A0A2Y9K6A5 M3ZQR0 A0A146WFC1 A0A2Y9KIP5 A0A096NJC6 G1NZ72 G7PLM6 A0A2I0MUM1 H9FVM8 F7F4R5 A0A1V4JN24 A0A147A246 A0A2Y9S895 A0A2K5NT63 A0A2K5Y8V1 A0A2J8V4B0 G3R1H8 A0A2R9AQE7 H2P6X5 A0A2K5WCW4 F1M0U5 G7NBB2 A2RRP1 A0A0D9R5C0 A0A3L8T074 U3IY93 U6DDN1 G1RW92 A0A2Y9S8U4 K9IPL1 A0A2Y9SC33 A0A2K6EC19 A0A2K6UAK3 A0A2K5QXK1 K7ASJ0 A0A2K5CEZ1 A0A2K6RHS1

KEGG

101744793 K20473 neuroblastoma-amplified sequence | (RefSeq) neuroblastoma-amplified sequence-like

GO

GO:0006890 GO:0000184 GO:0043009 GO:2000623 GO:0000149 GO:0070939 GO:0000956 GO:0015031 GO:0016020 GO:0005783 GO:0005829 GO:0005789 GO:0005515 GO:0006412 GO:0004175 GO:0005089 GO:0035023 GO:0006289 GO:0004518 GO:0006281 GO:0048384

Subcellular location

Cytoplasm
Endoplasmic reticulum
Endoplasmic reticulum membrane

Length:

1839

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.750259999999996

Exp number, first 60 AAs:

0

Total prob of N-in:

0.03474

outside

1 - 1839

Pi

333.575026

Theta

190.562764

Tajima's D

2.558868

CLR

0.396115

CSRT

0.950952452377381

Interpretation

Uncertain

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics