Gene

KWMTBOMO02422  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA013493

Annotation

phosphohistidine_phosphatase_[Bombyx_mori]

Location

Bomo_Chr5(+):1764938-1767703      View in EpiBrowser

Full name

Sex-regulated protein janus-A       + More
14 kDa phosphohistidine phosphatase      

Alternative Name

Phosphohistidine phosphatase 1
Protein histidine phosphatase

Location in the cell

Cytoplasmic   Reliability : 1.447 Mitochondrial   Reliability : 1.454

CDS

ATGCCTTTTAATCCTTTCAAATTATTTAGTCGACCCCGAGTAAATAATACCAAATTCTGGAACCCAAATTTATCAGGGCCAATATTACAATTTACCACAAAAATGTCTGGCTCACTCCACAAAGTTCCTAAAGTGGACATTGATAAATCTGGAGTATTCAAGTACATCCTCCTGAAGGTCTATGACCAAGAAGTTGATGGAGTGGAACCTTCCACTATTGTCTTAAGAGGATATAAGAGATGCAACTATCACTCTGATATATATGATGAGGTACAAGGTAAATTAATCCCCTTTGATTGTGAGCCTTGGGGTGGTGGTAGAATATCTCATGATCCAGACAATAAGAAGATACACATCTATGGATACTCTCAGGCCTATGGAAAGGCAGACCATGAGGAGGCAGCCAAACTAATCAAGAATGCATATCCAGATTACACAATCACAATCAGTGATGAAGGATACTAA

Protein

MPFNPFKLFSRPRVNNTKFWNPNLSGPILQFTTKMSGSLHKVPKVDIDKSGVFKYILLKVYDQEVDGVEPSTIVLRGYKRCNYHSDIYDEVQGKLIPFDCEPWGGGRISHDPDNKKIHIYGYSQAYGKADHEEAAKLIKNAYPDYTITISDEGY

Description

JanA and janB regulate somatic sex differentiation.
Exhibits phosphohistidine phosphatase activity.

Catalytic Activity

H2O + N(pros)-phospho-L-histidyl-[protein] = L-histidyl-[protein] + phosphate
H2O + N(tele)-phospho-L-histidyl-[protein] = L-histidyl-[protein] + phosphate

Subunit

Monomer.

Similarity

Belongs to the janus family.

Keywords

Complete proteome   Differentiation   Reference proteome   Sexual differentiation   Cytoplasm   Hydrolase   Protein phosphatase   Acetylation  

Feature

chain  Sex-regulated protein janus-A

Uniprot

Q2F5N5   H9JVD0   A0A1E1VX92   A0A2H1VDJ4   A0A2W1BK75   A0A2A4JLE7   + More
S4PGJ4   A0A0L7L2G8   A0A212F5L1   A0A194Q4N4   A0A0N1PGL2   A0A0N1PI35   A0A182R4T0   A0A1I8NB48   A0A1B6LYP8   A0A2M4CZN2   A0A0V0GDK6   A0A182VWL1   A0A182YHG7   A0A182T9L2   A0A1B6H1Q8   A0A2M4AY21   A0A069DP21   A0A2M3ZDK6   A0A182FNZ3   A0A2M4C3L3   A0A336MDK8   A0A182MKI6   A0A088ACD4   A0A2M4AY66   A0A182HZZ2   A0A3B3U8L0   A0A182Q8C2   A0A182P575   A0A182N5U6   A0A182ILD5   A0A0K8THC0   A0A0A9ZD48   A0A0L0CHZ4   I5AMV9   P54364   A0A0P4VLC5   R4FMN8   A0A023F860   A0A182V6Q2   A0A182TJU1   A0A182LR35   A0A182X0A2   Q7PUI9   A0A224XWS2   A0A2M4CTP6   A0A1B6HP61   A0A1S4F7C0   A0A182JVI0   A0A3B3WX09   A0A087X7T5   A0A087X5G2   B4NJJ3   B4GNH7   D0QWR6   U5EVH9   A0A0S7LEG5   A0A146R1V4   A0A3B0K7G7   A0A147A8G3   M3ZLH2   A0A2A3EHH3   A0A182G4V8   G3IHB0   F6WVK9   A0A0M4F3P7   Q17D02   A0A1Q3FBA0   B0WP95   A0A1A9WT60   A0A226NGC1   A0A226PMI4   A0A2P4S9G9   H0XUK7   Q9DAK9   A0A1A9VDH0   A0A1D5PWG8   D3ZP47   A0A3B4ANQ6   A0A250Y9L6   A0A3B4AME5   A0A0A9X5P1   A0A023EDZ0   I3NEJ4   A0A2K6EIY3   G3Q237   A0A3P9K6C4   A0A3B3H9F4   A0A3B3C695   R7U055   Q32PA4   A0A0M3KB29   A0A1U7R1F2   A0A3P9JMV2   A0A0K8TQA2  

EC Number

3.9.1.3

Pubmed

19121390    28756777    23622113    26227816    22118469    26354079    + More
25315136    25244985    26334808    25401762    26823975    26108605    15632085    17994087    7700229    27129103    25474469    20966253    12364791    19859648    23542700    26483478    21804562    29704459    17495919    17510324    24621616    16141072    15489334    21183079    15592404    15057822    15632090    22673903    25463417    28087693    24945155    17554307    29451363    23254933    26369729   

EMBL

DQ311388    ABD36332.1    BABH01036055    GDQN01011706    JAT79348.1    ODYU01001972    + More
SOQ38909.1    KZ150118    PZC73236.1    NWSH01001095    PCG72639.1    GAIX01006190    JAA86370.1    JTDY01003397    KOB69620.1    AGBW02010179    OWR49018.1    KQ459465    KPJ00309.1    KQ460393    KPJ15379.1    LADJ01008100    KPJ20915.1    GEBQ01018260    GEBQ01011159    JAT21717.1    JAT28818.1    GGFL01006614    MBW70792.1    GECL01000722    JAP05402.1    GECZ01001160    JAS68609.1    GGFK01012324    MBW45645.1    GBGD01003493    JAC85396.1    GGFM01005820    MBW26571.1    GGFJ01010752    MBW59893.1    UFQT01000991    SSX28326.1    AXCM01002444    GGFK01012207    MBW45528.1    APCN01002026    AXCN02001153    GBRD01001291    JAG64530.1    GBHO01031187    GBHO01031186    GBHO01031185    GBHO01031183    GBHO01003881    GBHO01003879    GDHC01015863    GDHC01005617    JAG12417.1    JAG12418.1    JAG12419.1    JAG12421.1    JAG39723.1    JAG39725.1    JAQ02766.1    JAQ13012.1    JRES01000378    KNC31832.1    CM000070    EIM52294.1    S77099    GDKW01003164    JAI53431.1    GAHY01000908    JAA76602.1    GBBI01001275    JAC17437.1    AAAB01008987    EAA01434.5    GFTR01002098    JAW14328.1    GGFL01004544    MBW68722.1    GECU01031236    JAS76470.1    AYCK01016959    AYCK01026587    CH964272    EDW83917.1    CH479186    EDW39303.1    FJ821034    ACN94747.1    GANO01003398    JAB56473.1    GBYX01173258    JAO87841.1    GCES01123887    JAQ62435.1    OUUW01000005    SPP80941.1    GCES01011505    JAR74818.1    KZ288256    PBC30636.1    JXUM01144562    KQ569817    KXJ68510.1    JH002744    RAZU01000235    EGW14296.1    RLQ63888.1    CP012526    ALC46262.1    CH477301    EAT44257.1    GFDL01010253    JAV24792.1    DS232020    EDS32140.1    MCFN01000062    OXB66522.1    AWGT02000046    OXB80629.1    PPHD01078481    POI20758.1    AAQR03116380    AK005756    BC028657    AADN05000150    AABR07051243    CH474001    EDL93563.1    GFFW01004515    JAV40273.1    GBHO01031190    GBHO01031189    GBHO01031188    GBHO01031184    GBHO01003880    JAG12414.1    JAG12415.1    JAG12416.1    JAG12420.1    JAG39724.1    GAPW01006071    JAC07527.1    AGTP01090703    AMQN01011090    KB308677    ELT97046.1    BC108196    UYRR01034292    VDK60731.1    GDAI01001059    JAI16544.1   

Proteomes

UP000005204    UP000218220    UP000037510    UP000007151    UP000053268    UP000053240    + More
UP000075900    UP000095301    UP000075920    UP000076408    UP000075901    UP000069272    UP000075883    UP000005203    UP000075840    UP000261500    UP000075886    UP000075885    UP000075884    UP000075880    UP000037069    UP000001819    UP000075903    UP000075902    UP000075882    UP000076407    UP000007062    UP000075881    UP000261480    UP000028760    UP000007798    UP000008744    UP000268350    UP000002852    UP000242457    UP000069940    UP000249989    UP000001075    UP000273346    UP000002280    UP000092553    UP000008820    UP000002320    UP000091820    UP000198323    UP000198419    UP000005225    UP000000589    UP000078200    UP000000539    UP000002494    UP000261520    UP000005215    UP000233160    UP000007635    UP000265180    UP000001038    UP000261560    UP000014760    UP000009136    UP000036680    UP000189706    UP000265200   

PRIDE

Q2F5N5    H9JVD0    Q9DAK9    D3ZP47    Q32PA4   

Pfam

PF05005   Ocnus

Interpro

IPR038596   Janus_sf        + More
IPR007702   Janus       
IPR028441   PHPT1       

Gene 3D

3.50.20.20    

ProteinModelPortal

Q2F5N5   H9JVD0   A0A1E1VX92   A0A2H1VDJ4   A0A2W1BK75   A0A2A4JLE7   + More
S4PGJ4   A0A0L7L2G8   A0A212F5L1   A0A194Q4N4   A0A0N1PGL2   A0A0N1PI35   A0A182R4T0   A0A1I8NB48   A0A1B6LYP8   A0A2M4CZN2   A0A0V0GDK6   A0A182VWL1   A0A182YHG7   A0A182T9L2   A0A1B6H1Q8   A0A2M4AY21   A0A069DP21   A0A2M3ZDK6   A0A182FNZ3   A0A2M4C3L3   A0A336MDK8   A0A182MKI6   A0A088ACD4   A0A2M4AY66   A0A182HZZ2   A0A3B3U8L0   A0A182Q8C2   A0A182P575   A0A182N5U6   A0A182ILD5   A0A0K8THC0   A0A0A9ZD48   A0A0L0CHZ4   I5AMV9   P54364   A0A0P4VLC5   R4FMN8   A0A023F860   A0A182V6Q2   A0A182TJU1   A0A182LR35   A0A182X0A2   Q7PUI9   A0A224XWS2   A0A2M4CTP6   A0A1B6HP61   A0A1S4F7C0   A0A182JVI0   A0A3B3WX09   A0A087X7T5   A0A087X5G2   B4NJJ3   B4GNH7   D0QWR6   U5EVH9   A0A0S7LEG5   A0A146R1V4   A0A3B0K7G7   A0A147A8G3   M3ZLH2   A0A2A3EHH3   A0A182G4V8   G3IHB0   F6WVK9   A0A0M4F3P7   Q17D02   A0A1Q3FBA0   B0WP95   A0A1A9WT60   A0A226NGC1   A0A226PMI4   A0A2P4S9G9   H0XUK7   Q9DAK9   A0A1A9VDH0   A0A1D5PWG8   D3ZP47   A0A3B4ANQ6   A0A250Y9L6   A0A3B4AME5   A0A0A9X5P1   A0A023EDZ0   I3NEJ4   A0A2K6EIY3   G3Q237   A0A3P9K6C4   A0A3B3H9F4   A0A3B3C695   R7U055   Q32PA4   A0A0M3KB29   A0A1U7R1F2   A0A3P9JMV2   A0A0K8TQA2  

PDB

2NMM     E-value=5.35572e-26,     Score=286

KEGG

692960    K01112 phosphohistidine phosphatase [EC:3.9.1.3] | (RefSeq) phosphohistidine phosphatase

GO

GO:0035971   GO:0005829   GO:0101006   GO:0007548   GO:0030154   GO:2000249   GO:2000984   GO:0050860   GO:2000147   GO:0019855   GO:0044325   GO:0051350   GO:0006470   GO:0035774  

PANTHER

PTHR12258   PTHR12258:SF10  

Subcellular location

Cytoplasm  

Length:

154

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00038

Exp number, first 60 AAs:

0.00038

Total prob of N-in:

0.01367

outside

1  -  154

 

 

Pi

214.336827

Theta

161.755598

Tajima's D

0.973545

CLR

0.007425

CSRT

0.654167291635418

Interpretation

Uncertain