Gene

KWMTBOMO02375

Pre Gene Modal

BGIBMGA013546

Annotation

PREDICTED:_phospholipid_scramblase_2-like_[Bombyx_mori]

Location

Bomo_Chr5(-):628433-640023      View in EpiBrowser

Full name

Phospholipid scramblase      

Location in the cell

Cytoplasmic   Reliability : 1.4 Nuclear   Reliability : 1.149

CDS

ATGGCAACTTCGGCAATTTATGAAACTGCACCTCTGGGAATCCAACAGCTGATATCCTTAAGTAGCTTGAGGATCCAACAAAAGAAGACCCTTTGCGTCGGCAGCGAGTATACCGTGCTGAATGAAGACGGCGAAGAGATCCTTTACGGGAAGGAAGATGCCGCGGTCCTGAGTACGCTGTTCAGCGGGAAGCATCGTTCCTTCAACATGCACATTGTGGATAGTCAAGAAAATATGGTGATATTCCTTCGGCGGCCTCATACCTTGGGGCTGGACAAACTCGAGGTGAGAGTTGACAACGTCCTGGTCAGCATAGTGCGCCCTCAGCCGACATTCGTGAAGCCGGTGTTCAGCATCAACGACGCATCAGATAAACCGGTCCTTAGGGTCAAAGGCAAGCATTGTACCAGTGCAAATCACGAATATGAGGTGTTAGCGGTCAACAAAGAACGCATCGGTGGTATCAAGAAGCACGGAGCCGGCGTCGTGACCGAAATATGCACCAGTCATTATTACATCCAGTTCCCGGCCGACTTACATGTCGATTACAAAGCTGCTTTACTCGCCACTTGCTTCTTGATCGAATATATGTTCTTCGAAAAATGA

Protein

MATSAIYETAPLGIQQLISLSSLRIQQKKTLCVGSEYTVLNEDGEEILYGKEDAAVLSTLFSGKHRSFNMHIVDSQENMVIFLRRPHTLGLDKLEVRVDNVLVSIVRPQPTFVKPVFSINDASDKPVLRVKGKHCTSANHEYEVLAVNKERIGGIKKHGAGVVTEICTSHYYIQFPADLHVDYKAALLATCFLIEYMFFEK

Description

May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

Cofactor

Ca(2+)

Similarity

Belongs to the phospholipid scramblase family.

Uniprot

H9JVI3   A0A194QAB6   A0A2A4J8J9   A0A2W1BJ50   A0A2H1WX23   A0A2H1VYI8   + More
A0A212ERV1   A0A2M4CJ13   A0A2R7VYL5   A0A182M5Q3   A0A2A4J9L6   A0A2M3ZCD7   A0A182PN68   A0A2M4AMB1   A0A2M4AMH4   A0A2M4CRV1   A0A2M4AMK6   A0A2M4BT70   A0A2M4CT89   A0A182FF13   A0A084W2Y9   A0A182JKF2   A0A182H417   A0A1B6E985   A0A182KDU7   A0A1Y1LD75   W5JP83   A0A182WKA7   A0A182QML1   A0A182Y0X4   A7UTQ3   A0A182RN38   A0A182NM01   A0A182U4C8   E9GIA2   A0A182XIM0   A0A2C9GKK3   Q7PIS7   A0A182HM25   A7UTQ2   A0A182LJJ9   A0A023EP48   A0A182V3N8   A0A1Y1LB05   T1IB30   A0A0V0G640   A0A1S4FR97   Q16S90   B0WES2   A0A2W1BEL3   A0A1Q3FYP9   A0A2A4JBK1   A0A0P4VUN0   A0A1Q3G455   A0A1Q3G454   A0A069DSP2   A0A1B6J1R9   A0A1Q3G442   A0A1B6LTY2   A0A1B6LRE2   A0A1Q3G488   A0A224XTJ7   A0A0A9XAE0   A0A067QG92   A0A1W4WQ33   A0A1B6HDV9   T1K9R0   A0A0P6CLZ2   E0VXM0   A0A0P5SL04   A0A0P6CRD8   D6W8A6   A0A0P5S6U7   A0A2S2NZP4   T1K9Q9   N6TYF6   A0A1W4WF47   T1K9R3   A0A0P4WDV5   A0A0P5YAX0   A0A1L8DKT2   A0A1B6DDL0   A0A1B6BX50   A0A0P4WMS9   U5EVB8   A0A2J7R027   A0A0P6ESC2   A0A2H1W112   T1K9Q0   E9GIA0   E4WX33   U4TUV2   A0A2J7R040   A0A2J7R038   A0A336LIQ1   T1K9Q1   X1XPY5   A0A1B0CJF4   A2BEN3  

Pubmed

19121390    26354079    28756777    22118469    24438588    26483478    + More
28004739    20920257    23761445    25244985    12364791    14747013    17210077    21292972    20966253    24945155    17510324    27129103    26334808    25401762    26823975    24845553    20566863    18362917    19820115    23537049    21097902    23594743   

EMBL

BABH01040486    BABH01040487    BABH01040488    KQ459465    KPJ00356.1    NWSH01002372    + More
PCG68447.1    KZ150157    PZC72760.1    ODYU01011703    SOQ57613.1    ODYU01005243    SOQ45910.1    AGBW02012923    OWR44205.1    GGFL01001174    MBW65352.1    KK854129    PTY11780.1    AXCM01002240    PCG68446.1    GGFM01005377    MBW26128.1    GGFK01008615    MBW41936.1    GGFK01008675    MBW41996.1    GGFL01003869    MBW68047.1    GGFK01008689    MBW42010.1    GGFJ01007145    MBW56286.1    GGFL01003870    MBW68048.1    ATLV01019732    KE525278    KFB44583.1    JXUM01108608    KQ565247    KXJ71181.1    GEDC01002799    JAS34499.1    GEZM01060886    JAV70838.1    ADMH02000550    ETN65911.1    AXCN02000941    AAAB01008960    EDO63675.1    GL732546    EFX80805.1    APCN01004326    APCN01004327    EAA44031.4    EDO63674.1    GAPW01002366    JAC11232.1    GEZM01060885    JAV70839.1    ACPB03021686    GECL01002646    JAP03478.1    CH477680    EAT37325.1    DS231911    EDS45835.1    PZC72761.1    GFDL01002387    JAV32658.1    NWSH01002038    PCG69341.1    GDKW01000186    JAI56409.1    GFDL01000464    JAV34581.1    GFDL01000462    JAV34583.1    GBGD01002138    JAC86751.1    GECU01014582    JAS93124.1    GFDL01000463    JAV34582.1    GEBQ01012851    JAT27126.1    GEBQ01013755    JAT26222.1    GFDL01000466    JAV34579.1    GFTR01005127    JAW11299.1    GBHO01025937    GBHO01025936    GDHC01020916    GDHC01012357    GDHC01004641    JAG17667.1    JAG17668.1    JAP97712.1    JAQ06272.1    JAQ13988.1    KK853500    KDR07158.1    GECU01034927    GECU01013232    JAS72779.1    JAS94474.1    CAEY01001892    GDIQ01089295    JAN05442.1    DS235833    EEB18126.1    GDIQ01091689    JAL60037.1    GDIQ01089294    JAN05443.1    KQ971307    EFA10920.2    GDIQ01091688    JAL60038.1    GGMR01009913    MBY22532.1    APGK01047306    KB741077    ENN74355.1    CAEY01001893    GDRN01078337    GDRN01078336    JAI62597.1    GDIP01060512    JAM43203.1    GFDF01007001    JAV07083.1    GEDC01013511    GEDC01011097    JAS23787.1    JAS26201.1    GEDC01031674    GEDC01011741    JAS05624.1    JAS25557.1    GDRN01078338    JAI62596.1    GANO01001947    JAB57924.1    NEVH01008299    PNF34192.1    GDIQ01071866    JAN22871.1    ODYU01005650    SOQ46717.1    EFX80807.1    FN653018    FN654894    CBY21925.1    CBY37071.1    KB631602    ERL84562.1    PNF34190.1    PNF34198.1    UFQS01000007    UFQT01000007    SSW97099.1    SSX17485.1    ABLF02035891    AJWK01014544    AJWK01014545    AJWK01014546    BX119902   

Proteomes

UP000005204    UP000053268    UP000218220    UP000007151    UP000075883    UP000075885    + More
UP000069272    UP000030765    UP000075880    UP000069940    UP000249989    UP000075881    UP000000673    UP000075920    UP000075886    UP000076408    UP000007062    UP000075900    UP000075884    UP000075902    UP000000305    UP000076407    UP000075840    UP000075882    UP000075903    UP000015103    UP000008820    UP000002320    UP000027135    UP000192223    UP000015104    UP000009046    UP000007266    UP000019118    UP000235965    UP000030742    UP000007819    UP000092461    UP000000437   

PRIDE

H9JVI3   

Pfam

PF03803   Scramblase        + More
PF04112   Mak10

Interpro

IPR025659   Tubby-like_C        + More
IPR005552   Scramblase       
IPR038595   LOR_sf       
IPR007244   Naa35/Mak10       

SUPFAM

SSF54518   SSF54518       

Gene 3D

3.20.90.20    

ProteinModelPortal

H9JVI3   A0A194QAB6   A0A2A4J8J9   A0A2W1BJ50   A0A2H1WX23   A0A2H1VYI8   + More
A0A212ERV1   A0A2M4CJ13   A0A2R7VYL5   A0A182M5Q3   A0A2A4J9L6   A0A2M3ZCD7   A0A182PN68   A0A2M4AMB1   A0A2M4AMH4   A0A2M4CRV1   A0A2M4AMK6   A0A2M4BT70   A0A2M4CT89   A0A182FF13   A0A084W2Y9   A0A182JKF2   A0A182H417   A0A1B6E985   A0A182KDU7   A0A1Y1LD75   W5JP83   A0A182WKA7   A0A182QML1   A0A182Y0X4   A7UTQ3   A0A182RN38   A0A182NM01   A0A182U4C8   E9GIA2   A0A182XIM0   A0A2C9GKK3   Q7PIS7   A0A182HM25   A7UTQ2   A0A182LJJ9   A0A023EP48   A0A182V3N8   A0A1Y1LB05   T1IB30   A0A0V0G640   A0A1S4FR97   Q16S90   B0WES2   A0A2W1BEL3   A0A1Q3FYP9   A0A2A4JBK1   A0A0P4VUN0   A0A1Q3G455   A0A1Q3G454   A0A069DSP2   A0A1B6J1R9   A0A1Q3G442   A0A1B6LTY2   A0A1B6LRE2   A0A1Q3G488   A0A224XTJ7   A0A0A9XAE0   A0A067QG92   A0A1W4WQ33   A0A1B6HDV9   T1K9R0   A0A0P6CLZ2   E0VXM0   A0A0P5SL04   A0A0P6CRD8   D6W8A6   A0A0P5S6U7   A0A2S2NZP4   T1K9Q9   N6TYF6   A0A1W4WF47   T1K9R3   A0A0P4WDV5   A0A0P5YAX0   A0A1L8DKT2   A0A1B6DDL0   A0A1B6BX50   A0A0P4WMS9   U5EVB8   A0A2J7R027   A0A0P6ESC2   A0A2H1W112   T1K9Q0   E9GIA0   E4WX33   U4TUV2   A0A2J7R040   A0A2J7R038   A0A336LIQ1   T1K9Q1   X1XPY5   A0A1B0CJF4   A2BEN3  

KEGG

101741722    no KO assigned | (RefSeq) phospholipid scramblase 2-like

GO

GO:0017128   GO:0017121   GO:0016021   GO:0031417   GO:0017196  

PANTHER

PTHR23248  

Length:

201

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.47581

Exp number, first 60 AAs:

0.0248

Total prob of N-in:

0.18376

outside

1  -  201

 

 

Pi

131.402053

Theta

151.818139

Tajima's D

0.4756

CLR

1.860855

CSRT

0.500824958752062

Interpretation

Uncertain