Gene

KWMTBOMO02351

Pre Gene Modal

BGIBMGA014411

Annotation

PREDICTED:_DNA_repair_protein_complementing_XP-A_cells_homolog_[Papilio_machaon]

Location

Bomo_Chr5(+):49626-57080      View in EpiBrowser

Full name

DNA repair protein complementing XP-A cells homolog      

Alternative Name

Xeroderma pigmentosum group A-complementing protein homolog

Location in the cell

Nuclear   Reliability : 2.484

CDS

ATGGACAGCGATGAAGTAAACATATCCCAAGAGAAAAAAAACAAATTAACTGCCACACAGCTTGCCCGCATCGAACGGCAACGTCTACGGGCCAGAGCACTGCGTGACTCTCGACCCTTGCTGAGAAATGAAGATAAACCCGCACCAGTACCCACTCTTGGATGCGGAGGTGGATTCCTGCCAGAAGAGACACACGAGCTGAATGCAGTGGTTGCGCCTTGCGCTCCCCTCGTGCACCCCGGCCACCAACCCCATTGTCTTCATTGCGGACGACCCTTTCCACAATCTTTCCTCTATGACAACTTTGACTATTCAATTTGTGACGAGTGTAGGGATACTGAAGGAGAACACGCTCTCATGACACGCACAGAGGCCAAGAACGAGTACCTTTTGAAGGATTGCGACTTGGACAGTCGAGAACCCCCTTTGCGATGTTTGCGACGCCGCAACCCGCACAGCGCTCGGTTCGGCGACATGCGGTTGTACCTGCGCGCGCAGCTGCAGGAGCGCGCGCTGCAGGTGTGGGGCTCGCACGCGGCGCTGGACGAGGAGCGGGCGCGGCGGGAGGGCGCGCGGGCGGCGGGGGCGGGGCGGCGCGCAGTCCGCCGCCTGCGCGCGCTGCGGATGGACGTGCGCTCGAGTCTGTACACGCCCCAGCGCGCCGCACACGAGCACGAGTTCGGTCCCGAGACGCACGATGCCCGCGCCGACGTCTACTCCCGCTCCTGCCTCTCCTGCGGACACACCCAGTCCTATGAGAAGATGTGA

Protein

MDSDEVNISQEKKNKLTATQLARIERQRLRARALRDSRPLLRNEDKPAPVPTLGCGGGFLPEETHELNAVVAPCAPLVHPGHQPHCLHCGRPFPQSFLYDNFDYSICDECRDTEGEHALMTRTEAKNEYLLKDCDLDSREPPLRCLRRRNPHSARFGDMRLYLRAQLQERALQVWGSHAALDEERARREGARAAGAGRRAVRRLRALRMDVRSSLYTPQRAAHEHEFGPETHDARADVYSRSCLSCGHTQSYEKM

Description

Involved in DNA excision repair. Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region (By similarity).

Similarity

Belongs to the XPA family.

Keywords

Complete proteome   DNA damage   DNA repair   DNA-binding   Metal-binding   Nucleus   Reference proteome   Zinc   Zinc-finger  

Feature

chain  DNA repair protein complementing XP-A cells homolog

Uniprot

A0A2H1W8R9   A0A0N1IF35   A0A212FAP1   A0A1I8NXF5   A0A1B6FML9   B4JNH0   + More
A0A1I8M3I0   A0A1W4UPD1   Q29I43   A0A0L0C301   B4HA92   B4M7L9   A0A182KCR8   A0A3P8W0I1   A0A1S3IZ50   A0A1S3IZN8   A0A182MIZ7   A0A182WIN9   A0A0Q9WEY0   A0A1B6JD02   A0A2Z5TRL6   A0A1B6L8J1   A0A182XZ33   A0A2P2I554   A0A1A9WHV3   W8C6W9   B4Q0F6   B3MSL8   A0A3B0JDJ3   A0A212EW90   H0RNH2   P28518   W5JI56   D3PFI1   A0A1A8EU74   B4I126   A0A0K8TVY6   A0A182IZW4   A0A0L7RBJ7   A0A1A8CYN2   A0A1A8B7Z2   A0A1A8JHS4   A0A034UX17   A0A2I4CG41   B3NSU2   W5JUE2   A0A2A3EUZ7   A0A1A8EBS3   A0A1A8RBW5   A0A154PMY7   E0VXW3   A0A1A8RGG6   A0A182P3R2   A0A182UQY2   A0A2M4BWM6   A0A0A1X2R5   A0A2J7R3S2   A0A1A8MEF5   A0A2M4BWH4   A0A182TYM8   A0A182I3I5   A0A182X3I5   A0A310SI10   A0A0M5J178   A0A0A1X1X9   A0A1A9ZRE5   B4L6M6   A0A088AJ88   A0A182KRM2   C3YQX9   I3KH57   A0A1B0FY38   D6WKJ8   A0A2T7NEJ7   A0A084VEZ3   A0A067QWU0   A0A1S4EEH0   A0A3B4EVF8   Q7QJL3   A0A2G8LLN3   A0A3P8N6D4   A0A1A9V625   A0A182NH84   A0A1A7XNW5   A0A3P9I8T6   A0A182R4Q7   A0A1A7Y0B6   A0A3P9B0M4   U5EXT0   A0A147A513   A0A0S7LP57   E2B616   A0A3B3ZEZ4   A0A182QNJ1   A0A151HYY1   A0A1W4X6C9   A0A158NWB2   H3BX47   H3DPW4   F4X4S6  

Pubmed

26354079    22118469    17994087    25315136    15632085    26108605    + More
24487278    26760975    25244985    24495485    17550304    1764072    7673233    10731132    12537572    10731137    20920257    23761445    25348373    20566863    25830018    20966253    18563158    25186727    18362917    19820115    24438588    24845553    12364791    14747013    17210077    29023486    17554307    20798317    25463417    21347285    15496914    21719571   

EMBL

ODYU01007043    SOQ49460.1    KQ460401    KPJ14970.1    AGBW02009439    OWR50806.1    + More
GECZ01018347    JAS51422.1    CH916371    EDV92263.1    CH379064    EAL31563.1    JRES01000960    KNC26728.1    CH479239    EDW37486.1    CH940653    EDW62786.1    AXCM01007945    KRF80791.1    GECU01019471    GECU01010708    JAS88235.1    JAS96998.1    FX985852    BBA93739.1    GEBQ01020022    JAT19955.1    IACF01003544    LAB69158.1    GAMC01000887    JAC05669.1    CM000162    EDX01240.1    CH902622    EDV34773.1    OUUW01000003    SPP78202.1    AGBW02012041    OWR45762.1    BT132894    AEV23918.1    D31893    D31892    AE014298    AL033125    ADMH02001474    ETN62454.1    BT120387    ADD16467.1    HAEB01003880    SBQ50407.1    CH480819    EDW53207.1    GDHF01033675    JAI18639.1    KQ414617    KOC68239.1    HADZ01020009    SBP83950.1    HADY01024130    HAEJ01016854    SBP62615.1    HAED01022720    HAEE01005649    SBR09487.1    GAKP01023437    JAC35521.1    CH954180    EDV45772.1    ADMH02000120    ETN67766.1    KZ288185    PBC34969.1    HAEA01014571    SBQ43051.1    HAEH01015603    SBS03172.1    KQ434977    KZC12824.1    DS235841    EEB18219.1    HAEI01008350    SBS04777.1    GGFJ01008335    MBW57476.1    GBXI01008663    JAD05629.1    NEVH01007818    PNF35483.1    HAEF01014023    HAEG01007645    SBR55182.1    GGFJ01008268    MBW57409.1    APCN01000213    KQ768636    OAD53092.1    CP012528    ALC49268.1    GBXI01009614    JAD04678.1    CH933812    EDW06022.1    GG666544    EEN57320.1    AERX01023435    AJVK01031199    KQ971342    EFA03569.1    PZQS01000013    PVD19565.1    ATLV01012357    KE524785    KFB36537.1    KK852921    KDR13782.1    AAAB01008807    EAA04751.3    MRZV01000040    PIK61145.1    HADW01018288    SBP19688.1    HADX01001534    SBP23766.1    GANO01002389    JAB57482.1    GCES01012717    JAR73606.1    GBYX01157920    GBYX01157915    GBYX01157914    GBYX01157913    JAO91272.1    GL445900    EFN88877.1    AXCN02000893    KQ976730    KYM76453.1    ADTU01027864    GL888679    EGI58499.1   

Proteomes

UP000053240    UP000007151    UP000095300    UP000001070    UP000095301    UP000192221    + More
UP000001819    UP000037069    UP000008744    UP000008792    UP000075881    UP000265120    UP000085678    UP000075883    UP000075920    UP000076408    UP000091820    UP000002282    UP000007801    UP000268350    UP000000803    UP000000673    UP000001292    UP000075880    UP000053825    UP000192220    UP000008711    UP000242457    UP000076502    UP000009046    UP000075885    UP000075903    UP000235965    UP000075902    UP000075840    UP000076407    UP000092553    UP000092445    UP000009192    UP000005203    UP000075882    UP000001554    UP000005207    UP000092462    UP000007266    UP000245119    UP000030765    UP000027135    UP000079169    UP000261460    UP000007062    UP000230750    UP000265100    UP000078200    UP000075884    UP000265200    UP000075900    UP000265160    UP000265000    UP000008237    UP000261520    UP000075886    UP000078540    UP000192223    UP000005205    UP000007303    UP000007755   

PRIDE

P28518   

Pfam

PF05181   XPA_C        + More
PF01286   XPA_N

Interpro

IPR037129   XPA_sf        + More
IPR000465   XPA       
IPR022652   Znf_XPA_CS       
IPR009061   DNA-bd_dom_put_sf       
IPR022656   XPA_C       
IPR022658   XPA_CS       

SUPFAM

SSF46955   SSF46955       

Gene 3D

3.90.530.10    

ProteinModelPortal

A0A2H1W8R9   A0A0N1IF35   A0A212FAP1   A0A1I8NXF5   A0A1B6FML9   B4JNH0   + More
A0A1I8M3I0   A0A1W4UPD1   Q29I43   A0A0L0C301   B4HA92   B4M7L9   A0A182KCR8   A0A3P8W0I1   A0A1S3IZ50   A0A1S3IZN8   A0A182MIZ7   A0A182WIN9   A0A0Q9WEY0   A0A1B6JD02   A0A2Z5TRL6   A0A1B6L8J1   A0A182XZ33   A0A2P2I554   A0A1A9WHV3   W8C6W9   B4Q0F6   B3MSL8   A0A3B0JDJ3   A0A212EW90   H0RNH2   P28518   W5JI56   D3PFI1   A0A1A8EU74   B4I126   A0A0K8TVY6   A0A182IZW4   A0A0L7RBJ7   A0A1A8CYN2   A0A1A8B7Z2   A0A1A8JHS4   A0A034UX17   A0A2I4CG41   B3NSU2   W5JUE2   A0A2A3EUZ7   A0A1A8EBS3   A0A1A8RBW5   A0A154PMY7   E0VXW3   A0A1A8RGG6   A0A182P3R2   A0A182UQY2   A0A2M4BWM6   A0A0A1X2R5   A0A2J7R3S2   A0A1A8MEF5   A0A2M4BWH4   A0A182TYM8   A0A182I3I5   A0A182X3I5   A0A310SI10   A0A0M5J178   A0A0A1X1X9   A0A1A9ZRE5   B4L6M6   A0A088AJ88   A0A182KRM2   C3YQX9   I3KH57   A0A1B0FY38   D6WKJ8   A0A2T7NEJ7   A0A084VEZ3   A0A067QWU0   A0A1S4EEH0   A0A3B4EVF8   Q7QJL3   A0A2G8LLN3   A0A3P8N6D4   A0A1A9V625   A0A182NH84   A0A1A7XNW5   A0A3P9I8T6   A0A182R4Q7   A0A1A7Y0B6   A0A3P9B0M4   U5EXT0   A0A147A513   A0A0S7LP57   E2B616   A0A3B3ZEZ4   A0A182QNJ1   A0A151HYY1   A0A1W4X6C9   A0A158NWB2   H3BX47   H3DPW4   F4X4S6  

PDB

1D4U     E-value=3.67206e-27,     Score=300

KEGG

101744655    K10847 DNA-repair protein complementing XP-A cells | (RefSeq) DNA repair protein complementing XP-A

PATHWAY

03420    Nucleotide excision repair - Bombyx mori (domestic silkworm)

GO

GO:0005634   GO:0003684   GO:0006289   GO:0046872   GO:0000110   GO:0070914   GO:0006284   GO:0000715   GO:1901255   GO:0033683   GO:0004713   GO:0005515   GO:0005488   GO:0004518   GO:0006281   GO:0048384  

PANTHER

PTHR10142  

Subcellular location

Nucleus  

Length:

255

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0

Exp number, first 60 AAs:

0

Total prob of N-in:

0.07689

outside

1  -  255

 

 

Pi

17.676903

Theta

5.715372

Tajima's D

-2.274518

CLR

348.074641

CSRT

0.00249987500624969

Interpretation

Possibly Positive selection