Gene

KWMTBOMO02347  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA003753

Annotation

PREDICTED:_signal_transducing_adapter_molecule_2_[Bombyx_mori]

Location

Bomo_Chr4(-):18630858-18638561      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 1.584 Nuclear   Reliability : 1.597

CDS

ATGGGAATATTTGGCACTTCCTCGCCTTTTGATCAAGATGTTGAACGCGCAACGAGTGAAAATAACACCAGCGAGGAGTGGGGACTGATCATGGAGATATGTGATCGCGCCGGTGCATCTTCTACCAGTGCGAAGGAGTGTCTCCGTGCCGTCATGCGGCGCTTGGCGCATCCCGACCCACACGTACAGGTTCACGCCGCCACACTGCTCGACGCCTGCGTTGCAAATTGCGGTCGTTTCTTCCACCTGGAAGTCGCCTCGCGAGACTTCGAGACCGAGTTCCGGCGCCTGCTGTCTCGCGCGCAGCCTCCTGTCGCCGCTCGTCTCCGCGCCCTGCTCCGCAAGTGGGCCGAGGGCGAGTTTCGCGACGACCCGCAGCTCGACCTCATCCCGGCGCTGCACGCGCGCCTCCCGACCACTGAGGCTCCCGCGGCCGCGGCCCCGAGCCCGGCGCCGGCCGCGCAGCGCGAGCAGGACGAGCTGGCGCGCGCCATTGCTCTGTCTCTGCGAGAGAGTCAGCCGGCGCCGGGCCCGACCTCCGCGGCGGCCCCCGGCGCCGGCTCCACGCTGTACCCGCGAGTGGAGACCGCGCCGGCGCGCCCTGTGCGCGCTCTCTACGATTTCGAAGCAGCGGAAGATAACGAACTTACTTTTCTAGCTGGCGAAATTGTTCACGTGACCGACTCGAGTGATCCGAACTGGTGGAAAGGGTACAACGATCGCGGCGAGGGACTGTTTCCTGCCAACTTTGTGACGGAGGAACTGGCTGTGGGCGCCCCGGCCGCCGCCGCTGACGAGCCTCCAGCCGAGCTGGCCGCGACCGGCGCCGACGAGGCGGACGGCATCGACGAGGCGGCGCTGGACGAGGCACTGGCCCTGCTGCACGAGGCGGACCCGGCGTGCGCGGGCTCGGCGGGCGAGGACGCGCGGCTGGCGCGGCTGGAGGCGCGCGCGGCCGCCACCGGCGCGCTCGTGGACGCGGCGCTGGAGCGAGCCGACCGCCGCCACGCTCGCCTCACGCAGCTCAGCGCCGACCTGGTGGACGCGCTCAACCTCTACCACACGCTGATGCGCGAGCCGCACTACGCGCCGCACTACCCGCCCGCGCACCCGCCCGCACACCCGCCGGCGCACCCGCGCTGCTGA

Protein

MGIFGTSSPFDQDVERATSENNTSEEWGLIMEICDRAGASSTSAKECLRAVMRRLAHPDPHVQVHAATLLDACVANCGRFFHLEVASRDFETEFRRLLSRAQPPVAARLRALLRKWAEGEFRDDPQLDLIPALHARLPTTEAPAAAAPSPAPAAQREQDELARAIALSLRESQPAPGPTSAAAPGAGSTLYPRVETAPARPVRALYDFEAAEDNELTFLAGEIVHVTDSSDPNWWKGYNDRGEGLFPANFVTEELAVGAPAAAADEPPAELAATGADEADGIDEAALDEALALLHEADPACAGSAGEDARLARLEARAAATGALVDAALERADRRHARLTQLSADLVDALNLYHTLMREPHYAPHYPPAHPPAHPPAHPRC

Cofactor

Mn(2+)

Similarity

Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.

Uniprot

A0A1B0D6L3   A0A1L8DLC6   A0A1L8DLD0   A0A1B6FKN5   A0A1B6DGK9   A0A0L0CFQ5   + More
A0A1Y1K3B2   E2B1M2   A0A2M4AKV5   A0A1B6HBS4   A0A026VYR4   A0A2M3Z506   A0A1Y9G9P8   W5JT34   A0A158NT64   A0A195F4K2   A0A2M4AAZ2   F4WXS0   A0A195BW28   A0A195D505   A0A088AM41   B3N517   A0A2M4BEQ9   A0A2M4BFE6   A0A2M4BEQ8   B4P133   E2C6G2   A0A1I8MJL9   A0A1Y9J0E7   A0A182UGU5   A0A182IIF0   Q9XTL2   A0A1W4VSZ2   B4Q9V5   B4HWX3   A0A182WHH7   A0A182IIY0   E9GPB3   A0A084VL60   A0A182NUV8   A0A0N0BKK7   A0A1S4F152   E0W250   A0A0P6C633   A0A0P4ZJM0   A0A0P6GCC4   A0A164PUD8   A0A182GMV9   T1J9T9   A0A1S3JT95   A0A182QV08   A0A2R5L4M8   A0A1S3H626   A0A0T6BDD2   A0A1Z5KWM7   L7M5X7   A0A1S3H3N8   A0A1Z5L5P8   A0A224Z6L8   A0A131Z335   A0A293MWX2   A0A0B4PMI2   A0A0K2UCC5   A0A131XKD6   A0A023GKB7   A0A1S3H3J5   U5EWZ4   A0A1J1IS95   A0A1S3JSE3   A0A1S3H534   A0A131XZX1   A0A1Q3FBC5   T1K607   A0A087TMT5   A0A151WTD0   A0A226EHX6   A0A0P5BGS6   A0A1Z5KXE1   A0A1Z5L6R6  

Pubmed

26108605    28004739    20798317    24508170    30249741    20920257    + More
23761445    21347285    21719571    17994087    17550304    25315136    10231582    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    22936249    21292972    24438588    17510324    20566863    26483478    28528879    25576852    28797301    26830274    28049606   

EMBL

AJVK01003742    AJVK01003743    GFDF01006811    JAV07273.1    GFDF01006816    JAV07268.1    + More
GECZ01019206    JAS50563.1    GEDC01012475    JAS24823.1    JRES01000438    KNC31243.1    GEZM01094100    JAV55933.1    GL444953    EFN60378.1    GGFK01008105    MBW41426.1    GECU01035576    JAS72130.1    KK107570    QOIP01000005    EZA48805.1    RLU22485.1    GGFM01002845    MBW23596.1    ADMH02000447    ETN66438.1    ADTU01025608    KQ981805    KYN35510.1    GGFK01004635    MBW37956.1    GL888427    EGI60998.1    KQ976403    KYM92173.1    KQ976842    KYN07952.1    CH954177    EDV58962.1    GGFJ01002398    MBW51539.1    GGFJ01002397    MBW51538.1    GGFJ01002399    MBW51540.1    CM000157    EDW88008.1    GL453151    EFN76465.1    APCN01000751    AF121359    AF121361    AE014134    BT006014    AAD34350.1    AAD37503.1    AAF53027.1    AAO74697.1    CM000361    CM002910    EDX04622.1    KMY89640.1    CH480818    EDW52518.1    GL732556    EFX78711.1    ATLV01014417    KE524970    KFB38704.1    KQ435698    KOX80738.1    DS235874    EEB19706.1    GDIP01012926    JAM90789.1    GDIP01216086    JAJ07316.1    GDIQ01036847    JAN57890.1    LRGB01002559    KZS07148.1    JXUM01075151    KQ562872    KXJ74951.1    JH431978    AXCN02000748    GGLE01000322    MBY04448.1    LJIG01001602    KRT85338.1    GFJQ02007510    JAV99459.1    GACK01005574    JAA59460.1    GFJQ02004227    JAW02743.1    GFPF01011765    MAA22911.1    GEDV01002850    JAP85707.1    GFWV01020604    MAA45332.1    KF828776    AIT40218.1    HACA01018527    HACA01018528    CDW35889.1    GEFH01001916    JAP66665.1    GBBM01001049    JAC34369.1    GANO01000324    JAB59547.1    CVRI01000058    CRL02578.1    GEFM01004096    JAP71700.1    GFDL01010174    JAV24871.1    CAEY01001591    KK115946    KFM66424.1    KQ982757    KYQ51150.1    LNIX01000003    OXA57303.1    GDIP01184840    JAJ38562.1    GFJQ02007509    JAV99460.1    GFJQ02004226    JAW02744.1   

Proteomes

UP000092462    UP000037069    UP000000311    UP000053097    UP000279307    UP000069272    + More
UP000000673    UP000005205    UP000078541    UP000007755    UP000078540    UP000078542    UP000005203    UP000008711    UP000002282    UP000008237    UP000095301    UP000076407    UP000075902    UP000075840    UP000000803    UP000192221    UP000000304    UP000001292    UP000075920    UP000075880    UP000000305    UP000030765    UP000075884    UP000053105    UP000009046    UP000076858    UP000069940    UP000249989    UP000085678    UP000075886    UP000183832    UP000015104    UP000054359    UP000075809    UP000198287   

PRIDE

Q9XTL2    L7M5X7   

Pfam

PF00790   VHS        + More
PF00018   SH3_1
PF02809   UIM
PF02536   mTERF
PF00652   Ricin_B_lectin
PF02145   Rap_GAP
PF00535   Glycos_transf_2
PF01426   BAH

Interpro

IPR008942   ENTH_VHS        + More
IPR001452   SH3_domain       
IPR002014   VHS_dom       
IPR036028   SH3-like_dom_sf       
IPR003903   UIM_dom       
IPR003690   MTERF       
IPR038538   MTERF_sf       
IPR000772   Ricin_B_lectin       
IPR035992   Ricin_B-like_lectins       
IPR001173   Glyco_trans_2-like       
IPR001478   PDZ       
IPR035974   Rap/Ran-GAP_sf       
IPR000331   Rap_GAP_dom       
IPR036034   PDZ_sf       
IPR029044   Nucleotide-diphossugar_trans       
IPR001025   BAH_dom       
IPR029616   Wge       

SUPFAM

SSF48464   SSF48464        + More
SSF50044   SSF50044       
SSF50370   SSF50370       
SSF111347   SSF111347       
SSF53448   SSF53448       
SSF50156   SSF50156       

Gene 3D

1.25.40.90     1.25.70.10     3.40.50.11210     3.90.550.10    

CDD

cd00161  RICIN

ProteinModelPortal

A0A1B0D6L3   A0A1L8DLC6   A0A1L8DLD0   A0A1B6FKN5   A0A1B6DGK9   A0A0L0CFQ5   + More
A0A1Y1K3B2   E2B1M2   A0A2M4AKV5   A0A1B6HBS4   A0A026VYR4   A0A2M3Z506   A0A1Y9G9P8   W5JT34   A0A158NT64   A0A195F4K2   A0A2M4AAZ2   F4WXS0   A0A195BW28   A0A195D505   A0A088AM41   B3N517   A0A2M4BEQ9   A0A2M4BFE6   A0A2M4BEQ8   B4P133   E2C6G2   A0A1I8MJL9   A0A1Y9J0E7   A0A182UGU5   A0A182IIF0   Q9XTL2   A0A1W4VSZ2   B4Q9V5   B4HWX3   A0A182WHH7   A0A182IIY0   E9GPB3   A0A084VL60   A0A182NUV8   A0A0N0BKK7   A0A1S4F152   E0W250   A0A0P6C633   A0A0P4ZJM0   A0A0P6GCC4   A0A164PUD8   A0A182GMV9   T1J9T9   A0A1S3JT95   A0A182QV08   A0A2R5L4M8   A0A1S3H626   A0A0T6BDD2   A0A1Z5KWM7   L7M5X7   A0A1S3H3N8   A0A1Z5L5P8   A0A224Z6L8   A0A131Z335   A0A293MWX2   A0A0B4PMI2   A0A0K2UCC5   A0A131XKD6   A0A023GKB7   A0A1S3H3J5   U5EWZ4   A0A1J1IS95   A0A1S3JSE3   A0A1S3H534   A0A131XZX1   A0A1Q3FBC5   T1K607   A0A087TMT5   A0A151WTD0   A0A226EHX6   A0A0P5BGS6   A0A1Z5KXE1   A0A1Z5L6R6  

PDB

3LDZ     E-value=3.70162e-38,     Score=397

KEGG

101742296    K04705 signal transducing adaptor molecule | (RefSeq) signal transducing adapter molecule 2

PATHWAY

04144    Endocytosis - Bombyx mori (domestic silkworm)

GO

GO:0006886   GO:0005623   GO:0051726   GO:2000274   GO:0007427   GO:0016197   GO:0042060   GO:0016322   GO:0043130   GO:0033565   GO:0006355   GO:0003690   GO:0051056   GO:0016021   GO:0030246   GO:0016757   GO:0005794   GO:0005096   GO:0006486   GO:0003682   GO:0030154   GO:0005515   GO:0005524   GO:0004713   GO:0005488   GO:0006289   GO:0004518   GO:0006281   GO:0048384  

PANTHER

PTHR12505:SF24  

Length:

381

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00064

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00114

outside

1  -  381

 

 

Pi

4.481266

Theta

16.306965

Tajima's D

-0.674837

CLR

0.991348

CSRT

0.206189690515474

Interpretation

Uncertain