Silkworm Genome Informatics Database

Gene

KWMTBOMO02346

Pre Gene Modal

BGIBMGA003802

Annotation

PREDICTED:_uncharacterized_protein_LOC101742154_[Bombyx_mori]

Location

Bomo_Chr4(+):18614402-18617336 View in EpiBrowser

Full name

Guanylate cyclase

Location in the cell

Cytoplasmic Reliability : 1.339 PlasmaMembrane Reliability : 1.079

CDS

ATGATGTTTCTCATCGACAGATCGGGTCGAATAGACATATACACGACCGCCGAGGTGCGCGACGCCGCTGAGCTGAGCAGCGTGGTGCAGCGCGCCGCGGCGGCCGAGCTGCGCGGCGTGCTGCACGTGCTGTCCCGCGCCGAGCTGCATCACCGCATCGCCACCGACAACGCTTCTTTTCTGATCTTAGACTACAAGCTGTGGGACGATCACGAACTTCTGGTCCCCGTTAGTTTTCCGGCCCGAAGTTGCGGAGAAGACGTGGAGAGTACCCGGACGGAGTTCGTCATTCACGAAGAGCTCGAAGCGTACGCTCCGATACTCTACAGCGCCGCCGAAAGGTTCGACCCGACGCCGCGGGAAGTGCGCGCAGTGCTAGACATGGCCGCGCGGCGGGGCGACGGCGACGTCGAGGAGGCGGCGTGTCAGTGGGCTGCAGAATATCCCATCAGATTTCAGTCTTGGATTCCTCAATACGACGACGACCATCATGTCTTAGTATTGCTGTGCAATGAACGCGACAATTACAATTACACACCGCTCTTCCAATTTGTCATACACAAACTTCAACAATATACGGGGCAATTAAAAATCAATATACTAATAAAAGATGAGTTAGTGAACTGTTCGAATGCGGACGATCCGCACCAAGTTTTAAACAACAAGACGCGCATGTCCAGAATATACCGCTGCATCGGCGTGGCGGCGGGCGCGGCGGACGCGGCGACGGTGGCGCGGGTCGCCCGTGACGCCGCGCTGCCGCTCGTGCTGTACGACACGCCGGCCCGGGTCCCGCCCGGCACGCGCTCGTCCGCCTGCAGCCTCGCTGACCTCGTCACTGCCATCGAGCACTTCATCGTCAAAACCGGTTGGCGACGAATAGTAACCTTATCCGAGCGAACAGAGTTTGCGGAAGCTTTCGTCTTGGCTCTAAGGTCGAGTGTAAGTTTGATAACGAAAGACATAGACTTGACCGAGAATGTGACCGAAGCGCTGAATACGGTGGAAGAACTAGACGGGCGTGTCATAATAGTGAACGCGGGCGCCGATCTGACGGCGGCAGTGGTGCGCGAAGCCGCGCAGCGCAGCTTGGACGAGCGGCGAGGGATGGCGTGGCTGGTGCGCGCCTGGGCCCCCGCGAACCCTACACCCATTCCACTGTTCTATCTAAGATGCGGATGTCGAAAGGCGGAAAACCAGTTTAACCACCCGAACGCCGCTTCGCTCGCAGACGCGGTGCTGACCCTTGGGTACGGATTCACTGCTGGTTTGATGCAGGATTACTCGGTTCGAGATGATCCAGCGGGAAGAAATCTGGAGCGCTTCTGGCAGATTTCGGACAGGATCAGCGTCGATGGCCTCTGTGAAAGTATTAAATATGAGGCGGCAGCATTGGCGAAGTCGACCGTGCTCGTGGACAAGCTTTCAGTCGACGGGAATTCAACATTAGGCATATTGATCGTGCGTGACGGCCGAGTCAGTTCTGAACCAAACGAAATGGAACCGTACGGGCGGGATGGTGAGGCTCCCTACGACGGACGCAGCAGGTGCAGCATGCCGATAGGCGACCCGTTCCATCCGCATTGCCTGGACGCACTCTGCGTCGTGGTCGGCATTCTTCTAAGTCTCGCTGTTCCGTTGTTGCTGATGGCACACCGTCACCTGGCTTCTGTTATTCGGCCCGCTAAGCTACCACCCGTCACTCAGGAGCTAACACGTTTCCTGGTCGATCCCGCTCATCTCGTGACGTACGACATCCTCGGAACCGGTAGATTCGGCCGTGTTCACCTGGGCGTATTACAGGTTCCAGGAAAAGCACCTCGCCCTGTCGCCGTCAAGTCCCTCCGGAAAGGCGCCGCTCCGGCCGAAGAAACTGAATTTCTGAATGAAGCCGTTATTATGGCGGCACTCGATCACGAGCACATTATACGCTTCGTGGGCGCGTGCGTCGCGAAGGGGCCGCCACTCGTGTTAATGGAGCACGCCTTTTTCGGAGATCTCCGAAGATACTTGCGCGAGAGGCGGCACTTCGCCGAGCAATCTGACCATCTTTCACAAGACTCGAAAGATTTCGAAGAGAGCGAACACGTGTCGGCCGAGGCGCTGACCCAGCTCGCTTCGGAGGCGGCCCTCGCCCTGGAGCACCTTGCGCGACGCGGCGTCGTCCACCGAGACGTCCGCGCCTCCAACTGCCTAGTGGACTCTAGACGACGACTGAAGCTCGGCGACTTCGGCATGGCGCGAAAGACCGATGCGACGGGCGCAGACGGAGCGGCCGAGTACGCGTGCCGGCGACGCGGCCTGTTCCCGGTGCTGTGGATGGCGCCAGAGAGCCTGAGCCGCGGCGCGTTCTCGTCGGCCTCGGACGTGTGGTCACTGGGAGTGCTGATGTTGGAGACAGTGACGCTGGGCGATCGGCCCTACGGCTCGTGGTCCCCACTGCGCGTGCTGCAACACGTGTCGAGCGGCGGACGACCCGAGCTGCCGTTCGGCGCGGCGGCGGAGGCGCGCGGCGTGGCGAGCGCATGCTGGCGCCGAGCGGCGTGCGAGCGGCCGGCGGCGGGCGAGGTGGCGCGCTACTTGCGGGACCACCCCCGCGCGCTGCGCCCGGTGCTGCGGTCGCGCGTCGCTCCCGATGCCGACAGCGGCTTCGGAGAGTCCGATCCGCCTTCCCCATAG

Protein

MMFLIDRSGRIDIYTTAEVRDAAELSSVVQRAAAAELRGVLHVLSRAELHHRIATDNASFLILDYKLWDDHELLVPVSFPARSCGEDVESTRTEFVIHEELEAYAPILYSAAERFDPTPREVRAVLDMAARRGDGDVEEAACQWAAEYPIRFQSWIPQYDDDHHVLVLLCNERDNYNYTPLFQFVIHKLQQYTGQLKINILIKDELVNCSNADDPHQVLNNKTRMSRIYRCIGVAAGAADAATVARVARDAALPLVLYDTPARVPPGTRSSACSLADLVTAIEHFIVKTGWRRIVTLSERTEFAEAFVLALRSSVSLITKDIDLTENVTEALNTVEELDGRVIIVNAGADLTAAVVREAAQRSLDERRGMAWLVRAWAPANPTPIPLFYLRCGCRKAENQFNHPNAASLADAVLTLGYGFTAGLMQDYSVRDDPAGRNLERFWQISDRISVDGLCESIKYEAAALAKSTVLVDKLSVDGNSTLGILIVRDGRVSSEPNEMEPYGRDGEAPYDGRSRCSMPIGDPFHPHCLDALCVVVGILLSLAVPLLLMAHRHLASVIRPAKLPPVTQELTRFLVDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSAEALTQLASEAALALEHLARRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGRPELPFGAAAEARGVASACWRRAACERPAAGEVARYLRDHPRALRPVLRSRVAPDADSGFGESDPPSP

Catalytic Activity

GTP = 3',5'-cyclic GMP + diphosphate

Similarity

Belongs to the protein kinase superfamily. Tyr protein kinase family.

Feature

chain Guanylate cyclase

Uniprot

H9J2R5 A0A2H1W5C3 A0A212EX59 A0A2M4A536 A0A2M4A4W5 A0A2M4A5V4 + More
A0A2M4A4P6 A0A2M4A5H4 A0A1Y1M6Q5 A0A1A9WXE3 A0A1W4X5H5 C4XV92 A0A0Q9X8V6 C4XV93 A0A3B0JYT2 T1HPS1 A0A182IUY4 A0A3B0KKB4 A0A1A9Z449

EC Number

4.6.1.2

Pubmed

19121390 22118469 28004739 12554084 19461966 17994087 + More
18057021

EMBL

BABH01034588 ODYU01006444 SOQ48295.1 AGBW02011826 OWR46086.1 GGFK01002437 + More
MBW35758.1 GGFK01002474 MBW35795.1 GGFK01002814 MBW36135.1 GGFK01002442 MBW35763.1 GGFK01002743 MBW36064.1 GEZM01040945 JAV80698.1 BK006720 DAA06504.1 CH933807 KRG03817.1 BK006721 DAA06505.1 OUUW01000010 SPP85592.1 ACPB03001473 SPP85591.1

Proteomes

UP000005204 UP000007151 UP000091820 UP000192223 UP000009192 UP000268350 + More
UP000015103 UP000075880 UP000092445

PRIDE

H9J2R5

Pfam

PF07714 Pkinase_Tyr + More
PF01094 ANF_receptor

Interpro

IPR011009   Kinase-like_dom_sf        + More
IPR001245   Ser-Thr/Tyr_kinase_cat_dom
IPR017441   Protein_kinase_ATP_BS
IPR020635   Tyr_kinase_cat_dom
IPR008266   Tyr_kinase_AS
IPR000719   Prot_kinase_dom
IPR028082   Peripla_BP_I
IPR001828   ANF_lig-bd_rcpt

SUPFAM

SSF56112 SSF56112 + More
SSF53822 SSF53822

ProteinModelPortal

H9J2R5 A0A2H1W5C3 A0A212EX59 A0A2M4A536 A0A2M4A4W5 A0A2M4A5V4 + More
A0A2M4A4P6 A0A2M4A5H4 A0A1Y1M6Q5 A0A1A9WXE3 A0A1W4X5H5 C4XV92 A0A0Q9X8V6 C4XV93 A0A3B0JYT2 T1HPS1 A0A182IUY4 A0A3B0KKB4 A0A1A9Z449

PDB

4UXL E-value=2.33821e-35, Score=376

KEGG

101742154 no KO assigned | (RefSeq) uncharacterized LOC101742154

GO

GO:0005524 GO:0004383 GO:0004713 GO:0016021 GO:0004965 GO:0004672 GO:0006468 GO:0005515 GO:0005488 GO:0006289 GO:0004518 GO:0006281 GO:0048384

Length:

892

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

3.40538

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00830

outside

1 - 892

Pi

5.063282

Theta

5.834498

Tajima's D

-0.371562

CLR

0.998515

CSRT

0.274686265686716

Interpretation

Uncertain

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics