Silkworm Genome Informatics Database

Gene

KWMTBOMO02344

Pre Gene Modal

BGIBMGA003800

Annotation

PREDICTED:_uncharacterized_protein_LOC101741863_[Bombyx_mori]

Location

Bomo_Chr4(+):18586402-18600088 View in EpiBrowser

Full name

Guanylate cyclase

Location in the cell

Cytoplasmic Reliability : 1.037 PlasmaMembrane Reliability : 1.241

CDS

ATGGGCGAGCTTACTCTCCCAGAGCTAGGTCCACCGCCTGGTGCTGTCATTACCGGAGCCATAGACATCGCAAGGTGGTGGCCGAGGGCGCTCTGTCTCTGGAGCGCGCTGAGTTTGCTGGCTGTGATCGCACACACAGACAGTGATGACGTCCCCGAAGTAGTAGTGAGTGCTGTGACGCTGGAGAGAGACGGAGCGGTGCTGGCGGAGGTGGTCCGCGCCGCCCTCAGCCGAGCCGGAGTCCACGCCCGGGTGTCTCCGCCGGCGCCCGTCTGCTCGCGGCCTGACTCCAGCGCCTGCCTATACGCTACGCTGCGAGACCTCGTGCGCGGCTCGGTGACGGCGGCATTGCTGCCCGTGGGCGCGCAGCTCCCGCCCGCGCTGCAGCTGCGAGACGCGGGGCTAGAAGAGCTAGGCGATGCGGCCTCCCCCTCCCGACGCACCTGCCTCTCCTCCCCTCCTGCCCGATCCCTGCTCGACCTCGCCGACGAGGAAATCGCTCGTCTCTACTACGTCGCGCCCGACGTCCTGGGCGAACACAATTATACCAGGGTGTTAACGTTTCCTAATTCAACTTGCAAGATCGGAACTCGTTCCAATGCTAACCAGAGCTGCACTCAAGAAACCGGCTTTGCAACTATTCTCTCAGACGACCCTGACGAAGCGGCGCTGTTGACTGAAGTGGTGGCCCAGTGGGGACTGAGGGCACGAGTGGTAACCAGCAACGCTCACAACACCGCTCTGCCTCCTCCCGCCCTGCGCTGCACCACCACCGCCCTACGCCGTCTCCGTCACTTCACTACCGCCGGCTATAGACCTCTGGCACCGCCGCCTTGCACTGAGACTCACTGTCCCTTCGAGTCACGGCGACTCGTCAAACTCGTCAACGCTCGCCAGCTGACTCGCTCACCCAGCGCTTACAGGATCCTAGGTCGGATCGTTTTTGAGGAACAGGAATTGGTCGAGCTCGCCGAACGATCCCATACGGTCGGGCCTGAGATGGCGGCTCGTGAATTCGTGGAGTCTCGGCCGCGCTGGGCATCGCCCCCGGCCGAGGTGCGCGTCGCCGTGATCGTGCCCGCCACCTCGCCCCGCCAGGTGCAGGACGCGCGTGCCCTGCGAGCCGCCGCCGAGCTCGCGGAGAAGGACATCCTTGAGACCAAGGGAACGCTGCGTTTCAAAGTAGAACTCGTCGATGGCGGATGCGCCGCAACGCCTGCTTTTAAATACCTCACAGACGCGCTGGGCACGGAGTACGGCGCTCTGTCAGCCGTGGCTGGACCGGCGTGCGGGGCCGCATTCGCGGACGTTGCTCGGCAAAGTCCAACGCTGGCCTTGCCGTTGCTCGCGTACACACCACAAGCTCCTCCATCGGACGGGGGGGGGCACCTGGCGCTCCTAACGGGGGGCGACGCGCGGCTCTACACGGACGCCTGGGCGACTCTACTGAATCACTTCGGGTGGCGGCGACTAGCAGTTCTCAGCGAGCTTTCTATGCGACCTGCACTTGAAGTTTCACGTCTGCGCGTCGACAACATATTGGTGCACGTCGAACTCACCACAGACGCAGAAGAAGTGAACTTGGAACTTATCAACGGCTGGGCGGAGCGAGCAGCACGAGAGAACGCGCGCGTGCTGCTGGTGAGTGCAGAGGACGCGCGCGTGGTGCGGGCGGCGCTGACCGCGGGACGGCGCGCCGGGCTCGCGGCCTGCGTGTGGCTGCTGCCCGCGCTGGAGCCGCTCGGGTCGCTCGCCGACGGACATTTCAGCTTCGTCCCAAGCTGGTTCCTCGACTGGAAACCGGACTCTACGACTGAGCGTCGCCGATGGACGTCGCGTTGGAACGAGCTATGTGCGCGGGGCCCGAGGGGTGGCGGCGCGTGCCTCTCTCCACCGGCGACCGCGGCCTTGCTGTACGATGTGCTTCAGCTCTGGGCGGCCGCGTTGCGCCGACTGCTAACCTCGCGCCCGGCCTCCCTCGACGATCTGCACCGCAAAGATATAGTTCAGTTTCTCGTCGAAGACGCAACGAAAGCCAATTACAGTGGACTCACTGGGGTATTCAAGTGGACGACAGCAGATGAGTCGAAAGCCCGCGTCGCGGATTTGTTATTGCTTCAGTGGAACAACGGGACAGCACGTCGCGTAGGGCGCTGGCACGACGGCGTCCTCGTGCTCGACGACGGTGCGATACGGTGGAACACGACAGACGGCCGCGCGCCCGACGACGGCGCCGAGCGATGCGCGCTGCAGCCGCTCGCGGACCTCCTGCGGGCTGACTGTCGCGTGGCTTTCGTGACCGTGGCCACGCTCGCCCTCGCGCTGGCGGTGAGCGCGCTGGCGGCTGGTGCCTGGCTCTGCAAGCGACGCGCCGAGCGGGAATACCGCGCCCGCCTCGCCGAGTTAGGCCTGCGTGCGCTGGTGCCCGAGCCGGGCGGCCTCGACAAGTGGGAAGTTCCCCGCGAACGTGTCGTAATTAACAGGAAGCTTGGAACTGGTGCCTTCGGCATGGTCTACGGAGGTCACGCGCTGCTCGCCGAAGATAGAGGATGGAGCGCGGTTGCCGTAAAAACCTTGAAAGCGGGTGCGACAACGGAAGAAAAACTAGACTTCCTCTCGGAAGCGGAGGCTATGAAACGGTTCGAACATAAGAATGTGGTCCGTCTCCTCGGTGTCGTCACGAAAACGGAACCCGTGTGCACAGTGATGGAATTCATGCTATACGGGGACCTGAAGAACTACTTGTTGGCGCGGCGCCACCTGGCGGGCGCGGGCGGCGCGGCGGCCGAGGAGGTGTCCCCGCAGCGCCTCACTGCGATGGCGCTGGACGTGGCTCGCGCGCTGTCGTACCTGGCGCAGCTGCGCTATGTGCACCGCGACGTCGCCGCCAGGAACTGTCTCATCAGCGCTAACCGCGTCGTGAAGCTGGCAGATTTTGGAATGACTCGACTTGTGTTCGAGAACGACTACTACAGGTTCAGCCGCAAGGGGATGCTGCCGGTGCGCTGGATGGCGCCGGAGAGTCTCGCGCTGGGCGTGTTCTCCCCCGCCTCTGACGTGTGGTCATTCGGCGTTCTGCTCTACGAAATAGTGACTTTCGGCGCGCTGCCGTTCCAAGGGCTCAGCAACTCAGAGGTGCTGGCGCGCGTGAAGGCGGGCCATACGCTCGACCTCCCCGCGGGACTGAAGCCGCAGCTGGAGGGCCTGATGAAGTCGTGCTGGCAGCGAGAGAGGCGCGCCCGGCCCAGCGCGGCCGAGGTCGCCGCCTTCCTCGCGGACTGGGGCCGGCTGCTGACGCCCTGCACCGACGCGCCTCTCGACGCCCTGTCCTTCGACGGCGAGTGGCGCGCGCGGGGCTCGTGGGCCACACCGCTCACCGACACCACCTACCTCAGCGCCGACCTGCCGCGCGATACCGACGCCTTCCTGCCATCCTGA

Protein

MGELTLPELGPPPGAVITGAIDIARWWPRALCLWSALSLLAVIAHTDSDDVPEVVVSAVTLERDGAVLAEVVRAALSRAGVHARVSPPAPVCSRPDSSACLYATLRDLVRGSVTAALLPVGAQLPPALQLRDAGLEELGDAASPSRRTCLSSPPARSLLDLADEEIARLYYVAPDVLGEHNYTRVLTFPNSTCKIGTRSNANQSCTQETGFATILSDDPDEAALLTEVVAQWGLRARVVTSNAHNTALPPPALRCTTTALRRLRHFTTAGYRPLAPPPCTETHCPFESRRLVKLVNARQLTRSPSAYRILGRIVFEEQELVELAERSHTVGPEMAAREFVESRPRWASPPAEVRVAVIVPATSPRQVQDARALRAAAELAEKDILETKGTLRFKVELVDGGCAATPAFKYLTDALGTEYGALSAVAGPACGAAFADVARQSPTLALPLLAYTPQAPPSDGGGHLALLTGGDARLYTDAWATLLNHFGWRRLAVLSELSMRPALEVSRLRVDNILVHVELTTDAEEVNLELINGWAERAARENARVLLVSAEDARVVRAALTAGRRAGLAACVWLLPALEPLGSLADGHFSFVPSWFLDWKPDSTTERRRWTSRWNELCARGPRGGGACLSPPATAALLYDVLQLWAAALRRLLTSRPASLDDLHRKDIVQFLVEDATKANYSGLTGVFKWTTADESKARVADLLLLQWNNGTARRVGRWHDGVLVLDDGAIRWNTTDGRAPDDGAERCALQPLADLLRADCRVAFVTVATLALALAVSALAAGAWLCKRRAEREYRARLAELGLRALVPEPGGLDKWEVPRERVVINRKLGTGAFGMVYGGHALLAEDRGWSAVAVKTLKAGATTEEKLDFLSEAEAMKRFEHKNVVRLLGVVTKTEPVCTVMEFMLYGDLKNYLLARRHLAGAGGAAAEEVSPQRLTAMALDVARALSYLAQLRYVHRDVAARNCLISANRVVKLADFGMTRLVFENDYYRFSRKGMLPVRWMAPESLALGVFSPASDVWSFGVLLYEIVTFGALPFQGLSNSEVLARVKAGHTLDLPAGLKPQLEGLMKSCWQRERRARPSAAEVAAFLADWGRLLTPCTDAPLDALSFDGEWRARGSWATPLTDTTYLSADLPRDTDAFLPS

Catalytic Activity

GTP = 3',5'-cyclic GMP + diphosphate

Similarity

Belongs to the protein kinase superfamily. Tyr protein kinase family.

Feature

chain Guanylate cyclase

Uniprot

A0A212EX70 A0A1E1VYY5 A0A1Y1M6Q5

EC Number

4.6.1.2

Pubmed

22118469 28004739

EMBL

AGBW02011826 OWR46085.1 GDQN01011108 JAT79946.1 GEZM01040945 JAV80698.1 + More

Proteomes

UP000007151

Pfam

PF07714 Pkinase_Tyr + More
PF01094 ANF_receptor

Interpro

IPR000719   Prot_kinase_dom        + More
IPR028082   Peripla_BP_I
IPR020635   Tyr_kinase_cat_dom
IPR008266   Tyr_kinase_AS
IPR017441   Protein_kinase_ATP_BS
IPR011009   Kinase-like_dom_sf
IPR001245   Ser-Thr/Tyr_kinase_cat_dom
IPR001828   ANF_lig-bd_rcpt

SUPFAM

SSF56112 SSF56112 + More
SSF53822 SSF53822

ProteinModelPortal

A0A212EX70 A0A1E1VYY5 A0A1Y1M6Q5

KEGG

101741863 no KO assigned | (RefSeq) uncharacterized LOC101741863

GO

GO:0005524 GO:0004713 GO:0016021 GO:0004383 GO:0006468 GO:0004672 GO:0005515 GO:0005488 GO:0006289 GO:0004518 GO:0006281 GO:0048384

Length:

1145

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

38.43626

Exp number, first 60 AAs:

0.01035

Total prob of N-in:

0.00057

outside

1 - 763

TMhelix

764 - 786

inside

787 - 1145

Pi

21.136421

Theta

4.40967

Tajima's D

0.369927

CLR

0.420053

CSRT

0.498775061246938

Interpretation

Uncertain

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics