Gene

KWMTBOMO02341

Pre Gene Modal

BGIBMGA003755

Annotation

ARRH_HELVI_RecName:_Full%3DArrestin_homolog

Location

Bomo_Chr4(-):18519169-18534041      View in EpiBrowser

Full name

Arrestin homolog       + More
Phosrestin-2      

Alternative Name

Arrestin-1
Arrestin-A
Phosrestin II

Location in the cell

Cytoplasmic   Reliability : 2.313

CDS

ATGGTTTACAATTTCAAAGTGTTCAAGAAGTGCGCGCCCAACGGCAAGCTGACGCTGTACGTCGCCAAGCGGGACTTCGTGGACCACATCACGACGGTGGAGCCGATCGACGGCGTGGTGTTGCTGGACGAGGAGTACGTCCGCGGGCGCAAGGTGTTCGGTCAGGTGGTGTGTACGTTTCGCTACGGGCGCGAGGAGGATGAGGTGATGGGGCTCAACTTCTACAAGGAGCTGTTCCTCGCCTCCGAACAGATCTACCCGCCGCCCGAGAAGCGATCCTATGAACTGACTCGCACGCAGGAGCGACTGATGAAGAAACTGGGAGAGACGGCGCACCCGTTCCACCTGACGGTGCCGGCCGGCGCGCCCGGCTCCGTGACGCTGCAGCCCGGCCTGGAGGACGAGGGCGAGCCTTGCGGGGTGCACTACTACATCAAGCTCTTCGTAGGAGATTCCGAGATAGACAGGTCCCACCGCAGGAGTACAATAGCGCTGGGCATCCGCAAAGTGCAGTACGCGCCTTCGAAGCCCGGCCCGCAGCCCTGCACCGTCGTGCGGAAGGACTTCGTGCTCTCTCCGGGACAACTAGAGCTCGAACTTACTTTGGATAAGCAGCTGTACATGCACGGCGAGACGGTGGCCGTGAACATGAGCGTCCGCAACCACAGCAACAAGGTCGTGAAGAAGATCAAAGCGAACGTGGTCCAGAGCGTCGACGTGGTGCTCTTCCAGAACGGCCAGTACAGGAACGTGGTCGCCAGCATCGAGACCCAGGACGGGTGTCCGCTGCAGCCGGGCTCCAGCCTGCAGAAGGTGCTGCACCTGTCGCCGACGCTGGCCTCCAACAGGGACAAGCGCGGCGTCGCCCTCGACGGACAGCTGAAGCGCGCCGACACCACGCTCGCCTCCACCACTCTGCTGCTGGAGCCGGAGCAGCGTGACGCGTTCGGCATCGTGGTGAGCTACAGCGTGAAGGTGAAGCTGTACCTGGGCGCGCTCAGCGGGGAGCTCGTCGCGGAGCTGCCCTTCATCCTCATGCACCCTAAGGAGGGACGGGCCAAGGTGATCCACGCTGACAGCCAGGCCGACGTGGAGATGTTCCGCCAGGACACCGTGCACCATCAGGAGAGCATCGAGGTCTATTAG

Protein

MVYNFKVFKKCAPNGKLTLYVAKRDFVDHITTVEPIDGVVLLDEEYVRGRKVFGQVVCTFRYGREEDEVMGLNFYKELFLASEQIYPPPEKRSYELTRTQERLMKKLGETAHPFHLTVPAGAPGSVTLQPGLEDEGEPCGVHYYIKLFVGDSEIDRSHRRSTIALGIRKVQYAPSKPGPQPCTVVRKDFVLSPGQLELELTLDKQLYMHGETVAVNMSVRNHSNKVVKKIKANVVQSVDVVLFQNGQYRNVVASIETQDGCPLQPGSSLQKVLHLSPTLASNRDKRGVALDGQLKRADTTLASTTLLLEPEQRDAFGIVVSYSVKVKLYLGALSGELVAELPFILMHPKEGRAKVIHADSQADVEMFRQDTVHHQESIEVY

Description

Regulates photoreceptor cell deactivation. Arr1 and Arr2 proteins are mediators of rhodopsin inactivation and are essential for the termination of the phototransduction cascade.

Similarity

Belongs to the arrestin family.
Belongs to the CD36 family.

Keywords

Sensory transduction   Complete proteome   Phosphoprotein   Reference proteome   Vision  

Feature

chain  Arrestin homolog

Uniprot

A0A2H1V068   H9J2L8   A0A2A4JK76   P55274   A0A194QH06   A0A212EX75   + More
A0A194QU54   A0A2A4JIK8   A2A262   A0A182GJV5   A0A2M4BRT9   W5JMY2   T1DNM3   A0A2M4AEW0   Q16IU7   A0A182K4D8   A0A2M3Z6H3   A0A182WA37   A0A182PVX8   A0A182NNN6   A0A182MCX8   A0A182YIN5   A0A182KJJ5   Q95NF3   A0A182T4H2   A0A182R7N7   A0A182QD30   A0A182WXJ5   A0A182UUL8   A0A182U1X2   U5EZD8   A0A182JN30   F8TBT1   B0W703   F8TBT2   T1E2Q2   A0A1Q3FSG2   J3JTI8   A0A182HQW9   T1D2G3   D6WJ34   A0A336M2N2   A0A1B6DV44   U5EXF4   A0A1B6IUF6   A0A0K8SXB0   A0A0A9Z6A1   A0A1J1IL31   A0A146M606   A0A1B0CD09   A0A1L8DLX0   Q9BIG9   T1HLD8   A0A182FN08   A0A1B0CZF1   A0A1B1QEC1   A0A1D2N788   R4G5A2   A0A0M9AA37   A0A151I0A7   A0A151IUL1   A0A0L7QYP0   A0A154PGX6   A0A1W4XUX2   A0A195FG43   B4I5E2   B3NME0   B4Q8D8   M9NES0   P15372   A0A158N8U6   B4P8N4   B3MMF0   A0A3B0JCB0   E2C1L3   B4KEG0   Q29LC9   B4GQ70   A0A1W4V5R1   B4JCB0   B4LSW4   A0A0C9PR81   B4MYT9   A0A0M3QU80   A0A151ILQ2   A0A088AF54   A0A1W4XKE7   E2A255   A0A2A3EPC6   V9IDF1   A0A0J7NSJ5   A0A232FHS2   K7IUC3   W8BJ48   A0A0K8WK21   A0A034W3M3   A0A310SG72   A0A0A1WT72   A0A1A9YFQ3   A0A1B0APZ4  

Pubmed

19121390    8452755    26354079    22118469    26483478    20920257    + More
23761445    17510324    25244985    20966253    11822731    11792843    12364791    14747013    17210077    24330624    22516182    23537049    18362917    19820115    25401762    26823975    11287006    27289101    17994087    22936249    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    1689056    2105491    12537569    1905538    8316831    21347285    17550304    20798317    15632085    28648823    20075255    24495485    25348373    25830018   

EMBL

ODYU01000071    SOQ34209.1    BABH01034574    NWSH01001297    PCG71802.1    KQ458860    + More
KPJ04792.1    AGBW02011826    OWR46083.1    KQ461191    KPJ07071.1    PCG71801.1    AB291229    BAF45419.1    JXUM01068923    JXUM01068924    JXUM01136320    KQ568411    KQ562525    KXJ69014.1    KXJ75696.1    GGFJ01006357    MBW55498.1    ADMH02000643    ETN65471.1    GAMD01002710    JAA98880.1    GGFK01005966    MBW39287.1    CH478049    EAT34206.1    GGFM01003378    MBW24129.1    AXCM01013525    AY017417    AJ304409    AAAB01008980    AAG54081.1    CAC39103.2    EAA13874.3    AXCN02001996    GANO01000977    JAB58894.1    HQ833831    HQ833832    AEJ33050.1    AEJ33051.1    DS231851    EDS37277.1    HQ833833    AEJ33052.1    GALA01001090    JAA93762.1    GFDL01004511    JAV30534.1    APGK01051400    BT126545    KB741190    KB632094    AEE61509.1    ENN73007.1    ERL88702.1    APCN01001607    GALA01001628    JAA93224.1    KQ971342    EFA04632.1    UFQT01000439    SSX24330.1    GEDC01007783    JAS29515.1    GANO01000975    JAB58896.1    GECU01023146    GECU01017140    JAS84560.1    JAS90566.1    GBRD01008311    JAG57510.1    GBHO01004198    JAG39406.1    CVRI01000055    CRL00949.1    GDHC01004422    JAQ14207.1    AJWK01007292    AJWK01007293    GFDF01006626    JAV07458.1    AJ303080    CAC36938.1    ACPB03006667    AJVK01020714    KX015963    ANT73648.1    LJIJ01000170    ODN01117.1    GAHY01000116    JAA77394.1    KQ435706    KOX80300.1    KQ976616    KYM79262.1    KQ980956    KYN11103.1    KQ414688    KOC63681.1    KQ434902    KZC11109.1    KQ981606    KYN39660.1    CH480822    EDW55598.1    CH954179    EDV54811.1    CM000361    CM002910    EDX05348.1    KMY90764.1    AE014134    AFH03747.1    M30177    M30140    AY061824    ADTU01000133    CM000158    EDW90142.1    CH902620    EDV30896.1    OUUW01000004    SPP79994.1    GL451937    EFN78189.1    CH933807    EDW12928.1    CH379060    EAL34116.1    CH479187    EDW39742.1    CH916368    EDW04143.1    CH940649    EDW64875.1    GBYB01003748    JAG73515.1    CH963913    EDW77278.1    CP012523    ALC40169.1    KQ977104    KYN05820.1    GL435922    EFN72460.1    KZ288199    PBC33615.1    JR039051    JR039052    AEY58505.1    AEY58506.1    LBMM01002008    KMQ95405.1    NNAY01000211    OXU29998.1    AAZX01003847    GAMC01007788    JAB98767.1    GDHF01001104    JAI51210.1    GAKP01010574    JAC48378.1    KQ767877    OAD53255.1    GBXI01012235    JAD02057.1    JXJN01001618   

Proteomes

UP000005204    UP000218220    UP000053268    UP000007151    UP000053240    UP000069940    + More
UP000249989    UP000000673    UP000008820    UP000075881    UP000075920    UP000075885    UP000075884    UP000075883    UP000076408    UP000075882    UP000007062    UP000075901    UP000075900    UP000075886    UP000076407    UP000075903    UP000075902    UP000075880    UP000002320    UP000019118    UP000030742    UP000075840    UP000007266    UP000183832    UP000092461    UP000015103    UP000069272    UP000092462    UP000094527    UP000053105    UP000078540    UP000078492    UP000053825    UP000076502    UP000192223    UP000078541    UP000001292    UP000008711    UP000000304    UP000000803    UP000005205    UP000002282    UP000007801    UP000268350    UP000008237    UP000009192    UP000001819    UP000008744    UP000192221    UP000001070    UP000008792    UP000007798    UP000092553    UP000078542    UP000005203    UP000000311    UP000242457    UP000036403    UP000215335    UP000002358    UP000092443    UP000092460   

PRIDE

H9J2L8    M9NES0    P15372   

Pfam

PF02752   Arrestin_C        + More
PF00339   Arrestin_N
PF01130   CD36
PF02100   ODC_AZ

Interpro

IPR017864   Arrestin_CS        + More
IPR014752   Arrestin_C       
IPR014753   Arrestin_N       
IPR011021   Arrestin-like_N       
IPR000698   Arrestin       
IPR011022   Arrestin_C-like       
IPR014756   Ig_E-set       
IPR002159   CD36_fam       
IPR016181   Acyl_CoA_acyltransferase       
IPR002993   ODC_AZ       
IPR038581   ODC_AZ_sf       

SUPFAM

SSF81296   SSF81296        + More
SSF55729   SSF55729       

Gene 3D

2.60.40.640     2.60.40.840     3.40.630.60    

ProteinModelPortal

A0A2H1V068   H9J2L8   A0A2A4JK76   P55274   A0A194QH06   A0A212EX75   + More
A0A194QU54   A0A2A4JIK8   A2A262   A0A182GJV5   A0A2M4BRT9   W5JMY2   T1DNM3   A0A2M4AEW0   Q16IU7   A0A182K4D8   A0A2M3Z6H3   A0A182WA37   A0A182PVX8   A0A182NNN6   A0A182MCX8   A0A182YIN5   A0A182KJJ5   Q95NF3   A0A182T4H2   A0A182R7N7   A0A182QD30   A0A182WXJ5   A0A182UUL8   A0A182U1X2   U5EZD8   A0A182JN30   F8TBT1   B0W703   F8TBT2   T1E2Q2   A0A1Q3FSG2   J3JTI8   A0A182HQW9   T1D2G3   D6WJ34   A0A336M2N2   A0A1B6DV44   U5EXF4   A0A1B6IUF6   A0A0K8SXB0   A0A0A9Z6A1   A0A1J1IL31   A0A146M606   A0A1B0CD09   A0A1L8DLX0   Q9BIG9   T1HLD8   A0A182FN08   A0A1B0CZF1   A0A1B1QEC1   A0A1D2N788   R4G5A2   A0A0M9AA37   A0A151I0A7   A0A151IUL1   A0A0L7QYP0   A0A154PGX6   A0A1W4XUX2   A0A195FG43   B4I5E2   B3NME0   B4Q8D8   M9NES0   P15372   A0A158N8U6   B4P8N4   B3MMF0   A0A3B0JCB0   E2C1L3   B4KEG0   Q29LC9   B4GQ70   A0A1W4V5R1   B4JCB0   B4LSW4   A0A0C9PR81   B4MYT9   A0A0M3QU80   A0A151ILQ2   A0A088AF54   A0A1W4XKE7   E2A255   A0A2A3EPC6   V9IDF1   A0A0J7NSJ5   A0A232FHS2   K7IUC3   W8BJ48   A0A0K8WK21   A0A034W3M3   A0A310SG72   A0A0A1WT72   A0A1A9YFQ3   A0A1B0APZ4  

PDB

3GC3     E-value=3.70867e-89,     Score=837

KEGG

101739637    K13808 arrestin-1 | (RefSeq) arrestin homolog

GO

GO:0007165   GO:0016021   GO:0005737   GO:0001664   GO:0002031   GO:0008073   GO:0007608   GO:0016028   GO:0045494   GO:0006897   GO:0016060   GO:0002032   GO:0002046   GO:0007601   GO:0016059   GO:0006606   GO:0008565   GO:0005515   GO:0005488   GO:0006289   GO:0004518   GO:0006281   GO:0048384  

PANTHER

PTHR11792   PTHR11923  

Length:

381

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.03659

Exp number, first 60 AAs:

0

Total prob of N-in:

0.02173

outside

1  -  381

 

 

Pi

16.731148

Theta

16.231556

Tajima's D

-1.240821

CLR

2.903334

CSRT

0.0891955402229889

Interpretation

Uncertain