Gene

KWMTBOMO02337

Annotation

endonuclease-reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr4(-):18295923-18299307      View in EpiBrowser

Full name

Integrin beta       + More
Sodium/hydrogen exchanger      

Location in the cell

Mitochondrial   Reliability : 2.092 Nuclear   Reliability : 1.572

CDS

ATGGCAACCCCCCCCAACATGGCTGACACAAATAAAAACTGGCCCCCAGTCCCCGGCAGCTCCGCTATTCCTGGCTACGGTAGCGGTCAAGGTAACGGCGGGGCAGGGGGTGCTAAGAATCTCCGGCAGAGATCCGGCTACCATAAAAAACGACGACTGGACCTGGCAACATACAACGTGCGAACACTGCGGACCGATGAGAAGATTGTGGAACTCGAGGAAGAATTGAGCAGGTTACGGTGGGACATTGTGGGCTTATCTGAAGTCCGAAGAGAGGGAGAGGACACGATAACTCTGAGGTCCGGTAACTTGCTCTATTTTCGAGAAGGTGATCATCTGTCTCAAGGCGGTGTCGGATTTTTCGTCCACAAGTCCCTTGTGAATAATGTGCTCAAAATCGAGAGTGTGTCAACCAGGGTGGCGTACCTTGTACTCAGAATCACCAAAAAGTATTCGTTGAAGATCATACAGGTTTACGCTCCGACCTCGGCACACTCCGACGATGAGGTAGAGACTATGTATGAGGACATTTCCAGAGCCATGCATAGCTTTAAAACTCACATCACCATTGTCATGGGGGATTTCAACGCCAGACTGGGTAAACGGTCCGAGGGGGAGCTGCGAGTGGGACCATTTGGATTTGGGAATCGAAATCATCGGGGAAACCTACTTGCCGGTTTCATGGAGAAAGAAGAATTATTTATGATGAACTCTTTCTTCCAAAAACGGAATCACAGGAAGTGGACCTGGATGAGCCCCAATGGTGCCATCAAAAATGAGATAGATTTCATTATGTCGACAAAAAGGCAAATATTCAATGATGTCTCTGTGATCAATATGGTTAAAACAGGAAGTGATCATCGGATGGTAAGAGGCACATTGAACCTCAATATTAAGCTTGAGAGATTCCGACTGATAAGGTCTACGCTCCGTCCAGCACCAGCTCAGATCCAAAGTTCTGGGCACTTTCAGCTCGAACTTCAAAACCGCTTCGATTGCCTAGGAGGCTCCGTGGACGATTACAATGACGGGTTTGTGAATGCTGTCCATACGATTGGTTCCAAGTTTTTTGGAGCCCGTCGTACAAACAGAACCAAAAAACTCTCAGACCCTACTCTCAAACTCATGGAAGAACGTCGCGGAATGATTTTGCAGTCTTCAGAAGATTCGTTTAAATATCGGTCTCTCAACAGACAGATCTCAAAGTCTCTTAAATTTGATCTACGCCGTTTTAATACTGAGCGTATTAAAGAGGCTATAGAACGAAACAAAGGCTCCAAGGTGTTCGCGAGAGATTTGTCTCTTGGGAAAAGCCAGTTGACAAGACTGAAGATCGATGATGGCAGGATCATTTCGTCCAAGCCTGAGCTTTTGAGAGAGGTCGAGAAGTTCTATGGACAGCTATACACATCTACTCGACAACCCGTGGAATATCTAGCAAAGGATCCAAGAGCTAGATTAGTCCGACACTATACCGAAGATATCCCCGACATCAGCCTGTGCGAGATTAGAATGGCTCTCAAGCAACTTAAGGACAACAAGGCACCGGGCGAGGATGGAATTACCGTCGAACTTCTGAAGGCGGGTGGAAAACCAGTCCTTCGGGCCCTACAAAATTTATTTAATTCCGTCATTCTCGATGGGAATGTGCCCCTGGCATGGACCAGAAGTGTGGTGGTACTGTTCTTCAAAAAGGGTGACAATACTCGTTTGAAGAATTATAGACCCATCTCACTTCTGAGTCATGTCTATAAGTTGTTCTCGAGAGTTATTACGAACCGTCTCGCGCGCAGGTTTGATGACTTCCAGCCACCCGAACAAGCCGGTTTCCGAAAAGGCTATAGTACCGTAGACCACATTCATACGTTGCGGCAGATTGTACAAAAGACCGAGGAATATAACCTGCCGCTTTGCTTAGCATTTGTGGACTACGAGAAAGCCTTTGATTCGATTGAAACCTGGGCCGTGTTACAGTCTCTCCAACGGTGCCAAATTGATTATCGGTATATCGAAGTGTTGAGGTGTTTGTATGAAAACGCTACTATGTCAGTCCGAGTACAGGACCGGGCTTCAGAACCTATCCTTCTGCAGCGGGGCGTGAGGCAAGGAGATGTTATTTCTCCGAAACTATTTACCGCTGCGCTGGAAGATGTTTTCAAAGTTCTGGACTGGAAAGGACTAGGCATCAACATAAACGGCGAGTACATAACTCACCTTCGGTTCGCCGATGATATTGTGATTATGGCCGAGACCATGGAGGACCTCAGTACAATGCTCAAAGACCTCAGTAGGGCTTCTATCCGAGTGGGTCTAAATATGAACAAAGAAAAAACAAAAATTATGTTGAATGCTCATGTAGCGCCCACTCCAGTAAAGATCGGAGGCTCTACGCTCGAAGTTGTTGACGAGTATATTTACCTGGGACACACTGTCCAGCTAGGTAAGTCCAACTTCGAAAAAGAGGTCAACCGTCGAATCCAGCTCGGATGGGCAGCGTTCGGAAAGCTACGTAAAATCTTCTCATCACAAATACCACAGTGTCTCAAGACGAAAGTCTTTGACCAGTGTGTGTTGCCAGTGATGACATATGGCACTGAGACGTGGTCGCTCACAATGGGCCTTATGAGAAGGCTCAAGGTCACCCAAAGAGCAATGGAGAGGGCTATGCTCGGAGTTTCCCTGCGAGACCAAATCAGAAATGAGGAGATTCGCAGGAAAACCATGGTAACCGACATAGCCCAAAGGATTGCGACACTGAAGTGGCAGTGGGCAGGACACATTGCTCGCGGAACAGATGGCCGTTGGGGCCAGAAGGTTCTTGAGTGGCGACCGCGTACTGGGAGACGTAGCGTGGGTAGGCCTCCCACAAGGTGGGCCGACGACCTATTAAGGTTCGCGGGGATCCGCTGGATGCAGGCAGCGCAGGACCGGTCTTTGTGGCAAGGCTTGGGGGAGGCCTATGTCCAGCAGTGGACGTCCATGGGCTGA

Protein

MATPPNMADTNKNWPPVPGSSAIPGYGSGQGNGGAGGAKNLRQRSGYHKKRRLDLATYNVRTLRTDEKIVELEEELSRLRWDIVGLSEVRREGEDTITLRSGNLLYFREGDHLSQGGVGFFVHKSLVNNVLKIESVSTRVAYLVLRITKKYSLKIIQVYAPTSAHSDDEVETMYEDISRAMHSFKTHITIVMGDFNARLGKRSEGELRVGPFGFGNRNHRGNLLAGFMEKEELFMMNSFFQKRNHRKWTWMSPNGAIKNEIDFIMSTKRQIFNDVSVINMVKTGSDHRMVRGTLNLNIKLERFRLIRSTLRPAPAQIQSSGHFQLELQNRFDCLGGSVDDYNDGFVNAVHTIGSKFFGARRTNRTKKLSDPTLKLMEERRGMILQSSEDSFKYRSLNRQISKSLKFDLRRFNTERIKEAIERNKGSKVFARDLSLGKSQLTRLKIDDGRIISSKPELLREVEKFYGQLYTSTRQPVEYLAKDPRARLVRHYTEDIPDISLCEIRMALKQLKDNKAPGEDGITVELLKAGGKPVLRALQNLFNSVILDGNVPLAWTRSVVVLFFKKGDNTRLKNYRPISLLSHVYKLFSRVITNRLARRFDDFQPPEQAGFRKGYSTVDHIHTLRQIVQKTEEYNLPLCLAFVDYEKAFDSIETWAVLQSLQRCQIDYRYIEVLRCLYENATMSVRVQDRASEPILLQRGVRQGDVISPKLFTAALEDVFKVLDWKGLGININGEYITHLRFADDIVIMAETMEDLSTMLKDLSRASIRVGLNMNKEKTKIMLNAHVAPTPVKIGGSTLEVVDEYIYLGHTVQLGKSNFEKEVNRRIQLGWAAFGKLRKIFSSQIPQCLKTKVFDQCVLPVMTYGTETWSLTMGLMRRLKVTQRAMERAMLGVSLRDQIRNEEIRRKTMVTDIAQRIATLKWQWAGHIARGTDGRWGQKVLEWRPRTGRRSVGRPPTRWADDLLRFAGIRWMQAAQDRSLWQGLGEAYVQQWTSMG

Similarity

Belongs to the integrin beta chain family.
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

Feature

chain  Integrin beta

Uniprot

D7F164   D7F158   A0A437BHD1   D7F159   D7F157   D7F165   + More
D7F160   D7F166   A0A437B0R4   A0A2W1BZV1   A0A2H1VS24   A0A023EXV2   A0A0K0FAW8   D7F179   D7F176   A0A016SG46   A0A016TK11   A0A016W4R1   D7F177   A0A023EWU8   A0A2G8JFM9   D7F178   A0A016S1D2   A0A0P4VWD0   A0A0N5C0B1   A0A016V419   E3MH09   E3NC15   A0A016ULU9   A0A016WPY4   A0A016T7J7   A0A016WCB8   K7HDM3   K7HDM2   K7ICT2   A0A069DZM5   K7I2A3   A0A2H1WF27   K7ICT1   A0A2H2JFN0   K7IG35   K7IBZ5   K7IBZ6   K7H0Q9   K7H0R0   A0A2H2J8I4   A0A016RUR3   A0A016S795   A0A016WA79   A0A016S5B2   A0A016RV73   A0A016VVN3   A0A016RRX8   K7I2A2   K7IG36   A0A016SLV8   K7I2A1   E3N0F4   A0A016V6A2   Q9TZX4   K7H0Q8   E3NGJ2   A0A016U3L3   A0A016U352   E3NJQ7   A0A016SVA2   A0A016SW37   A0A016T9D3   A0A016WE57   A0A016T9A5   A0A069DX96   A0A016THC6   A0A016V4Q8   A0A2W5U8K4   A0A016SX67   A0A016SPR9   A0A016UN79   A0A2H2ITH9   A0A2H2JCS8   A0A2H2JKG1   A0A016T4C4   A0A2H2JKX8   A0A016TQJ1   A0A016VT25   A0A016VGA0   A0A016WYN9   A0A016W1X2   A0A016VLP0   A0A016SY13   A0A016U6B7   A0A016U123  

Pubmed

20470440    28756777    25474469    25730766    29023486    27129103    + More
26334808    8603714    9729877   

EMBL

FJ265549    ADI61817.1    FJ265543    ADI61811.1    RSAL01000057    RVE49824.1    + More
FJ265544    ADI61812.1    FJ265542    ADI61810.1    FJ265550    ADI61818.1    FJ265545    ADI61813.1    FJ265551    ADI61819.1    RSAL01000220    RVE44071.1    KZ149907    PZC78256.1    ODYU01004088    SOQ43598.1    GBBI01004876    JAC13836.1    FJ265564    ADI61832.1    FJ265561    ADI61829.1    JARK01001565    EYB89683.1    JARK01001676    JARK01001446    JARK01001433    EYB83199.1    EYC01126.1    EYC02928.1    JARK01001337    EYC34625.1    FJ265562    ADI61830.1    GBBI01004877    JAC13835.1    MRZV01002136    PIK34564.1    FJ265563    ADI61831.1    JARK01001655    EYB84321.1    GDKW01001596    JAI54999.1    JARK01001354    EYC21986.1    DS268444    EFP01729.1    DS268591    EFO92565.1    JARK01001370    EYC16150.1    JARK01000173    EYC41342.1    JARK01001736    JARK01001462    JARK01001379    JARK01001338    EYB80775.1    EYB98943.1    EYC13646.1    EYC33347.1    JARK01000388    EYC37469.1    GBGD01000380    JAC88509.1    ODYU01008249    SOQ51673.1    JARK01001711    EYB81734.1    JARK01001621    EYB86109.1    JARK01000460    EYC36749.1    JARK01001626    EYB85833.1    JARK01001700    JARK01001393    EYB82228.1    EYC10181.1    JARK01001340    EYC30828.1    JARK01001730    EYB81048.1    JARK01001543    EYB91356.1    DS268505    EFP13372.1    JARK01001353    EYC22263.1    AF054983    AAC72298.1    DS268655    EFO97114.1    JARK01001395    EYC09730.1    EYC09729.1    DS268752    EFP01106.1    JARK01001505    EYB94618.1    EYB94617.1    JARK01001459    EYB99276.1    JARK01000343    EYC38099.1    EYB99275.1    GBGD01000453    JAC88436.1    JARK01001438    EYC02111.1    EYC21713.1    QFQQ01000179    PZR20596.1    JARK01001500    JARK01001343    EYB95040.1    EYC28825.1    JARK01001531    EYB92324.1    EYC16376.1    JARK01001475    EYB97550.1    JARK01001421    EYC04912.1    EYC30744.1    JARK01001346    EYC26445.1    JARK01000063    EYC44387.1    EYC33297.1    JARK01001344    EYC28216.1    JARK01001497    EYB95322.1    JARK01001389    EYC10874.1    JARK01001401    EYC08686.1   

Proteomes

UP000283053    UP000035680    UP000024635    UP000230750    UP000046392    UP000008281    + More
UP000005237   

PRIDE

D7F164    D7F158    D7F159    D7F157    D7F165    D7F160    + More
D7F166    D7F179    D7F176    D7F177    D7F178   

Pfam

PF00078   RVT_1        + More
PF14529   Exo_endo_phos_2
PF00362   Integrin_beta
PF13520   AA_permease_2
PF00201   UDPGT
PF03372   Exo_endo_phos
PF00069   Pkinase
PF10328   7TM_GPCR_Srx
PF00999   Na_H_Exchanger

Interpro

IPR000477   RT_dom        + More
IPR036691   Endo/exonu/phosph_ase_sf       
IPR005135   Endo/exonuclease/phosphatase       
IPR032695   Integrin_dom_sf       
IPR036465   vWFA_dom_sf       
IPR015812   Integrin_bsu       
IPR002035   VWF_A       
IPR002369   Integrin_bsu_VWA       
IPR020846   MFS_dom       
IPR002293   AA/rel_permease1       
IPR002213   UDP_glucos_trans       
IPR017441   Protein_kinase_ATP_BS       
IPR008271   Ser/Thr_kinase_AS       
IPR011009   Kinase-like_dom_sf       
IPR000719   Prot_kinase_dom       
IPR001507   ZP_dom       
IPR019430   7TM_GPCR_serpentine_rcpt_Srx       
IPR017452   GPCR_Rhodpsn_7TM       
IPR018422   Cation/H_exchanger_CPA1       
IPR006153   Cation/H_exchanger       
IPR004709   NaH_exchanger       

SUPFAM

SSF56219   SSF56219        + More
SSF53300   SSF53300       
SSF69179   SSF69179       
SSF56112   SSF56112       

Gene 3D

3.60.10.10     3.40.50.410    

CDD

cd06174  MFS

ProteinModelPortal

D7F164   D7F158   A0A437BHD1   D7F159   D7F157   D7F165   + More
D7F160   D7F166   A0A437B0R4   A0A2W1BZV1   A0A2H1VS24   A0A023EXV2   A0A0K0FAW8   D7F179   D7F176   A0A016SG46   A0A016TK11   A0A016W4R1   D7F177   A0A023EWU8   A0A2G8JFM9   D7F178   A0A016S1D2   A0A0P4VWD0   A0A0N5C0B1   A0A016V419   E3MH09   E3NC15   A0A016ULU9   A0A016WPY4   A0A016T7J7   A0A016WCB8   K7HDM3   K7HDM2   K7ICT2   A0A069DZM5   K7I2A3   A0A2H1WF27   K7ICT1   A0A2H2JFN0   K7IG35   K7IBZ5   K7IBZ6   K7H0Q9   K7H0R0   A0A2H2J8I4   A0A016RUR3   A0A016S795   A0A016WA79   A0A016S5B2   A0A016RV73   A0A016VVN3   A0A016RRX8   K7I2A2   K7IG36   A0A016SLV8   K7I2A1   E3N0F4   A0A016V6A2   Q9TZX4   K7H0Q8   E3NGJ2   A0A016U3L3   A0A016U352   E3NJQ7   A0A016SVA2   A0A016SW37   A0A016T9D3   A0A016WE57   A0A016T9A5   A0A069DX96   A0A016THC6   A0A016V4Q8   A0A2W5U8K4   A0A016SX67   A0A016SPR9   A0A016UN79   A0A2H2ITH9   A0A2H2JCS8   A0A2H2JKG1   A0A016T4C4   A0A2H2JKX8   A0A016TQJ1   A0A016VT25   A0A016VGA0   A0A016WYN9   A0A016W1X2   A0A016VLP0   A0A016SY13   A0A016U6B7   A0A016U123  

PDB

6AR3     E-value=2.78436e-06,     Score=126

KEGG

100158253    K02649 phosphoinositide-3-kinase regulatory subunit alpha/beta/delta | (RefSeq) Pi3k60, pi3k; phosph

GO

GO:0003964   GO:0004519   GO:0016758   GO:0004672   GO:0005524   GO:0016021   GO:0006885   GO:0015385  

PANTHER

PTHR10082   PTHR10110  

Subcellular location

Membrane  

Length:

995

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.02371

Exp number, first 60 AAs:

0.00082

Total prob of N-in:

0.00008

outside

1  -  995

 

 

Pi

14.344572

Theta

18.816744

Tajima's D

-0.967766

CLR

40.119689

CSRT

0.138243087845608

Interpretation

Uncertain