Gene

KWMTBOMO02329  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA003758

Annotation

karyopherin_alpha_3_[Bombyx_mori]

Location

Bomo_Chr4(-):17889743-17895821      View in EpiBrowser

Full name

Importin subunit alpha      

Location in the cell

Cytoplasmic   Reliability : 2.19

CDS

ATGGCGACTGATCAAGCGAAAAACCGCATGCATGTGTTCAAGAATGCAGGCAAAGATGTCGATGAAATGCGCAGGCGAAGGAATGAAGTCACAGTCGAGTTAAGAAAAAACAAAAGAGAGGAAACACTTCAGAAACGGCGTAATGTGCCCATTAGCTATTCTACCGATGAGGAGGAGATCGACAAGAACCTCGCTACCACCGACCTTGATGAGCTGGTGATGAACGCTGCCAACGCAGAAAACCCTGAAGCACAGTTGGCTGCTGTGCAACAATGCAGAAAACTGCTCTCGTGTGATAAAAACCCGCCTATTGATGAGCTCATAGCTGCTGGAATACTCCCCATCCTAGTTCAGTGCCTTTCGAGGGCTGACAATCCAGCGTTACAATTCGAGACCGCTTGGGCTTTAACAAACATAGCTTCCGGAACGTCTGCACAAACAAACAAAGTAGTCCATGCCGGTGCAGTACCTGTATTCCTTCAGCTCTTGATGTCACCTCATGAAAACGTATGTGATCAGGCAGTATGGGCCCTCGGTAACATAATCGGCGACGGTCCAGTCCTTCGAGACTTTGTGATAGAACTAGGAGTTGTCAAACCACTACTGAGCTTAATCAAATCAGACATACCAATCCCATTCCTCAGGAATGTAACATGGGTGATTGTCAACCTCTGCAGGAGTAAAGATCCACCACCACCTCTGAAAACCATCCAGGAGATACTGCCTGCCTTAAATGTTCTAATCCTACACAACGACAGTAGTGTTCTTGTTGATACTGTTTGGGCCATTAGTTATCTAACAGATGGGGGCAATGAACAAATCCAAATGGTGATAGAATCTGGTATAGTAACAACCTTGATTCCGTTGTTGTCGCACAAGGAAGTGAAAGTACAGACGGCCGCCCTAAGAGCAGTTGGTAACATTGTCACAGGAACAGACGAACAAACTCAAGTTGTCCTGAACTGCGATGCTCTCTCACACTTCCCGGCTTTACTGACTCATCCGAAAGAGAAGATATGCAAAGAGGCGGTATGGTTTCTGTCAAACATCACGGCAGGTAATAAACAACAAGTTCAGGCTGTTATTGATGCTGGTCTCCTGCCCATGATTGTGGCCAACCTTAGCAAAGGAGAGTTTCAAACCCAGAAGGAAGCTGCTTGGGCCGTTTCCAACCTCAGCATCAGTGGCACGAGGGACCAAGTTGCTGCACTTATCAATTGTGGAGTTATACCGCCATTCTGTAATCTACTCAGTTGCAAGGATACCCAAGTTATTAATGTTGTACTAGATGGTCTCAGTAACATGCTGAAGATGGCTGGTGACAATGCCGAACAAGTTGCTAACATGATTGAGGAGTGTGGTGGTATTGACAAGATTGAAGATTTGCAGACCCATGAGAAGATGGAAATTTACAAGATGGCTTATGATATCATAGAACAGTACTTTGCGGGAGAGGAGGAGGACGCGTCGCTGGTGCCGGCGGCGGGCGAGGCGGCCTTCCAGTTCGACGGCGGCGCCGCCGACAAGGAGCCGCCGCCCTTCCGCTTCTAG

Protein

MATDQAKNRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATTDLDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQEILPALNVLILHNDSSVLVDTVWAISYLTDGGNEQIQMVIESGIVTTLIPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHEKMEIYKMAYDIIEQYFAGEEEDASLVPAAGEAAFQFDGGAADKEPPPFRF

Similarity

Belongs to the importin alpha family.

Uniprot

H9J2M1   Q1HQC3   A0A2A4K2S6   A0A2H1V517   A0A1E1WNU9   A0A2A4K2F0   + More
A0A212EH23   S4P9A4   A0A194QU57   A0A1Y1LM60   A0A0L7LEH9   A0A1B6HPX8   V5I807   D6WM34   A0A1S3D5E1   A0A067QMY2   E2BLZ6   N6TUQ3   A0A158P3J6   A0A1B6DZ56   E9IEA8   A0A1W4XVS2   A0A2J7RBM0   T1IBW3   F4WAS8   A0A224XLY9   A0A026WUD0   A0A0T6B2J8   A0A023F496   E1ZX68   A0A232ENH0   A0A0A9WQY7   A0A0K8SGT0   A0A195F143   K7J8X3   Q16PF9   A0A195BYY1   A0A151XDT6   A0A023ETI5   A0A151IEF8   A0A1X8VIL6   A0A0K8TTF4   U5EZA0   A0A1Q3F497   B0W2E5   A0A0C9RV98   A0A2A3EHU2   V9ILC4   A0A088ANJ0   W8BFE6   A0A0P4X1W6   A0A1L8DVS7   A0A0K8WEE2   A0A2P8ZE70   A0A034WNF6   A0A224YXC7   T1IVG4   A0A131YW83   A0A2M3Z0K2   A0A2M4BL16   T1PAE5   A0A1I8PJY3   A0A0A1XJB6   A0A182NQP2   A0A2M4A3L8   W5JAA4   A0A182IUT1   A0A182PRR2   A0A182RA41   A0A1B6GRU2   A0A182VVW4   A0A182UVY4   A0A182X9H8   Q7PUE1   A0A182HKG1   A0A1A9WJM2   A0A182K158   B3NZP6   A0A084W0M0   A0A182M6U8   B3M2G7   A0A1A9YK62   A0A1A9UNA6   A0A182Q616   A0A1B0BBZ4   D3TLH3   A0A3B0JNQ6   Q295I8   B4GDT3   B4PUR3   A0A154NY60   B4NKL7   A0A182YBH1   A0A1J1HSR2   E9HA62   A0A0P5VV89   A0A164PZF8   A0A0P6BF61   A0A0P5VWK2   A0A1W4VMM4  

Pubmed

19121390    22118469    23622113    26354079    28004739    26227816    + More
18362917    19820115    24845553    20798317    23537049    21347285    21282665    21719571    24508170    30249741    25474469    28648823    25401762    26823975    20075255    17510324    24945155    26369729    24495485    29403074    25348373    28797301    26830274    25315136    25830018    20920257    23761445    12364791    14747013    17210077    17994087    24438588    20353571    15632085    17550304    25244985    21292972   

EMBL

BABH01034508    DQ443129    ABF51218.1    NWSH01000225    PCG78228.1    ODYU01000710    + More
SOQ35931.1    GDQN01002389    JAT88665.1    PCG78229.1    AGBW02014991    OWR40774.1    GAIX01005591    JAA86969.1    KQ461191    KPJ07076.1    GEZM01051730    GEZM01051729    JAV74729.1    JTDY01001539    KOB73606.1    GECU01037005    GECU01033196    GECU01033035    GECU01030959    GECU01027866    GECU01006935    GECU01000194    JAS70701.1    JAS74510.1    JAS74671.1    JAS76747.1    JAS79840.1    JAT00772.1    JAT07513.1    GALX01005515    JAB62951.1    KQ971343    EFA04216.2    KK853149    KDR10659.1    GL449088    EFN83282.1    APGK01051399    KB741190    KB632094    ENN73005.1    ERL88700.1    ADTU01008163    GEDC01006326    JAS30972.1    GL762576    EFZ21075.1    NEVH01005892    PNF38237.1    ACPB03011333    GL888053    EGI68684.1    GFTR01006814    JAW09612.1    KK107109    QOIP01000008    EZA59271.1    RLU19930.1    LJIG01016191    KRT81342.1    GBBI01002386    JAC16326.1    GL435030    EFN74158.1    NNAY01003150    OXU19905.1    GBHO01033763    GDHC01008065    JAG09841.1    JAQ10564.1    GBRD01013477    JAG52349.1    KQ981880    KYN33892.1    CH477784    EAT36241.1    KQ976394    KYM93131.1    KQ982268    KYQ58480.1    GAPW01000975    JAC12623.1    KQ977866    KYM99244.1    KX058565    ARE72528.1    GDAI01000388    JAI17215.1    GANO01001169    JAB58702.1    GFDL01012649    JAV22396.1    DS231826    EDS28691.1    GBYB01011626    GBYB01011627    JAG81393.1    JAG81394.1    KZ288254    PBC30769.1    JR053450    AEY61933.1    GAMC01014594    GAMC01014593    JAB91961.1    GDRN01023792    JAI67762.1    GFDF01003571    JAV10513.1    GDHF01022912    GDHF01002905    GDHF01001298    JAI29402.1    JAI49409.1    JAI51016.1    PYGN01000083    PSN54795.1    GAKP01003657    GAKP01003656    GAKP01003655    GAKP01003654    JAC55298.1    GFPF01009233    MAA20379.1    JH431584    GEDV01005735    JAP82822.1    GGFM01001308    MBW22059.1    GGFJ01004347    MBW53488.1    KA645707    AFP60336.1    GBXI01003307    JAD10985.1    GGFK01002082    MBW35403.1    ADMH02002066    ETN59709.1    GECZ01004640    JAS65129.1    AAAB01008987    EAA01688.5    APCN01000828    CH954181    EDV49756.1    ATLV01019123    KE525262    KFB43764.1    AXCM01000480    CH902617    EDV43420.1    AXCN02001509    JXJN01011738    CCAG010013872    EZ422275    ADD18551.1    OUUW01000008    SPP83874.1    CM000070    EAL28723.1    CH479182    EDW34594.1    CM000160    EDW96680.1    KQ434782    KZC04521.1    CH964272    EDW85189.1    CVRI01000013    CRK89510.1    GL732610    EFX71376.1    GDIP01095401    JAM08314.1    LRGB01002496    KZS07291.1    GDIP01030208    JAM73507.1    GDIP01094140    JAM09575.1   

Proteomes

UP000005204    UP000218220    UP000007151    UP000053240    UP000037510    UP000007266    + More
UP000079169    UP000027135    UP000008237    UP000019118    UP000030742    UP000005205    UP000192223    UP000235965    UP000015103    UP000007755    UP000053097    UP000279307    UP000000311    UP000215335    UP000078541    UP000002358    UP000008820    UP000078540    UP000075809    UP000078542    UP000002320    UP000242457    UP000005203    UP000245037    UP000095301    UP000095300    UP000075884    UP000000673    UP000075880    UP000075885    UP000075900    UP000075920    UP000075903    UP000076407    UP000007062    UP000075840    UP000091820    UP000075881    UP000008711    UP000030765    UP000075883    UP000007801    UP000092443    UP000078200    UP000075886    UP000092460    UP000092444    UP000268350    UP000001819    UP000008744    UP000002282    UP000076502    UP000007798    UP000076408    UP000183832    UP000000305    UP000076858    UP000192221   

PRIDE

H9J2M1    Q1HQC3   

Pfam

PF01749   IBB        + More
PF00514   Arm
PF16186   Arm_3
PF00569   ZZ
PF05605   zf-Di19

Interpro

IPR024931   Importing_su_alpha        + More
IPR016024   ARM-type_fold       
IPR032413   Arm_3       
IPR011989   ARM-like       
IPR002652   Importin-a_IBB       
IPR036975   Importin-a_IBB_sf       
IPR000225   Armadillo       
IPR000433   Znf_ZZ       
IPR008598   Di19_Zn_binding_dom       

SUPFAM

SSF48371   SSF48371       

Gene 3D

1.20.5.690     1.25.10.10    

ProteinModelPortal

H9J2M1   Q1HQC3   A0A2A4K2S6   A0A2H1V517   A0A1E1WNU9   A0A2A4K2F0   + More
A0A212EH23   S4P9A4   A0A194QU57   A0A1Y1LM60   A0A0L7LEH9   A0A1B6HPX8   V5I807   D6WM34   A0A1S3D5E1   A0A067QMY2   E2BLZ6   N6TUQ3   A0A158P3J6   A0A1B6DZ56   E9IEA8   A0A1W4XVS2   A0A2J7RBM0   T1IBW3   F4WAS8   A0A224XLY9   A0A026WUD0   A0A0T6B2J8   A0A023F496   E1ZX68   A0A232ENH0   A0A0A9WQY7   A0A0K8SGT0   A0A195F143   K7J8X3   Q16PF9   A0A195BYY1   A0A151XDT6   A0A023ETI5   A0A151IEF8   A0A1X8VIL6   A0A0K8TTF4   U5EZA0   A0A1Q3F497   B0W2E5   A0A0C9RV98   A0A2A3EHU2   V9ILC4   A0A088ANJ0   W8BFE6   A0A0P4X1W6   A0A1L8DVS7   A0A0K8WEE2   A0A2P8ZE70   A0A034WNF6   A0A224YXC7   T1IVG4   A0A131YW83   A0A2M3Z0K2   A0A2M4BL16   T1PAE5   A0A1I8PJY3   A0A0A1XJB6   A0A182NQP2   A0A2M4A3L8   W5JAA4   A0A182IUT1   A0A182PRR2   A0A182RA41   A0A1B6GRU2   A0A182VVW4   A0A182UVY4   A0A182X9H8   Q7PUE1   A0A182HKG1   A0A1A9WJM2   A0A182K158   B3NZP6   A0A084W0M0   A0A182M6U8   B3M2G7   A0A1A9YK62   A0A1A9UNA6   A0A182Q616   A0A1B0BBZ4   D3TLH3   A0A3B0JNQ6   Q295I8   B4GDT3   B4PUR3   A0A154NY60   B4NKL7   A0A182YBH1   A0A1J1HSR2   E9HA62   A0A0P5VV89   A0A164PZF8   A0A0P6BF61   A0A0P5VWK2   A0A1W4VMM4  

PDB

5TBK     E-value=0,     Score=1783

KEGG

732872    no KO assigned | (RefSeq) karyopherin alpha 3

GO

GO:0008565   GO:0005634   GO:0006606   GO:0005737   GO:0061608   GO:0005112   GO:0009411   GO:0017022   GO:0008270   GO:0016021   GO:0005515   GO:0005488   GO:0006289   GO:0004518   GO:0006281   GO:0048384   GO:0140142  

Length:

516

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.03127

Exp number, first 60 AAs:

0

Total prob of N-in:

0.01574

outside

1  -  516

 

 

Pi

26.612989

Theta

18.040336

Tajima's D

-0.665401

CLR

3.040705

CSRT

0.2036398180091

Interpretation

Uncertain