Gene

KWMTBOMO02295

Pre Gene Modal

BGIBMGA003777

Annotation

PREDICTED:_cyclin_3_isoform_X2_[Bombyx_mori]

Location

Bomo_Chr4(+):17120931-17126314      View in EpiBrowser

Full name

G2/mitotic-specific cyclin-B3      

Location in the cell

Mitochondrial   Reliability : 2.651

CDS

ATGGCGCCAACAAGATTGGCAACGAAACCGCTCGGCGTCAACGAGAACCTGAACGGCATGTTAAGCCACGGCATTACGACGAGGAGTAAACAGCTAGCTTCTCTAAAGAGTCACAAGGACAGTCTAAAAATTCCCAATAAAAGGAAAGCGGACAGTCCTCTTAAAGATGTGACTGCGAAGAGGGCGGCGTTCGGAGATATAACGAACGCCTATAACAAATCGTGCGCGCCCCAGGACAAGGATAAAGCCATGCCAGTGAAGAAAGTCACTGTTGAGACCAAAATGCTTCCAGCAGTAAAGAGCATCAAATCACAAACAAGCACACTAAATGGCAAAACTTCAAAGACCAAACAACTCCAGCGGGTAGCCAATAATGCTATTGATGCAGTACAGAAACATTTCACCAAAGACCCACCCAAGCAAGTGGCCACAAGAGCTCAGAATGGCATCCTGAAGAATTTTGAAAGGAAAGACAAACTCAAAGAGCAGAATCTGAGTAATGGTTCAGTCAAATCTGCAAGAAGTGATGTTTCCGGTGAACCCTCACTTTATATGACTGCCTTGGAGAATATCCCATCTGAGGTAACTAAAGAAGAGTACAAACAAATCAGTGAGAAACTGAACAAAGTAAACTTGGATGACACATCTAGGTCTTTGGATGAAGAAACAGAGACCCCTCATAAAACTCCTTCTGGTGTTCTTGACTTTGACTTTGAGAATTGGAATGATCCACTCCAAGTATCTCATTATGCTATGGACATATTTAATTATTTGAAAAACAGGGAGCGCCTTTTCCCTATTGACGATTACCTGAAACGTATGAATGGAATTACATCGTGGATGAGAGCGCTACTTGTAGACTGGATGGTTGAAGTTCAAGAGAGTTTTGAACTCAATCATGAGACCCTGTATTTGGCTGTGAAGCTAGTTGACTTGTTCCTTACTCGTTCAACTAAGAATGAACAAATAGAACAACTGACAAAGGAGGAATTGCAACTATTAGGAGCATCTGCCTTGTTTATAGCTTCTAAGTTTGATGAGCGCATTCCGCCCCTAGTGGACGACTTCCTGTACATCTGCGACGGGGCATATACGCTGAGCCAACTGCTTAAAATGGAGATGACTATTCTCCGGGTCATCGACTTCGATCTCGGCGTGCCGCTCTCCTACCGGTTCCTCAGGAGATACGCCCGGTGTGCTCGTGTATCAATGCCTACACTAACACTGGCTCGGTTTGTGTTAGAACAATGCTTGTTGGAATATGGACTTATTGAAAATTCAGACAGTAAAATGGCTGCTGCTGCACTGTACCTTGCTCTCAGGATGAAGAATCTAGGTTCATGGACACCCACTCTACAGTATTATACAGGTTACAACCTCAAAGAAATTCTCCCGATTGCATTAGCCCAGAATGCAGTTCTACACAAGAAGCCAAAGTCTGCGATTAGCACAGTTAGGAATAAATACTCACATACAATATTTTTCGAAGTTGCCAAAGTACCCCTAATAGACGAGGCGACGCTCACTAGCTGA

Protein

MAPTRLATKPLGVNENLNGMLSHGITTRSKQLASLKSHKDSLKIPNKRKADSPLKDVTAKRAAFGDITNAYNKSCAPQDKDKAMPVKKVTVETKMLPAVKSIKSQTSTLNGKTSKTKQLQRVANNAIDAVQKHFTKDPPKQVATRAQNGILKNFERKDKLKEQNLSNGSVKSARSDVSGEPSLYMTALENIPSEVTKEEYKQISEKLNKVNLDDTSRSLDEETETPHKTPSGVLDFDFENWNDPLQVSHYAMDIFNYLKNRERLFPIDDYLKRMNGITSWMRALLVDWMVEVQESFELNHETLYLAVKLVDLFLTRSTKNEQIEQLTKEELQLLGASALFIASKFDERIPPLVDDFLYICDGAYTLSQLLKMEMTILRVIDFDLGVPLSYRFLRRYARCARVSMPTLTLARFVLEQCLLEYGLIENSDSKMAAAALYLALRMKNLGSWTPTLQYYTGYNLKEILPIALAQNAVLHKKPKSAISTVRNKYSHTIFFEVAKVPLIDEATLTS

Description

Cyclins are positive regulatory subunits of the cyclin-dependent kinases (CDKs), and thereby play an essential role in the control of the cell cycle, notably via their destruction during cell division. Probably functions redundantly with other cyclins in regulation of cell cycle. Its presence may be required to delay a deadline for completing cytokinesis that is ordinary imposed by nuclear envelope reformation. Degradation of CycB and CycB3 promote cytokinesis furrow initiation and ingression. Required with CycB for female fertility.

Subunit

Interacts with Cdk1 kinase.

Similarity

Belongs to the cyclin family.
Belongs to the cyclin family. Cyclin AB subfamily.

Keywords

Cell cycle   Cell division   Complete proteome   Cyclin   Mitosis   Nucleus   Phosphoprotein   Reference proteome   Ubl conjugation  

Feature

chain  G2/mitotic-specific cyclin-B3

Uniprot

H9J2P0   A8HI21   A0A2A4K8E2   A0A2H1W667   S4P8S9   A0A194QH62   + More
A0A212EML7   A0A0L7LJJ6   A0A194QQ62   K7J596   A0A291S6V0   A0A232FGF7   A0A154PNJ3   A0A0M9A5V3   A0A1W4WNA3   A0A0L7QNT0   A0A088A1H8   A0A2A3EJA1   A0A2J7R661   E2C2R2   A0A067QUB1   A0A195CE28   A0A195BKA8   A0A0J7KUF7   D6WNC8   F4X2P3   E9J286   A0A1Y1L7J4   A0A151WNA0   A0A195DSL3   A0A1A9WYR9   A0A1A9UVG4   E0VTL6   A0A0K8UTM8   Q29CG1   E1ZXN0   A0A034VGF1   B3LV01   B4LWX7   A0A0A1WNS0   A0A0B4KHT9   Q9I7I0   A0A1I8PBZ4   B0X498   B4QTU7   A0A3B0JHH9   A0A336MP55   B4PV23   B4GN38   B4K8C3   B3P6W4   A0A1W4W2G5   B4NG21   A0A0M3QYL5   A0A1Q3EWM2   A0A1Q3EWM8   A0A1B0CAS6   A0A1L8DWW8   W8CDF8   A0A1J1IIC6   B4HHM7   A0A1S4FMV3   Q16VG6   A0A0P4WP59   A0A0P4WGL0   A0A1B6G928   A0A2P2I6B5   N6U2D3   A0A023EZ14   A0A1S3DRG2  

Pubmed

19121390    23622113    26354079    22118469    26227816    20075255    + More
28992199    28648823    20798317    24845553    18362917    19820115    21719571    21282665    28004739    20566863    15632085    17994087    25348373    25830018    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    9851980    7588612    11369230    12620185    18327897    17550304    24495485    17510324    23537049    25474469   

EMBL

BABH01034420    EU074796    ABV66133.1    NWSH01000050    PCG80198.1    ODYU01006605    + More
SOQ48595.1    GAIX01004059    JAA88501.1    KQ458860    KPJ04754.1    AGBW02013812    OWR42716.1    JTDY01000890    KOB75539.1    KQ461191    KPJ07105.1    AAZX01000332    MF432988    ATL75339.1    NNAY01000239    OXU29782.1    KQ434978    KZC13034.1    KQ435748    KOX76479.1    KQ414851    KOC60224.1    KZ288241    PBC31269.1    NEVH01006980    PNF36324.1    GL452203    EFN77747.1    KK853004    KDR12607.1    KQ977957    KYM98486.1    KQ976450    KYM85705.1    LBMM01003109    KMQ93953.1    KQ971343    EFA03235.1    GL888591    EGI59239.1    GL767834    EFZ13064.1    GEZM01066382    JAV67915.1    KQ982919    KYQ49271.1    KQ980489    KYN15838.1    DS235767    EEB16691.1    GDHF01022451    JAI29863.1    CM000070    EAL26685.1    GL435067    EFN74068.1    GAKP01016566    JAC42386.1    CH902617    EDV42473.1    CH940650    EDW67724.1    GBXI01013800    JAD00492.1    AE014297    AGB96314.1    AJ006772    AJ012568    BT003185    DS232333    EDS40251.1    CM000364    EDX14301.1    OUUW01000005    SPP80163.1    UFQT01001658    SSX31331.1    CM000160    EDW98872.1    CH479186    EDW39164.1    CH933806    EDW16505.1    CH954182    EDV53784.1    CH964251    EDW83238.1    CP012526    ALC47829.1    GFDL01015328    JAV19717.1    GFDL01015326    JAV19719.1    AJWK01004228    GFDF01003168    JAV10916.1    GAMC01002021    JAC04535.1    CVRI01000054    CRK99997.1    CH480815    EDW43569.1    CH477593    EAT38552.1    GDRN01055273    JAI65998.1    GDRN01055272    JAI65999.1    GECZ01010850    JAS58919.1    IACF01003962    LAB69565.1    APGK01044620    KB741028    ENN74781.1    GBBI01004267    JAC14445.1   

Proteomes

UP000005204    UP000218220    UP000053268    UP000007151    UP000037510    UP000053240    + More
UP000002358    UP000215335    UP000076502    UP000053105    UP000192223    UP000053825    UP000005203    UP000242457    UP000235965    UP000008237    UP000027135    UP000078542    UP000078540    UP000036403    UP000007266    UP000007755    UP000075809    UP000078492    UP000091820    UP000078200    UP000009046    UP000001819    UP000000311    UP000007801    UP000008792    UP000000803    UP000095300    UP000002320    UP000000304    UP000268350    UP000002282    UP000008744    UP000009192    UP000008711    UP000192221    UP000007798    UP000092553    UP000092461    UP000183832    UP000001292    UP000008820    UP000019118    UP000079169   

PRIDE

H9J2P0    A8HI21    Q9I7I0   

Pfam

PF02984   Cyclin_C        + More
PF00134   Cyclin_N

Interpro

IPR015452   Cyclin_B3        + More
IPR036915   Cyclin-like_sf       
IPR013763   Cyclin-like       
IPR039361   Cyclin       
IPR006671   Cyclin_N       
IPR004367   Cyclin_C-dom       

SUPFAM

SSF47954   SSF47954       

CDD

cd00043  CYCLIN

ProteinModelPortal

H9J2P0   A8HI21   A0A2A4K8E2   A0A2H1W667   S4P8S9   A0A194QH62   + More
A0A212EML7   A0A0L7LJJ6   A0A194QQ62   K7J596   A0A291S6V0   A0A232FGF7   A0A154PNJ3   A0A0M9A5V3   A0A1W4WNA3   A0A0L7QNT0   A0A088A1H8   A0A2A3EJA1   A0A2J7R661   E2C2R2   A0A067QUB1   A0A195CE28   A0A195BKA8   A0A0J7KUF7   D6WNC8   F4X2P3   E9J286   A0A1Y1L7J4   A0A151WNA0   A0A195DSL3   A0A1A9WYR9   A0A1A9UVG4   E0VTL6   A0A0K8UTM8   Q29CG1   E1ZXN0   A0A034VGF1   B3LV01   B4LWX7   A0A0A1WNS0   A0A0B4KHT9   Q9I7I0   A0A1I8PBZ4   B0X498   B4QTU7   A0A3B0JHH9   A0A336MP55   B4PV23   B4GN38   B4K8C3   B3P6W4   A0A1W4W2G5   B4NG21   A0A0M3QYL5   A0A1Q3EWM2   A0A1Q3EWM8   A0A1B0CAS6   A0A1L8DWW8   W8CDF8   A0A1J1IIC6   B4HHM7   A0A1S4FMV3   Q16VG6   A0A0P4WP59   A0A0P4WGL0   A0A1B6G928   A0A2P2I6B5   N6U2D3   A0A023EZ14   A0A1S3DRG2  

PDB

6GU4     E-value=1.94837e-41,     Score=426

KEGG

100126204    K21771 G2/mitotic-specific cyclin-B3 | (RefSeq) cyclin 3

PATHWAY

04068    FoxO signaling pathway - Bombyx mori (domestic silkworm)

GO

GO:0010389   GO:0005634   GO:0019901   GO:0000079   GO:0044772   GO:0016538   GO:0000307   GO:0006468   GO:0005737   GO:0005813   GO:0000281   GO:0035561   GO:0035186   GO:0000278   GO:0005777   GO:0007031   GO:0003676   GO:0008017   GO:0006289   GO:0004518   GO:0006281   GO:0048384  

PANTHER

PTHR10177:SF214   PTHR10177  

Subcellular location

Nucleus  

Length:

510

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.08833

Exp number, first 60 AAs:

0.00015

Total prob of N-in:

0.00241

outside

1  -  510

 

 

Pi

318.438694

Theta

216.498144

Tajima's D

1.263953

CLR

0

CSRT

0.733863306834658

Interpretation

Uncertain