Gene

KWMTBOMO02248

Pre Gene Modal

BGIBMGA003104

Annotation

Chymotrypsin-1_[Operophtera_brumata]

Location

Bomo_Chr4(-):14710878-14711951      View in EpiBrowser

Full name

Chymotrypsin       + More
Trypsin      

Location in the cell

Mitochondrial   Reliability : 1.194

CDS

ATGTCTGGTTTTATTGTGGGCGGATATTTGGCGTCAATCAAGGAATATCCCCACTCAGCTTTTTTGAGAGCCGGTTGCGTCACACCAACCGGTAATGTCCGCAAATGGCAATGTGGATCATCGATAATCAATCAGATGATGTTGCTGACCGCGGCTCATTGCTTAGAAGAGGCAAAGGAAATTCTCGTTACTGTCGGAAGTGAAAACAAAAATATGGGTTTGACAATAAAAGCTGGAAGATACATTATACATGAAAATTATGATCCGTCGGCGTTACATTCGGATCTAGGTCTCATTGGGCTATCTAAGCCGTTGAAATTCACTTCGAAAATACAACGAGTAGCCCTGATGAGGAGCCCGCCTTATAAAGAAAAAGCATTTGTCGCTGGTTGGGGAGTGGTTGACGAAATCAATATCAGAGTGATTCCTGTGTTAAAATATTTGGATCAAATTGTCCGAAATCAGAATAGCTGCTACAAAGAAAAAATCTATGAAGCAATACCAGGAACCATTTGCGCTAGCAATGCAAAAGCCTCAGAATATCCATCTATGTAA

Protein

MSGFIVGGYLASIKEYPHSAFLRAGCVTPTGNVRKWQCGSSIINQMMLLTAAHCLEEAKEILVTVGSENKNMGLTIKAGRYIIHENYDPSALHSDLGLIGLSKPLKFTSKIQRVALMRSPPYKEKAFVAGWGVVDEINIRVIPVLKYLDQIVRNQNSCYKEKIYEAIPGTICASNAKASEYPSM

Description

Serine protease with chymotryptic and collagenolytic activities.

Catalytic Activity

Preferential cleavage: Tyr-|-Xaa, Trp-|-Xaa, Phe-|-Xaa, Leu-|-Xaa.
Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.

Similarity

Belongs to the peptidase S1 family.

Keywords

Collagen degradation   Digestion   Disulfide bond   Glycoprotein   Hydrolase   Protease   Secreted   Serine protease   Signal   Zymogen   Direct protein sequencing  

Feature

propeptide  Activation peptide
chain  Chymotrypsin

Uniprot

H9J0R7   A0A2H1WKW7   A0A2H1VR93   A0A2W1BJQ7   A0A0L7LFE7   A0A0L7KT34   + More
A0A2A4JL27   A0A0L7LF03   A0A212FKP7   A0A194RKI2   H9J0R6   A0A2H1VHC8   A0A194QDC4   A0A0L7LG02   A0A0L7KVC9   A0A0L7LF91   A0A2H1V9I9   A0A194Q913   A0A212FKM8   A0A2H1W4Q5   A0A1A9WKQ0   A0A0L0BSQ2   A0A1B0B1H8   D6WPA6   A0A1A9XWP6   A0A336MUY7   A0A336MXC4   A0A182PK66   T1H2V5   O97398   A0A2D9XLI4   B4JVV3   E0W3U6   A0A1I8M656   A0A1A9Z6S9   Q6XHL5   A1XG66   B5APZ4   B5AQM2   A0A2P2I159   A0A0L0C9D3   A0A182QJV9   B4PJL5   A1XG65   A0NG43   B4J3I4   A0A182KJU0   A0A182IGM8   F1DQG5   D6WZJ8   A0A182IN32   B4KZJ9   O15944   A0A2A3E9B5   A0A182UJ75   A0A2P2I1H3   E1ZZV4   T1GX22   T1GQB9   Q8T4A8   B4HKU3   A0A0A1WN98   D3TMZ8   A0A3G5BIF4   Q28Y22   A7UNZ4   A0A1I8M4V1   A0A084W5I8   A0A1I8M4V2   Q16ZF3   Q25081   T1P9U9   A0A182RAB0   B4JBA6   E9GE64   A7DYX5   A0A3G5BIH9   B4GGG2   P51588   A0A1B0FLW7   B3M4K2   B3NHT6   V5G1I3   D6WN49   A0A1I8M2D3   Q8I8E2   A0A1B3TNZ7   A0A2E4J7M2   A0A182MAA4   A0A0K8WL22   A0A182H9P0   A0A182K9L9   A0A099ZWT2   Q52NW5   A0A1I8NW71   A0A1I8QDI6   A0A182Q608   A0A232ET09   Q4V440  

EC Number

3.4.21.1
3.4.21.4

Pubmed

19121390    28756777    26227816    22118469    26354079    26108605    + More
18362917    19820115    10612046    29337314    17994087    20566863    25315136    14525923    17651235    17550304    12364791    20966253    22509400    9295327    20798317    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    25830018    20353571    30400621    15632085    24438588    17510324    7808473    21292972    17573377    8620885    27553646    26483478    17502004    28648823   

EMBL

BABH01010245    ODYU01009360    SOQ53730.1    ODYU01003944    SOQ43317.1    KZ150000    + More
PZC75312.1    JTDY01001347    KOB74130.1    JTDY01006244    KOB66174.1    NWSH01001202    PCG72143.1    KOB74133.1    AGBW02008010    OWR54306.1    KQ460045    KPJ18047.1    BABH01010242    BABH01010243    ODYU01002383    SOQ39812.1    KQ459324    KPJ01456.1    KOB74131.1    JTDY01005274    KOB67168.1    KOB74132.1    ODYU01001393    SOQ37513.1    KPJ01455.1    OWR54305.1    ODYU01006324    SOQ48069.1    JRES01001422    KNC23046.1    JXJN01007177    KQ971354    EFA07583.1    UFQT01002465    SSX33525.1    UFQS01003363    UFQT01003363    SSX15542.1    SSX34906.1    CAQQ02171618    CAQQ02171619    Y17904    CAA76928.1    NZWM01000032    MAQ69946.1    CH916375    EDV98091.1    DS235883    EEB20302.1    AY232168    AAR10191.1    DQ356025    ABC88740.1    EU869219    ACF93734.1    EU869872    ACF98290.1    IACF01002059    LAB67729.1    JRES01000827    KNC28039.1    AXCN02001863    CM000159    EDW94703.1    DQ356024    ABC88739.1    AAAB01008980    EAU76138.2    CH916366    EDV96186.1    APCN01005255    HQ878386    ADY17978.1    KQ971372    EFA10697.1    CH933809    EDW17926.1    AB002407    BAA22400.1    KZ288316    PBC28310.1    IACF01002060    LAB67730.1    GL435530    EFN73265.1    CAQQ02388900    CAQQ02035930    AE014296    AY089278    AAF49326.2    AAL90016.1    CH480815    EDW41898.1    GBXI01013758    JAD00534.1    EZ422800    ADD19076.1    MK075162    AYV99565.1    CM000071    EAL26143.1    EU095344    ABU49589.1    ATLV01020656    KE525304    KFB45482.1    CH477491    EAT40037.1    X74304    CAA52357.1    KA645497    AFP60126.1    CH916368    EDW02911.1    GL732540    EFX82212.1    AM765877    CAO78778.1    MK075184    AYV99587.1    CH479183    EDW35582.1    X94691    CCAG010022336    CCAG010022337    CCAG010022338    CH902618    EDV40496.2    CH954178    EDV51951.1    GALX01004586    JAB63880.1    KQ971342    EFA04551.1    AY155564    AAN75002.1    KU925752    AOG75377.1    PAVX01000020    MBE37760.1    AXCM01001005    GDHF01000734    JAI51580.1    JXUM01030427    KQ560884    KXJ80485.1    KL869824    KGL86182.1    AY995188    AAX94742.1    AXCN02000888    NNAY01002348    OXU21493.1    BT023166    AAY55582.1   

Proteomes

UP000005204    UP000037510    UP000218220    UP000007151    UP000053240    UP000053268    + More
UP000091820    UP000037069    UP000092460    UP000007266    UP000092443    UP000075885    UP000015102    UP000001070    UP000009046    UP000095301    UP000092445    UP000075886    UP000002282    UP000007062    UP000075882    UP000075840    UP000075880    UP000009192    UP000242457    UP000075902    UP000000311    UP000000803    UP000001292    UP000001819    UP000030765    UP000008820    UP000075900    UP000000305    UP000008744    UP000092444    UP000007801    UP000008711    UP000075883    UP000069940    UP000249989    UP000075881    UP000053858    UP000095300    UP000215335   

PRIDE

H9J0R7    H9J0R6    O97398    Q8T4A8    Q4V440   

Pfam

PF00089   Trypsin        + More
PF03454   MoeA_C

Interpro

IPR009003   Peptidase_S1_PA        + More
IPR001314   Peptidase_S1A       
IPR001254   Trypsin_dom       
IPR018114   TRYPSIN_HIS       
IPR033116   TRYPSIN_SER       
IPR005111   MoeA_C_domain_IV       
IPR036425   MoaB/Mog-like_dom_sf       
IPR036688   MoeA_C_domain_IV_sf       

SUPFAM

SSF50494   SSF50494        + More
SSF53218   SSF53218       
SSF63867   SSF63867       

Gene 3D

2.40.340.10     3.40.980.10    

CDD

cd00190  Tryp_SPc

ProteinModelPortal

H9J0R7   A0A2H1WKW7   A0A2H1VR93   A0A2W1BJQ7   A0A0L7LFE7   A0A0L7KT34   + More
A0A2A4JL27   A0A0L7LF03   A0A212FKP7   A0A194RKI2   H9J0R6   A0A2H1VHC8   A0A194QDC4   A0A0L7LG02   A0A0L7KVC9   A0A0L7LF91   A0A2H1V9I9   A0A194Q913   A0A212FKM8   A0A2H1W4Q5   A0A1A9WKQ0   A0A0L0BSQ2   A0A1B0B1H8   D6WPA6   A0A1A9XWP6   A0A336MUY7   A0A336MXC4   A0A182PK66   T1H2V5   O97398   A0A2D9XLI4   B4JVV3   E0W3U6   A0A1I8M656   A0A1A9Z6S9   Q6XHL5   A1XG66   B5APZ4   B5AQM2   A0A2P2I159   A0A0L0C9D3   A0A182QJV9   B4PJL5   A1XG65   A0NG43   B4J3I4   A0A182KJU0   A0A182IGM8   F1DQG5   D6WZJ8   A0A182IN32   B4KZJ9   O15944   A0A2A3E9B5   A0A182UJ75   A0A2P2I1H3   E1ZZV4   T1GX22   T1GQB9   Q8T4A8   B4HKU3   A0A0A1WN98   D3TMZ8   A0A3G5BIF4   Q28Y22   A7UNZ4   A0A1I8M4V1   A0A084W5I8   A0A1I8M4V2   Q16ZF3   Q25081   T1P9U9   A0A182RAB0   B4JBA6   E9GE64   A7DYX5   A0A3G5BIH9   B4GGG2   P51588   A0A1B0FLW7   B3M4K2   B3NHT6   V5G1I3   D6WN49   A0A1I8M2D3   Q8I8E2   A0A1B3TNZ7   A0A2E4J7M2   A0A182MAA4   A0A0K8WL22   A0A182H9P0   A0A182K9L9   A0A099ZWT2   Q52NW5   A0A1I8NW71   A0A1I8QDI6   A0A182Q608   A0A232ET09   Q4V440  

PDB

3TGJ     E-value=1.55785e-11,     Score=163

KEGG

101737878    no KO assigned | (RefSeq) uncharacterized LOC101737878

GO

GO:0004252   GO:0007586   GO:0005615   GO:0030574   GO:0008236   GO:0032324   GO:0006508   GO:0004368   GO:0006072   GO:0009331   GO:0005634   GO:0006289   GO:0004518   GO:0006281   GO:0048384  

Subcellular location

  

Length:

184

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0154

Exp number, first 60 AAs:

0.00531999999999999

Total prob of N-in:

0.01545

outside

1  -  184

 

 

Pi

120.7047

Theta

109.458241

Tajima's D

0.322364

CLR

60.746685

CSRT

0.464776761161942

Interpretation

Uncertain