Gene

KWMTBOMO02242  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA003049

Annotation

glycerol-3-phosphate_dehydrogenase_isoform_2_[Bombyx_mori]

Location

Bomo_Chr4(+):14520296-14547212      View in EpiBrowser

Full name

Glycerol-3-phosphate dehydrogenase      

Location in the cell

Mitochondrial   Reliability : 2.936

CDS

ATGTCTAGAAGAAGAATTATTGCAAGTGGAGTAGCTGGCGTTGCGGGTGCAGCCTTAGCCGTGTGGGCCTTCTCCGCCGATGACTCTCCGGTTAACTGGTACTCAGCAGCAACAGTGTCAGCAAAGACCGTACGCAAGAAGCGTCCTCTGCCAACCAGAACAGAACAAGTGGCCAATCTCCAAGCTGGGCACACGTACGATTTGCTCATCATTGGAGGCGGCGCCACGGGAGTTGGGTGTGCACTCGATGCAACAACTAGAGGTCTCCGAACAGCCCTAGTAGAAGCAGACGATTTTGCTAGCGGTACATCCAGTAGAAGCACGAAGCTCATCCATGGCGGAGTCAGGTACCTACAAAAGGCCATCATGCAACTCGACTATGACCAGTACAAGATGGTTAAAGAGGCTCTGCACGAGCGCGCTAATATGCTGGAAGTCGCACCACACTTGACTAGGCCCCTGCCTATTCTTCTACCAGTATACAAATGGTGGCAAGTACCGTATTATTGGTTCGGTATTAAAATGTACGATTTCGTTGCCGGCGACAGAAACGTTAAGAATTCTTATTATTTATCGAAGAAGAATACTCTTGAGTTGTTTCCAATGTTGAAATCGGATAATCTATGCGGAGGAATTGTCTATTATGATGGACAACAAGACGACGCTCGAATGAACTTAGCGATTGCACTGACGGCCGCCCGTCACGGCGCCACCATTGCTAACCACGTCAGCGTCACCAAACTATACAAGGTAGCCGGGAAACTGAGCGGAGCTAGACTGAAGGACGAGTTATCCGGCAAGGAATGGGACGTGCAAGCAAAGTGCATTATCAACGCAACCGGCCCATTCACGGACAGCATCAGGAAAATGGACGATCCCAAAATCAAAGATATCTGCTGTCCATCTTCAGGAGTACATATTGTGTTACCCGGATATTACAGTCCCGAACACATGGGCCTGCTAGACCCGGCAACATCCGACGGCCGCGTCATCTTCTTCTTGCCGTGGCTGAAGGGTACCATCGCCGGAACAACGGACCTGCCCTGCCAAGTCACCCACAACCCTAAACCCACTGAAGACGAAATCATGTTCATCCTTAGCGAAGTCAAGAACTATTTGAATCCGGACGTTGAAGTCCGGCGCGGTGACGTTCTGTCCGCGTGGTCCGGGATCCGGCCGCTAGTGTCGGACCCGAACAAGCCGGACACGCAGTCCCTGGCGCGGAACCACATCGTGCACGTGTCGCCGTCCGGCCTCGTCACCATCGCGGGCGGCAAGTGGACCACGTATCGGTCCATGGCCGCCGAGACCATAGATGCCGCTGTGGAAAGTGCAAATCTCAAACCAATCTTCAGGGACAGTCAGACTGATGGATTCTTAATAGAGGGAGCCCACGGATGGACTCCTACTATGTACATCAGATTGGTGCAAGATTTCGGATTGGAGATGGAAGTCGCCCAGCATTTGTCGAAGTCGTACGGGGACAGAGCGTTTGCTGTTGCCAAGATGGCGACCATGACCGGGAAGAGATGGCCAATCATCGGCAAGAAAATACACCCTGAGTTCCCGTATATAGACGCTGAGATTCGGTATGGAGTCCGTGAATATGCCTGTACAGCTATAGATATGATAGCTAGACGACTTCGTCTCGCCTTCCTCAACGTTCAAGCGGCCGCCGAAGCACTGCCCGTTGTCGTTGACATCATGGCCGAGGAACTCAACTGGAACGAGGCTGAAAGGAAGCGTCAAATTAAAATGGCAAACGAATTCCTTGCAAACGAAATGGGCCAGATGGTGAACCGAGCTAGTCGCGACAAGATCCCCATCAACCTGAGCAAGGAGGAGATACAGACGTACATCAAACGCTTCCAGATCATAGACAAGGATCGGAAGGGATTCGTGTCTATTAACGACATTCGGAGGAGTCTTAAGAACTACGGCGAGGAAGTGACCGGCGAGCAGCTCCACGAGATCCTACGCGAGATCGACACAAACATGAACGGTCAAGTTGAACTCGACGAGTATCTACAGATGATGTCGGCCATTAAATCTGGTCACGTGGCGTACTCGCGTTTCGCTCGAATGGCCGAGATGGAGGAGGAGCATCATGAAAGGGAAACCCTGAAAAAGAAGATCACCGTAGAGAGGAGCGGCGGTGGACTGTAA

Protein

MSRRRIIASGVAGVAGAALAVWAFSADDSPVNWYSAATVSAKTVRKKRPLPTRTEQVANLQAGHTYDLLIIGGGATGVGCALDATTRGLRTALVEADDFASGTSSRSTKLIHGGVRYLQKAIMQLDYDQYKMVKEALHERANMLEVAPHLTRPLPILLPVYKWWQVPYYWFGIKMYDFVAGDRNVKNSYYLSKKNTLELFPMLKSDNLCGGIVYYDGQQDDARMNLAIALTAARHGATIANHVSVTKLYKVAGKLSGARLKDELSGKEWDVQAKCIINATGPFTDSIRKMDDPKIKDICCPSSGVHIVLPGYYSPEHMGLLDPATSDGRVIFFLPWLKGTIAGTTDLPCQVTHNPKPTEDEIMFILSEVKNYLNPDVEVRRGDVLSAWSGIRPLVSDPNKPDTQSLARNHIVHVSPSGLVTIAGGKWTTYRSMAAETIDAAVESANLKPIFRDSQTDGFLIEGAHGWTPTMYIRLVQDFGLEMEVAQHLSKSYGDRAFAVAKMATMTGKRWPIIGKKIHPEFPYIDAEIRYGVREYACTAIDMIARRLRLAFLNVQAAAEALPVVVDIMAEELNWNEAERKRQIKMANEFLANEMGQMVNRASRDKIPINLSKEEIQTYIKRFQIIDKDRKGFVSINDIRRSLKNYGEEVTGEQLHEILREIDTNMNGQVELDEYLQMMSAIKSGHVAYSRFARMAEMEEEHHERETLKKKITVERSGGGL

Catalytic Activity

a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate

Cofactor

FAD

Similarity

Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

Feature

chain  Glycerol-3-phosphate dehydrogenase

Uniprot

C9EJW5   B0EVL7   A0A2A4J8H6   A0A2H1VKH5   A0A2A4J9N7   A0A212F3S6   + More
A0A194PMD4   A0A2R4SDR8   A0A1B6DUY3   A0A1L8E0W3   A0A310ST21   K7JBG8   A0A0C9RD27   A0A026WSS6   E9ILW1   A0A1L8E0R2   A0A1L8E0R5   B4J7V1   A0A1B6J9Z2   A0A0T6ATN2   A0A1Y1K9X7   A0A1B0CT95   V9IC36   A0A034VQV3   W8BGX8   A0A158NPA2   A0A0M9AA42   A0A034VNY6   A0A1B6E7D0   A0A0L0CBN8   B4H700   Q28WL2   A0A0A1X4X9   A0A067RNM6   B4MJK7   A0A139WHK5   A0A3B0JHL0   A0A195DYA8   A0A0J9RDU7   E0VPS4   B4HSG0   A0A087ZSL0   A0A1W4ULC4   A0A2A3EEM3   T1P9G5   B4P6V2   A0A1I8MW37   B4KRA5   B3NQ13   B3MCF1   A0A0L7QSS0   A0A0M3QVA0   A0A1I8PY97   B4LKQ7   B4QGZ4   Q7K569   D6WMX6   V9IAA7   A0A336MQ85   N6TNJ0   U5EWV1   A0A336MVE8   A0A1J1J686   A0A154PRP5   A0A182JZR5   A0A182MAB2   A0A182Y8Y4   A0A084WP96   A0A182QIQ4   A0A182SXE7   A0A182PLJ4   A0A182VGZ0   A0A182KZR0   F5HLN4   A0A182HYI1   A0A0A9YBB7   F5HLN3   A0A182XF89   A0A182TE52   A0A182RT17   A0A182NL33   B0W992   A0A182W3A7   A0A1Q3FKN3   A0A1Q3FKQ9   A0A182J426   A0A2M4BFD6   A0A182FQ71   A0A182GR19   A0A023EVQ4   A0A2M3ZKN2   A0A2M3YYI4   A0A2M4A6Z9   A0A2M4BF57   E2B8P5   A0A151WXK2   T1DK36   Q17E81   A0A195CIF7   Q17E82  

EC Number

1.1.5.3

Pubmed

19121390    22118469    26354079    20075255    24508170    30249741    + More
21282665    17994087    28004739    25348373    24495485    21347285    26108605    15632085    23185243    25830018    24845553    18362917    19820115    22936249    20566863    17550304    25315136    18057021    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    23537049    25244985    24438588    20966253    12364791    14747013    17210077    25401762    26823975    26483478    24945155    20798317    17510324   

EMBL

GQ865685    GQ865686    ACV95334.1    BABH01010255    BABH01010256    BABH01010257    + More
EF154335    GQ865687    GQ865688    ABM46603.2    ACV95336.1    NWSH01002494    PCG68169.1    ODYU01003054    SOQ41349.1    PCG68170.1    AGBW02010507    OWR48372.1    KQ459598    KPI94596.1    MF101766    AVZ46903.1    GEDC01027407    GEDC01007815    JAS09891.1    JAS29483.1    GFDF01001765    JAV12319.1    KQ760505    OAD60070.1    AAZX01012716    GBYB01011047    JAG80814.1    KK107119    QOIP01000009    EZA58721.1    RLU18934.1    GL764129    EFZ18296.1    GFDF01001766    JAV12318.1    GFDF01001764    JAV12320.1    CH916367    EDW01157.1    GECU01018991    GECU01011679    GECU01006943    GECU01005602    JAS88715.1    JAS96027.1    JAT00764.1    JAT02105.1    LJIG01022836    KRT78466.1    GEZM01088494    GEZM01088493    JAV58164.1    AJWK01027296    AJWK01027297    AJWK01027298    AJWK01027299    JR037925    AEY58036.1    GAKP01014782    GAKP01014778    JAC44170.1    GAMC01006035    JAC00521.1    ADTU01022311    KQ435718    KOX78959.1    GAKP01014783    GAKP01014779    GAKP01014775    GAKP01014774    GAKP01014772    JAC44169.1    GEDC01011959    GEDC01003457    JAS25339.1    JAS33841.1    JRES01000644    KNC29671.1    CH479216    EDW33636.1    CM000071    EAL26655.1    KRT03276.1    GBXI01008110    JAD06182.1    KK852561    KDR21344.1    CH963846    EDW72296.1    KQ971343    KYB27335.1    OUUW01000001    SPP72726.1    KQ980066    KYN17895.1    CM002911    KMY94096.1    DS235371    EEB15380.1    CH480816    EDW48038.1    KZ288266    PBC30205.1    KA644553    AFP59182.1    CM000158    EDW92029.1    CH933808    EDW09321.1    CH954179    EDV55860.1    CH902619    EDV37275.1    KPU76675.1    KQ414756    KOC61599.1    CP012524    ALC42013.1    CH940648    EDW61780.1    CM000362    EDX07257.1    AE013599    AY051430    AAF58099.2    AAK92854.1    EFA04316.2    JR037924    AEY58035.1    UFQS01002125    UFQT01002125    SSX13277.1    SSX32714.1    APGK01028342    APGK01028343    APGK01028344    APGK01028345    KB740686    KB631930    ENN79553.1    ERL87310.1    GANO01001254    JAB58617.1    SSX13276.1    SSX32713.1    CVRI01000074    CRL07917.1    KQ435090    KZC14579.1    AXCM01001209    ATLV01024994    KE525367    KFB52040.1    AXCN02000087    AAAB01008898    EGK97166.1    APCN01005372    GBHO01013227    GBRD01010063    GDHC01000856    JAG30377.1    JAG55761.1    JAQ17773.1    EGK97167.1    DS231862    EDS39789.1    GFDL01006927    JAV28118.1    GFDL01006930    JAV28115.1    GGFJ01002562    MBW51703.1    JXUM01082801    KQ563337    KXJ74027.1    GAPW01000330    JAC13268.1    GGFM01008343    MBW29094.1    GGFM01000565    MBW21316.1    GGFK01003243    MBW36564.1    GGFJ01002544    MBW51685.1    GL446361    EFN87951.1    KQ982668    KYQ52497.1    GAMD01001146    JAB00445.1    CH477284    EAT44796.1    KQ977791    KYM99848.1    EAT44797.1   

Proteomes

UP000005204    UP000218220    UP000007151    UP000053268    UP000002358    UP000053097    + More
UP000279307    UP000001070    UP000092461    UP000005205    UP000053105    UP000037069    UP000008744    UP000001819    UP000027135    UP000007798    UP000007266    UP000268350    UP000078492    UP000009046    UP000001292    UP000005203    UP000192221    UP000242457    UP000002282    UP000095301    UP000009192    UP000008711    UP000007801    UP000053825    UP000092553    UP000095300    UP000008792    UP000000304    UP000000803    UP000019118    UP000030742    UP000183832    UP000076502    UP000075881    UP000075883    UP000076408    UP000030765    UP000075886    UP000075901    UP000075885    UP000075903    UP000075882    UP000007062    UP000075840    UP000076407    UP000075902    UP000075900    UP000075884    UP000002320    UP000075920    UP000075880    UP000069272    UP000069940    UP000249989    UP000008237    UP000075809    UP000008820    UP000078542   

PRIDE

C9EJW5    B0EVL7   

Pfam

PF01266   DAO        + More
PF16901   DAO_C
PF13499   EF-hand_7
PF00096   zf-C2H2
PF13833   EF-hand_8

Interpro

IPR036188   FAD/NAD-bd_sf        + More
IPR018247   EF_Hand_1_Ca_BS       
IPR031656   DAO_C       
IPR006076   FAD-dep_OxRdtase       
IPR038299   DAO_C_sf       
IPR002048   EF_hand_dom       
IPR000447   G3P_DH_FAD-dep       
IPR011992   EF-hand-dom_pair       
IPR006311   TAT_signal       
IPR036236   Znf_C2H2_sf       
IPR013087   Znf_C2H2_type       

SUPFAM

SSF51905   SSF51905        + More
SSF47473   SSF47473       
SSF57667   SSF57667       

Gene 3D

1.10.8.870     3.50.50.60    

CDD

cd00051  EFh

ProteinModelPortal

C9EJW5   B0EVL7   A0A2A4J8H6   A0A2H1VKH5   A0A2A4J9N7   A0A212F3S6   + More
A0A194PMD4   A0A2R4SDR8   A0A1B6DUY3   A0A1L8E0W3   A0A310ST21   K7JBG8   A0A0C9RD27   A0A026WSS6   E9ILW1   A0A1L8E0R2   A0A1L8E0R5   B4J7V1   A0A1B6J9Z2   A0A0T6ATN2   A0A1Y1K9X7   A0A1B0CT95   V9IC36   A0A034VQV3   W8BGX8   A0A158NPA2   A0A0M9AA42   A0A034VNY6   A0A1B6E7D0   A0A0L0CBN8   B4H700   Q28WL2   A0A0A1X4X9   A0A067RNM6   B4MJK7   A0A139WHK5   A0A3B0JHL0   A0A195DYA8   A0A0J9RDU7   E0VPS4   B4HSG0   A0A087ZSL0   A0A1W4ULC4   A0A2A3EEM3   T1P9G5   B4P6V2   A0A1I8MW37   B4KRA5   B3NQ13   B3MCF1   A0A0L7QSS0   A0A0M3QVA0   A0A1I8PY97   B4LKQ7   B4QGZ4   Q7K569   D6WMX6   V9IAA7   A0A336MQ85   N6TNJ0   U5EWV1   A0A336MVE8   A0A1J1J686   A0A154PRP5   A0A182JZR5   A0A182MAB2   A0A182Y8Y4   A0A084WP96   A0A182QIQ4   A0A182SXE7   A0A182PLJ4   A0A182VGZ0   A0A182KZR0   F5HLN4   A0A182HYI1   A0A0A9YBB7   F5HLN3   A0A182XF89   A0A182TE52   A0A182RT17   A0A182NL33   B0W992   A0A182W3A7   A0A1Q3FKN3   A0A1Q3FKQ9   A0A182J426   A0A2M4BFD6   A0A182FQ71   A0A182GR19   A0A023EVQ4   A0A2M3ZKN2   A0A2M3YYI4   A0A2M4A6Z9   A0A2M4BF57   E2B8P5   A0A151WXK2   T1DK36   Q17E81   A0A195CIF7   Q17E82  

PDB

3DA1     E-value=1.34895e-70,     Score=679

KEGG

100037430    K00111 glycerol-3-phosphate dehydrogenase [EC:1.1.5.3] | (RefSeq) Gpd, l(b001); glycerol-3-phosphate

PATHWAY

00564    Glycerophospholipid metabolism - Bombyx mori (domestic silkworm)

GO

GO:0009331   GO:0052591   GO:0006072   GO:0005509   GO:0003676   GO:0016021   GO:0007629   GO:0006127   GO:0005743   GO:0004367   GO:0046168   GO:0004368   GO:0005739   GO:0006071   GO:0016491   GO:0005634   GO:0006289   GO:0004518   GO:0006281   GO:0048384   GO:0055114  

PANTHER

PTHR11985  

Length:

721

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

18.7717199999999

Exp number, first 60 AAs:

18.2224

Total prob of N-in:

0.93691

POSSIBLE N-term signal

sequence

inside

1  -  6

TMhelix

7  -  26

outside

27  -  721

 

 

Pi

217.159985

Theta

155.465668

Tajima's D

1.271299

CLR

0.826267

CSRT

0.728163591820409

Interpretation

Uncertain