Gene

KWMTBOMO02239

Pre Gene Modal

BGIBMGA003107

Annotation

PREDICTED:_histone-lysine_N-methyltransferase_SETD2_isoform_X2_[Bombyx_mori]

Location

Bomo_Chr4(-):14495550-14500015      View in EpiBrowser

Full name

Histone-lysine N-methyltransferase      

Location in the cell

Nuclear   Reliability : 4.193

CDS

ATGTCAGTCGAGGACAGTATAAATGATAGAAACTTTTTATTCCAAGCAGAGGACAGTTCATCGGACGAAGAGGAGCAATTGAACAGCTCTTTGGACAGTCCGCTGGTGATGCGACATGCTAAAGGGAAACTTGTTGAAGGGGTCAATGGTATATATGAAGTAATCAAAGAAGATGCTCAGAATGGTTTGATACCGGAGCACGCACTTCTTCACATGAGGCCAAGGAAACGAAGAGTTGGATTAGTTTCAGAAAGACCTATAAGTCCTCGTACGGAAGAGGACAAATTAGCAGGAAAATTAGAAATCAAACGATATAAACAGACTAAAGAGAAACTTCGAAGACGTCGTGAGAAATTACTGCAGAAGGTAATGCTGGCTTCCGGGAAACTCAAACTCAGACCTGGACAGGCAAAATTACCCCTGTTAGACTTATCCGAGATAGACAGCGGGAGTGAATCGGATTCGGACGAGGCGGAGAAGTTGTGCTCTGGGTCGGCGAGCGTGCCTCCCGCTGTCCCCGCGCCCCCCGCCCCCGCCCCCGCCGCCGTGAGCGCGGAGACGTCGCGGCGCATCAAGGAGCAGTTCCGCAGCGCGATGGCGGGCGTCATGGTGCAGCACCTCAACCCGTACCGCCACTCGGACGCGCCGGCCGGCAGGATCACGTGCACCGCTGACTTTAAACACCTCGCCAGAAAGTTAACACACTTCGTAATGTTGAAAGAACTGAAACATTGCCGCTCCGTCGAGGAACTTGTCGTCACCGATTCTGTACGATCTAAAGCGAAGACTTTCGTCAAAAAATACATGGCCAAGTTCGGTCCGGTGTACAAACGGCCACCCGAGGAAGCAGACTAG

Protein

MSVEDSINDRNFLFQAEDSSSDEEEQLNSSLDSPLVMRHAKGKLVEGVNGIYEVIKEDAQNGLIPEHALLHMRPRKRRVGLVSERPISPRTEEDKLAGKLEIKRYKQTKEKLRRRREKLLQKVMLASGKLKLRPGQAKLPLLDLSEIDSGSESDSDEAEKLCSGSASVPPAVPAPPAPAPAAVSAETSRRIKEQFRSAMAGVMVQHLNPYRHSDAPAGRITCTADFKHLARKLTHFVMLKELKHCRSVEELVVTDSVRSKAKTFVKKYMAKFGPVYKRPPEEAD

Catalytic Activity

L-lysyl-[histone] + S-adenosyl-L-methionine = H(+) + N(6)-methyl-L-lysyl-[histone] + S-adenosyl-L-homocysteine

Uniprot

H9J0S0   A0A194PPE0   A0A0N1ID98   A0A2J7Q0P0   A0A2J7Q0N0   A0A2J7Q0M6   + More
A0A2J7Q0Q2   A0A2J7Q0M9   A0A067RKL1   U4UHI0   A0A336MYX7   A0A1B6LEX6   A0A336KJ69   N6TEM2   U4TSV6   A0A232EII4   K7IRL9   A0A1B6M7P2   A0A195BYH0   A0A158NP25   A0A151XDR9   A0A151IU07   A0A195EZU0   F4WGJ7   A0A0L7REB6   A0A2A3E6P6   A0A088AJJ3   E9IEB7  

EC Number

2.1.1.43

Pubmed

19121390    26354079    24845553    23537049    28648823    20075255    + More
21347285    21719571    21282665   

EMBL

BABH01010259    KQ459598    KPI94599.1    KQ461183    KPJ07564.1    NEVH01019965    + More
PNF22141.1    PNF22144.1    PNF22142.1    PNF22139.1    PNF22143.1    KK852415    KDR24367.1    KB632357    ERL93439.1    UFQT01004216    SSX35574.1    GEBQ01017729    JAT22248.1    UFQS01000436    UFQT01000436    SSX03918.1    SSX24283.1    APGK01040621    KB740984    ENN76193.1    KB630727    ERL83822.1    NNAY01004253    OXU18144.1    GEBQ01008113    JAT31864.1    KQ976394    KYM93355.1    ADTU01022133    ADTU01022134    KQ982268    KYQ58499.1    KQ980983    KYN10781.1    KQ981891    KYN33825.1    GL888137    EGI66662.1    KQ414612    KOC69170.1    KZ288349    PBC27388.1    GL762576    EFZ21071.1   

Proteomes

UP000005204    UP000053268    UP000053240    UP000235965    UP000027135    UP000030742    + More
UP000019118    UP000215335    UP000002358    UP000078540    UP000005205    UP000075809    UP000078492    UP000078541    UP000007755    UP000053825    UP000242457    UP000005203   

PRIDE

H9J0S0   

Pfam

PF08236   SRI        + More
PF00397   WW
PF17907   AWS
PF00856   SET

Interpro

IPR013257   SRI        + More
IPR001202   WW_dom       
IPR038190   SRI_sf       
IPR036020   WW_dom_sf       
IPR042294   SETD2       
IPR003616   Post-SET_dom       
IPR006560   AWS_dom       
IPR001214   SET_dom       
IPR017956   AT_hook_DNA-bd_motif       

SUPFAM

SSF51045   SSF51045       

Gene 3D

1.10.1740.100    

CDD

cd00201  WW

ProteinModelPortal

H9J0S0   A0A194PPE0   A0A0N1ID98   A0A2J7Q0P0   A0A2J7Q0N0   A0A2J7Q0M6   + More
A0A2J7Q0Q2   A0A2J7Q0M9   A0A067RKL1   U4UHI0   A0A336MYX7   A0A1B6LEX6   A0A336KJ69   N6TEM2   U4TSV6   A0A232EII4   K7IRL9   A0A1B6M7P2   A0A195BYH0   A0A158NP25   A0A151XDR9   A0A151IU07   A0A195EZU0   F4WGJ7   A0A0L7REB6   A0A2A3E6P6   A0A088AJJ3   E9IEB7  

PDB

2A7O     E-value=3.89353e-21,     Score=248

KEGG

101738271    K11423 histone-lysine N-methyltransferase SETD2 [EC:2.1.1.43] | (RefSeq) histone-lysine N-methyltran

GO

GO:0005694   GO:0006355   GO:0018024   GO:0005634   GO:0003677   GO:0003697   GO:0004519   GO:0006289   GO:0004518   GO:0006281   GO:0048384   GO:0034968  

PANTHER

PTHR46711  

Subcellular location

Nucleus  

Length:

284

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0

Exp number, first 60 AAs:

0

Total prob of N-in:

0.05519

outside

1  -  284

 

 

Pi

23.559725

Theta

30.837677

Tajima's D

-1.629496

CLR

1.874091

CSRT

0.0427478626068697

Interpretation

Uncertain