Gene

KWMTBOMO02236

Annotation

PREDICTED:_uncharacterized_protein_LOC105842306_[Bombyx_mori]

Location

Bomo_Chr4(-):14453597-14455385      View in EpiBrowser

Full name

Carboxypeptidase       + More
Alpha-1,4 glucan phosphorylase      

Location in the cell

Nuclear   Reliability : 2.852

CDS

ATGAGTAGAGACGTGAAAAAACGACAAGTCAGCACTGACCAACTAATGATGCTATTGGATTTCCTCAAAGAGCATCCTGATCTAGCTAAAGGCAAAGTGAGGCGGCATCGAACCAAGTTCAGCCCTGTGAAATTGTGGAATTTATGTGCGAAAAAACTCAACACGGTCAGAGACGGTGCCGTAAAGGACGGGAAAGGGTGGTCAAGGTATTGGTGTGATTGGAAGTACCGTGCCAAAAGAAGAGCATTAGAGATAAAAGCTGCCAAGAACAACCAAAAACCGTTGCCCGAAGATTTCACTCAACTGTCTTCAACCGAAGAGACAATTCTAAGTATCATCGGTCACAGCTGCATTGATGATATATTCATTAAAACTGATCCACTTGCTCAAGTAAGTGTTCAGTGTGTAATATTATTTATTGCTGATGATATCGGTGGTGGCAGTGTATAA

Protein

MSRDVKKRQVSTDQLMMLLDFLKEHPDLAKGKVRRHRTKFSPVKLWNLCAKKLNTVRDGAVKDGKGWSRYWCDWKYRAKRRALEIKAAKNNQKPLPEDFTQLSSTEETILSIIGHSCIDDIFIKTDPLAQVSVQCVILFIADDIGGGSV

Description

Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

Catalytic Activity

[(1->4)-alpha-D-glucosyl](n) + phosphate = [(1->4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate

Cofactor

pyridoxal 5'-phosphate

Similarity

Belongs to the peptidase S10 family.
Belongs to the glycogen phosphorylase family.

Uniprot

H9J0S2   A0A2A4JZP3   A0A0L7L2F9   A0A2H1VSJ2   H9JR50   S4PSQ3   + More
A0A212FLX0   A0A1E1WCS8   A0A2A4JBL2   A0A087U8S3   A0A2H1WGB2   A0A087V1F0   A0A293LNC5   A0A194QPF3   A0A194Q9V8   A0A0L7KRX8   A0A0N1PIY8   A0A194PNW3   A0A0L7L021   A0A194PPV5   A0A2A4JD63   A0A0N1PIH4   A0A194PPI4   A0A2H1VJB6   J9LFZ8   A0A2A4JS97   A0A2H1X3F6   A0A194PZ71   S4P2L6   A0A2H1X3Z7   A0A2S2NH70   A0A0J7KAS1   H9IVT5   H9JGC7   A0A1B0AIK9   A0A026VT74   A0A2A4JAS9   A0A0L7LU47   A0A2H1WKZ2   A0A212ESB7   A0A3L8DY89   A0A1A9WPM8   A0A151IL77   S4NIT4   A0A2H1W046   A0A194PNP2   A0A0L0BSY9   A0A034WCK6   A0A0L7K4A1   A0A151JAQ3   A0A3L8D7T4   X1X859   A0A0J7JYY0   A0A151J8E2   J9KL28   A0A3L8D8X5   A0A1I8NGT8   A0A0A1WCW8   J9LJG3   J9JT59   X1X9A2   A0A2S2NZD8   J9JLN7   A0A2L2YAG4   A0A2L2YAG6   A0A0L7KNN1   J9KDG3   A0A087SVY6   A0A034WUH2  

EC Number

3.4.16.-
2.4.1.1

Pubmed

19121390    26227816    23622113    22118469    26354079    24508170    + More
30249741    26108605    25348373    25315136    25830018    26561354   

EMBL

BABH01010262    BABH01010263    NWSH01000324    PCG77475.1    JTDY01003382    KOB69642.1    + More
ODYU01004191    SOQ43787.1    BABH01039741    GAIX01013388    JAA79172.1    AGBW02007695    OWR54731.1    GDQN01006252    JAT84802.1    NWSH01002002    PCG69465.1    KK118749    KFM73762.1    ODYU01008482    SOQ52119.1    KL822141    KFM83439.1    GFWV01004639    MAA29369.1    KQ461185    KPJ07413.1    KQ459252    KPJ02204.1    JTDY01006403    KOB66038.1    KQ460709    KPJ12735.1    KQ459598    KPI94673.1    JTDY01003974    KOB68755.1    KQ459596    KPI95347.1    NWSH01001816    PCG70037.1    KQ459717    KPJ20285.1    KPI94644.1    ODYU01002883    SOQ40925.1    ABLF02025568    ABLF02025570    ABLF02025574    NWSH01000765    PCG74343.1    ODYU01013119    SOQ59807.1    KQ459586    KPI98044.1    GAIX01006834    JAA85726.1    ODYU01013290    SOQ59997.1    GGMR01003886    MBY16505.1    LBMM01010385    KMQ87503.1    BABH01038066    BABH01002464    KK108011    EZA46983.1    NWSH01002294    PCG68644.1    JTDY01000079    KOB78990.1    ODYU01009309    SOQ53636.1    AGBW02012845    OWR44344.1    QOIP01000003    RLU24778.1    KQ977130    KYN05506.1    GAIX01013939    JAA78621.1    ODYU01005228    SOQ45884.1    KPI94603.1    JRES01001390    KNC23195.1    GAKP01006900    JAC52052.1    JTDY01011427    KOB56417.1    KQ979220    KYN22231.1    QOIP01000012    RLU15958.1    ABLF02016385    LBMM01020580    KMQ83254.1    KQ979542    KYN21089.1    ABLF02015400    QOIP01000011    RLU16774.1    GBXI01017503    JAC96788.1    ABLF02057071    ABLF02063456    ABLF02002502    ABLF02016430    GGMR01009982    MBY22601.1    ABLF02023667    IAAA01014055    LAA05159.1    IAAA01014056    LAA05162.1    JTDY01008402    KOB64584.1    ABLF02007995    KK112195    KFM57025.1    GAKP01000960    JAC57992.1   

Proteomes

UP000005204    UP000218220    UP000037510    UP000007151    UP000054359    UP000053240    + More
UP000053268    UP000007819    UP000036403    UP000092445    UP000053097    UP000279307    UP000091820    UP000078542    UP000037069    UP000078492    UP000095301   

PRIDE

H9J0S2    H9JR50    H9IVT5    H9JGC7   

Pfam

PF00450   Peptidase_S10        + More
PF13873   Myb_DNA-bind_5
PF10265   Miga
PF00343   Phosphorylase

Interpro

IPR001563   Peptidase_S10        + More
IPR029058   AB_hydrolase       
IPR018202   Ser_caboxypep_ser_AS       
IPR033124   Ser_caboxypep_his_AS       
IPR028002   Myb_DNA-bind_5       
IPR026753   NAIF1       
IPR019392   Miga       
IPR000811   Glyco_trans_35       

SUPFAM

SSF53474   SSF53474       

Gene 3D

3.40.50.1820    

ProteinModelPortal

H9J0S2   A0A2A4JZP3   A0A0L7L2F9   A0A2H1VSJ2   H9JR50   S4PSQ3   + More
A0A212FLX0   A0A1E1WCS8   A0A2A4JBL2   A0A087U8S3   A0A2H1WGB2   A0A087V1F0   A0A293LNC5   A0A194QPF3   A0A194Q9V8   A0A0L7KRX8   A0A0N1PIY8   A0A194PNW3   A0A0L7L021   A0A194PPV5   A0A2A4JD63   A0A0N1PIH4   A0A194PPI4   A0A2H1VJB6   J9LFZ8   A0A2A4JS97   A0A2H1X3F6   A0A194PZ71   S4P2L6   A0A2H1X3Z7   A0A2S2NH70   A0A0J7KAS1   H9IVT5   H9JGC7   A0A1B0AIK9   A0A026VT74   A0A2A4JAS9   A0A0L7LU47   A0A2H1WKZ2   A0A212ESB7   A0A3L8DY89   A0A1A9WPM8   A0A151IL77   S4NIT4   A0A2H1W046   A0A194PNP2   A0A0L0BSY9   A0A034WCK6   A0A0L7K4A1   A0A151JAQ3   A0A3L8D7T4   X1X859   A0A0J7JYY0   A0A151J8E2   J9KL28   A0A3L8D8X5   A0A1I8NGT8   A0A0A1WCW8   J9LJG3   J9JT59   X1X9A2   A0A2S2NZD8   J9JLN7   A0A2L2YAG4   A0A2L2YAG6   A0A0L7KNN1   J9KDG3   A0A087SVY6   A0A034WUH2  

KEGG

105842306    no KO assigned | (RefSeq) uncharacterized LOC105842306

GO

GO:0004185   GO:0006915   GO:0005634   GO:0008053   GO:0102499   GO:0008184   GO:0005975   GO:0102250   GO:0016021  

PANTHER

PTHR11802   PTHR23098   PTHR21508   PTHR11468  

Length:

149

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.03026

Exp number, first 60 AAs:

0

Total prob of N-in:

0.61732

inside

1  -  149

 

 

Pi

25.633179

Theta

23.399312

Tajima's D

0.291949

CLR

12.47353

CSRT

0.458177091145443

Interpretation

Uncertain