Gene

KWMTBOMO02235

Pre Gene Modal

BGIBMGA003110

Annotation

PREDICTED:_venom_serine_carboxypeptidase-like_[Papilio_xuthus]

Location

Bomo_Chr4(-):14420492-14444205      View in EpiBrowser

Full name

Carboxypeptidase       + More
Venom serine carboxypeptidase      

Location in the cell

PlasmaMembrane   Reliability : 1.26

CDS

ATGAAATTATTGACTTGTTTTTTGTTTGTTTTTATATGCAGCGTCTGCTGTAAAGTAGCGGTCAAAGATAAATCAACGAAATCGCTAAACAGCTTAGAAGATTCTAAAGTGAAAGAATTAAAAAATGATGACAATCAGGACGAGGAGACGCCCGCGACCGATACCCCTAAGGTCGATAATGGCGTGGCACTGATTCTAACGCCGTATATTGAAGAAGGGAGGCTGAATGAGGCCCGTGAGGACAGCCGAGTGGACAGGTCATTATTCTTTGGATACGAGAGTTACTCTGGTTACTTCACGGTGAACAAGACATACAATTCGAATTCGTTTTTCTGGTACTTCCCTGTTGTGAAGAAACCAGTGAAAAAGACACCGTGGGTGATCTGGCTGCAAGGAGGACCTGGTGCGTCGAGTCTCACGTCGTTGTTCAACGAGATCGGACCGTACAAGGTCACTCATAAAGGGAATTTATTGCCTTACCCCCACACGTGGTTGCAAAATCACTCGCTGGTGTTCATCGACAACCCCATCGGGACTGGGTTCAGTTTTACTGATAGCGAAGATGGATATGTACACGATATGGATACGTATGGTCACCACCTGTACTTAACAGTGAAGCAACTGGTGACAGTGTATCCGGAATTGCAAACTGCACCATTGTATGTGGCCGGAGAGTCGTACGCTGGTAAATACGTTCCAGCTTTGGCCATGCAACTTCACAGGCACAAAGACGACCCGGATTTCAATATAAATCTTCAGGGCTTGATAGTCGGCAACGCTTATGTTGATCCGGAAATGATATCTCACATGGCGCGACCGTTCTACTACTTCGGAATGCTGGAGAAGGAAGAGATAAAGGCCATACAGCCTCTACTGACAGCGCTCTCAGAGGACATTGCCGCTAATCGAAGTGTTGAGGCTAAGAACAGATTCATGGGATTGGTCTCGTTGCTTCTGTATCTATCGCATCAGACGCATGCGTACAATTTCCTTGAAGACCGCGTCGTTTTAGAGAATCACGAGAAGTTTCTCAATAAGCCCGAAATAAGAAAAGCAATTCACGTCGGAGACATAATATACACGTACGTGAACGTTACCGTGAATCTTAAGATGGCCCCGGACTTCCTTAGCAGTTCAAAAGCTCTTTACGAAGAGCTGCTGGAGAGCTATAGGGTGTTGACATACTGTGGAAACCTGGATCAGATGATGCCGTGCGTGGTCACATCGGAACATTATAGAACGTGGAAATGGAGTTCGTCCGATGACTTCATTAAGGCTGTACGAAATCCTTACATGTTTAAAAATAGACTGGCAGGGTACCACAAAACCGGCGGTAATCTAACGGAGCTGATCATCCGCGGAGCCGGTCACATGGCGCCCATGGACACGCCCGACCAAACAGCGTACTTCATAACTCAATGGACCCACAACGAACCGTTGGACCAACCGATCGGAACTACCATCGATTTGAAATACGTAGAAGAATATGTTAAGAAATTAATATTACCGACGTCTTGA

Protein

MKLLTCFLFVFICSVCCKVAVKDKSTKSLNSLEDSKVKELKNDDNQDEETPATDTPKVDNGVALILTPYIEEGRLNEAREDSRVDRSLFFGYESYSGYFTVNKTYNSNSFFWYFPVVKKPVKKTPWVIWLQGGPGASSLTSLFNEIGPYKVTHKGNLLPYPHTWLQNHSLVFIDNPIGTGFSFTDSEDGYVHDMDTYGHHLYLTVKQLVTVYPELQTAPLYVAGESYAGKYVPALAMQLHRHKDDPDFNINLQGLIVGNAYVDPEMISHMARPFYYFGMLEKEEIKAIQPLLTALSEDIAANRSVEAKNRFMGLVSLLLYLSHQTHAYNFLEDRVVLENHEKFLNKPEIRKAIHVGDIIYTYVNVTVNLKMAPDFLSSSKALYEELLESYRVLTYCGNLDQMMPCVVTSEHYRTWKWSSSDDFIKAVRNPYMFKNRLAGYHKTGGNLTELIIRGAGHMAPMDTPDQTAYFITQWTHNEPLDQPIGTTIDLKYVEEYVKKLILPTS

Catalytic Activity

Release of a C-terminal amino acid with broad specificity.

Similarity

Belongs to the peptidase S10 family.

Keywords

Allergen   Carboxypeptidase   Complete proteome   Glycoprotein   Hydrolase   Protease   Reference proteome   Secreted   Signal  

Feature

chain  Carboxypeptidase

Uniprot

A0A2A4K0D9   A0A0N1INC9   A0A194PNP2   A0A2A4K0P1   A0A2H1V3X3   A0A2H1V3Z0   + More
A0A212EN12   H9J0S5   A0A2A4JZQ9   A0A2P8YUZ9   R4V3H3   A0A2H1V444   A0A0L7KXC5   A0A146L8K2   A0A146M3S2   A0A1V1G5G1   A0A2J7RMM3   A0A220K8I1   A0A067RMV2   A0A0A9W0I2   A0A0A9X8H2   A0A0K8SL40   A0A0A9XDE9   A0A146L5J6   A0A1B6DAZ8   A0A2H1WQ98   A0A173FDK2   A0A1B6EFH6   A0A1B6G2E3   A0A1B6DKD2   F4X0L6   A0A195D1V5   A0A151WYN0   A0A195D9Z9   N6SSG5   A0A0L7LM79   E9IJU5   A0A195F7F6   A0A158ND03   A0A195B917   A0A1E1WAZ3   A0A336M1Q6   U4U2S4   A0A348G5Z8   A0A146LHK7   Q175U3   A0A0M8ZQT3   A0A182VDU4   A0A146L0Y9   A0A182NMB9   A0A182Y0S5   K7IV06   A0A170XJP7   A0A224XJN6   Q7Q789   A0A182HM77   A0A182LJS3   A0A182XCU7   A0A067QKM7   A0A146L6S5   A0A182PVV1   A0A0J7KEF9   A0A182QCW5   E2AY00   A0A026WJK0   A0A2R7WTA9   R4FLC5   A0A182UCJ9   A0A182TLN9   Q101N9   C9WMM5   E2AY01   A0A182BVG3   B0WNR6   A0A182H8I5   B3SNT5   A0A2H1VKQ6   A0A0A9XKA6   A8WH57   B3SNT4   D7EHX7   A0A1B6KAA3   A0A0A9XV56   A0A1B6FEW7   A0A0L7R680   A0A2A3EHH5   I4DN75   A0A182JGG1   A0A2M4DMN0   A0A182LU18   A0A1B6CQY1   K7IV07   A0A2A4K7Y2   A0A182H8I4   A0A146LT64  

EC Number

3.4.16.-
3.4.16.5

Pubmed

26354079    22118469    19121390    29403074    26227816    26823975    + More
28410430    28630352    24845553    25401762    27251284    21719571    23537049    21282665    21347285    17510324    25244985    20075255    12364791    14747013    17210077    20966253    20798317    24508170    30249741    24548612    17073008    26483478    27762356    18362917    19820115    22651552   

EMBL

NWSH01000324    PCG77476.1    KQ461183    KPJ07560.1    KQ459598    KPI94603.1    + More
PCG77478.1    ODYU01000565    SOQ35545.1    SOQ35547.1    AGBW02013763    OWR42868.1    BABH01010276    BABH01010277    BABH01010278    BABH01010279    PCG77477.1    PYGN01000345    PSN48057.1    KC571839    AGM32338.1    SOQ35546.1    JTDY01004651    KOB67907.1    GDHC01015187    JAQ03442.1    GDHC01004208    JAQ14421.1    FX985403    BAX07416.1    NEVH01002552    PNF42087.1    MF319693    ASJ26407.1    KK852415    KDR24388.1    GBHO01045227    GBHO01045224    JAF98376.1    JAF98379.1    GBHO01028516    GBHO01028513    GBRD01013050    JAG15088.1    JAG15091.1    JAG52776.1    GBRD01011805    GBRD01011803    JAG54021.1    GBHO01028515    GBHO01028514    JAG15089.1    JAG15090.1    GDHC01016222    JAQ02407.1    GEDC01014417    JAS22881.1    ODYU01010255    SOQ55239.1    KT182637    ANG83462.1    GEDC01000657    JAS36641.1    GECZ01013161    JAS56608.1    GEDC01011157    JAS26141.1    GL888498    EGI60008.1    KQ977012    KYN06384.1    KQ982650    KYQ52877.1    KQ981135    KYN09229.1    APGK01058732    KB741291    KB631579    ENN70579.1    ERL84453.1    JTDY01000595    KOB76535.1    GL763883    EFZ19168.1    KQ981744    KYN36373.1    ADTU01012128    KQ976558    KYM80684.1    GDQN01006939    JAT84115.1    UFQT01000421    SSX24175.1    KB631843    ERL86633.1    FX985537    BBF97871.1    GDHC01011620    JAQ07009.1    CH477395    EAT41862.1    KQ435896    KOX69240.1    GDHC01016591    JAQ02038.1    AAZX01001162    GEMB01004337    JAR98936.1    GFTR01006388    JAW10038.1    AAAB01008960    EAA11956.4    APCN01004377    KK853243    KDR09452.1    GDHC01015334    JAQ03295.1    LBMM01008690    KMQ88692.1    AXCN02000935    GL443740    EFN61703.1    KK107213    QOIP01000007    EZA55299.1    RLU20576.1    KK855397    PTY22370.1    ACPB03001109    GAHY01001473    JAA76037.1    DQ104699    AAZ43093.2    FJ765738    EFN61704.1    KU179863    AND61388.1    DS232014    EDS31907.1    JXUM01029016    KQ560839    KXJ80664.1    EF589782    ABU88380.2    ODYU01003090    SOQ41405.1    GBHO01022472    JAG21132.1    BC154982    BC169586    BC169588    CM004476    AAI54983.1    AAI69586.1    OCT75824.1    EF589781    ABU88379.2    KQ971323    KYB28573.1    GEBQ01031843    JAT08134.1    GBHO01022474    GBHO01022473    GBHO01022471    GBHO01003884    JAG21130.1    JAG21131.1    JAG21133.1    JAG39720.1    GECZ01027718    GECZ01021024    GECZ01020517    GECZ01014025    JAS42051.1    JAS48745.1    JAS49252.1    JAS55744.1    KQ414646    KOC66387.1    KZ288242    PBC31235.1    AK402751    BAM19365.1    GGFL01014210    MBW78388.1    AXCM01004374    GEDC01021480    JAS15818.1    AAZX01001204    NWSH01000086    PCG79770.1    KXJ80663.1    GDHC01008170    JAQ10459.1   

Proteomes

UP000218220    UP000053240    UP000053268    UP000007151    UP000005204    UP000245037    + More
UP000037510    UP000235965    UP000027135    UP000007755    UP000078542    UP000075809    UP000078492    UP000019118    UP000030742    UP000078541    UP000005205    UP000078540    UP000008820    UP000053105    UP000075903    UP000075884    UP000076408    UP000002358    UP000007062    UP000075840    UP000075882    UP000076407    UP000075885    UP000036403    UP000075886    UP000000311    UP000053097    UP000279307    UP000015103    UP000075902    UP000005203    UP000002320    UP000069940    UP000249989    UP000186698    UP000007266    UP000053825    UP000242457    UP000075880    UP000075883   

PRIDE

H9J0S5   

Pfam

PF00450   Peptidase_S10        + More
PF02990   EMP70

Interpro

IPR029058   AB_hydrolase        + More
IPR018202   Ser_caboxypep_ser_AS       
IPR033124   Ser_caboxypep_his_AS       
IPR001563   Peptidase_S10       
IPR004240   EMP70       

SUPFAM

SSF53474   SSF53474       

Gene 3D

3.40.50.1820    

ProteinModelPortal

A0A2A4K0D9   A0A0N1INC9   A0A194PNP2   A0A2A4K0P1   A0A2H1V3X3   A0A2H1V3Z0   + More
A0A212EN12   H9J0S5   A0A2A4JZQ9   A0A2P8YUZ9   R4V3H3   A0A2H1V444   A0A0L7KXC5   A0A146L8K2   A0A146M3S2   A0A1V1G5G1   A0A2J7RMM3   A0A220K8I1   A0A067RMV2   A0A0A9W0I2   A0A0A9X8H2   A0A0K8SL40   A0A0A9XDE9   A0A146L5J6   A0A1B6DAZ8   A0A2H1WQ98   A0A173FDK2   A0A1B6EFH6   A0A1B6G2E3   A0A1B6DKD2   F4X0L6   A0A195D1V5   A0A151WYN0   A0A195D9Z9   N6SSG5   A0A0L7LM79   E9IJU5   A0A195F7F6   A0A158ND03   A0A195B917   A0A1E1WAZ3   A0A336M1Q6   U4U2S4   A0A348G5Z8   A0A146LHK7   Q175U3   A0A0M8ZQT3   A0A182VDU4   A0A146L0Y9   A0A182NMB9   A0A182Y0S5   K7IV06   A0A170XJP7   A0A224XJN6   Q7Q789   A0A182HM77   A0A182LJS3   A0A182XCU7   A0A067QKM7   A0A146L6S5   A0A182PVV1   A0A0J7KEF9   A0A182QCW5   E2AY00   A0A026WJK0   A0A2R7WTA9   R4FLC5   A0A182UCJ9   A0A182TLN9   Q101N9   C9WMM5   E2AY01   A0A182BVG3   B0WNR6   A0A182H8I5   B3SNT5   A0A2H1VKQ6   A0A0A9XKA6   A8WH57   B3SNT4   D7EHX7   A0A1B6KAA3   A0A0A9XV56   A0A1B6FEW7   A0A0L7R680   A0A2A3EHH5   I4DN75   A0A182JGG1   A0A2M4DMN0   A0A182LU18   A0A1B6CQY1   K7IV07   A0A2A4K7Y2   A0A182H8I4   A0A146LT64  

PDB

4MWT     E-value=2.60693e-29,     Score=322

KEGG

101739471    K09645 vitellogenic carboxypeptidase-like protein [EC:3.4.16.-] | (RefSeq) venom serine carboxypepti

GO

GO:0016021   GO:0004185   GO:0051603   GO:0005576   GO:0006508   GO:0016788   GO:0003697   GO:0004519   GO:0005634   GO:0006289   GO:0004518   GO:0006281   GO:0048384  

PANTHER

PTHR11802   PTHR10766  

Subcellular location

Secreted  

SignalP

Position:   1 - 17,         Likelihood:  0.985720

 

 

Length:

505

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0653

Exp number, first 60 AAs:

0.05206

Total prob of N-in:

0.00274

outside

1  -  505

 

 

Pi

13.170839

Theta

18.818204

Tajima's D

-1.052241

CLR

12.717734

CSRT

0.127393630318484

Interpretation

Uncertain