Gene

KWMTBOMO02215

Annotation

reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr4(+):13993252-13995656      View in EpiBrowser

Full name

Probable RNA-directed DNA polymerase from transposon BS      

Alternative Name

Reverse transcriptase

Location in the cell

Nuclear   Reliability : 2.21

CDS

ATGAAGCTCGGTCGCGCTCCCGATTCCGTTCCCGTCACGAGGACTGTGGTGGATTGGCACACGCTGGGCATCAGCCTGGCTGAATCTGATCCACCATCGCTCCCGTTTAACCCGGACTCTATCCCGTCTCCTCAGGATACCGCTGAAGCCATAGACATCTTAACGTCACACATCACCTCGACATTAGATAGGTCATCGAAACAAGTTGTAGCGGAGGACTTCCTTCACCGCTTCAAATTGTCCGACGATATTAGGGAACTCCTTAGAGCTAAGAACGCCTCGATACGCGCCTACGACAGAAGGACTCGCGCCCTCCCAAAGGTCTTACTACCGCTTAGCTCGTACTCTCAAATCGGATACGGTAGTAACTATGCCCCCCTCGTAGGCCCCTCAGGCCGACTCGCGGCGTTCGATGATGACGAAAAAGCAGAGCTGCTGGCCGATACATTGCAAACCCAGTGCACGCCCAGCACTCAATCCGTGGACCCTGTTCATGTAGAATTAGTAGACAGTGAGGTAGAACGCAGAGCCTCCTTGCCACCCTCTGATGCGTTACCACCCGTCACCCCGATGGAAGTTAAAGACTTGATCAAAGACCTACGTCCTCGCAAGGCTCCCGGTTCCGACGGTATATCCAACCGCGTTATTAAACTTCTACCCGTCCAACTCATCGTGATGTTGGCATCTATTTTCAATGCCGCTATGGCGAACTGTATCTTTCCCGCGGTGTGGAAAGAAGCGGACGTTATCGGCATACATAAACCCGGTAAACCAAAAAATCATCCGACGAGCTACCGCCCGATTAGCCTCCTCATGTCTCTAGGCAAACTGTATGAGCGTCTGCTCTACAAACGCCTCAGAGACTTCGTCTCATCCAAGGGCATTCTTATCGATGAACAATTCGGATTCCGTACAAATCACTCATGCGTTCAACAGGTGCACCGCCTCACGGAGCACATTCTTGTGGGGCTTAATCGACCAAAACCGTTATACACGGGAGCTCTCTTCTTCGACGTCGCAAAAGCGTTCGACAAAGTCTGGCACAATGGTTTGATTTTCAAACTATTCAACATGGGCGTGCCGGATAGTCTCGTGCTCATCATACGGGACTTCTTGTCGAACCGCTCTTTTCGATATCGAGTCGAGGGAACCCGCTCCTCCCCACGACCTCTCACAGCTGGAGTCCCGCAAGGCTCTGTCCTCTCACCCCTCCTATTTAGCTTATTCGTCAACGATATTCCCCGGTCGCCGCCGACCCACTTAGCTTTATTCGCCGACGACACGACTGTTTACTATTCTAGTAGAAATAAGTCCCTAATCGCGAAGAAGCTTCAGAGCGCAGCCCTAGCCCTAGGACAGTGGTTCCGAAAATGGCGCATAGACATCAACCCAGCGAAAAGTACTGCGGTGCTATTTCAGAGGGGAAGCTCCACACGGATTTCCTCCCGGATTAGGAGGAGGAATCTCACACCCCCGATTACTCTCTTTAGTCAATCCATACCCTGGGCCAGGAAGGTCAAGTACCTGGGCGTTACCCTGGATGCATCGATGACATTCCGCCCGCATATAAAATCAGTCCGTGACCGTGCCGCGTTTATTCTCGGTAGACTCTACCCCATGATCTGTAAGCGGAGTAAAATGTCCCTTCGGAACAAGGTGACACTTTACAAAACTTGCATAAGGCCCGTCATGACTTACGCGAGTGTGGTGTTCGCTCACGCGGCCCGCACACACATAGACACCCTCCAATCGCTACAATCCCGCTTTTGCAGGTTAGCTGTCGGGGCTCCGTGGTTCGTGAGGAACGTTGACCTACACGACGACCTGGGCCTCGAATCAATTCGGAAATACATGAAGTCAGCGTCGGAACGATACTTCGATAAGGCTATGCGTCATGATAATCGCCTTATCGTTGCCGCCGCTGACTACTCCCCGAATCCTGATCATGCAGGAGCCAGTCACCGTCGACGCCCTAGACACGTCCTTACGGATCCATCAGATCCAATAACCTTTGCATTAGATGCCTTCAGCTCTAATACTAGGGGCAGGCTTAGGGACCCCGGTAACCGTACTCGTCGAACTCGACAAAGAGGTCGACGTGCAACCTAA

Protein

MKLGRAPDSVPVTRTVVDWHTLGISLAESDPPSLPFNPDSIPSPQDTAEAIDILTSHITSTLDRSSKQVVAEDFLHRFKLSDDIRELLRAKNASIRAYDRRTRALPKVLLPLSSYSQIGYGSNYAPLVGPSGRLAAFDDDEKAELLADTLQTQCTPSTQSVDPVHVELVDSEVERRASLPPSDALPPVTPMEVKDLIKDLRPRKAPGSDGISNRVIKLLPVQLIVMLASIFNAAMANCIFPAVWKEADVIGIHKPGKPKNHPTSYRPISLLMSLGKLYERLLYKRLRDFVSSKGILIDEQFGFRTNHSCVQQVHRLTEHILVGLNRPKPLYTGALFFDVAKAFDKVWHNGLIFKLFNMGVPDSLVLIIRDFLSNRSFRYRVEGTRSSPRPLTAGVPQGSVLSPLLFSLFVNDIPRSPPTHLALFADDTTVYYSSRNKSLIAKKLQSAALALGQWFRKWRIDINPAKSTAVLFQRGSSTRISSRIRRRNLTPPITLFSQSIPWARKVKYLGVTLDASMTFRPHIKSVRDRAAFILGRLYPMICKRSKMSLRNKVTLYKTCIRPVMTYASVVFAHAARTHIDTLQSLQSRFCRLAVGAPWFVRNVDLHDDLGLESIRKYMKSASERYFDKAMRHDNRLIVAAADYSPNPDHAGASHRRRPRHVLTDPSDPITFALDAFSSNTRGRLRDPGNRTRRTRQRGRRAT

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  Probable RNA-directed DNA polymerase from transposon BS

Uniprot

Q93137   Q9XXW0   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
V5GNF3   A0A139WA11   V5GNJ2   J9KKL3   X1WLB2   X1WWC4   A0A2S2QEE0   A0A2S2Q352   A0A2S2PX53   A0A2S2N814   A0A1Y1M7E9   A0A023EYS8   J9KC83   A0A2S2NGV8   A0A2H8U0H5   A0A023F6S4   A0A2J7R7D0   J9KCZ4   A0A2J7Q059   A0A2S2RAN7   J9LC15   A0A2J7QUJ9   A0A069DZC5   A0A2J7R4B7   A0A2A4K8E7   A0A2J7RIW7   A0A2J7PMP6   A0A2J7RM10   A0A069DW01   A0A2J7Q4F7   K7IN67   A0A1Y1LKN6   A0A2J7R8R8   A0A2J7RS81   A0A2J7RB54   X1WTA1   A0A2J7RL12   X1WZH0   Q95SX7   A0A2J7RPU2   X1WNI2   A0A2J7PDM0   A0A224XF24   A0A2J7PU96   X1WN18   A0A2J7QFL0   A0A2J7R2E1   A0A2J7RKP3   A0A2J7PMP9   A0A2J7RS77   A0A2J7Q627   A0A2J7Q0Q6   A0A2J7QPI2   A0A2J7R6U1   A0A2J7R579   A0A2A4K918   J9LC21   A0A2J7QR37   A0A2J7R4B1   A0A224XB44   A0A2S2PBB4   A0A0A9YJ00   A0A2S2Q383   A0A2J7PVX3   A0A2J7Q1Y9   A0A0J7K4E0   A0A023F754   A0A2J7Q2R1   A0A2S2R9D4   A0A023F7D1   A0A2J7PBY3   A0A2J7QY69   A0A2J7PQB5   Q07995  

EC Number

2.7.7.49

Pubmed

10333566    26354079    10380107    28004739    18362917    19820115    + More
25474469    26334808    20075255    7753626    12537569    25401762    8387152   

EMBL

U07847    AAA17752.1    AB018558    BAA76304.1    AB055391    BAB21761.1    + More
KQ459265    KPJ02064.1    AF081103    AAC72921.1    GEZM01008457    JAV94772.1    GALX01005359    JAB63107.1    KQ971729    KYB24751.1    GALX01005299    JAB63167.1    ABLF02029306    ABLF02029314    ABLF02060138    ABLF02042518    ABLF02057746    ABLF02003961    ABLF02059872    GGMS01006359    MBY75562.1    GGMS01002955    MBY72158.1    GGMS01000737    MBY69940.1    GGMR01000676    MBY13295.1    GEZM01038405    JAV81653.1    GBBI01004395    JAC14317.1    ABLF02033757    GGMR01003407    MBY16026.1    GFXV01007093    MBW18898.1    GBBI01001646    JAC17066.1    NEVH01006736    PNF36716.1    ABLF02008463    NEVH01020071    PNF21969.1    GGMS01017914    MBY87117.1    ABLF02020655    ABLF02039168    ABLF02061060    NEVH01010546    PNF32261.1    GBGD01000880    JAC88009.1    NEVH01007443    PNF35684.1    NWSH01000032    PCG80497.1    NEVH01003017    PNF40781.1    NEVH01023962    PNF17612.1    NEVH01021586    NEVH01006600    NEVH01002584    PNF19589.1    PNF37419.1    PNF41868.1    GBGD01000799    JAC88090.1    NEVH01018383    PNF23463.1    GEZM01053022    JAV74219.1    NEVH01006721    PNF37225.1    NEVH01000269    PNF43694.1    NEVH01005938    PNF38077.1    ABLF02037660    NEVH01002704    PNF41489.1    ABLF02034467    AY060438    AAL25477.1    NEVH01001355    PNF42855.1    ABLF02008153    ABLF02008462    ABLF02008464    NEVH01026386    PNF14434.1    GFTR01008038    JAW08388.1    NEVH01021205    PNF19912.1    ABLF02021177    ABLF02027367    ABLF02066338    NEVH01014858    PNF27387.1    NEVH01007838    PNF34986.1    NEVH01002716    PNF41415.1    NEVH01023961    PNF17613.1    NEVH01000280    PNF43672.1    NEVH01017542    PNF24034.1    NEVH01019964    PNF22161.1    NEVH01012089    PNF30491.1    NEVH01006754    PNF36554.1    NEVH01007393    PNF35987.1    PCG80496.1    ABLF02036316    ABLF02036319    ABLF02048663    ABLF02066977    NEVH01011985    PNF31054.1    NEVH01007578    PNF35646.1    GFTR01008262    JAW08164.1    GGMR01014053    MBY26672.1    GBHO01010547    GBHO01010546    JAG33057.1    JAG33058.1    GGMS01002992    MBY72195.1    NEVH01020940    PNF20481.1    NEVH01019376    PNF22596.1    LBMM01014395    KMQ85192.1    GBBI01001642    JAC17070.1    NEVH01019080    PNF22876.1    GGMS01017365    MBY86568.1    GBBI01001570    JAC17142.1    NEVH01027074    PNF13841.1    NEVH01009134    PNF33528.1    NEVH01022639    PNF18527.1    S59870    AAB26437.2   

Proteomes

UP000053268    UP000007266    UP000007819    UP000235965    UP000218220    UP000002358    + More
UP000036403   

PRIDE

Q93137    Q9XXW0    Q9BPQ0    Q95SX7   

Pfam

PF00078   RVT_1        + More
PF14529   Exo_endo_phos_2
PF03372   Exo_endo_phos
PF07530   PRE_C2HC

Interpro

IPR036691   Endo/exonu/phosph_ase_sf        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR000477   RT_dom       
IPR006579   Pre_C2HC_dom       

SUPFAM

SSF56219   SSF56219       

Gene 3D

3.60.10.10    

ProteinModelPortal

Q93137   Q9XXW0   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
V5GNF3   A0A139WA11   V5GNJ2   J9KKL3   X1WLB2   X1WWC4   A0A2S2QEE0   A0A2S2Q352   A0A2S2PX53   A0A2S2N814   A0A1Y1M7E9   A0A023EYS8   J9KC83   A0A2S2NGV8   A0A2H8U0H5   A0A023F6S4   A0A2J7R7D0   J9KCZ4   A0A2J7Q059   A0A2S2RAN7   J9LC15   A0A2J7QUJ9   A0A069DZC5   A0A2J7R4B7   A0A2A4K8E7   A0A2J7RIW7   A0A2J7PMP6   A0A2J7RM10   A0A069DW01   A0A2J7Q4F7   K7IN67   A0A1Y1LKN6   A0A2J7R8R8   A0A2J7RS81   A0A2J7RB54   X1WTA1   A0A2J7RL12   X1WZH0   Q95SX7   A0A2J7RPU2   X1WNI2   A0A2J7PDM0   A0A224XF24   A0A2J7PU96   X1WN18   A0A2J7QFL0   A0A2J7R2E1   A0A2J7RKP3   A0A2J7PMP9   A0A2J7RS77   A0A2J7Q627   A0A2J7Q0Q6   A0A2J7QPI2   A0A2J7R6U1   A0A2J7R579   A0A2A4K918   J9LC21   A0A2J7QR37   A0A2J7R4B1   A0A224XB44   A0A2S2PBB4   A0A0A9YJ00   A0A2S2Q383   A0A2J7PVX3   A0A2J7Q1Y9   A0A0J7K4E0   A0A023F754   A0A2J7Q2R1   A0A2S2R9D4   A0A023F7D1   A0A2J7PBY3   A0A2J7QY69   A0A2J7PQB5   Q07995  

KEGG

105842121    no KO assigned | (RefSeq) uncharacterized LOC105842121

GO

GO:0003964   GO:0004519   GO:0006313  

Length:

702

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

3.46034000000001

Exp number, first 60 AAs:

0

Total prob of N-in:

0.06237

outside

1  -  702

 

 

Pi

0

Theta

0

Tajima's D

0

CLR

0.004134

CSRT

0

Interpretation

Uncertain