Gene

KWMTBOMO02089  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA003183

Annotation

PREDICTED:_OTU_domain-containing_protein_6B_[Plutella_xylostella]

Location

Bomo_Chr4(-):11874815-11876007      View in EpiBrowser

Full name

Deubiquitinase OTUD6B      

Location in the cell

Nuclear   Reliability : 3.99

CDS

ATGGAAACGGAGAAAGAAGCAGAAGATGTAAATAGTATGGAAATTAGACAACGTAAGGAGAAAAAAGAGTTGCAAGCCCAAATTCAAGCATTGAAAAAAGTAGCTAAAAATGACAAAACAAAAAAGAAAGATCTTGCTGCTGAAATATCAAGGCTTGAAAGTGAATTAGAAATTAGACACAATAAGGAGATTATGGAAGCAAAACTTTCTTCTGAACACAACTTAGAACCAATGGTAGATGAAACAAGAGTTATCAAAACAAAAGTATCTAAAGCGCAACGGCGCCGAGATAAAAAATCAGAACAAGAGAAAATCCGCGAAGAAGAAATAAAACTTCAAGACAAGGAAAATGTTCATGGAGCTAGGAACATTGAAATACAAACTATTACCAAAAGGCTTGAAGAAAAAAATTTGAAAATTTTTACTGTTCCATCAGATGGAGATTGTTTATACAAAGCTGTAAGTCATCAGTTGCAACTTGTGAAACAAGAGACTGTAAGCGTGGATGAATTGAGAGAAAAAGTTTCAAATTACATAAGGGATAACAAAGATGATTTCAAACCTTTCATGTGTAACCCAGAAACACTAGAAACATTAACAGATGAGGAATTTGAAGATTATTGTCATAAAATAATGAATACCAAAGATTGGGGTGGTCAATTAGAACTTAGAGCCTTGTCAAATATTTTAAAGTGTCCGATAAATGTGATACAAGCTGTCGGACCTGATTGTATAGAGCAAGGCACAGAATTTGAAGGCCCACCATTGATAATCACATATCACAGGCACATGTATAGCTTAGGTGAACATTATAATTCAACCAATCTGATTTCAGTTAGTGAGAATACCTCATAA

Protein

METEKEAEDVNSMEIRQRKEKKELQAQIQALKKVAKNDKTKKKDLAAEISRLESELEIRHNKEIMEAKLSSEHNLEPMVDETRVIKTKVSKAQRRRDKKSEQEKIREEEIKLQDKENVHGARNIEIQTITKRLEEKNLKIFTVPSDGDCLYKAVSHQLQLVKQETVSVDELREKVSNYIRDNKDDFKPFMCNPETLETLTDEEFEDYCHKIMNTKDWGGQLELRALSNILKCPINVIQAVGPDCIEQGTEFEGPPLIITYHRHMYSLGEHYNSTNLISVSENTS

Description

Deubiquitinating enzyme that may play a role in the ubiquitin-dependent regulation of different cellular processes.

Catalytic Activity

Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).

Keywords

Hydrolase   Protease   Thiol protease   Ubl conjugation pathway   Complete proteome   Reference proteome  

Feature

chain  Deubiquitinase OTUD6B

Uniprot

H9J0Z6   A0A2A4JIS7   A0A2W1BUE7   A0A2H1W0V6   A0A212EN17   A0A0L7LC18   + More
A0A194Q5M7   A0A194QLQ7   J3JVS5   A0A1I8P3I4   A0A0L0C5A7   A0A0K8TM04   A0A1Y1KC55   A0A1B6EJC5   A0A1B6K759   D6WMI2   T1PA48   W8BNQ3   A0A1I8MK90   A0A0C9QVT3   A0A1A9WGJ7   R4WJ85   A0A2J7RAU7   A0A1W4X5Z3   A0A1A9USW5   A0A154PJH3   A0A034WKK2   A0A1B0G442   A0A170Z9L5   Q17HZ1   A0A1S4F202   D3TKU4   A0A0P4VUE6   A0A1A9ZQH9   A0A0K8UZB1   A0A2R7WH51   B4PCF8   B4ITZ9   A0A0A1XDM3   A0A0K8VGA5   A0A195FJ55   A0A182H7A8   A0A1B6CUT1   Q9VUN9   Q8MRW3   L5M0L8   B4QL19   A0A0C9R507   S7MUG6   A0A226P822   A0A0A9X8U4   A0A1B0GH74   E0VBB0   A0A195DMP8   W5MVR0   A0A158P208   E9ISA5   G1PVS4   A0A026X071   E2BUZ0   A0A2G8K6T4   A0A1S3IVB3   A0A0L8GRC9   A0A226NPW4   B3NI23   F1RXF7   A0A067R069   T1ICX6   L5KBD7   A0A0Q3MFB4   A0A195AWE1   B4IZ10   E2B273   F4W682   B0X9B4   A0A0N1ITD0   A0A1Q3F987   A0A1B0DJU3   B4L149   A0A2S2QVN3   E3TCR8   A0A3M0KQ13   A0A1S3EUB1   A0A088ACL2   Q6GM06   Q5ZIP6   A0A0L7QYU1   A0A151IKL1   A0A0J7L6D4   A0A1V4KGW8   F1N0N7   W4YP90   A0A1S3EUA0   E3TE61   G3T6N1   K1PQW3   A0A2M4CUQ4   W5PJW3   A0A2I2V2I5   A0A3L8T1B8  

EC Number

3.4.19.12

Pubmed

19121390    28756777    22118469    26227816    26354079    22516182    + More
23537049    26108605    26369729    28004739    18362917    19820115    24495485    25315136    23691247    25348373    17510324    20353571    27129103    17994087    17550304    25830018    26483478    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    22936249    24621616    25401762    26823975    20566863    21347285    21282665    21993624    24508170    30249741    20798317    29023486    30723633    24845553    23258410    21719571    20634964    15642098    19393038    23127152    22992520    20809919    17975172    30282656   

EMBL

BABH01010489    NWSH01001239    PCG72005.1    KZ149933    PZC77285.1    ODYU01005642    + More
SOQ46698.1    AGBW02013744    OWR42890.1    JTDY01001740    KOB73033.1    KQ459583    KPI98700.1    KQ461196    KPJ06462.1    APGK01029294    BT127343    KB740731    KB632226    AEE62305.1    ENN79291.1    ERL90305.1    JRES01000902    KNC27422.1    GDAI01002638    JAI14965.1    GEZM01088760    JAV57971.1    GECZ01031755    JAS38014.1    GECU01000414    JAT07293.1    KQ971343    EFA04273.1    KA645564    AFP60193.1    GAMC01015189    GAMC01015186    JAB91369.1    GBYB01007854    JAG77621.1    AK417545    BAN20760.1    NEVH01006564    PNF37960.1    KQ434936    KZC11963.1    GAKP01004660    GAKP01004659    JAC54293.1    CCAG010006632    GEMB01002462    JAS00724.1    CH477244    EAT46285.1    EZ422031    ADD18454.1    GDKW01000431    JAI56164.1    GDHF01020378    JAI31936.1    KK854815    PTY18984.1    CM000159    EDW94868.1    CH891752    EDW99862.1    GBXI01005230    JAD09062.1    GDHF01014398    JAI37916.1    KQ981523    KYN40438.1    JXUM01115898    KQ565926    KXJ70527.1    GEDC01020120    JAS17178.1    AE014296    BT044439    AAF49636.1    ACH92504.1    AY119232    AAM51092.1    KB105545    ELK32219.1    CM000363    CM002912    EDX10544.1    KMY99743.1    GBYB01007852    JAG77619.1    KE162369    EPQ07954.1    AWGT02000132    OXB75868.1    GBHO01027553    GBRD01006803    GDHC01008411    GDHC01005084    JAG16051.1    JAG59018.1    JAQ10218.1    JAQ13545.1    AJWK01004019    DS235023    EEB10666.1    KQ980724    KYN14106.1    AHAT01004683    ADTU01006930    GL765324    EFZ16531.1    AAPE02026207    KK107051    QOIP01000010    EZA61652.1    RLU17687.1    GL450772    EFN80527.1    MRZV01000830    PIK43718.1    KQ420777    KOF79389.1    MCFN01000001    OXB69387.1    CH954178    EDV52109.1    AEMK02000022    DQIR01258057    HDC13535.1    KK852804    KDR16240.1    ACPB03003012    KB030886    ELK08672.1    LMAW01002490    KQK81048.1    KQ976731    KYM76284.1    CH916366    EDV97718.1    GL445067    EFN60199.1    GL887707    EGI70217.1    DS232529    EDS43046.1    KQ435840    KOX71408.1    GFDL01010958    JAV24087.1    AJVK01001081    CH933809    EDW18206.1    GGMS01011979    MBY81182.1    GU588148    ADO28104.1    QRBI01000104    RMC15176.1    BC074286    AJ720738    KQ414685    KOC63799.1    KQ977199    KYN05008.1    LBMM01000494    KMQ98211.1    LSYS01003169    OPJ83645.1    AAGJ04099044    GU588641    ADO28597.1    JH818980    EKC18810.1    GGFL01004817    MBW68995.1    AMGL01112918    AMGL01112919    AANG04003518    QUSF01000001    RLW13122.1   

Proteomes

UP000005204    UP000218220    UP000007151    UP000037510    UP000053268    UP000053240    + More
UP000019118    UP000030742    UP000095300    UP000037069    UP000007266    UP000095301    UP000091820    UP000235965    UP000192223    UP000078200    UP000076502    UP000092444    UP000008820    UP000092445    UP000002282    UP000078541    UP000069940    UP000249989    UP000000803    UP000000304    UP000198419    UP000092461    UP000009046    UP000078492    UP000018468    UP000005205    UP000001074    UP000053097    UP000279307    UP000008237    UP000230750    UP000085678    UP000053454    UP000198323    UP000008711    UP000008227    UP000027135    UP000015103    UP000010552    UP000051836    UP000078540    UP000001070    UP000000311    UP000007755    UP000002320    UP000053105    UP000092462    UP000009192    UP000269221    UP000081671    UP000005203    UP000000539    UP000053825    UP000078542    UP000036403    UP000190648    UP000009136    UP000007110    UP000221080    UP000007646    UP000005408    UP000002356    UP000011712    UP000276834   

PRIDE

H9J0Z6    Q9VUN9    Q8MRW3    F1RXF7   

Pfam

PF02338   OTU

Interpro

IPR038765   Papain-like_cys_pep_sf        + More
IPR003323   OTU_dom       

SUPFAM

SSF54001   SSF54001       

ProteinModelPortal

H9J0Z6   A0A2A4JIS7   A0A2W1BUE7   A0A2H1W0V6   A0A212EN17   A0A0L7LC18   + More
A0A194Q5M7   A0A194QLQ7   J3JVS5   A0A1I8P3I4   A0A0L0C5A7   A0A0K8TM04   A0A1Y1KC55   A0A1B6EJC5   A0A1B6K759   D6WMI2   T1PA48   W8BNQ3   A0A1I8MK90   A0A0C9QVT3   A0A1A9WGJ7   R4WJ85   A0A2J7RAU7   A0A1W4X5Z3   A0A1A9USW5   A0A154PJH3   A0A034WKK2   A0A1B0G442   A0A170Z9L5   Q17HZ1   A0A1S4F202   D3TKU4   A0A0P4VUE6   A0A1A9ZQH9   A0A0K8UZB1   A0A2R7WH51   B4PCF8   B4ITZ9   A0A0A1XDM3   A0A0K8VGA5   A0A195FJ55   A0A182H7A8   A0A1B6CUT1   Q9VUN9   Q8MRW3   L5M0L8   B4QL19   A0A0C9R507   S7MUG6   A0A226P822   A0A0A9X8U4   A0A1B0GH74   E0VBB0   A0A195DMP8   W5MVR0   A0A158P208   E9ISA5   G1PVS4   A0A026X071   E2BUZ0   A0A2G8K6T4   A0A1S3IVB3   A0A0L8GRC9   A0A226NPW4   B3NI23   F1RXF7   A0A067R069   T1ICX6   L5KBD7   A0A0Q3MFB4   A0A195AWE1   B4IZ10   E2B273   F4W682   B0X9B4   A0A0N1ITD0   A0A1Q3F987   A0A1B0DJU3   B4L149   A0A2S2QVN3   E3TCR8   A0A3M0KQ13   A0A1S3EUB1   A0A088ACL2   Q6GM06   Q5ZIP6   A0A0L7QYU1   A0A151IKL1   A0A0J7L6D4   A0A1V4KGW8   F1N0N7   W4YP90   A0A1S3EUA0   E3TE61   G3T6N1   K1PQW3   A0A2M4CUQ4   W5PJW3   A0A2I2V2I5   A0A3L8T1B8  

PDB

4BOP     E-value=0.000528366,     Score=101

KEGG

101740742    K18342 OTU domain-containing protein 6 [EC:3.4.19.12] | (RefSeq) OTU domain-containing protein 6B

GO

GO:0008233   GO:0004843   GO:0016579   GO:0016021   GO:0036459  

Length:

284

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0

Exp number, first 60 AAs:

0

Total prob of N-in:

0.04795

outside

1  -  284

 

 

Pi

132.768475

Theta

123.237299

Tajima's D

0.126094

CLR

0.208409

CSRT

0.407629618519074

Interpretation

Possibly Positive selection