Gene

KWMTBOMO02053  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA002967

Annotation

hydroxyacyl-coenzyme_A_dehydrogenase_[Bombyx_mori]

Location

Bomo_Chr4(+):11116587-11126929      View in EpiBrowser

Location in the cell

Mitochondrial   Reliability : 3.021

CDS

ATGGCGAATAGCAAAATATTAAGTGCCCTTAAGATCTTGAGAAGCCGTAAGGAATTATTCATATCCGGTGTACATAGCCGAAAGTATGCCGTTCCAGCAAGCCAAGTACATACAAAATGCAAATTGGTCAATGGAGTTTACGTAGTCACTTTGGACTCTCCAAATGTTAAAGTAAACTCACTTAACACCCAAGTGATGGAAGAAGTTAGTAACATCGTAAATGAAATTGAAACAAATTCTGGTATTGAAGCTGCAGTCATTATATCAGGCAAGCCTGGATGCTTCATTGCAGGGGCTGATATAAGCATGATCGAAAACTGCAAAACAAAGGAAGAAGTTGTCAGTCTGTCTAAAAGAGGACATGAAATATTCAGAAGAATCGAACAATCACGGAAACCGTATATTGCCGCAATACAAGGCAGCTGTCTAGGAGGTGGATTAGAGACTGCTCTTGCATGTAAATATCGCATTGCTGTGAAAGACTCCAAAACAGGATTTGGACTACCAGAAGTCATGTTGGGACTTTTGCCCGGCGGTGGAGGGACACAGAGATTACCTGCTCTCACCTCCATACCTACAACTTTGGACCTAGCTCTAACTGGTAAAACTGTGAAAGCTGATAAAGCAAAGAAATTGGGAATTGTAGATCTGTTAGTTTCCCCTCTTGGACCAGGTTTGGGTCAGCCTGAGGAAAATACAGCCAAATACCTCGAAACTGTAGCTATACAGATTGCAAAGGATATAGCTGCTGGAAAAATAATTGTTGATAGATCGAAAAAAGGCCTAGTACAGAAGATTACTGCAATCGTAATGCAATGGGAGTTTGTGAAAAACATCATATTTAAGAAAGCCAAGGAACAAGTAATGAAAGCATCACGTGGACTCTACCCTGCCCCTCTGAAAATACTTGAAGTAGTAAGAACAGGAGTGGACAAGGGTCCTGTAGCCGGTTATGAAGCAGAAGCACAAGGCTTTGGTGAACTGGCTATGACTCCTCAGAGCAAAGGGTTGATTGGTTTATTCCGTGGACAAACAGAATGTAAGAAGAATAGGTTCGGAAAATCCCAAGTTGATGTAAAAACGATTGGTGTTCTTGGTGCCGGTTTGATGGGAGCAGGTATAGTGCAAGTGTCAATCGACAAAGGCTACAATGTCGTAATGAAAGACGCCACTAATGCAGGCTTGTATCGCGGCGTTGGACAAATTCAAACCGGACTAAGTAATGCTGTGAAACGCAAAAGAATTTCATCTCTACAAAAGGATAAGTACTTATCGAATCTACTTCCTACATTGGACTATGCCAAGTTCAAAAATGCGGATTGTGTAATTGAAGCCGTTTTCGAGGATATTAACATCAAGCACAAAGTTATCAAAGAGTTAGAGGCTGTAGTGCCGAAACATTGTATTATAGCTACAAACACTAGTGCTATACCTATTACAAAAATCGCAGCTGGCAGCAGTCGTCCTGATAAAGTAATTGGCATGCATTACTTCTCACCAGTTGACAAGATGCAATTGCTAGAAATTATTAAGCACCCCGGCACCAGCGACGATACATCGGCAGCCGCTGTGGCCGTAGGTCTACGACAAGGAAAGGTCGTCATCACGGTGGGGGATGGGCCTGGTTTTTACACCACACGTATCCTTTCTACTATGCTTAGTGAAGCAGTAAGACTGCTACAAGAGGGTGTTGATCCTAAAGAACTGGATAACATGACAAAGCAATTTGGTTTCCCTGTCGGCGCTGCTACATTGGCTGACGAAGTTGGTATCGATGTCGGCTCTCACATCGCTGTGGATCTAGCCAAGGCCTTTGGTGATCGCATTAGCGGAGGAAACTTGGGTATCATGCAGGACTTAGTGCAAGCTGGATACATGGGACGCAAGTCCGGCAAAGGTTTCTATGTGTATGAAAAAGGCTCTAAAAACAGGGAAGTAAACCATGGTGCTATTAAAATCCTGAAAGACAAGTATGCATTAGAACCTCGTGGTGCTAATACTGTTGAAGACCAACAACTGCGAATGGTTTCCAGATTTGTAAATGAAGCAGTGTTATCATTGGAAGAAAAAATTCTACACAACCCCCTTGAAGGTGATGTTGGTGCGGTCTTTGGTCTCGGCTTCCCTCCATTTACTGGTGGACCTTTCAGATGGGTGGATCAATATGGCGCTGATAAATTAGTAAAGAAAATGGAGGAATACCAGGGTCTTTATGGCGCTCCATTCAAACCAGCTCAAACCCTTGTAGATATGGCCAAAGACACAAGTAAAAAATTCTATAAGAACTGA

Protein

MANSKILSALKILRSRKELFISGVHSRKYAVPASQVHTKCKLVNGVYVVTLDSPNVKVNSLNTQVMEEVSNIVNEIETNSGIEAAVIISGKPGCFIAGADISMIENCKTKEEVVSLSKRGHEIFRRIEQSRKPYIAAIQGSCLGGGLETALACKYRIAVKDSKTGFGLPEVMLGLLPGGGGTQRLPALTSIPTTLDLALTGKTVKADKAKKLGIVDLLVSPLGPGLGQPEENTAKYLETVAIQIAKDIAAGKIIVDRSKKGLVQKITAIVMQWEFVKNIIFKKAKEQVMKASRGLYPAPLKILEVVRTGVDKGPVAGYEAEAQGFGELAMTPQSKGLIGLFRGQTECKKNRFGKSQVDVKTIGVLGAGLMGAGIVQVSIDKGYNVVMKDATNAGLYRGVGQIQTGLSNAVKRKRISSLQKDKYLSNLLPTLDYAKFKNADCVIEAVFEDINIKHKVIKELEAVVPKHCIIATNTSAIPITKIAAGSSRPDKVIGMHYFSPVDKMQLLEIIKHPGTSDDTSAAAVAVGLRQGKVVITVGDGPGFYTTRILSTMLSEAVRLLQEGVDPKELDNMTKQFGFPVGAATLADEVGIDVGSHIAVDLAKAFGDRISGGNLGIMQDLVQAGYMGRKSGKGFYVYEKGSKNREVNHGAIKILKDKYALEPRGANTVEDQQLRMVSRFVNEAVLSLEEKILHNPLEGDVGAVFGLGFPPFTGGPFRWVDQYGADKLVKKMEEYQGLYGAPFKPAQTLVDMAKDTSKKFYKN

Similarity

Belongs to the enoyl-CoA hydratase/isomerase family.

Uniprot

Q2F686   H9J0D1   A0A194PLY5   A0A068FJG9   A0A212FAS2   A0A2H1WAM2   + More
A0A194QNG0   S4PXY5   A0A182FNA1   A0A2M4BEQ5   A0A2M4BFA5   U5EW00   A0A2M3ZFI0   A0A2M3ZFG6   A0A2M4A1V6   W5JCS5   A0A2M4A1U5   A0A084VI50   A0A182M3A5   A0A182W7P6   A0A182XZN5   A0A182JSD1   A0A182R0N7   Q16TS7   A0A182VD20   B0XLF3   A0A182L2K5   Q7Q3A1   A0A182IEF4   A0A182RU85   A0A182PJP5   A0A182TFW3   A0A182JE28   Q1DGR4   A0A1B0CVB3   A0A182MZA7   T1DQ42   A0A182H6J0   A0A182X1H4   A0A1Q3FDZ4   A0A1L8DYL3   A0A1L8DYI3   A0A3B0KKL1   B4G819   Q29NA3   B4M9G5   B4KH24   B4MTL1   B3MUW0   B3N8F4   B4NY54   Q9V397   A0A1A9YAT6   A0A1A9W002   Q8IPE8   B4HYZ1   A0A1B0B7H6   B4Q7T9   D3TSD9   A0A1B0A4X2   A0A0M4ESC9   A0A1I8MXU8   A0A1W4WA91   T1PFH4   A0A1A9UCN6   A0A1I8P083   A0A0L0C606   B4JCF5   A0A1Y1NJQ7   A0A0T6AT59   A0A336KZW8   A0A1B0FLJ3   N6UKT1   D6WNJ5   A0A232F6Y9   K7IQV3   J3JZ20   A0A182S6H2   E1ZXM8   N6UN62   E2C2R4   A0A026WF63   A0A310SB78   A0A0A1XRE1   A0A1J1IJI3   A0A0M9A3C6   A0A195FVV8   A0A146LFU0   A0A158NLR9   A0A0K8SLU2   A0A0A9Y8J7   A0A0C9RF77   A0A067REB8   A0A195CEJ5   A0A151WN20   A0A1B6DDQ1   A0A195DSE3   A0A069DWP2   A0A224X7Z8   A0A034VAS8  

Pubmed

19121390    26354079    26385554    22118469    23622113    20920257    + More
23761445    24438588    25244985    17510324    20966253    12364791    14747013    17210077    26483478    17994087    15632085    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    22936249    20353571    25315136    26108605    28004739    23537049    18362917    19820115    28648823    20075255    22516182    20798317    24508170    30249741    25830018    26823975    21347285    25401762    24845553    26334808    25348373   

EMBL

DQ311186    ABD36131.1    BABH01010547    BABH01010548    KQ459601    KPI93749.1    + More
KJ622097    AID66687.1    AGBW02009433    OWR50827.1    ODYU01007388    SOQ50103.1    KQ461196    KPJ06510.1    GAIX01004228    JAA88332.1    GGFJ01002356    MBW51497.1    GGFJ01002357    MBW51498.1    GANO01000770    JAB59101.1    GGFM01006565    MBW27316.1    GGFM01006543    MBW27294.1    GGFK01001446    MBW34767.1    ADMH02001533    ETN62152.1    GGFK01001404    MBW34725.1    ATLV01013284    KE524849    KFB37644.1    AXCM01004662    AXCN02002070    CH477641    EAT37915.1    EAT37916.1    DS234448    EDS34040.1    AAAB01008964    EAA12305.4    APCN01005201    CH900762    EAT32343.1    AJWK01030388    GAMD01001400    JAB00191.1    JXUM01114162    JXUM01114163    KQ565759    KXJ70695.1    GFDL01009278    JAV25767.1    GFDF01002560    JAV11524.1    GFDF01002561    JAV11523.1    OUUW01000010    SPP85691.1    CH479180    EDW28499.1    CH379060    EAL33439.2    CH940654    EDW57841.1    CH933807    EDW12235.1    CH963852    EDW75450.1    CH902624    EDV33025.2    CH954177    EDV58377.1    CM000157    EDW88656.1    AF181648    AE014134    AAD55434.1    AAF52789.1    AAN10697.1    CH480818    EDW52271.1    JXJN01009667    CM000361    CM002910    EDX04371.1    KMY89287.1    EZ424341    ADD20617.1    CP012523    ALC40225.1    KA647542    AFP62171.1    JRES01000864    KNC27681.1    CH916368    EDW03109.1    GEZM01001140    JAV98121.1    LJIG01022873    KRT78289.1    UFQS01000186    UFQS01001254    UFQT01000186    UFQT01001254    SSX00923.1    SSX09946.1    SSX21303.1    CCAG010008497    APGK01029294    APGK01029295    KB740731    KB632226    ENN79292.1    ERL90303.1    KQ971343    EFA04382.1    NNAY01000802    OXU26435.1    BT128501    AEE63458.1    GL435067    EFN74066.1    APGK01025474    APGK01025475    KB740591    ENN80162.1    GL452203    EFN77749.1    KK107238    QOIP01000007    EZA54760.1    RLU20785.1    KQ765234    OAD54016.1    GBXI01014555    GBXI01001154    JAC99736.1    JAD13138.1    CVRI01000052    CRK99700.1    KQ435748    KOX76405.1    KQ981219    KYN44447.1    GDHC01011565    JAQ07064.1    ADTU01019758    GBRD01011538    JAG54286.1    GBHO01014212    JAG29392.1    GBYB01011752    JAG81519.1    KK852514    KDR22191.1    KQ977957    KYM98488.1    KQ982919    KYQ49269.1    GEDC01013467    JAS23831.1    KQ980489    KYN15840.1    GBGD01000579    JAC88310.1    GFTR01007950    JAW08476.1    GAKP01018542    GAKP01018541    JAC40411.1   

Proteomes

UP000005204    UP000053268    UP000007151    UP000053240    UP000069272    UP000000673    + More
UP000030765    UP000075883    UP000075920    UP000076408    UP000075881    UP000075886    UP000008820    UP000075903    UP000002320    UP000075882    UP000007062    UP000075840    UP000075900    UP000075885    UP000075902    UP000075880    UP000092461    UP000075884    UP000069940    UP000249989    UP000076407    UP000268350    UP000008744    UP000001819    UP000008792    UP000009192    UP000007798    UP000007801    UP000008711    UP000002282    UP000000803    UP000092443    UP000091820    UP000001292    UP000092460    UP000000304    UP000092445    UP000092553    UP000095301    UP000192221    UP000078200    UP000095300    UP000037069    UP000001070    UP000092444    UP000019118    UP000030742    UP000007266    UP000215335    UP000002358    UP000075901    UP000000311    UP000008237    UP000053097    UP000279307    UP000183832    UP000053105    UP000078541    UP000005205    UP000027135    UP000078542    UP000075809    UP000078492   

PRIDE

Q2F686    H9J0D1    Q9V397    Q8IPE8   

Pfam

PF00725   3HCDH        + More
PF00378   ECH_1
PF02737   3HCDH_N
PF07690   MFS_1
PF14912   THEG

Interpro

IPR029045   ClpP/crotonase-like_dom_sf        + More
IPR006176   3-OHacyl-CoA_DH_NAD-bd       
IPR012803   Fa_ox_alpha_mit       
IPR008927   6-PGluconate_DH-like_C_sf       
IPR006108   3HC_DH_C       
IPR036291   NAD(P)-bd_dom_sf       
IPR001753   Enoyl-CoA_hydra/iso       
IPR018376   Enoyl-CoA_hyd/isom_CS       
IPR036259   MFS_trans_sf       
IPR011701   MFS       
IPR020846   MFS_dom       
IPR006623   THEG       
IPR006180   3-OHacyl-CoA_DH_CS       

SUPFAM

SSF48179   SSF48179        + More
SSF52096   SSF52096       
SSF51735   SSF51735       
SSF103473   SSF103473       

CDD

cd06174  MFS

ProteinModelPortal

Q2F686   H9J0D1   A0A194PLY5   A0A068FJG9   A0A212FAS2   A0A2H1WAM2   + More
A0A194QNG0   S4PXY5   A0A182FNA1   A0A2M4BEQ5   A0A2M4BFA5   U5EW00   A0A2M3ZFI0   A0A2M3ZFG6   A0A2M4A1V6   W5JCS5   A0A2M4A1U5   A0A084VI50   A0A182M3A5   A0A182W7P6   A0A182XZN5   A0A182JSD1   A0A182R0N7   Q16TS7   A0A182VD20   B0XLF3   A0A182L2K5   Q7Q3A1   A0A182IEF4   A0A182RU85   A0A182PJP5   A0A182TFW3   A0A182JE28   Q1DGR4   A0A1B0CVB3   A0A182MZA7   T1DQ42   A0A182H6J0   A0A182X1H4   A0A1Q3FDZ4   A0A1L8DYL3   A0A1L8DYI3   A0A3B0KKL1   B4G819   Q29NA3   B4M9G5   B4KH24   B4MTL1   B3MUW0   B3N8F4   B4NY54   Q9V397   A0A1A9YAT6   A0A1A9W002   Q8IPE8   B4HYZ1   A0A1B0B7H6   B4Q7T9   D3TSD9   A0A1B0A4X2   A0A0M4ESC9   A0A1I8MXU8   A0A1W4WA91   T1PFH4   A0A1A9UCN6   A0A1I8P083   A0A0L0C606   B4JCF5   A0A1Y1NJQ7   A0A0T6AT59   A0A336KZW8   A0A1B0FLJ3   N6UKT1   D6WNJ5   A0A232F6Y9   K7IQV3   J3JZ20   A0A182S6H2   E1ZXM8   N6UN62   E2C2R4   A0A026WF63   A0A310SB78   A0A0A1XRE1   A0A1J1IJI3   A0A0M9A3C6   A0A195FVV8   A0A146LFU0   A0A158NLR9   A0A0K8SLU2   A0A0A9Y8J7   A0A0C9RF77   A0A067REB8   A0A195CEJ5   A0A151WN20   A0A1B6DDQ1   A0A195DSE3   A0A069DWP2   A0A224X7Z8   A0A034VAS8  

PDB

5ZRV     E-value=0,     Score=2066

KEGG

692820    K07515 enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.211] | (R

PATHWAY

00062    Fatty acid elongation - Bombyx mori (domestic silkworm)
00071    Fatty acid degradation - Bombyx mori (domestic silkworm)
00280    Valine, leucine and isoleucine degradation - Bombyx mori (domestic silkworm)
00310    Lysine degradation - Bombyx mori (domestic silkworm)
00380    Tryptophan metabolism - Bombyx mori (domestic silkworm)
00410    beta-Alanine metabolism - Bombyx mori (domestic silkworm)
00640    Propanoate metabolism - Bombyx mori (domestic silkworm)
00650    Butanoate metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
01200    Carbon metabolism - Bombyx mori (domestic silkworm)
01212    Fatty acid metabolism - Bombyx mori (domestic silkworm)

GO

GO:0006635   GO:0004300   GO:0003857   GO:0016507   GO:0055085   GO:0016021   GO:0016509   GO:0005739   GO:0042594   GO:0008340   GO:0042060   GO:0005777   GO:0016853   GO:0016491   GO:0006631   GO:0003824   GO:0008152   GO:0048384   GO:0055114  

Length:

762

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.227390000000001

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00442

outside

1  -  762

 

 

Pi

213.028583

Theta

202.937548

Tajima's D

-2.023671

CLR

0.517831

CSRT

0.0153492325383731

Interpretation

Uncertain