SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO02053  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA002967
Annotation
hydroxyacyl-coenzyme_A_dehydrogenase_[Bombyx_mori]
Location in the cell
Mitochondrial   Reliability : 3.021
 

Sequence

CDS
ATGGCGAATAGCAAAATATTAAGTGCCCTTAAGATCTTGAGAAGCCGTAAGGAATTATTCATATCCGGTGTACATAGCCGAAAGTATGCCGTTCCAGCAAGCCAAGTACATACAAAATGCAAATTGGTCAATGGAGTTTACGTAGTCACTTTGGACTCTCCAAATGTTAAAGTAAACTCACTTAACACCCAAGTGATGGAAGAAGTTAGTAACATCGTAAATGAAATTGAAACAAATTCTGGTATTGAAGCTGCAGTCATTATATCAGGCAAGCCTGGATGCTTCATTGCAGGGGCTGATATAAGCATGATCGAAAACTGCAAAACAAAGGAAGAAGTTGTCAGTCTGTCTAAAAGAGGACATGAAATATTCAGAAGAATCGAACAATCACGGAAACCGTATATTGCCGCAATACAAGGCAGCTGTCTAGGAGGTGGATTAGAGACTGCTCTTGCATGTAAATATCGCATTGCTGTGAAAGACTCCAAAACAGGATTTGGACTACCAGAAGTCATGTTGGGACTTTTGCCCGGCGGTGGAGGGACACAGAGATTACCTGCTCTCACCTCCATACCTACAACTTTGGACCTAGCTCTAACTGGTAAAACTGTGAAAGCTGATAAAGCAAAGAAATTGGGAATTGTAGATCTGTTAGTTTCCCCTCTTGGACCAGGTTTGGGTCAGCCTGAGGAAAATACAGCCAAATACCTCGAAACTGTAGCTATACAGATTGCAAAGGATATAGCTGCTGGAAAAATAATTGTTGATAGATCGAAAAAAGGCCTAGTACAGAAGATTACTGCAATCGTAATGCAATGGGAGTTTGTGAAAAACATCATATTTAAGAAAGCCAAGGAACAAGTAATGAAAGCATCACGTGGACTCTACCCTGCCCCTCTGAAAATACTTGAAGTAGTAAGAACAGGAGTGGACAAGGGTCCTGTAGCCGGTTATGAAGCAGAAGCACAAGGCTTTGGTGAACTGGCTATGACTCCTCAGAGCAAAGGGTTGATTGGTTTATTCCGTGGACAAACAGAATGTAAGAAGAATAGGTTCGGAAAATCCCAAGTTGATGTAAAAACGATTGGTGTTCTTGGTGCCGGTTTGATGGGAGCAGGTATAGTGCAAGTGTCAATCGACAAAGGCTACAATGTCGTAATGAAAGACGCCACTAATGCAGGCTTGTATCGCGGCGTTGGACAAATTCAAACCGGACTAAGTAATGCTGTGAAACGCAAAAGAATTTCATCTCTACAAAAGGATAAGTACTTATCGAATCTACTTCCTACATTGGACTATGCCAAGTTCAAAAATGCGGATTGTGTAATTGAAGCCGTTTTCGAGGATATTAACATCAAGCACAAAGTTATCAAAGAGTTAGAGGCTGTAGTGCCGAAACATTGTATTATAGCTACAAACACTAGTGCTATACCTATTACAAAAATCGCAGCTGGCAGCAGTCGTCCTGATAAAGTAATTGGCATGCATTACTTCTCACCAGTTGACAAGATGCAATTGCTAGAAATTATTAAGCACCCCGGCACCAGCGACGATACATCGGCAGCCGCTGTGGCCGTAGGTCTACGACAAGGAAAGGTCGTCATCACGGTGGGGGATGGGCCTGGTTTTTACACCACACGTATCCTTTCTACTATGCTTAGTGAAGCAGTAAGACTGCTACAAGAGGGTGTTGATCCTAAAGAACTGGATAACATGACAAAGCAATTTGGTTTCCCTGTCGGCGCTGCTACATTGGCTGACGAAGTTGGTATCGATGTCGGCTCTCACATCGCTGTGGATCTAGCCAAGGCCTTTGGTGATCGCATTAGCGGAGGAAACTTGGGTATCATGCAGGACTTAGTGCAAGCTGGATACATGGGACGCAAGTCCGGCAAAGGTTTCTATGTGTATGAAAAAGGCTCTAAAAACAGGGAAGTAAACCATGGTGCTATTAAAATCCTGAAAGACAAGTATGCATTAGAACCTCGTGGTGCTAATACTGTTGAAGACCAACAACTGCGAATGGTTTCCAGATTTGTAAATGAAGCAGTGTTATCATTGGAAGAAAAAATTCTACACAACCCCCTTGAAGGTGATGTTGGTGCGGTCTTTGGTCTCGGCTTCCCTCCATTTACTGGTGGACCTTTCAGATGGGTGGATCAATATGGCGCTGATAAATTAGTAAAGAAAATGGAGGAATACCAGGGTCTTTATGGCGCTCCATTCAAACCAGCTCAAACCCTTGTAGATATGGCCAAAGACACAAGTAAAAAATTCTATAAGAACTGA
Protein
MANSKILSALKILRSRKELFISGVHSRKYAVPASQVHTKCKLVNGVYVVTLDSPNVKVNSLNTQVMEEVSNIVNEIETNSGIEAAVIISGKPGCFIAGADISMIENCKTKEEVVSLSKRGHEIFRRIEQSRKPYIAAIQGSCLGGGLETALACKYRIAVKDSKTGFGLPEVMLGLLPGGGGTQRLPALTSIPTTLDLALTGKTVKADKAKKLGIVDLLVSPLGPGLGQPEENTAKYLETVAIQIAKDIAAGKIIVDRSKKGLVQKITAIVMQWEFVKNIIFKKAKEQVMKASRGLYPAPLKILEVVRTGVDKGPVAGYEAEAQGFGELAMTPQSKGLIGLFRGQTECKKNRFGKSQVDVKTIGVLGAGLMGAGIVQVSIDKGYNVVMKDATNAGLYRGVGQIQTGLSNAVKRKRISSLQKDKYLSNLLPTLDYAKFKNADCVIEAVFEDINIKHKVIKELEAVVPKHCIIATNTSAIPITKIAAGSSRPDKVIGMHYFSPVDKMQLLEIIKHPGTSDDTSAAAVAVGLRQGKVVITVGDGPGFYTTRILSTMLSEAVRLLQEGVDPKELDNMTKQFGFPVGAATLADEVGIDVGSHIAVDLAKAFGDRISGGNLGIMQDLVQAGYMGRKSGKGFYVYEKGSKNREVNHGAIKILKDKYALEPRGANTVEDQQLRMVSRFVNEAVLSLEEKILHNPLEGDVGAVFGLGFPPFTGGPFRWVDQYGADKLVKKMEEYQGLYGAPFKPAQTLVDMAKDTSKKFYKN

Summary

Similarity
Belongs to the enoyl-CoA hydratase/isomerase family.
EMBL
DQ311186    ABD36131.1    BABH01010547    BABH01010548    KQ459601    KPI93749.1    + More
KJ622097    AID66687.1    AGBW02009433    OWR50827.1    ODYU01007388    SOQ50103.1    KQ461196    KPJ06510.1    GAIX01004228    JAA88332.1    GGFJ01002356    MBW51497.1    GGFJ01002357    MBW51498.1    GANO01000770    JAB59101.1    GGFM01006565    MBW27316.1    GGFM01006543    MBW27294.1    GGFK01001446    MBW34767.1    ADMH02001533    ETN62152.1    GGFK01001404    MBW34725.1    ATLV01013284    KE524849    KFB37644.1    AXCM01004662    AXCN02002070    CH477641    EAT37915.1    EAT37916.1    DS234448    EDS34040.1    AAAB01008964    EAA12305.4    APCN01005201    CH900762    EAT32343.1    AJWK01030388    GAMD01001400    JAB00191.1    JXUM01114162    JXUM01114163    KQ565759    KXJ70695.1    GFDL01009278    JAV25767.1    GFDF01002560    JAV11524.1    GFDF01002561    JAV11523.1    OUUW01000010    SPP85691.1    CH479180    EDW28499.1    CH379060    EAL33439.2    CH940654    EDW57841.1    CH933807    EDW12235.1    CH963852    EDW75450.1    CH902624    EDV33025.2    CH954177    EDV58377.1    CM000157    EDW88656.1    AF181648    AE014134    AAD55434.1    AAF52789.1    AAN10697.1    CH480818    EDW52271.1    JXJN01009667    CM000361    CM002910    EDX04371.1    KMY89287.1    EZ424341    ADD20617.1    CP012523    ALC40225.1    KA647542    AFP62171.1    JRES01000864    KNC27681.1    CH916368    EDW03109.1    GEZM01001140    JAV98121.1    LJIG01022873    KRT78289.1    UFQS01000186    UFQS01001254    UFQT01000186    UFQT01001254    SSX00923.1    SSX09946.1    SSX21303.1    CCAG010008497    APGK01029294    APGK01029295    KB740731    KB632226    ENN79292.1    ERL90303.1    KQ971343    EFA04382.1    NNAY01000802    OXU26435.1    BT128501    AEE63458.1    GL435067    EFN74066.1    APGK01025474    APGK01025475    KB740591    ENN80162.1    GL452203    EFN77749.1    KK107238    QOIP01000007    EZA54760.1    RLU20785.1    KQ765234    OAD54016.1    GBXI01014555    GBXI01001154    JAC99736.1    JAD13138.1    CVRI01000052    CRK99700.1    KQ435748    KOX76405.1    KQ981219    KYN44447.1    GDHC01011565    JAQ07064.1    ADTU01019758    GBRD01011538    JAG54286.1    GBHO01014212    JAG29392.1    GBYB01011752    JAG81519.1    KK852514    KDR22191.1    KQ977957    KYM98488.1    KQ982919    KYQ49269.1    GEDC01013467    JAS23831.1    KQ980489    KYN15840.1    GBGD01000579    JAC88310.1    GFTR01007950    JAW08476.1    GAKP01018542    GAKP01018541    JAC40411.1   
Pfam
PF00725   3HCDH        + More
PF00378   ECH_1
PF02737   3HCDH_N
PF07690   MFS_1
PF14912   THEG
Interpro
IPR029045   ClpP/crotonase-like_dom_sf        + More
IPR006176   3-OHacyl-CoA_DH_NAD-bd       
IPR012803   Fa_ox_alpha_mit       
IPR008927   6-PGluconate_DH-like_C_sf       
IPR006108   3HC_DH_C       
IPR036291   NAD(P)-bd_dom_sf       
IPR001753   Enoyl-CoA_hydra/iso       
IPR018376   Enoyl-CoA_hyd/isom_CS       
IPR036259   MFS_trans_sf       
IPR011701   MFS       
IPR020846   MFS_dom       
IPR006623   THEG       
IPR006180   3-OHacyl-CoA_DH_CS       
SUPFAM
SSF48179   SSF48179        + More
SSF52096   SSF52096       
SSF51735   SSF51735       
SSF103473   SSF103473       
PDB
5ZRV     E-value=0,     Score=2066

Ontologies

Topology

Length:
762
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.227390000000001
Exp number, first 60 AAs:
0
Total prob of N-in:
0.00442
outside
1  -  762
 
 

Population Genetic Test Statistics

Pi
213.028583
Theta
202.937548
Tajima's D
-2.023671
CLR
0.517831
CSRT
0.0153492325383731
Interpretation
Uncertain
Peptides ×
Source Sequence Identity Evalue
26822097 KPYIAAIQGSCIGGGIETAIACK 96.43 2e-12
28467696 TGVCYDCKDNTDGPQCEICKPGYDR 96.43 2e-12
28556443 ISGGNLGIMQDLVQAGYMGR 100.00 4e-10
28556443 LVNGVYVVTLDSPNVK 100.00 6e-10
28556443 VIGMHYFSPVDK 100.00 6e-10
28556443 ISGGNLGIMQDLVQAGYMGR 100.00 2e-09
28556443 KLGIVDLLVSPLGPGLGQPEENTAK 100.00 2e-09
28556443 ILSTMLSEAVR 100.00 1e-06
28556443 ILSTMLSEAVR 100.00 1e-06
31250652 SSISLETLYPNSSLKLTTPAFVHTK 100.00 2e-06
28556443 HCIIATNTSAIPITK 100.00 3e-05
28556443 HCIIATNTSAIPITK 100.00 3e-05
28556443 LLQEGVDPK 100.00 5e-05
28556443 LGIVDLLVSPLGPGLGQPEENTAK 100.00 5e-05
26280517 MVVIQDGPNENSFKPQEKPIR 100.00 7e-05
28467696 NADAGIAIIR 100.00 7e-05
26822097 VIGMHYFSPVDK 100.00 3e-04
26280517 HASTTINQDEAVAR 100.00 3e-04
28467696 HCASPSAAGQIVIPESMK 100.00 3e-04
28556443 GVGQIQTGLSNAVK 100.00 3e-04
28556443 GVGQIQTGLSNAVK 100.00 3e-04
28556443 YYAGWADK 100.00 3e-04
26822097 HCIIATNTSAIPITK 100.00 5e-04
26280517 VVIEEPPIEENINR 100.00 5e-04
25044914 VVISDIDGTITK 100.00 5e-04
27102218 GANTVEDQQIR 100.00 5e-04
28467696 VVITSEEQFK 100.00 5e-04
28556443 VVITVGDGPGFYTTR 100.00 5e-04
28556443 VVITVGDGPGFYTTR 100.00 5e-04
28556443 VVITVGDGPGFYTTR 100.00 5e-04
28556443 LLQEGVDPK 100.00 5e-04
28556443 VVITVGDGPGFYTTR 100.00 5e-04
28556443 VVITVGDGPGFYTTR 100.00 5e-04
28556443 TGFGLPEVMLGLLPGGGGTQR 100.00 5e-04
28556443 TGFGLPEVMLGLLPGGGGTQR 100.00 5e-04
28556443 LPALTSIPTTLDLALTGK 100.00 7e-04
28556443 LPALTSIPTTLDLALTGK 100.00 7e-04
28556443 YLSNLLPTLDYAK 100.00 0.012
28556443 VVITVGDGPGFYTTR 100.00 0.012
28556443 VVITVGDGPGFYTTR 100.00 0.012
28556443 GANTVEDQQLR 100.00 0.040
28556443 FVNEAVLSLEEK 100.00 0.040
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