Gene

KWMTBOMO02047

Pre Gene Modal

BGIBMGA002965

Annotation

PREDICTED:_vacuolar_protein_sorting-associated_protein_52_homolog_isoform_X1_[Amyelois_transitella]

Location

Bomo_Chr4(+):11050837-11056245      View in EpiBrowser

Full name

Elongation factor G, mitochondrial      

Alternative Name

Elongation factor G 1, mitochondrial
Elongation factor G1

Location in the cell

Cytoplasmic   Reliability : 2.893

CDS

ATGTCTGATAACAACAACATGAACTTAGACAAAAATCTTGAGGATTTCGAAATCCAAGAGGTTCTCCGTAATGGTACAGATTTGCGAGAATATGCTCTTCAAATCGACAAAGGAATCATCGAAGCTGAAAAAGCATCTGTTGCGGATTATTTGAGAGAAAGTGAGAATATTGGCTCCCTTCATAATCAAATCGAAGAATGTGACAATATTTTAGGGAAAATGGAGAGTATGCTACTGGTGTTTCAGAATGATTTAGGAAGCATCAGCAATGAAATTATAAGTTTACAAAAGCGTTCAGTGAATATGTCAGTACAGTTATCTAATAGACAAGTGCTTAAGGGACCTTTATCTGCATTCATAGAAGACATGGCAGTGTCGGAAACTGTTATATTTGGTATCAACAATGTTCCAGTTACCGACAAAGAATTCATGGTGCAGTTGGCAATTTTAAACCAAAAATTAAATTTTGTAAAGGAACAAGATTTCAAAGAAACTAAAGCTTGTCATGATGTCAAAGACGTTTTGGAAAAATTAAAGATAAAAGCAGTGTCAAAGATAAGAACATATATTTTAGAACAAATATATAAATTCAGAAAACCAATGGCAAATTATCAAATACCACAAAATGCCATGCTGAAATACAAATTTTTCTTTGAATTTGTATTGACCAATGAACGAAATGTGGCTCAAGAAATTTGCAATGAATATATTGATACATTGAGCAAAGTTTATTATTCATACTTCAAGTCATATGCATCAAGACTAGATAAATTGAAATATGAAGAAGCACCCAACAAAGATGACTTAATGGGAATTGAGGATGGATCTAAAGGAGGATTCTTCCAGAAATCTAATTTAAAAAATAAAAGTACAATATTCACTATAGGGAATAGAGGTGATGTTCTGGCCCAACAACTAGAAGCACCCATTATTGTACCACATGTTCAGCAAAAAACAAAGTATTCATATGAAGCCTTATTTAGAAGTCTTCAATATGCCTTGGTAGACAATGGTTGCAGAGAATATCTGTTTACCACTGAATTCTTCCATGTCAAAGGAAACCATGCACAAGAGCTCTTTGATAGAATCCTCGGTAAAACATTGTCCGTGCTTGTAAAAAATGTGGAAAACTATGTAGTTGAATGTTATGATTGTTTGGCACTATTTCTTTGTATCCAATTAATAAACAGATATAAGTTAATGTGCCATAAAAGAGCAGTTGCGGCTCTGGACAGTTACTGGGAATCATTATACAACACTTTGTGGCCTCGGCTACAATATGTATTAAAACTGAACATTCAAAGCGTACGGGACTGCGACCCTTCTAAACTGTCAAACAAGGAAATGGGACCGCATTATATAACACGAAGGTACGCCGAATTTTCGGCAGCTATGCTGAGCCTCAGTGAACAATTCCCGTCTGAAGAACTCAGTAAACTTCTGACTGTACTTCAGGATGAAGTCCATTGTTTTTTACTTAAAATGGCTGCAGAGTTCCCTCAAAGAATACAACAGCTTATATTTTTAATTAATAATTACGACATGGTCCTCAGCATATTAATGGAAAGAACTAGAGACAACACAAAAGAAGCAGAAAGCTTCAGGGAACAATTACAGGGAAGAAGTTCAGAATATGTAGAAGAGATTCTCAGTCCACATTTTGGTGGAATGATACAGTTTGTCAAGGAATGTGAGCAATTGCTAGATGGTGATAAAAAGGCAGAATTAGCCGGATTAGAAAGAAAATCTCTATCCCTTGTAGCATCATTCAGTTCGGGATGGAAACAAAGTCTAGAAGAAATACATAGAGAAGTGCTAGTATCGTTTCCAAATCTAGTTACCGGGTCAGGTCTGTTGCAAATGGCGTTAACGAATTTCGTTCAATATTACCACAAATTTGTAAAACTTTTAACGCCCAGTGCCCGTACTCAATTAGTTAATATACATGTGATAATGGTAGAAATAAAAAAATATAAAACAAATTTTTAG

Protein

MSDNNNMNLDKNLEDFEIQEVLRNGTDLREYALQIDKGIIEAEKASVADYLRESENIGSLHNQIEECDNILGKMESMLLVFQNDLGSISNEIISLQKRSVNMSVQLSNRQVLKGPLSAFIEDMAVSETVIFGINNVPVTDKEFMVQLAILNQKLNFVKEQDFKETKACHDVKDVLEKLKIKAVSKIRTYILEQIYKFRKPMANYQIPQNAMLKYKFFFEFVLTNERNVAQEICNEYIDTLSKVYYSYFKSYASRLDKLKYEEAPNKDDLMGIEDGSKGGFFQKSNLKNKSTIFTIGNRGDVLAQQLEAPIIVPHVQQKTKYSYEALFRSLQYALVDNGCREYLFTTEFFHVKGNHAQELFDRILGKTLSVLVKNVENYVVECYDCLALFLCIQLINRYKLMCHKRAVAALDSYWESLYNTLWPRLQYVLKLNIQSVRDCDPSKLSNKEMGPHYITRRYAEFSAAMLSLSEQFPSEELSKLLTVLQDEVHCFLLKMAAEFPQRIQQLIFLINNYDMVLSILMERTRDNTKEAESFREQLQGRSSEYVEEILSPHFGGMIQFVKECEQLLDGDKKAELAGLERKSLSLVASFSSGWKQSLEEIHREVLVSFPNLVTGSGLLQMALTNFVQYYHKFVKLLTPSARTQLVNIHVIMVEIKKYKTNF

Description

Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

Similarity

Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.

Uniprot

H9J0C9   A0A2H1VY52   A0A2A4ITH4   A0A194QMD1   A0A194PLZ0   A0A212EHU0   + More
A0A336MKN1   A0A336LBA9   A0A2P8Z974   A0A1Y1MLZ8   D6WLS8   A0A232F3Q4   K7IM12   B4JAF8   B4Q3M2   A0A151WU06   A0A067R630   A0A182XN81   B4LU18   A0A195EKA6   B3MMY9   Q7Q1K6   A0A182U7K8   A0A182HRX9   A0A182K0G9   A0A0N0BF52   A0A182P4Q5   F4X1K8   B4MVJ3   Q29NU9   B4GJL3   A0A182H855   A0A088A6L7   A0A2A3E135   A0A2J7QPP5   A0A3B0K820   A0A182QIL5   A0A1W4UVG8   A0A182NBQ7   A0A182VIX7   A0A182T447   A0A195F4N7   B3N4W6   A0A151I8T1   B4P061   A0A182Y0M9   Q9VMQ8   Q16HD1   A0A084WU37   A0A182MS30   A0A1A9XER7   A0A182J5D7   A0A182WGI3   A0A1B0C1M9   A0A1Q3FE00   A0A1B0FPK8   A0A2M4BGL3   A0A182R3S9   A0A182F0X9   A0A2M4BGJ0   A0A1I8NWE3   B4I1G6   A0A2M3Z3J2   B4KF31   Q86NL4   A0A0L0CMB5   W5JGX8   W8BP42   A0A1A9WKI6   A0A154P7J8   A0A0M5IYU2   A0A2M4AL70   A0A1I8MWX6   A0A0A1XG69   A0A026W273   A0A0M3QSZ7   A0A158NK85   B0WGM0   A0A0K8UT38   A0A1B6C1U5   A0A034VG26   E2A6W1   A0A195BU53   A0A1A9Z7Z1   E9IAV9   A0A1J1IQM4   A0A1B6KEV3   A0A1B6ELU5   A0A069DWA2   T1I6Q1   A0A023F2U6   J3JWF0   A0A1A9VCC6   A0A0L7R4S6   A0A131YWZ2   A0A224ZBT4   A0A0V0G8D5   A0A1L8DVE9   A0A2L2Y8V5   C3Y4K0  

Pubmed

19121390    26354079    22118469    29403074    28004739    18362917    + More
19820115    28648823    20075255    17994087    22936249    24845553    12364791    21719571    15632085    26483478    17550304    25244985    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    17510324    24438588    26108605    20920257    23761445    24495485    25315136    25830018    24508170    30249741    21347285    25348373    20798317    21282665    26334808    25474469    22516182    23537049    26830274    28797301    26561354    18563158   

EMBL

BABH01010554    ODYU01005169    SOQ45770.1    NWSH01008707    PCG62443.1    KQ461196    + More
KPJ06514.1    KQ459601    KPI93754.1    AGBW02014799    OWR41044.1    UFQT01001105    SSX28937.1    UFQS01002506    UFQT01002506    SSX14181.1    SSX33597.1    PYGN01000141    PSN53047.1    GEZM01033531    JAV84227.1    KQ971343    EFA03408.1    NNAY01001056    OXU25315.1    CH916368    EDW03829.1    CM000361    CM002910    EDX03826.1    KMY88305.1    KQ982757    KYQ51115.1    KK852678    KDR18670.1    CH940649    EDW65071.1    KQ978801    KYN28294.1    CH902620    EDV31014.1    AAAB01008980    EAA14212.2    APCN01001775    KQ435812    KOX72831.1    GL888531    EGI59666.1    CH963857    EDW75713.1    CH379058    EAL34545.2    CH479184    EDW36829.1    JXUM01028750    KQ560831    KXJ80692.1    KZ288467    PBC25410.1    NEVH01012088    PNF30557.1    OUUW01000006    SPP82179.1    AXCN02000684    KQ981805    KYN35545.1    CH954177    EDV57868.1    KQ978331    KYM95071.1    CM000157    EDW88926.1    AE014134    BT150341    AAF52254.1    AGW25623.1    CH478183    CH477842    EAT33644.1    EAT35738.1    ATLV01026995    KE525421    KFB53731.1    AXCM01001134    JXJN01024136    GFDL01009327    JAV25718.1    CCAG010008058    GGFJ01003023    MBW52164.1    GGFJ01003024    MBW52165.1    CH480820    EDW54373.1    GGFM01002329    MBW23080.1    CH933807    EDW13014.1    BT004855    AAO45211.1    JRES01000186    KNC33488.1    ADMH02001427    ETN62578.1    GAMC01005898    JAC00658.1    KQ434823    KZC07304.1    CP012523    ALC40124.1    GGFK01008037    MBW41358.1    GBXI01004789    JAD09503.1    KK107538    QOIP01000005    EZA49134.1    RLU22919.1    ALC38033.1    ADTU01002053    DS231927    EDS27049.1    GDHF01022462    JAI29852.1    GEDC01030103    JAS07195.1    GAKP01018429    JAC40523.1    GL437203    EFN70827.1    KQ976403    KYM92139.1    GL762073    EFZ22289.1    CVRI01000055    CRL01398.1    GEBQ01030001    JAT09976.1    GECZ01030872    JAS38897.1    GBGD01000768    JAC88121.1    ACPB03019922    GBBI01003189    JAC15523.1    APGK01037223    BT127568    KB740948    KB632348    AEE62530.1    ENN77276.1    ERL93173.1    KQ414657    KOC65838.1    GEDV01005485    JAP83072.1    GFPF01013266    MAA24412.1    GECL01001902    JAP04222.1    GFDF01003687    JAV10397.1    IAAA01012485    IAAA01012486    IAAA01012487    LAA04574.1    GG666486    EEN64657.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000053268    UP000007151    UP000245037    + More
UP000007266    UP000215335    UP000002358    UP000001070    UP000000304    UP000075809    UP000027135    UP000076407    UP000008792    UP000078492    UP000007801    UP000007062    UP000075902    UP000075840    UP000075881    UP000053105    UP000075885    UP000007755    UP000007798    UP000001819    UP000008744    UP000069940    UP000249989    UP000005203    UP000242457    UP000235965    UP000268350    UP000075886    UP000192221    UP000075884    UP000075903    UP000075901    UP000078541    UP000008711    UP000078542    UP000002282    UP000076408    UP000000803    UP000008820    UP000030765    UP000075883    UP000092443    UP000075880    UP000075920    UP000092460    UP000092444    UP000075900    UP000069272    UP000095300    UP000001292    UP000009192    UP000037069    UP000000673    UP000091820    UP000076502    UP000092553    UP000095301    UP000053097    UP000279307    UP000005205    UP000002320    UP000000311    UP000078540    UP000092445    UP000183832    UP000015103    UP000019118    UP000030742    UP000078200    UP000053825    UP000001554   

PRIDE

H9J0C9    Q9VMQ8    Q86NL4   

Pfam

PF04129   Vps52        + More
PF14492   EFG_II
PF00009   GTP_EFTU
PF00679   EFG_C
PF03144   GTP_EFTU_D2
PF03764   EFG_IV

Interpro

IPR007258   Vps52        + More
IPR005517   Transl_elong_EFG/EF2_IV       
IPR041095   EFG_II       
IPR035649   EFG_V       
IPR004161   EFTu-like_2       
IPR009000   Transl_B-barrel_sf       
IPR027417   P-loop_NTPase       
IPR035647   EFG_III/V       
IPR020568   Ribosomal_S5_D2-typ_fold       
IPR031157   G_TR_CS       
IPR005225   Small_GTP-bd_dom       
IPR000640   EFG_V-like       
IPR004540   Transl_elong_EFG/EF2       
IPR000795   TF_GTP-bd_dom       
IPR009022   EFG_III       
IPR014721   Ribosomal_S5_D2-typ_fold_subgr       

SUPFAM

SSF54211   SSF54211        + More
SSF54980   SSF54980       
SSF52540   SSF52540       
SSF50447   SSF50447       

Gene 3D

3.30.230.10    

CDD

cd04097  mtEFG1_C
cd16262  EFG_III
cd01434  EFG_mtEFG1_IV

ProteinModelPortal

H9J0C9   A0A2H1VY52   A0A2A4ITH4   A0A194QMD1   A0A194PLZ0   A0A212EHU0   + More
A0A336MKN1   A0A336LBA9   A0A2P8Z974   A0A1Y1MLZ8   D6WLS8   A0A232F3Q4   K7IM12   B4JAF8   B4Q3M2   A0A151WU06   A0A067R630   A0A182XN81   B4LU18   A0A195EKA6   B3MMY9   Q7Q1K6   A0A182U7K8   A0A182HRX9   A0A182K0G9   A0A0N0BF52   A0A182P4Q5   F4X1K8   B4MVJ3   Q29NU9   B4GJL3   A0A182H855   A0A088A6L7   A0A2A3E135   A0A2J7QPP5   A0A3B0K820   A0A182QIL5   A0A1W4UVG8   A0A182NBQ7   A0A182VIX7   A0A182T447   A0A195F4N7   B3N4W6   A0A151I8T1   B4P061   A0A182Y0M9   Q9VMQ8   Q16HD1   A0A084WU37   A0A182MS30   A0A1A9XER7   A0A182J5D7   A0A182WGI3   A0A1B0C1M9   A0A1Q3FE00   A0A1B0FPK8   A0A2M4BGL3   A0A182R3S9   A0A182F0X9   A0A2M4BGJ0   A0A1I8NWE3   B4I1G6   A0A2M3Z3J2   B4KF31   Q86NL4   A0A0L0CMB5   W5JGX8   W8BP42   A0A1A9WKI6   A0A154P7J8   A0A0M5IYU2   A0A2M4AL70   A0A1I8MWX6   A0A0A1XG69   A0A026W273   A0A0M3QSZ7   A0A158NK85   B0WGM0   A0A0K8UT38   A0A1B6C1U5   A0A034VG26   E2A6W1   A0A195BU53   A0A1A9Z7Z1   E9IAV9   A0A1J1IQM4   A0A1B6KEV3   A0A1B6ELU5   A0A069DWA2   T1I6Q1   A0A023F2U6   J3JWF0   A0A1A9VCC6   A0A0L7R4S6   A0A131YWZ2   A0A224ZBT4   A0A0V0G8D5   A0A1L8DVE9   A0A2L2Y8V5   C3Y4K0  

KEGG

101744187    K20298 vacuolar protein sorting-associated protein 52 | (RefSeq) vacuolar protein sorting-associated

GO

GO:0007041   GO:0000938   GO:0005829   GO:0042147   GO:0032456   GO:0019905   GO:0006896   GO:0017137   GO:0005802   GO:0055037   GO:0005794   GO:0005525   GO:0003746   GO:0003924   GO:0005739   GO:0070125   GO:0016021  

PANTHER

PTHR14190  

Subcellular location

Mitochondrion  

Length:

662

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.68031

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00161

outside

1  -  662

 

 

Pi

310.382074

Theta

199.763794

Tajima's D

1.710038

CLR

0

CSRT

0.832358382080896

Interpretation

Uncertain