Gene

KWMTBOMO02036  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA003207

Annotation

PREDICTED:_negative_elongation_factor_E_[Amyelois_transitella]

Location

Bomo_Chr4(-):10748601-10751839      View in EpiBrowser

Full name

Negative elongation factor E      

Location in the cell

Nuclear   Reliability : 4.147

CDS

ATGGTCTATTTACATTTTCCTTCGAACCTAACCGAGGAAGAACTAATGCTACAAGCTAAATACCAGAAACTAAAAAAGAAGAAGAAAGCTTTGCAAGCCCTTAAGGCACCAAAACCCGAACCAGAAAAGCCAATTTTACCAAAAAGGCCTACAGAAGCCAGAGATGCCAGGGAAATAGCTAGAAAATTGCTGAAAAGTGGTGCTATTCAAGCTATTAAAAGTCCTCCAACTCAGCCACAGAACACCACTTTCAAAAAACCACGTGCAGGTCGAGAAAGGAAATTAAGTGGTTCTGCTGGAGTACCTGGAGGTGTTGCTTCATATCAACCATTCAGTGCTTCACAAGAACCTCCACCTCAAGAAGAGAAACAAACTCCAAGAGTTAAATATCTTTATGACTCTTTTGTCACTGCCAGAGAAAAGGACGACAAAGGCTCACGCACACCCAATCCAGGTGGCAGTACACCGTCTCAATCAGATGGTCGCAGTTGTACTTTACAATTGGTCGGTCAACGGATATCTGAAGAGATATTGAGGAGACGCCTGGCTACTTTTGAGCCCTTTGCATTCATGCCAAAAGATGACAAGGCTTTCTTAACCTTCGATAGTCCTGACATTGCGTCGCACGCTTTGTCGGCTCTTGAAGGCAACGAGGAGGGCTGGCGTATAAACATCGCGAGAAGACCTCCGCAGCAACAAGGGACTTGGAGTGCGTCGTCTTCACCACGAAATCCACAACCGCCTCCCAAGGACTTGAAACGTACATTATTGACTTATGATGATATATTTGATTAA

Protein

MVYLHFPSNLTEEELMLQAKYQKLKKKKKALQALKAPKPEPEKPILPKRPTEARDAREIARKLLKSGAIQAIKSPPTQPQNTTFKKPRAGRERKLSGSAGVPGGVASYQPFSASQEPPPQEEKQTPRVKYLYDSFVTAREKDDKGSRTPNPGGSTPSQSDGRSCTLQLVGQRISEEILRRRLATFEPFAFMPKDDKAFLTFDSPDIASHALSALEGNEEGWRINIARRPPQQQGTWSASSSPRNPQPPPKDLKRTLLTYDDIFD

Description

Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex, causes transcriptional pausing.
Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex, causes transcriptional pausing (By similarity).

Subunit

Component of the NELF complex, which is at least composed of TH1/Nelf-D and Nelf-E.
Component of the NELF complex, which is at least composed of TH1/NELF-D and NELF-E.

Similarity

Belongs to the RRM NELF-E family.

Keywords

Chromosome   Complete proteome   Nucleus   Reference proteome   Repressor   RNA-binding   Transcription   Transcription regulation  

Feature

chain  Negative elongation factor E

Uniprot

H9J120   A0A212EHU8   A0A2H1VZM0   A0A2A4K4E6   A0A194PL88   I4DRH2   + More
A0A0L7L4E7   A0A194QME1   S4PKE8   A0A1E1WBN8   A0A1B6M8G1   A0A1B6G9Y2   A0A067R779   V5FXT6   A0A088A9Q8   D6WEE5   N6UEI7   A0A1Y1LEN3   A0A232FDW5   A0A310S6S8   A0A0L7QX51   A0A182YKZ2   E0W480   A0A182LLJ2   Q7Q5S3   A0A2A3EP91   A0A1L8DSL7   Q0IG90   A0A2M4AUP3   W5JIR8   A0A154P8M4   A0A1B6EGY2   A0A2M3ZCG7   A0A2J7RG74   E9HI81   U5ENW6   W8B6I8   A0A182MIL1   A0A0P6DW17   A0A2M4BVC0   A0A182I161   A0A1A9UJC6   A0A182VN84   A0A1W4WJN1   A0A1A9YN44   A0A1B0BHX8   A0A182WLS0   A0A182UE00   B4KZ57   A0A1A9Z2R2   E2AJZ5   A0A151WWJ0   E2BRF5   B3NBR3   A0A023EMA8   A0A0J7K8A0   B4PG02   A0A2M4BVD4   A0A2M4BWB4   A0A182JSS4   K7J8E4   A0A182PL93   A0A182FHR0   A0A1W4US37   A0A1S4F3Y9   A0A1A9WIA1   P92204   A0A0J9RT11   B4HJZ8   A0A158NNJ0   A0A195B2P9   A0A195DKM2   A0A0N0U3M1   A0A151I9U1   B4IWM1   A0A195F6M1   B4LEK7   A0A1S4EPU6   A0A026WC07   A0A182H4S0   F4WQF1   A0A336MND3   A0A0N8AZR8   A0A336M931   Q95ZE9   A0A0K8UF00   A0A034VPP1   A0A0P6AG97   A0A1I8MR11   B3M688   A0A182N947   B4MXU2   A0A1I8PRN4   A0A182QLE9   A0A3B0JBI9   A0A182X8L1   Q29D00   B4H9I0   A0A2P2IAF6  

Pubmed

19121390    22118469    26354079    22651552    26227816    23622113    + More
24845553    18362917    19820115    23537049    28004739    28648823    25244985    20566863    20966253    12364791    17510324    20920257    23761445    21292972    24495485    17994087    20798317    24945155    26483478    17550304    20075255    9236770    10731132    12537572    12537569    12782658    22936249    21347285    24508170    30249741    21719571    11814692    25348373    25315136    15632085   

EMBL

BABH01010587    AGBW02014799    OWR41055.1    ODYU01005437    SOQ46281.1    NWSH01000140    + More
PCG79131.1    KQ459601    KPI93763.1    AK405118    BAM20512.1    JTDY01002995    KOB70352.1    KQ461196    KPJ06524.1    GAIX01001036    JAA91524.1    GDQN01006646    JAT84408.1    GEBQ01023873    GEBQ01007761    JAT16104.1    JAT32216.1    GECZ01010533    JAS59236.1    KK852694    KDR18301.1    GALX01005986    JAB62480.1    KQ971318    EFA00397.1    APGK01025467    KB740591    KB632226    ENN80155.1    ERL90296.1    GEZM01057940    JAV72084.1    NNAY01000392    OXU28693.1    KQ767283    OAD53454.1    KQ414705    KOC63119.1    DS235886    EEB20436.1    AAAB01008960    EAA10770.4    KZ288212    PBC32851.1    GFDF01004769    JAV09315.1    CH477261    EAT45667.1    GGFK01011184    MBW44505.1    ADMH02001054    ETN64277.1    KQ434846    KZC08269.1    GEDC01027159    GEDC01023196    GEDC01019531    GEDC01003222    GEDC01000102    JAS10139.1    JAS14102.1    JAS17767.1    JAS34076.1    JAS37196.1    GGFM01005424    MBW26175.1    NEVH01004403    PNF39839.1    GL732653    EFX68534.1    GANO01000418    JAB59453.1    GAMC01009755    JAB96800.1    AXCM01000856    GDIP01158400    GDIQ01071421    LRGB01003128    JAJ65002.1    JAN23316.1    KZS04155.1    GGFJ01007876    MBW57017.1    APCN01000031    JXJN01014624    CH933809    EDW17854.1    GL440121    EFN66240.1    KQ982691    KYQ52274.1    GL449962    EFN81733.1    CH954178    EDV50659.1    JXUM01009569    GAPW01003162    KQ560286    JAC10436.1    KXJ83270.1    LBMM01011969    KMQ86514.1    CM000159    EDW93146.1    GGFJ01007878    MBW57019.1    GGFJ01007877    MBW57018.1    Y10015    Y10016    AE014296    AY071061    CM002912    KMY98424.1    CH480815    EDW40734.1    ADTU01021611    KQ976641    KYM78748.1    KQ980765    KYN13428.1    KQ435891    KOX69424.1    KQ978273    KYM95777.1    CH916366    EDV96247.1    KQ981744    KYN36245.1    CH940647    EDW69092.1    KK107288    QOIP01000013    EZA53508.1    RLU15488.1    JXUM01025526    KQ560725    KXJ81123.1    GL888273    EGI63551.1    UFQT01001837    SSX31964.1    GDIQ01226915    JAK24810.1    UFQT01000264    SSX22558.1    AJ306692    GDHF01029381    GDHF01027141    GDHF01017011    GDHF01006976    JAI22933.1    JAI25173.1    JAI35303.1    JAI45338.1    GAKP01015182    JAC43770.1    GDIP01031154    JAM72561.1    CH902618    EDV39708.1    CH963876    EDW76861.1    AXCN02000488    OUUW01000002    SPP77402.1    CH379070    EAL30614.1    CH479229    EDW36456.1    IACF01005414    LAB70999.1   

Proteomes

UP000005204    UP000007151    UP000218220    UP000053268    UP000037510    UP000053240    + More
UP000027135    UP000005203    UP000007266    UP000019118    UP000030742    UP000215335    UP000053825    UP000076408    UP000009046    UP000075882    UP000007062    UP000242457    UP000008820    UP000000673    UP000076502    UP000235965    UP000000305    UP000075883    UP000076858    UP000075840    UP000078200    UP000075903    UP000192223    UP000092443    UP000092460    UP000075920    UP000075902    UP000009192    UP000092445    UP000000311    UP000075809    UP000008237    UP000008711    UP000069940    UP000249989    UP000036403    UP000002282    UP000075881    UP000002358    UP000075885    UP000069272    UP000192221    UP000091820    UP000000803    UP000001292    UP000005205    UP000078540    UP000078492    UP000053105    UP000078542    UP000001070    UP000078541    UP000008792    UP000079169    UP000053097    UP000279307    UP000007755    UP000095301    UP000007801    UP000075884    UP000007798    UP000095300    UP000075886    UP000268350    UP000076407    UP000001819    UP000008744   

PRIDE

H9J120    P92204   

Pfam

PF00076   RRM_1        + More
PF13086   AAA_11
PF10241   KxDL
PF13087   AAA_12

Interpro

IPR033102   NELFE        + More
IPR035979   RBD_domain_sf       
IPR034637   NELFE_RRM       
IPR012677   Nucleotide-bd_a/b_plait_sf       
IPR000504   RRM_dom       
IPR027417   P-loop_NTPase       
IPR041677   DNA2/NAM7_AAA_11       
IPR019371   Uncharacterised_KxDL       
IPR041679   DNA2/NAM7-like_AAA       

SUPFAM

SSF54928   SSF54928        + More
SSF52540   SSF52540       

Gene 3D

3.30.70.330    

CDD

cd12305  RRM_NELFE

ProteinModelPortal

H9J120   A0A212EHU8   A0A2H1VZM0   A0A2A4K4E6   A0A194PL88   I4DRH2   + More
A0A0L7L4E7   A0A194QME1   S4PKE8   A0A1E1WBN8   A0A1B6M8G1   A0A1B6G9Y2   A0A067R779   V5FXT6   A0A088A9Q8   D6WEE5   N6UEI7   A0A1Y1LEN3   A0A232FDW5   A0A310S6S8   A0A0L7QX51   A0A182YKZ2   E0W480   A0A182LLJ2   Q7Q5S3   A0A2A3EP91   A0A1L8DSL7   Q0IG90   A0A2M4AUP3   W5JIR8   A0A154P8M4   A0A1B6EGY2   A0A2M3ZCG7   A0A2J7RG74   E9HI81   U5ENW6   W8B6I8   A0A182MIL1   A0A0P6DW17   A0A2M4BVC0   A0A182I161   A0A1A9UJC6   A0A182VN84   A0A1W4WJN1   A0A1A9YN44   A0A1B0BHX8   A0A182WLS0   A0A182UE00   B4KZ57   A0A1A9Z2R2   E2AJZ5   A0A151WWJ0   E2BRF5   B3NBR3   A0A023EMA8   A0A0J7K8A0   B4PG02   A0A2M4BVD4   A0A2M4BWB4   A0A182JSS4   K7J8E4   A0A182PL93   A0A182FHR0   A0A1W4US37   A0A1S4F3Y9   A0A1A9WIA1   P92204   A0A0J9RT11   B4HJZ8   A0A158NNJ0   A0A195B2P9   A0A195DKM2   A0A0N0U3M1   A0A151I9U1   B4IWM1   A0A195F6M1   B4LEK7   A0A1S4EPU6   A0A026WC07   A0A182H4S0   F4WQF1   A0A336MND3   A0A0N8AZR8   A0A336M931   Q95ZE9   A0A0K8UF00   A0A034VPP1   A0A0P6AG97   A0A1I8MR11   B3M688   A0A182N947   B4MXU2   A0A1I8PRN4   A0A182QLE9   A0A3B0JBI9   A0A182X8L1   Q29D00   B4H9I0   A0A2P2IAF6  

KEGG

101745628    K15182 negative elongation factor E | (RefSeq) negative elongation factor E

GO

GO:0032021   GO:0006355   GO:0003746   GO:0003676   GO:0003723   GO:0034244   GO:0017053   GO:0045944   GO:0006368   GO:0005694   GO:0005634   GO:0032785   GO:0000122   GO:0003729   GO:0008023  

PANTHER

PTHR17250  

Subcellular location

Nucleus  
Chromosome  

Length:

264

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00019

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00789

outside

1  -  264

 

 

Pi

49.436336

Theta

6.587306

Tajima's D

-0.764273

CLR

0.711706

CSRT

0.182740862956852

Interpretation

Uncertain