Gene

KWMTBOMO02025  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA002953

Annotation

PREDICTED:_probable_26S_proteasome_non-ATPase_regulatory_subunit_3_[Amyelois_transitella]

Location

Bomo_Chr4(+):10608851-10610531      View in EpiBrowser

Full name

Probable 26S proteasome non-ATPase regulatory subunit 3      

Alternative Name

26S proteasome regulatory subunit RPN3
Diphenol oxidase A2 component

Location in the cell

Nuclear   Reliability : 2.306

CDS

ATGGCTCCAGTGGAAGATGTTGAAATGAAAAATGTGGAAAGTCCTGCAGCTGTTAGTGACGTTGAGACAGCGGATGTAAAGAAAGATGCTGATGTACTAGCTGTTCAGGATCTACGAGAACACATCAGACAAATCGATAAAGCTGTTACTTCGAAAGAACCTAGATTCGCTATGCGTGTACTTAGAGCACTGCCGAGCACTCGCAGGAAGTTAAACGGTAACGTTCTGCGAGCTATTATCAATCAGATTTATCCCGCTAGTGCTGAGAAAGAAACCATACTATCTTTTGTGGAAAATCCTCTCCCTGGTGCCGTAGAAATAGAAGCTCCCAGGTCACGAAGCGCCCCTAAGCAGCCAGTGCCCGAAGTGGATACATATTTGCATCTCCTTGTGCTGTTACGTTTGTTGGATACAAACAAACTTGAAGAAGCCACAGAATGCTCTCAGCAACTAATGACAAAAGTTACTACTCAAAATCGAAGAACCCTTGACTTGATTGCTGCAAAATGCTATTTTTATCACTCAAGAGTGTTTGAACTAACTAACAAGTTGGATGTGATCAGAGGTCTCTTACATGCCCGACTTCGTACATCAACATTGAGAAATGACTATGAAGGTCAAGCTGTTATTATCAACTGCCTGTTGAGAAATTACTTGCACTACTCTTTGTATGATCAAGCCGATAAATTAGTAAGTAAGTCAGTTTTTCCTGAAAATGCCAGCAACAATGAGTGGGCAAGATTTCTGTACTACCTTGGCAGAATAAAAGCAGCAAGGTTAGAATACAGTGATGCACACAAACATCTAGTGCAGGCTTTAAGAAAAGCTCCCCAAACAGCTGCTGTTGGATTCCGTCAAACGGTCCAAAAATTAGCAATTGTAGTGGAATTGCTATTAGGTGATATACCGGAGCGAGTGATTTTCCGTCAAGCTCCACTTCGTAAAGCATTAGCTCCATATTTCCAGCTCACCCAAGCTGTGCGTCTTGGAAACTTGCAAAGATTTGGTGAAGTATTGGAGAATTATGGGCCACAGTTCCGAAATGATCACACATTTACATTGATCCTTCGTCTTAGACAGAATGTTATTAAGACTGCTATTCGTTCAATTGGATTGTCCTATTCTCGCATATCACCAAAAGATATAGCTCGCAAATTAGGGCTTGACTCTGCTGAAGATGCAGAATTCATTGTTGCTAAGGCAATCAGAGATGGAGTGATTGAGGCAACATTAGACCCTGTAAAGGGCTACATGAGTAATAAAGAAAGCTCAGATATTTATTGTACTAGAGAGCCACAGTTAGCCTTTCATCAGCGGATTTCATTTTGCCTAGATTTACACAACCAAAGTGTTAAGGCAATGAGATATCCACCAAAATCATACGGAAAAGAATTGGAAAGTGCTGAGGAACGCCGTGAAAGAGAACAGCAAGATCTGGAACTTGCCAAAGAAATGGCAGAGGAAGATGATGATGGTTTCCCATGA

Protein

MAPVEDVEMKNVESPAAVSDVETADVKKDADVLAVQDLREHIRQIDKAVTSKEPRFAMRVLRALPSTRRKLNGNVLRAIINQIYPASAEKETILSFVENPLPGAVEIEAPRSRSAPKQPVPEVDTYLHLLVLLRLLDTNKLEEATECSQQLMTKVTTQNRRTLDLIAAKCYFYHSRVFELTNKLDVIRGLLHARLRTSTLRNDYEGQAVIINCLLRNYLHYSLYDQADKLVSKSVFPENASNNEWARFLYYLGRIKAARLEYSDAHKHLVQALRKAPQTAAVGFRQTVQKLAIVVELLLGDIPERVIFRQAPLRKALAPYFQLTQAVRLGNLQRFGEVLENYGPQFRNDHTFTLILRLRQNVIKTAIRSIGLSYSRISPKDIARKLGLDSAEDAEFIVAKAIRDGVIEATLDPVKGYMSNKESSDIYCTREPQLAFHQRISFCLDLHNQSVKAMRYPPKSYGKELESAEERREREQQDLELAKEMAEEDDDGFP

Description

Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.

Subunit

The 26S proteasome is composed of a core protease, known as the 20S proteasome, capped at one or both ends by the 19S regulatory complex (RC). The RC is composed of at least 18 different subunits in two subcomplexes, the base and the lid, which form the portions proximal and distal to the 20S proteolytic core, respectively (By similarity).

Similarity

Belongs to the proteasome subunit S3 family.

Keywords

Complete proteome   Proteasome   Reference proteome  

Feature

chain  Probable 26S proteasome non-ATPase regulatory subunit 3

Uniprot

H9J0B7   A0A2A4JY67   A0A2H1X096   A0A1E1WF21   I4DK33   A0A194RD45   + More
S4PGF7   A0A212FA38   A0A0L7LEF5   A0A2P8XTW6   V5GN64   A0A0C5AST9   A0A1B0DLH7   A0A2J7QBQ9   A0A1B6DCY0   B0WCQ3   A0A182K3Q3   A0A1Q3FAL3   A0A1B6FCJ6   N6THH0   A0A182R9S0   U4U1Q6   A0A067QNT9   A0A182MIP1   A0A182NEV7   A0A182PDF1   A0A023EU98   A0A2M4ADN7   Q16N14   A0A2M3ZH99   A0A182F5I5   W5JD00   A0A182YFG0   A0A182WGX4   A0A2M4BLH4   A0A182H859   U5EZB6   D6WL27   A0A182JBK4   A0A084VMC7   A0A182QVK3   A0A336KQ90   A0A1Y1MR71   A0A1L8DT32   A0A182VCR5   A0A182TT01   A0A182X2Y2   A0A182I4X2   O61470   A0A336K9E6   A0A232FC54   K7IPX0   A0A1J1I086   A0A0V0G3R3   A0A023FCV2   A0A069DU15   E2BQ36   A0A0P4VL30   A0A158NV98   A0A0A9Y084   A0A195B8F8   A0A0C9RE25   A0A0N0BHA9   E0VFN6   A0A195FV61   A0A026WTC0   E9IDJ2   E2AFJ6   A0A195ED72   A0A0K8WG40   A0A0J7L773   A0A034WS53   A0A2A3ET91   A0A154PIE7   A0A310SLR7   D3TN58   A0A1A9V9I3   A0A1W4XAH9   A0A1B0A540   A0A1A9W063   Q9U5Z8   A0A1B0G931   T1I033   A0A2R7W1Z7   A0A0L7RGT6   A0A088ASB8   W8C3L9   A0A1B0B7N7   A0A1A9XL20   A0A151IPB9   R4WQT4   B4N147   B4LS14   F4WNN9   A0A3B0JVU4   B4JAM3   Q29PI4   B4GKT7   A0A1I8MWP0   A0A1W4WA38  

Pubmed

19121390    22651552    26354079    23622113    22118469    26227816    + More
29403074    25653432    29136191    23537049    24845553    24945155    17510324    20920257    23761445    25244985    26483478    18362917    19820115    24438588    28004739    9988317    12364791    28648823    20075255    25474469    26334808    20798317    27129103    21347285    25401762    26823975    20566863    24508170    30249741    21282665    25348373    20353571    10835480    24495485    23691247    17994087    21719571    15632085    25315136   

EMBL

BABH01010598    NWSH01000407    PCG76618.1    ODYU01012450    SOQ58759.1    GDQN01005527    + More
JAT85527.1    AK401651    KQ459601    BAM18273.1    KPI93769.1    KQ460597    KPJ13831.1    GAIX01003697    JAA88863.1    AGBW02009527    OWR50594.1    JTDY01001441    KOB73852.1    PYGN01001356    PSN35451.1    GALX01005464    JAB63002.1    KM999967    QKKF02030719    AJK90582.1    RZF34685.1    AJVK01006652    NEVH01016296    PNF26024.1    GEDC01013747    JAS23551.1    DS231890    EDS43779.1    GFDL01010421    JAV24624.1    GECZ01021837    JAS47932.1    APGK01037110    KB740948    ENN77223.1    KB631899    ERL86992.1    KK853129    KDR10975.1    AXCM01001875    GAPW01001112    JAC12486.1    GGFK01005576    MBW38897.1    CH477842    EAT35739.1    GGFM01007151    MBW27902.1    ADMH02001866    ETN60770.1    GGFJ01004672    MBW53813.1    JXUM01028759    KQ560831    KXJ80696.1    GANO01001087    JAB58784.1    KQ971343    EFA04054.1    ATLV01014585    KE524975    KFB39121.1    AXCN02000840    UFQS01000634    UFQT01000634    SSX05595.1    SSX25954.1    GEZM01025134    JAV87568.1    GFDF01004537    JAV09547.1    APCN01003737    AF042732    AAAB01008984    UFQS01000222    UFQT01000222    SSX01576.1    SSX21956.1    NNAY01000436    OXU28406.1    CVRI01000037    CRK93677.1    GECL01003420    JAP02704.1    GBBI01000213    JAC18499.1    GBGD01001286    JAC87603.1    GL449694    EFN82224.1    GDKW01001493    JAI55102.1    ADTU01002880    GBHO01020659    GBHO01020658    GBRD01007483    GDHC01000011    JAG22945.1    JAG22946.1    JAG58338.1    JAQ18618.1    KQ976565    KYM80527.1    GBYB01014809    JAG84576.1    KQ435756    KOX75984.1    DS235123    EEB12192.1    KQ981215    KYN44530.1    KK107109    QOIP01000008    EZA59310.1    RLU19538.1    GL762454    EFZ21345.1    GL439118    EFN67747.1    KQ979074    KYN22772.1    GDHF01002183    JAI50131.1    LBMM01000342    LBMM01000325    KMR00160.1    KMR01328.1    GAKP01001478    JAC57474.1    KZ288191    PBC34426.1    KQ434905    KZC11264.1    KQ761155    OAD58138.1    OAD58139.1    EZ422860    ADD19136.1    AJ250874    CCAG010004816    ACPB03012597    KK854249    PTY13702.1    KQ414592    KOC70192.1    GAMC01002712    JAC03844.1    JXJN01009696    KQ976874    KYN07686.1    AK418031    BAN21246.1    CH963920    EDW78137.1    CH940649    EDW63690.1    GL888237    EGI64232.1    OUUW01000010    SPP86217.1    CH916368    EDW02809.1    CH379058    EAL34309.1    CH479184    EDW37253.1   

Proteomes

UP000005204    UP000218220    UP000053268    UP000053240    UP000007151    UP000037510    + More
UP000245037    UP000291343    UP000092462    UP000235965    UP000002320    UP000075881    UP000019118    UP000075900    UP000030742    UP000027135    UP000075883    UP000075884    UP000075885    UP000008820    UP000069272    UP000000673    UP000076408    UP000075920    UP000069940    UP000249989    UP000007266    UP000075880    UP000030765    UP000075886    UP000075903    UP000075902    UP000076407    UP000075840    UP000007062    UP000215335    UP000002358    UP000183832    UP000008237    UP000005205    UP000078540    UP000053105    UP000009046    UP000078541    UP000053097    UP000279307    UP000000311    UP000078492    UP000036403    UP000242457    UP000076502    UP000078200    UP000192223    UP000092445    UP000091820    UP000092444    UP000015103    UP000053825    UP000005203    UP000092460    UP000092443    UP000078542    UP000007798    UP000008792    UP000007755    UP000268350    UP000001070    UP000001819    UP000008744    UP000095301    UP000192221   

PRIDE

H9J0B7    O61470    Q9U5Z8   

Pfam

PF01399   PCI        + More
PF08375   Rpn3_C

Interpro

IPR035267   PSMD3        + More
IPR013586   26S_Psome_reg_C       
IPR036390   WH_DNA-bd_sf       
IPR000717   PCI_dom       
IPR019734   TPR_repeat       

SUPFAM

SSF46785   SSF46785       

ProteinModelPortal

H9J0B7   A0A2A4JY67   A0A2H1X096   A0A1E1WF21   I4DK33   A0A194RD45   + More
S4PGF7   A0A212FA38   A0A0L7LEF5   A0A2P8XTW6   V5GN64   A0A0C5AST9   A0A1B0DLH7   A0A2J7QBQ9   A0A1B6DCY0   B0WCQ3   A0A182K3Q3   A0A1Q3FAL3   A0A1B6FCJ6   N6THH0   A0A182R9S0   U4U1Q6   A0A067QNT9   A0A182MIP1   A0A182NEV7   A0A182PDF1   A0A023EU98   A0A2M4ADN7   Q16N14   A0A2M3ZH99   A0A182F5I5   W5JD00   A0A182YFG0   A0A182WGX4   A0A2M4BLH4   A0A182H859   U5EZB6   D6WL27   A0A182JBK4   A0A084VMC7   A0A182QVK3   A0A336KQ90   A0A1Y1MR71   A0A1L8DT32   A0A182VCR5   A0A182TT01   A0A182X2Y2   A0A182I4X2   O61470   A0A336K9E6   A0A232FC54   K7IPX0   A0A1J1I086   A0A0V0G3R3   A0A023FCV2   A0A069DU15   E2BQ36   A0A0P4VL30   A0A158NV98   A0A0A9Y084   A0A195B8F8   A0A0C9RE25   A0A0N0BHA9   E0VFN6   A0A195FV61   A0A026WTC0   E9IDJ2   E2AFJ6   A0A195ED72   A0A0K8WG40   A0A0J7L773   A0A034WS53   A0A2A3ET91   A0A154PIE7   A0A310SLR7   D3TN58   A0A1A9V9I3   A0A1W4XAH9   A0A1B0A540   A0A1A9W063   Q9U5Z8   A0A1B0G931   T1I033   A0A2R7W1Z7   A0A0L7RGT6   A0A088ASB8   W8C3L9   A0A1B0B7N7   A0A1A9XL20   A0A151IPB9   R4WQT4   B4N147   B4LS14   F4WNN9   A0A3B0JVU4   B4JAM3   Q29PI4   B4GKT7   A0A1I8MWP0   A0A1W4WA38  

PDB

6EPF     E-value=7.50328e-146,     Score=1327

KEGG

101746211    K03033 26S proteasome regulatory subunit N3 | (RefSeq) probable 26S proteasome non-ATPase regulatory

PATHWAY

03050    Proteasome - Bombyx mori (domestic silkworm)

GO

GO:0030234   GO:0042176   GO:0000502   GO:0006511   GO:0008541   GO:0008270   GO:0005838   GO:0005515   GO:0007155   GO:0016876   GO:0043039   GO:0004651   GO:0005634  

PANTHER

PTHR10758:SF2  

Length:

494

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.000990000000000002

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00198

outside

1  -  494

 

 

Pi

141.965908

Theta

172.770132

Tajima's D

-0.575928

CLR

666.897229

CSRT

0.223038848057597

Interpretation

Uncertain