SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO02023
Pre Gene Modal
BGIBMGA002952
Annotation
PREDICTED:_neural-cadherin_isoform_X4_[Bombyx_mori]
Full name
Neural-cadherin      
Alternative Name
Cadherin-N
Location in the cell
Cytoplasmic   Reliability : 1.881 Nuclear   Reliability : 1.775
 

Sequence

CDS
ATGACAGGCGCGATTTACGTAGCCGGCGCCCTTGATTACGAGACTAGGAAACGGTACGAGCTGAAGTTAGCGGCGTCCGACAACCTAAAGGAAAACTACACAACGGTGGTGATTCACGTGAAAGACGTCAATGACAACCCTCCAGTTTTCGAGCGACCTACGTACCGCACACAGATCACCGAGGAAGATGACCGCAATCTTCCAAAACGCGTTCTTCAGGTAACTGCAACCGACGGCGATAAAGATAGGCAGCAAAACATTGTCTATTTTCTGACTGGTCAAGGCATCGACCCAGACAATCCTGCAAACAGTAAATTCGACATTAATCGCACTACGGGAGAGATATTCGTATTAAAATCCTTGGATCGTGATCAACCAAATGGGCGACCGCAGTGGAGATTCACTGTATTTGCACAAGACGAAGGCGGTGAAGGACTCGTGGGCTACGCAGACGTTCAAGTTAATCTAAAAGATATTAATGATAATGCGCCTATTTTCCCTCAAGGCGTATACTTTGGTAATGTTACGGAAAATGGTACAGCTGGGATGGTTGTTATGACGATGACGGCTATAGATTACGATGATCCAGCTGAAAGTAATAATGCGAAGCTTTGGTACTCTATAGAAAAAAATGTTATTGAAGAAGAGACAGGATCGCCTATATTTGAGATCGAGCCAGAAACTGGTGTAATAAAAACTGCTGTCTGTTGTCTAGATCGAGAAAGAACCCCAGATTATTCAATTCAAATAGTAGCATCAGATGGAGGCGGTCTAAAAGGAACTGGTACAGCATCAATTAGAGTTAAGGACATAAATGATATGCCGCCTCAGTTTACTAAAGATGAATGGTTTACAGAAGTAGATGAAACAGACGGAACTAATTTACCAGAAATGCCCATCTTAACTGTGACCGTTCACGATGAAGATGAAACTAATAAATTTCAGTATAAAGTTATTGAAAATAGCGGTTATGGTGCTGATAAGTTTACTATGGTTAGGAATAATGACGGGACAGGTTCATTAAAAATTGTACAGCCTTTAGATTATGAAGACCAGTTACAGAGTAATGGTTTCAGGTTTAGAATACAAGTTAACGATAAAGGAGAAGATAATGACAATGATAAATATCATGTAGCTTATTCATGGGTTGTGGTTAAACTTAGAGATATAAACGACAATAAACCTCAATTTGAAAGAGCCAATATTGAAGTATCTGTGTACGAAAATGCAGAGGTGGGTAAAAGCTTAGAAACCTTTAAAGCAACTGATCCTGATCAAGGAGGAAAAAGCAAAGTATCTTACGCGATTGACAGATCGTCTGATAGGAAAAGACAATTTTCAATCAACCAAGAAGGAACTGTCAGTATACAAAGATCATTAGATAGGGAAGATACACCTCGACATCAAGTAAAAATTTTAGCTATAGACGATGGTGTTCCTCCACGAACAGCAACTGCTACTCTCACAGTTATTGTACAGGACATTAATGATAACGCACCGACATTTTTGAAAGATTATAGACCTGTTTTAACGGAACATATTACACCAAAAAAAGTAGCCGAGATTTTAGCTACAGATGACGATGACAGATCTAAAAGCAACGGTCCACCATTTCAATTTCGTCTAGATCCCGGTGCTGACGACATAATAAGAGCTTCTTTTAAAGTTGAACAAGATCAAAAAGGAGCAAATGGAGATGGCATGGCGATTGTTTCTTCACTACGTTCTTTTGATCGAGAGCAACAGAAGGAATATTTAATTCCCATAATCATCAAAGATCATGGGAATCCTGCTATGACTGGAACTAGTACTTTAACTGTAGTTATTGGAGATGTAAATGATAACAAGATGCAACCAGGTTCCAAAGACATCTTAGTGTATAGTTATCAAGGTCTGTCACCTGATACTGAAATTGGGCGTGTCTATGTATACGATTTAGATGATTGGGATTTGCCAGATAAAAAATTCTTCTGGGAAAATACTGAAAATCCGAATTTCACTTTAAACGAAGAAACTGGTATGATTACAATGAAACAAAAAACAAGAGAAGGAAGATACCATTTGAAATTCAAAGTATATGATAGAAAGCACACACAAACAGATGTGCCTGCAAACGTAACTGTTTACGTTAAGGAAATATCACATGAAGCCATAATAAACTCAGGTTCTATTAGAATATCTGGAATATCTGATGAAGATTTTATAAGAGTGTGGAATTATAAAACTCTCAGCGTTTCAAGAAGTAAATTAGACATATTCAAAGATAAATTAGCGGATCTTTTGAATACGGAAAGAGAAAATATAGATATATTTAGTGTTCAACTCAGGAAAAAACATCCACCCGTAACTGATATTCGATACGCTGCCCACGGAGCACATTATTATAAACCAGTAAGATTAAATGGTATTGTATTGATGCACAGAGAAGAGATTGAAAGGGCGGTCGGAATAAATATAACCATGGTCGGAATCGATGAATGTCTCTATGAAAATCAAATGTGCGAAGGTTCATGCACTAATACATTGGACATAAGCAGCTTACCCTACATGGTAAATGCAAATAAGACCGCTCTTGTTGGTGTGCGCGTTGATGTCATAGGACAGTGTACATGCGGTGCACGTAATTTTACTCAAGCTGAAACATGTCGCAATTCACCATGCTATAACGGCGGTAGGTGTATTGACGGAAAATATGGACTAACTTGTTCATGTCCACCTGGTTATACTGGGCCGCGATGTCAGCAAACGTCAAGGAGTTTCAGAGGAACGGGGTGGGCTTGGTACCCATCTCTAGAAATGTGTGATGATTCACATCTAAGTTTTGAATTTATAACAAGAAAGTCCGAAGGTGTTTTAATCTACAACGGACCCATTGTTCCACCTGAGTCCGAAGAAATCATGGTATCCGATTTCATATCTATAGAATTAGAAAGAGGCAATCCAAGATTGTTGATTGATTTCGGATCGGGTACCTTAGAATTAAGAGTGAAAGCAAAGAAATCTTTGGATGATGGAGAATGGCATCGAATCGATATATTTTGGGACACTGAAAACGTAAGAATGATTGTAGACTATTGTAAATCAGCTGATATCCAAGAAATGGAAGATGGCACTCCACCCGAATTCGACGATTCTACATGTCAAGCAACTGGGACGATTCCTCCATTCAATGAATATTTAAATGTAAATGCTCCACTTCAAGTCGGTGGTTTATATATAGAACACTTTGACCCTACACATTATCACTGGCAGTATATGCCAATCGGCAAAGGATTTGACGGATGTATTCGTAATTTGATCCATAACAGTAAACTGTATGATTTAGCTCATCCGGGTCTTTCTCGAAATTCAGTAGCAGGATGCCCACAGACAGAGGAAGTGTGTAATCAAGCTGATACAACATCTAGATGCTGGGAGCACGGAACTTGTGTTGGGAGTTTTTCGGAAGCGAGATGTCAATGTCAGCCAGGTTGGACTGGTCCTTCGTGCAATTTACCAACAACGCCCACCAGTTTCAGACCCCAAAGCTATGTAAAATTTGCTTTAAGTTTCGAACCGGACCGATTTAGTACACAGATTCAGTTGCGTTTTAGAACACGGGAGCCTCACGGTGAATTATTCAGAGTGAGCGATCAACACAACCGCGAATATGGAATATTGGAAGTAAAAGACGCTCGTCTACATTTCCGATATAACCTTAATTCCTTGAGAACCGAAGAACGTGATGTGTGGTTAAATTCTGTCGCTGTCGATGATGGCCAATGGCACATTGCTCGGGTCAGTAGATATGGAAGTGCTGCGACACTAGAGATAGATGGCGGTGAGGGACGACGGTACAACGAAACATTTACATTTGAAGGTCATCAGTGGCTTCTTGTAGATAAACAAGAAGGTGTTTACGCTGGCGGAAAAGCCGAATACACTGGAGTGAGAACCTTTGAAGTATATGCCGATTTCCAAAAAGGTTGCTTGGATGATATAAGATTGGAAGGAAAACATTTACCTTTGCCGCCGGCTATGAATGGAACGCAGTGGGGTCAAGCAACAATGGCCCGTAATCTCGACCGCAATTGTCCTTCAAACAGTCCTTGCATTAACGTGCACTGTACGGAACCCTTTGTATGCGTCGATCTGTGGAACGAATACGAATGCACTTGCGGTGAGGGTTTGACTTTAACATCAGACTCAAAGAATTGCATTGACAAGAACGAGTGTCTCTACTTCCCTTGTCGCAACGGAGGCTCTTGCGTCAATCGCGAGCCGGGCTACCGTTGTCACTGCCCGGAAGGGTTCTGGGGCGAGAACTGCGAGCTCGTACAAGAAGGTCGCACTTTGAAACTCAGCATGGGAGCGCTGGCAGCCATCCTCGTCTGCCTTCTCATTATAATGATATTGGTGTTGGTATTCGTGGTGTATAATCGACGTCGCGAGGCACATATCAAGTACCCCGGTCCTGATGATGACGTTCGCGAGAACATCATTAACTACGATGACGAAGGTGGCGGTGAAGACGATATGACCGCTTTCGATATCACCCCTCTGCAGATACCGATTGGAGGACCTCTGCCCGATCACGCACCCGCTAAACTACCATATCCATTGATAGGCGTTGGCTTAGGCGTTGGTCCAATTGGCGTTGGAGTGGGGGTGCCTCCCGGTGTTGGGATGCCGATGCCCGGCGAAACCAACGTTGGTCTGTTCATCGAGGAACACAAACGGCGCGCTGACAGTGACCCTAACGCACCGCCCTTCGACGATCTGCGTAACTACGCTTACGAAGGCGGCGGCAGCACTGCTGGATCATTATCCTCGCTCGCTTCTGGCACCGACGACGAGGCCCACGACTACGACTACCTGGGGGCCTGGGGTCCGAGGTTCGACAAACTCGCCGATCTGTACGGGCCCGACCTCGACGAGCAACTGTAA
Protein
MTGAIYVAGALDYETRKRYELKLAASDNLKENYTTVVIHVKDVNDNPPVFERPTYRTQITEEDDRNLPKRVLQVTATDGDKDRQQNIVYFLTGQGIDPDNPANSKFDINRTTGEIFVLKSLDRDQPNGRPQWRFTVFAQDEGGEGLVGYADVQVNLKDINDNAPIFPQGVYFGNVTENGTAGMVVMTMTAIDYDDPAESNNAKLWYSIEKNVIEEETGSPIFEIEPETGVIKTAVCCLDRERTPDYSIQIVASDGGGLKGTGTASIRVKDINDMPPQFTKDEWFTEVDETDGTNLPEMPILTVTVHDEDETNKFQYKVIENSGYGADKFTMVRNNDGTGSLKIVQPLDYEDQLQSNGFRFRIQVNDKGEDNDNDKYHVAYSWVVVKLRDINDNKPQFERANIEVSVYENAEVGKSLETFKATDPDQGGKSKVSYAIDRSSDRKRQFSINQEGTVSIQRSLDREDTPRHQVKILAIDDGVPPRTATATLTVIVQDINDNAPTFLKDYRPVLTEHITPKKVAEILATDDDDRSKSNGPPFQFRLDPGADDIIRASFKVEQDQKGANGDGMAIVSSLRSFDREQQKEYLIPIIIKDHGNPAMTGTSTLTVVIGDVNDNKMQPGSKDILVYSYQGLSPDTEIGRVYVYDLDDWDLPDKKFFWENTENPNFTLNEETGMITMKQKTREGRYHLKFKVYDRKHTQTDVPANVTVYVKEISHEAIINSGSIRISGISDEDFIRVWNYKTLSVSRSKLDIFKDKLADLLNTERENIDIFSVQLRKKHPPVTDIRYAAHGAHYYKPVRLNGIVLMHREEIERAVGINITMVGIDECLYENQMCEGSCTNTLDISSLPYMVNANKTALVGVRVDVIGQCTCGARNFTQAETCRNSPCYNGGRCIDGKYGLTCSCPPGYTGPRCQQTSRSFRGTGWAWYPSLEMCDDSHLSFEFITRKSEGVLIYNGPIVPPESEEIMVSDFISIELERGNPRLLIDFGSGTLELRVKAKKSLDDGEWHRIDIFWDTENVRMIVDYCKSADIQEMEDGTPPEFDDSTCQATGTIPPFNEYLNVNAPLQVGGLYIEHFDPTHYHWQYMPIGKGFDGCIRNLIHNSKLYDLAHPGLSRNSVAGCPQTEEVCNQADTTSRCWEHGTCVGSFSEARCQCQPGWTGPSCNLPTTPTSFRPQSYVKFALSFEPDRFSTQIQLRFRTREPHGELFRVSDQHNREYGILEVKDARLHFRYNLNSLRTEERDVWLNSVAVDDGQWHIARVSRYGSAATLEIDGGEGRRYNETFTFEGHQWLLVDKQEGVYAGGKAEYTGVRTFEVYADFQKGCLDDIRLEGKHLPLPPAMNGTQWGQATMARNLDRNCPSNSPCINVHCTEPFVCVDLWNEYECTCGEGLTLTSDSKNCIDKNECLYFPCRNGGSCVNREPGYRCHCPEGFWGENCELVQEGRTLKLSMGALAAILVCLLIIMILVLVFVVYNRRREAHIKYPGPDDDVRENIINYDDEGGGEDDMTAFDITPLQIPIGGPLPDHAPAKLPYPLIGVGLGVGPIGVGVGVPPGVGMPMPGETNVGLFIEEHKRRADSDPNAPPFDDLRNYAYEGGGSTAGSLSSLASGTDDEAHDYDYLGAWGPRFDKLADLYGPDLDEQL

Summary

Description
Cadherins are calcium-dependent cell adhesion proteins.
Keywords
3D-structure   Alternative splicing   Calcium   Cell adhesion   Cell membrane   Complete proteome   Disulfide bond   EGF-like domain   Glycoprotein   Membrane   Metal-binding   Reference proteome   Repeat   Signal   Transmembrane   Transmembrane helix  
Feature
chain  Neural-cadherin
splice variant  In isoform A, isoform C, isoform E and isoform G.
EMBL
BABH01010605    BABH01010606    ODYU01012450    SOQ58761.1    KQ459601    KPI93771.1    + More
AGBW02012383    OWR45146.1    MF741662    AVD96945.1    KQ460597    KPJ13829.1    JTDY01001441    KOB73853.1    KK852860    KDR14826.1    CH940649    EDW64865.2    AB002397    AE014134    KRF81899.1    AAZ66476.1    CM000158    KRJ98980.1    EDW90155.2    KRJ98977.1    KRJ98978.1    CH477197    EAT48357.1    CH902620    EDV30907.1    KPU73116.1    CH379060    EDY70333.1    OUUW01000004    SPP80017.1    KRT04495.1    KRT04500.1    KRT04501.1    SPP80014.1    CH933807    EDW12917.2    KRJ98976.1    UFQT01000236    SSX22198.1    GEDC01004966    JAS32332.1    KPU73114.1    CH963913    EDW77290.2    CVRI01000058    CRL02734.1    CH916368    EDW04131.1    GEDC01012884    JAS24414.1    AAAB01008980    EAU76028.2    ATLV01027002    ATLV01027003    KE525421    KFB53759.1    KQ977649    KYN00796.1    GBHO01025976    JAG17628.1    GECZ01001915    JAS67854.1    KQ976745    KYM75525.1    ADTU01024158    ADTU01024159    ADTU01024160    ADTU01024161    ADTU01024162    ADTU01024163    ADTU01024164    CH954179    KQS61959.1    GBHO01025977    JAG17627.1    KRJ98972.1    KRJ98973.1    KK107575    EZA48722.1    KPU73115.1    AAZ66475.1    GDHF01015429    JAI36885.1    KQ980487    KYN15876.1    GL450531    EFN80862.1    KRT04499.1    KRT04496.1    KRT04494.1    GDHF01010462    JAI41852.1    KRJ98979.1    CH480822    EDW55585.1    SPP80015.1    AAZ66474.1    SPP80012.1    KRJ98974.1    NNAY01000531    OXU27845.1    KQ981931    KYN32817.1    CCAG010016562    KRT04503.1    KRT04502.1    KRT04497.1    JXJN01001658    JXJN01001659    GBYB01006626    JAG76393.1    KQ971343    KYB27320.1    GEDC01001941    JAS35357.1    QOIP01000011    RLU17058.1    SSX22199.1    KQ414621    KOC67626.1    GDHF01021146    JAI31168.1    GL441313    EFN64925.1    GL887844    EGI69775.1    CRL02733.1    GBHO01040813    JAG02791.1    KRJ98975.1    AAZ66473.1    KRJ98981.1    GBHO01040805    JAG02799.1   
Pfam
PF01049   Cadherin_C        + More
PF02210   Laminin_G_2
PF00028   Cadherin
PF12661   hEGF
PF00008   EGF
Interpro
IPR001791   Laminin_G        + More
IPR000742   EGF-like_dom       
IPR013032   EGF-like_CS       
IPR018097   EGF_Ca-bd_CS       
IPR002126   Cadherin-like_dom       
IPR027397   Catenin_binding_dom_sf       
IPR000152   EGF-type_Asp/Asn_hydroxyl_site       
IPR013320   ConA-like_dom_sf       
IPR020894   Cadherin_CS       
IPR015919   Cadherin-like_sf       
IPR001881   EGF-like_Ca-bd_dom       
IPR000233   Cadherin_cytoplasmic-dom       
IPR009030   Growth_fac_rcpt_cys_sf       
SUPFAM
SSF57184   SSF57184        + More
SSF49899   SSF49899       
SSF49313   SSF49313       
Gene 3D
PDB
3Q2W     E-value=3.23459e-41,     Score=429

Ontologies

Topology

Subcellular location
Cell membrane  
Length:
1641
Number of predicted TMHs:
1
Exp number of AAs in TMHs:
37.3754
Exp number, first 60 AAs:
0
Total prob of N-in:
0.00016
outside
1  -  1449
TMhelix
1450  -  1472
inside
1473  -  1641
 
 

Population Genetic Test Statistics

Pi
253.397504
Theta
201.938359
Tajima's D
0.81998
CLR
0.402087
CSRT
0.615219239038048
Interpretation
Possibly Positive selection
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