Gene

KWMTBOMO02018  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA002950

Annotation

PREDICTED:_neural-cadherin_isoform_X2_[Bombyx_mori]

Location

Bomo_Chr4(+):10287581-10318936      View in EpiBrowser

Full name

Neural-cadherin      

Alternative Name

Cadherin-N

Location in the cell

Cytoplasmic   Reliability : 1.895 Nuclear   Reliability : 1.567

CDS

ATGCAGACTGTAGTGCAGCTGAATGCTGCTCCAAACACACCAGTCTTCACGCTTCAAGCCAGGGACCCTGACTCCGACCATAATATCCATTACTTCATCGTTCGAGACAGAACCGGTGGAAGATTCGAAGTCGACGAGAGATCCGGAGTCGTCCGTACCAGAGGGACCGACCCGTTTCAACTTGACATGGAGTACGTGCTTTACGTCAAAGCGGAGGATCAGAATGGTCGTGTCGACGAAAGGAGGTTTCAGTCAACTCCCGAAGAACGTCTCAGCATCGTCGGCGGAAAGCGAGCTCCGCAGTTCTATTTGCCGAGTTACGAAGCTGAAATCGCAGAGAACCAGAAAAAAGATTCCGATATAATATCAGTGAAAGCCAAGTCGTTTGCTGATCGCGAAATCCGGTACACGCTCAAGGCACAAGGTCAAGGCGCCGGAACGTTCAACATTGGCCCAACATCGGGTATTGTCAAGTTGGCCAAGGAGCTGGATTTTGAAGATCTACGGCAACCGCATGTTTATTCTCTCGTCGTCACCGCTACGGAAGATTCAGGCGGTTTCTCTACTTCTGTTGAGCTAACAATTAGAGTAACCGACGTAAATGACAACGCTCCGAAGTTTGAGTTGCCAGATTATCAAGCCCACAATGTTGATGAAGATATACCTCTTGGCACCAGCATTCTCAAGGTCAAGGCTATGGATGCTGATTCCGGAAAAAACGCTGAGATCGAATATCTGGTTTCAGATGACCACTTCAGCGTCGATTCGAACGGCATAATCACCAATAACAAACTACTGGATGCTGACAACAATAACGCTTATTACGAATTTGTAGTCACAGCGAAAGATAAGGGCGAACCCGCTAAAACTGGAACGGCTACCGTCCGAGTTTATACGAAGAATAAGAACGACGAGGAACCAAAATTCTCTCAACAAGTTTACACTCCGAATGTAGACGAAAACGCAGGACCGAACACCTTAGTCACGACCGTAGTCGCTTCGGATAAAGACGGCGACAACGTGAGGTTTGGTTTTGTTGGAGGCGGTACAAGTTCAGGTCAATTTGTCATAGAAGAAATAACTGGTGTTATCCGACTGCACAATAAAGCTATCTCATTAGACCGTGACAAATACGAACTGAACGTGACCGCTATGGACGACGGCGCTTGTTGTGTTAACGGTGACGCCACTATACACACCTCCACGGCTGTAGTGGTCGTATTTATAACAGACGTGAACGACAATAAACCTATATTCAAAGATTGTCCAACTTACTTTCCGAAAGTAGAAGAGGGCGCGCCTAATGGGAGTCCCGTTATAAAGGTGCACGCCACCGACGAGGACAAAGGTGTTAACGGTCAAGTAAAATATTCTATAGTGCAACAGCCCAATCAGAAAGGAACAAAGTTCACGGTGGACGAAGAAACAGGTGAAGTGTCGACGAACAAAGTTTTCGATCGCGAAGGCGACGACGGTAAATTCGTATCGGTAACGGTAAAGGCAACCGATCAGGGCGAACCTTCTTTAGAAGGCGTGTGTTCATTCACTGTTGAGATTACCGATGTCAACGACAACCCTCCGCTCTTTGACCGTCAAAAATATGTGGAGAATGTCAAACAAGATGCCAGTATTGGCACAAACATATTAAGAGTTTCGGCATCTGACGAGGACGCTGATAATAACGGCGCTATTGTTTACACACTGAGTTCCCCGTACAATCTTGCCGACATTGAATATTTTGAAATCCAGCCCGAGTCGGGCTGGATCGTTCTTAAAAAACCACTCGACCGAGAAACTTACAAGTTGGAGGCTATGGCTCAAGACAAGGGTTTCCCGCCCTTGTCCCGAACCGTGGAGGTCCAGATAGACGTAGTGGATCGCGCGAACAATCCCCCCGTGTGGGACCACGTGGTGTACGGCCCGATCTACATTCGAGAGAATTTGCCCGTGGGTGCCAAAGTGGTGTCCGTGAAAGCAAGTTCCGGAATCGAGAACAACCCTACGGTGTTCTACAGACTGATGCCGGGGTCAACTGCGCAAACCAATAAATTCCACACGTTTTACCTCCAGCAGAGGGCCGACAATGGTAACACGTGGGCGGATATTAAAGTAAACCATCCTTTGGATTACGAAAGCATTAAAGAGTACAACTTAACGATCAGAGTTGAGAACAACGGTGCGCAACAACTGGCTTCAGAAGCGACTGTCTACATCATGTTAGAAGACGTCAACGATGAAATTCCTCTGTTTACTGAACGAGAGCAAGAGACCGTGCTGGAAGGAGAGCCGATTGGTACCAAGGTCACCCAGGTCAACGCTATCGACAAAGATGGAACATTCCCGAATAATCAGGTGTACTACTATATAGTGGACTCACCTCGCAATGAAGGGAAAGACTTCTTCGAGATCAGCATGCAGACCGGCGAGATCTTCACTAAGGTGGTGTTCGACAGGGAGAAGCAGGGCGCCTACGCTTTAGAAGTGGAGGCGAGGGATGGCGCACCATCGGCGCGGCCTAACTCAGACAACCAGCCCAACTCAGCCACTGTCACCATTTAA

Protein

MQTVVQLNAAPNTPVFTLQARDPDSDHNIHYFIVRDRTGGRFEVDERSGVVRTRGTDPFQLDMEYVLYVKAEDQNGRVDERRFQSTPEERLSIVGGKRAPQFYLPSYEAEIAENQKKDSDIISVKAKSFADREIRYTLKAQGQGAGTFNIGPTSGIVKLAKELDFEDLRQPHVYSLVVTATEDSGGFSTSVELTIRVTDVNDNAPKFELPDYQAHNVDEDIPLGTSILKVKAMDADSGKNAEIEYLVSDDHFSVDSNGIITNNKLLDADNNNAYYEFVVTAKDKGEPAKTGTATVRVYTKNKNDEEPKFSQQVYTPNVDENAGPNTLVTTVVASDKDGDNVRFGFVGGGTSSGQFVIEEITGVIRLHNKAISLDRDKYELNVTAMDDGACCVNGDATIHTSTAVVVVFITDVNDNKPIFKDCPTYFPKVEEGAPNGSPVIKVHATDEDKGVNGQVKYSIVQQPNQKGTKFTVDEETGEVSTNKVFDREGDDGKFVSVTVKATDQGEPSLEGVCSFTVEITDVNDNPPLFDRQKYVENVKQDASIGTNILRVSASDEDADNNGAIVYTLSSPYNLADIEYFEIQPESGWIVLKKPLDRETYKLEAMAQDKGFPPLSRTVEVQIDVVDRANNPPVWDHVVYGPIYIRENLPVGAKVVSVKASSGIENNPTVFYRLMPGSTAQTNKFHTFYLQQRADNGNTWADIKVNHPLDYESIKEYNLTIRVENNGAQQLASEATVYIMLEDVNDEIPLFTEREQETVLEGEPIGTKVTQVNAIDKDGTFPNNQVYYYIVDSPRNEGKDFFEISMQTGEIFTKVVFDREKQGAYALEVEARDGAPSARPNSDNQPNSATVTI

Description

Cadherins are calcium-dependent cell adhesion proteins.

Keywords

3D-structure   Alternative splicing   Calcium   Cell adhesion   Cell membrane   Complete proteome   Disulfide bond   EGF-like domain   Glycoprotein   Membrane   Metal-binding   Reference proteome   Repeat   Signal   Transmembrane   Transmembrane helix  

Feature

chain  Neural-cadherin
splice variant  In isoform A, isoform C, isoform E and isoform G.

Uniprot

A0A2C9GQ24   A0A2A4J0P4   A0A1I8PL40   A0A0Q9WB21   W8AWR8   A0A0K8UX95   + More
B3MMG1   A0A0P8XUW0   B4LSV4   A0A1W4W5J8   A0A1W4VUC2   A0A1W4VU89   A0A0R3P0Q4   O15943-3   A0A1W4W6A0   A0A3B0JCB5   A0A0R1DPS1   O15943   A0A3B0K333   A0A3B0JD75   A0A0R3NYQ3   O15943-8   B4I5C9   B4P8P7   O15943-6   A0A0R3NTE6   A0A0R1DNX3   A0A0R3NU79   A0A0R1DR17   U4UTI7   N6ULT8   A0A2S2Q0Y3   A0A2H8TLY4   A0A2S2QZQ2   B4GQ93   H9J0B4   A0A2C9GQ21   A0A3F2YZM9   A0A158NRP6   A0A224X4K9   A0NFT6   A0A1I8PKY1   A0A0K8VEB9   A0A0K8VSJ4   A0A1I8PL58   A0A0R3NTF8   B5DJ41   A0A0R3P032   A0A0R3NTR0   A0A3B0JCC7   A0A3B0JH23   A0A1W4W6T6   A0A1W4W5G9   A0A1W4W5I8   A0A1W4VUD5   O15943-7   O15943-5   O15943-2   O15943-4   A0A0R1DV97   A0A0R1DNY4   A0A0R1DP25   A0A0R1DNR9   A0A0R3NTR2   A0A0R3NTY0   A0A0Q9WM48   A0A0R3NZP2   A0A0R3NYZ3   A0A3B0JI81   A0A1W4VU58   A0A1W4W654   A0A1W4VU66   A0A1W4W674   Q4ABF0   A0A0Q5VKI2   Q4ABE7   A0A0J9R4T8   Q4ABE9   Q4ABE8   A0A1B6E320   A0A1B6EBT5   A0A195DSI5   A0A232FAH0   E9HD90   A0A0N8DFA2   A0A0P5MU13   A0A0P5KUE9   A0A0P6D4G7   A0A0P6EF30   A0A0P5VN86   A0A0P6D9N4   A0A0P6EG73   A0A0P5NFT2   A0A0P5MYD4   A0A0P5CPY5   A0A0P5MUG8   A0A0N8BPK8   A0A0K8U3L7   V9IF67   Q5CCS5  

Pubmed

17994087    24495485    18057021    15632085    9247265    10731132    + More
12537572    9635189    17550304    23537049    19121390    21347285    12364791    23185243    12537568    12537573    12537574    16110336    17569856    17569867    22936249    28648823    21292972    16174032   

EMBL

NWSH01004035    PCG65551.1    CH940649    KRF81900.1    GAMC01017322    JAB89233.1    + More
GDHF01021146    JAI31168.1    CH902620    EDV30907.1    KPU73116.1    KPU73115.1    EDW64865.2    CH379060    KRT04502.1    AB002397    AE014134    OUUW01000004    SPP80017.1    CM000158    KRJ98974.1    SPP80016.1    SPP80015.1    KRT04495.1    CH480822    EDW55585.1    EDW90155.2    KRJ98977.1    KRJ98978.1    KRT04494.1    KRJ98981.1    KRT04492.1    KRJ98973.1    KB632358    ERL93501.1    APGK01027544    APGK01027545    APGK01027546    APGK01027547    KB740664    ENN79672.1    GGMS01002222    MBY71425.1    GFXV01002493    MBW14298.1    GGMS01014035    MBY83238.1    CH479187    EDW39765.1    BABH01010620    ADTU01024150    ADTU01024151    ADTU01024152    GFTR01008979    JAW07447.1    AAAB01008980    EAU76025.2    GDHF01015429    JAI36885.1    GDHF01010462    JAI41852.1    KRT04497.1    EDY70333.1    KRT04499.1    KRT04498.1    SPP80014.1    SPP80013.1    KRJ98979.1    KRJ98972.1    KRJ98980.1    KRJ98975.1    KRT04503.1    KRT04500.1    KRT04501.1    KRF81899.1    KRT04496.1    KRT04493.1    SPP80012.1    AAZ66474.1    CH954179    KQS61959.1    AAZ66476.1    CM002910    KMY90739.1    AAZ66473.1    AAZ66475.1    GEDC01004966    JAS32332.1    GEDC01001941    JAS35357.1    KQ980487    KYN15880.1    NNAY01000531    OXU27844.1    GL732622    EFX70325.1    GDIP01039431    JAM64284.1    GDIQ01159298    JAK92427.1    GDIQ01179086    JAK72639.1    GDIQ01082878    JAN11859.1    GDIQ01064782    JAN29955.1    GDIP01112219    JAL91495.1    GDIQ01081373    JAN13364.1    GDIQ01063232    JAN31505.1    GDIQ01143053    JAL08673.1    GDIQ01160895    JAK90830.1    GDIP01183109    JAJ40293.1    GDIQ01162495    JAK89230.1    GDIQ01157395    JAK94330.1    GDHF01031156    JAI21158.1    JR040371    AEY59106.1    AB190300    BAD91055.1   

Proteomes

UP000218220    UP000095300    UP000008792    UP000007801    UP000192221    UP000001819    + More
UP000000803    UP000268350    UP000002282    UP000001292    UP000030742    UP000019118    UP000008744    UP000005204    UP000075902    UP000005205    UP000007062    UP000008711    UP000078492    UP000215335    UP000000305   

PRIDE

O15943    H9J0B4    Q4ABF0    Q4ABE7    Q4ABE9    Q4ABE8    + More

Pfam

PF00028   Cadherin        + More
PF00008   EGF
PF01049   Cadherin_C
PF02210   Laminin_G_2
PF12661   hEGF

Interpro

IPR002126   Cadherin-like_dom        + More
IPR015919   Cadherin-like_sf       
IPR020894   Cadherin_CS       
IPR013032   EGF-like_CS       
IPR000742   EGF-like_dom       
IPR001791   Laminin_G       
IPR009030   Growth_fac_rcpt_cys_sf       
IPR000233   Cadherin_cytoplasmic-dom       
IPR001881   EGF-like_Ca-bd_dom       
IPR013320   ConA-like_dom_sf       
IPR027397   Catenin_binding_dom_sf       
IPR000152   EGF-type_Asp/Asn_hydroxyl_site       
IPR018097   EGF_Ca-bd_CS       

SUPFAM

SSF49313   SSF49313        + More
SSF57184   SSF57184       
SSF49899   SSF49899       

Gene 3D

4.10.900.10    

ProteinModelPortal

A0A2C9GQ24   A0A2A4J0P4   A0A1I8PL40   A0A0Q9WB21   W8AWR8   A0A0K8UX95   + More
B3MMG1   A0A0P8XUW0   B4LSV4   A0A1W4W5J8   A0A1W4VUC2   A0A1W4VU89   A0A0R3P0Q4   O15943-3   A0A1W4W6A0   A0A3B0JCB5   A0A0R1DPS1   O15943   A0A3B0K333   A0A3B0JD75   A0A0R3NYQ3   O15943-8   B4I5C9   B4P8P7   O15943-6   A0A0R3NTE6   A0A0R1DNX3   A0A0R3NU79   A0A0R1DR17   U4UTI7   N6ULT8   A0A2S2Q0Y3   A0A2H8TLY4   A0A2S2QZQ2   B4GQ93   H9J0B4   A0A2C9GQ21   A0A3F2YZM9   A0A158NRP6   A0A224X4K9   A0NFT6   A0A1I8PKY1   A0A0K8VEB9   A0A0K8VSJ4   A0A1I8PL58   A0A0R3NTF8   B5DJ41   A0A0R3P032   A0A0R3NTR0   A0A3B0JCC7   A0A3B0JH23   A0A1W4W6T6   A0A1W4W5G9   A0A1W4W5I8   A0A1W4VUD5   O15943-7   O15943-5   O15943-2   O15943-4   A0A0R1DV97   A0A0R1DNY4   A0A0R1DP25   A0A0R1DNR9   A0A0R3NTR2   A0A0R3NTY0   A0A0Q9WM48   A0A0R3NZP2   A0A0R3NYZ3   A0A3B0JI81   A0A1W4VU58   A0A1W4W654   A0A1W4VU66   A0A1W4W674   Q4ABF0   A0A0Q5VKI2   Q4ABE7   A0A0J9R4T8   Q4ABE9   Q4ABE8   A0A1B6E320   A0A1B6EBT5   A0A195DSI5   A0A232FAH0   E9HD90   A0A0N8DFA2   A0A0P5MU13   A0A0P5KUE9   A0A0P6D4G7   A0A0P6EF30   A0A0P5VN86   A0A0P6D9N4   A0A0P6EG73   A0A0P5NFT2   A0A0P5MYD4   A0A0P5CPY5   A0A0P5MUG8   A0A0N8BPK8   A0A0K8U3L7   V9IF67   Q5CCS5  

PDB

3UBH     E-value=8.08959e-147,     Score=1337

KEGG

100134924    no KO assigned | (RefSeq) 2cad; cadherin-2

GO

GO:0007156   GO:0005886   GO:0005509   GO:0016021   GO:0045467   GO:0042803   GO:0007412   GO:0005887   GO:0007411   GO:0007413   GO:0048841   GO:0030424   GO:0030425   GO:0005911   GO:0031290   GO:0048814   GO:0048846   GO:0050774   GO:0016318   GO:0016339   GO:0048675   GO:0008013   GO:0045463   GO:0044331   GO:0045296   GO:0016020   GO:0007155   GO:0005737   GO:0016876   GO:0043039   GO:0004651   GO:0005634  

Subcellular location

Cell membrane  

Length:

852

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00128

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00012

outside

1  -  852

 

 

Pi

25.260192

Theta

189.708151

Tajima's D

0.571963

CLR

0.525264

CSRT

0.530723463826809

Interpretation

Uncertain