Gene

KWMTBOMO02017

Pre Gene Modal

BGIBMGA002949

Annotation

PREDICTED:_neural-cadherin_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr4(+):10232736-10235130      View in EpiBrowser

Full name

Neural-cadherin      

Alternative Name

Cadherin-N

Location in the cell

Cytoplasmic   Reliability : 1.984

CDS

ATGACGCACACCGTGCTGGCGGGAGGAGCACTGCTGTACGCCTTGAGCATAGTGATGCAGGCGGGTGCCCTCACCCTGTTGCCACACGATGTACACCCTGGACATGCTGTTCGGCATTTTGTCGGCAACCATTCCCGATATACGCTACTTGACCCTGAATTCACATCTTATTTCACTTTACTCGACAACGGACTTTTAATGACCACAGCTGATTTGTCTCCGTTACTAAATCAACCTATAGATCTTGCGATATTAGAACAGACGCCTTACAGCAGTGCAGCGCATTCTGTTCATATATTTGTGATGGATCGTAGAAGGATGCTACATTTCACACCGAGTGAAGGCGTGAGTGGAGAAATACCAGAAAATGCGCCACCGGGAACTATAGTAGACGTGCCTCTTATAAAAGCCACGGCCCTAGTAGATGTCGGGCCCATAGCATACAAAATTATAAAAGGCGATGAAGATGCCGTATTCACATTACGGGCTAAAGGTAATAGAGATTTAAATACAGACGTAAGATCAGTAATCACCGATGGAGATGTCGAGATAGTTTCGATTAAACCTTTAGATACTGAACAAAAGAGTATATACAATTTGAATATACAAGCAACTGATATTCATGGCACAAGCAAAGCCATTTTACCTGTGAAAATCGAAGTTTTGAATGAAAATGATCACGAACCGCGTTTTGAACAAGAATTTTATTATTTTGTTGTGAGCGGGACTCAAGATGAAAATGCACCTAACGGTACGGCTCGATGGCAGAGGTTCTCAAAGATTGGCAAAGTGCATGCTTACGATGCTGATAAAGATCGAGTGTATTATACCCTAATGAACCCAAATAATTTGGCCGTTATAGTACCACAGACCGGAGAACTAATATTAGCAGGTGAACCTGACAGTAACGAGGTTGAATTGAAAGTTCTTGCTCACGACACGGGAGCGCCGCCGCGTGCAAGCAAACCGGCACGCGTTTTTATTGAGTTCGTGATTCGAGATAGAAAAGATTTACCAGCACTTCACCGTGAGAAGAGACGAGTCACTCGCGCAGTGCGACCTACGAAACGTATTGAATTCACGGAATCTGATGGAGAAGTTGAAGGGCGTGCCGTATTTACACTCGAAAAAGAAACTGACCGTGAAACCTTTAAAATTCGCGACGACAATCCGTGGGTTGCCGTTGAACCCAGTGGTGTAGTGAAAGTCAAAAAGAAGTGGGACTTCGAAGACTTGGGCCCTGAGAAGACCATCGACTTCTGGGTGACGATATCGAATGCTGGGAACGGAGGTGAGTCTAGATCGATATTTATTTAA

Protein

MTHTVLAGGALLYALSIVMQAGALTLLPHDVHPGHAVRHFVGNHSRYTLLDPEFTSYFTLLDNGLLMTTADLSPLLNQPIDLAILEQTPYSSAAHSVHIFVMDRRRMLHFTPSEGVSGEIPENAPPGTIVDVPLIKATALVDVGPIAYKIIKGDEDAVFTLRAKGNRDLNTDVRSVITDGDVEIVSIKPLDTEQKSIYNLNIQATDIHGTSKAILPVKIEVLNENDHEPRFEQEFYYFVVSGTQDENAPNGTARWQRFSKIGKVHAYDADKDRVYYTLMNPNNLAVIVPQTGELILAGEPDSNEVELKVLAHDTGAPPRASKPARVFIEFVIRDRKDLPALHREKRRVTRAVRPTKRIEFTESDGEVEGRAVFTLEKETDRETFKIRDDNPWVAVEPSGVVKVKKKWDFEDLGPEKTIDFWVTISNAGNGGESRSIFI

Description

Cadherins are calcium-dependent cell adhesion proteins.

Keywords

3D-structure   Alternative splicing   Calcium   Cell adhesion   Cell membrane   Complete proteome   Disulfide bond   EGF-like domain   Glycoprotein   Membrane   Metal-binding   Reference proteome   Repeat   Signal   Transmembrane   Transmembrane helix  

Feature

chain  Neural-cadherin
splice variant  In isoform A, isoform C, isoform E and isoform G.

Uniprot

H9J0B3   A0A2H1VLI3   A0A212ERS6   A0A0L7L0C3   A0A194PM09   A0A194RD40   + More
A0A2P8Z1X7   A0A067R647   A0A2R7X6G5   D6WML0   A0A182G9C2   A0A1B0DQX4   A0A2J7QBT6   A0A182XN61   A0A182KU64   A0A182V727   A0A2L1IQ91   B0X8X4   A0A182JYT1   A0A182WGG2   A0A0L0CL95   A0A336LCK1   A0A182QIW7   A0A182F100   A0A182RY55   A0A182PEM3   A0A182SZC1   A0A336L2Y6   A0A182NBN6   A0A182M0Y4   U4UK53   A0A182Y0L3   A0A0Q9XFP9   N6TNT8   A0A1B0GK63   A0A1A9WMG8   A0A1A9YBS4   A0A1B0AQ26   A0A1A9UJP3   B4K0E4   A0A3Q0IKK3   A0A0Q9WB21   D9PTW4   B4Q8C6   A0A1I8MXK7   A0A182IM24   A0A1B0A9M1   A0A0R1DPS1   A0A0R1DNR9   B4P8P7   A0A0R1DV97   A0A0R1DNX3   A0A0R1DNY4   A0A0R1DP25   A0A0R1DR17   B4LSV4   A0A0Q9WM48   B3MMG1   A0A1I8PKY1   A0A0P8XUW0   A0A1I8PL40   A0A084WU71   A0A1I8PL58   A0A0J9R4T8   B4I5C9   B4JC98   A0A1W4W5I8   A0A1W4VU58   A0A1W4VUD5   A0A1W4W5G9   A0A1W4W6T6   A0A1W4VU89   A0A1W4W674   A0A1W4W654   A0A1W4VUC2   A0NFT6   A0A1W4W6A0   A0A1W4VU66   A0A1W4W5J8   A0A0Q5VKI2   A0A3F2YZM9   B4GQ93   A0A0R3NU79   A0A0R3NTE6   O15943-2   A0A0R3NTR0   A0A0R3NYZ3   A0A0R3NZP2   A0A0R3P032   A0A0R3NYQ3   A0A0R3P0Q4   Q4ABF0   A0A0R3NTF8   O15943-3   A0A0R3NTR2   O15943   O15943-6   O15943-7   B5DJ41   Q4ABE9  

Pubmed

19121390    22118469    26227816    26354079    29403074    24845553    + More
18362917    19820115    26483478    20966253    29415259    26108605    23537049    25244985    17994087    25315136    17550304    18057021    24438588    22936249    12364791    15632085    9247265    10731132    12537572    9635189    12537568    12537573    12537574    16110336    17569856    17569867   

EMBL

BABH01010622    ODYU01003220    SOQ41683.1    AGBW02012969    OWR44151.1    JTDY01004004    + More
KOB68719.1    KQ459601    KPI93774.1    KQ460597    KPJ13826.1    PYGN01000236    PSN50509.1    KK852860    KDR14823.1    KK857523    PTY27261.1    KQ971343    EFA04582.2    JXUM01241554    KQ635244    KXJ62502.1    AJVK01008800    NEVH01016296    PNF26053.1    MF741663    AVD96946.1    DS232508    EDS42730.1    JRES01000237    KNC33070.1    UFQS01003086    UFQT01003086    SSX15154.1    SSX34531.1    AXCN02000683    UFQS01001776    UFQT01001776    SSX12306.1    SSX31757.1    AXCM01001170    KB632358    ERL93502.1    CH933807    KRG03486.1    APGK01027556    KB740664    ENN79673.1    AJWK01028391    JXJN01001653    CH916433    EDV90834.1    CH940649    KRF81900.1    BT125123    ADM07129.1    CM000361    EDX05336.1    CM000158    KRJ98974.1    KRJ98975.1    EDW90155.2    KRJ98977.1    KRJ98978.1    KRJ98979.1    KRJ98981.1    KRJ98972.1    KRJ98980.1    KRJ98973.1    EDW64865.2    KRF81899.1    CH902620    EDV30907.1    KPU73116.1    KPU73115.1    ATLV01027003    KE525421    KFB53765.1    CM002910    KMY90739.1    CH480822    EDW55585.1    CH916368    EDW04131.1    AAAB01008980    EAU76025.2    CH954179    KQS61959.1    CH479187    EDW39765.1    CH379060    KRT04492.1    KRT04494.1    AB002397    AE014134    KRT04498.1    KRT04493.1    KRT04496.1    KRT04499.1    KRT04495.1    KRT04502.1    AAZ66474.1    KRT04497.1    KRT04503.1    EDY70333.1    AAZ66473.1   

Proteomes

UP000005204    UP000007151    UP000037510    UP000053268    UP000053240    UP000245037    + More
UP000027135    UP000007266    UP000069940    UP000249989    UP000092462    UP000235965    UP000076407    UP000075882    UP000075903    UP000002320    UP000075881    UP000075920    UP000037069    UP000075886    UP000069272    UP000075900    UP000075885    UP000075901    UP000075884    UP000075883    UP000030742    UP000076408    UP000009192    UP000019118    UP000092461    UP000091820    UP000092443    UP000092460    UP000078200    UP000001070    UP000079169    UP000008792    UP000000304    UP000095301    UP000075880    UP000092445    UP000002282    UP000007801    UP000095300    UP000030765    UP000001292    UP000192221    UP000007062    UP000008711    UP000075902    UP000008744    UP000001819    UP000000803   

PRIDE

H9J0B3    D9PTW4    O15943    Q4ABF0    Q4ABE9   

Pfam

PF00028   Cadherin        + More
PF00008   EGF
PF01049   Cadherin_C
PF02210   Laminin_G_2
PF12661   hEGF

Interpro

IPR015919   Cadherin-like_sf        + More
IPR002126   Cadherin-like_dom       
IPR039808   Cadherin       
IPR020894   Cadherin_CS       
IPR027397   Catenin_binding_dom_sf       
IPR013032   EGF-like_CS       
IPR000742   EGF-like_dom       
IPR000233   Cadherin_cytoplasmic-dom       
IPR001881   EGF-like_Ca-bd_dom       
IPR001791   Laminin_G       
IPR013320   ConA-like_dom_sf       
IPR009030   Growth_fac_rcpt_cys_sf       
IPR000152   EGF-type_Asp/Asn_hydroxyl_site       

SUPFAM

SSF49313   SSF49313        + More
SSF57184   SSF57184       
SSF49899   SSF49899       

Gene 3D

4.10.900.10    

ProteinModelPortal

H9J0B3   A0A2H1VLI3   A0A212ERS6   A0A0L7L0C3   A0A194PM09   A0A194RD40   + More
A0A2P8Z1X7   A0A067R647   A0A2R7X6G5   D6WML0   A0A182G9C2   A0A1B0DQX4   A0A2J7QBT6   A0A182XN61   A0A182KU64   A0A182V727   A0A2L1IQ91   B0X8X4   A0A182JYT1   A0A182WGG2   A0A0L0CL95   A0A336LCK1   A0A182QIW7   A0A182F100   A0A182RY55   A0A182PEM3   A0A182SZC1   A0A336L2Y6   A0A182NBN6   A0A182M0Y4   U4UK53   A0A182Y0L3   A0A0Q9XFP9   N6TNT8   A0A1B0GK63   A0A1A9WMG8   A0A1A9YBS4   A0A1B0AQ26   A0A1A9UJP3   B4K0E4   A0A3Q0IKK3   A0A0Q9WB21   D9PTW4   B4Q8C6   A0A1I8MXK7   A0A182IM24   A0A1B0A9M1   A0A0R1DPS1   A0A0R1DNR9   B4P8P7   A0A0R1DV97   A0A0R1DNX3   A0A0R1DNY4   A0A0R1DP25   A0A0R1DR17   B4LSV4   A0A0Q9WM48   B3MMG1   A0A1I8PKY1   A0A0P8XUW0   A0A1I8PL40   A0A084WU71   A0A1I8PL58   A0A0J9R4T8   B4I5C9   B4JC98   A0A1W4W5I8   A0A1W4VU58   A0A1W4VUD5   A0A1W4W5G9   A0A1W4W6T6   A0A1W4VU89   A0A1W4W674   A0A1W4W654   A0A1W4VUC2   A0NFT6   A0A1W4W6A0   A0A1W4VU66   A0A1W4W5J8   A0A0Q5VKI2   A0A3F2YZM9   B4GQ93   A0A0R3NU79   A0A0R3NTE6   O15943-2   A0A0R3NTR0   A0A0R3NYZ3   A0A0R3NZP2   A0A0R3P032   A0A0R3NYQ3   A0A0R3P0Q4   Q4ABF0   A0A0R3NTF8   O15943-3   A0A0R3NTR2   O15943   O15943-6   O15943-7   B5DJ41   Q4ABE9  

PDB

3UBH     E-value=2.14847e-34,     Score=365

KEGG

100134924    no KO assigned | (RefSeq) 2cad; cadherin-2

GO

GO:0005509   GO:0007156   GO:0016021   GO:0016020   GO:0005886   GO:0031290   GO:0048814   GO:0030424   GO:0030425   GO:0005911   GO:0005887   GO:0007411   GO:0007413   GO:0048841   GO:0045467   GO:0042803   GO:0007412   GO:0045463   GO:0044331   GO:0045296   GO:0008013   GO:0048846   GO:0050774   GO:0016318   GO:0016339   GO:0048675   GO:0006412   GO:0005634   GO:0005737   GO:0016876   GO:0043039   GO:0004651  

PANTHER

PTHR24027  

Subcellular location

Cell membrane  

SignalP

Position:   1 - 23,         Likelihood:  0.785060

 

 

Length:

438

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

20.19181

Exp number, first 60 AAs:

20.14569

Total prob of N-in:

0.91381

POSSIBLE N-term signal

sequence

inside

1  -  4

TMhelix

5  -  27

outside

28  -  438

 

 

Pi

243.614394

Theta

168.688962

Tajima's D

-0.489635

CLR

2.410819

CSRT

0.246487675616219

Interpretation

Uncertain