Gene

KWMTBOMO02007

Annotation

Nuclear_fragile_X_mental_retardation-interacting_protein_1_[Papilio_xuthus]

Location

Bomo_Chr4(-):9816383-9819212      View in EpiBrowser

Full name

Mediator of RNA polymerase II transcription subunit 11      

Alternative Name

Mediator complex subunit 11

Location in the cell

Nuclear   Reliability : 4.761

CDS

ATGAACCCTATTGAATTAAGTAGGTATATACCGCAGTCTCCAAGAATGCCGAACTATCCACGATTTTGTTTTCCGAATACTCAATGGCGATTCAACTATGGCCCACGTGTGTCTTCTTGGTCGAATCAAACCCAATCCATTATTGATAGAAATGAAGAACATTGGTGTGAAACTTGTGATAGAGGATTTCCTAATGCAGTCATTCTGGAGAAACATAAAAATCAACATGAAAAATGCAATATAGATGGATGCGGATTTGTAGCACATCCAAAGATAATAACCAAACACATACAAATGCAGCACTCGACTGGTCTTTACAAAAAAATTGCTAAATTAAATAATCCAGAGGAAATAAAGACATGGCGAGAAGATAGAAGAAGAAACTATCCAACACAAGCTAATATTGAGAAAAAAGCTGCAATGGTTAGGGAGAAAATTGAAAGAGGTGAAAAAATGGGACTTTCAAGAGACAAGAATATGTGTGACAATAAAAAATCAGGTATGAACAGAAAATACAAAAGTGATAATAGGAAATTCAATAACAAATGTGAACTAAATAGAAGAAAACCAATTGAACAAAAATTTAAAGCAAATCAGAAACCTTCCCAAACACCATTTAAAAAAACAAAAGTTCTACCAGTTCTTGATGATAAAAGATCAATTAAACCATTTTCTGGTATACAAGATATTCTGTCAGAAAGTGTAACTCCAGAAGATATTATGGAAACAGAAAAATTTGACCTTGGCATTGAAGATGATGATGTGAGTGAAGAAAATGTACTTAACACAAAAACAAACATTAGTTCTGAGTCAACTGTATGTAATGCCCTTTCTTTACTTATTTGTGAATATGGGTCTTCTGATGATGATGAGACTACTGTATCAAAGGAAAACATTATTGACAAATGTAACCAAAATTCAGAAACAAATGGAAATCTTCATAAAGTCAACTCAGATCCTAAAAGTGTAGCCATACCTAATTTAAGTGTACCTGAAATGTCAGAACATAAAAGAAAAGATAGTAAAAGCTGTCTTTTGGATGTTGATGATGATGGCCCTGAAGAAATAGCAATATTAAAGAAGGACATAACAGAACTTACTCCGGATATAATACCTGATAAAAAATCAGTTCCTATAGAGAAAAAAGAAAAAATTAAGAGTTACCCTACAAAAGTAATTAAAAAACCACCAAGGTCAAGGGTGCCCTCTACACTTTTACAAAAACTACTTTTTAAGGAAGTGAAACAGGAACGTAATATTATTTTGCAGTGTATAAGACATATAAGAAAAAACAACTATTTTACCAAATAA

Protein

MNPIELSRYIPQSPRMPNYPRFCFPNTQWRFNYGPRVSSWSNQTQSIIDRNEEHWCETCDRGFPNAVILEKHKNQHEKCNIDGCGFVAHPKIITKHIQMQHSTGLYKKIAKLNNPEEIKTWREDRRRNYPTQANIEKKAAMVREKIERGEKMGLSRDKNMCDNKKSGMNRKYKSDNRKFNNKCELNRRKPIEQKFKANQKPSQTPFKKTKVLPVLDDKRSIKPFSGIQDILSESVTPEDIMETEKFDLGIEDDDVSEENVLNTKTNISSESTVCNALSLLICEYGSSDDDETTVSKENIIDKCNQNSETNGNLHKVNSDPKSVAIPNLSVPEMSEHKRKDSKSCLLDVDDDGPEEIAILKKDITELTPDIIPDKKSVPIEKKEKIKSYPTKVIKKPPRSRVPSTLLQKLLFKEVKQERNIILQCIRHIRKNNYFTK

Description

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Subunit

Component of the Mediator complex.

Similarity

Belongs to the Mediator complex subunit 11 family.

Uniprot

A0A1E1W4H4   A0A194PKD0   A0A194RH30   A0A2H1WYU3   A0A2A4JZV5   A0A212FBE5   + More
R4G5S9   A0A0P4VR85   A0A023F739   A0A069DTU4   A0A0V0G964   A0A0M9A6C2   N6U9H6   F7FVR1   A0A1B6I7N0   A0A195EN46   A0A195FLB0   A0A0P5FZ10   H9GBF4   A0A151XJ09   A0A1B6LXI7   A0A0P5TM26   A0A195BUX2   G1NQ33   A0A091NAV6   A0A1B0A1K6   A0A224XT12   A0A1B0BG41   A0A218UR35   H0ZQ01   A0A1A9Y4D8   E1C0G7   U4UET6   G3VGU6   A0A093K0J9   U5EGD0   A0A093GEB7   G3VGU5   A0A139WHE5   H0ZQ00   A0A099ZEU7   A0A091N7P1   A0A091WQ02   U3K0E0   A0A093CHW3   G3VGU7   A0A091Q2K0   A0A1B6IAR8   A0A087VFU5   A0A093QMU5   A0A158NEZ1   A0A094LGT5   V9KRS1   A0A093R011   U3IB96   A0A0Q3TNE8   A0A3Q0G0T2   A0A1U7RG40   A0A093IF33   A0A1U7RQY7   A0A3Q0FXD3   A0A091SYA1   R0KG68   A0A094KF75   A0A1I8PWP2   A0A091UJC4   A0A091HY21   A0A1V4J4N7   A0A091LW71   A0A091TE14   Q28DC6   A0A2I0MRY1   A0A151MHQ3   A0A091LFV9   A0A093NWA1   F7CHS3   A0A099ZYG8   W5MEC7   A0A091UYG2   A0A0N8EJ79   Q0IH05   A0A091NWJ4   W5MEA9   A0A1L8H9D6   W8BPJ1   Q5ZJY2   A0A1L1RSG7   A0A087QXX5  

Pubmed

26354079    22118469    27129103    25474469    26334808    23537049    + More
17495919    21881562    20838655    20360741    15592404    21709235    18362917    19820115    21347285    24402279    23749191    23371554    22293439    20431018    27762356    24495485    15642098   

EMBL

GDQN01009202    JAT81852.1    KQ459601    KPI93782.1    KQ460207    KPJ16630.1    + More
ODYU01012043    SOQ58136.1    NWSH01000331    PCG77339.1    AGBW02009346    OWR51050.1    GAHY01000260    JAA77250.1    GDKW01002220    JAI54375.1    GBBI01001659    JAC17053.1    GBGD01001698    JAC87191.1    GECL01001516    JAP04608.1    KQ435740    KOX76833.1    APGK01037328    KB740948    ENN77301.1    GECU01024799    JAS82907.1    KQ978625    KYN29591.1    KQ981490    KYN41198.1    GDIQ01253711    JAJ98013.1    AAWZ02026945    KQ982080    KYQ60321.1    GEBQ01011627    JAT28350.1    GDIP01142006    JAL61708.1    KQ976401    KYM92382.1    KL379072    KFP86019.1    GFTR01005325    JAW11101.1    JXJN01013737    MUZQ01000165    OWK56213.1    ABQF01007128    ABQF01007129    ABQF01007130    ABQF01007131    ABQF01007132    ABQF01007133    ABQF01007134    ABQF01007135    ABQF01007136    ABQF01007137    AADN05000383    KB632288    ERL91552.1    AEFK01132493    AEFK01132494    AEFK01132495    AEFK01132496    KL206612    KFV84159.1    GANO01003492    JAB56379.1    KL216222    KFV68575.1    KQ971343    KYB27382.1    KL892096    KGL79493.1    KK843435    KFP85476.1    KK736086    KFR17205.1    AGTO01010658    AGTO01020778    KL460609    KFV12559.1    KK684798    KFQ14130.1    GECU01023756    JAS83950.1    KL491778    KFO11487.1    KL672251    KFW85307.1    ADTU01013485    KL285741    KFZ68597.1    JW868951    AFP01469.1    KL423184    KFW89507.1    ADON01000488    ADON01000489    LMAW01002069    KQK82014.1    KK587885    KFV98201.1    KK491806    KFQ63722.1    KB742389    EOB09112.1    KL349539    KFZ58023.1    KK434286    KFQ89795.1    KL217901    KFP00070.1    LSYS01009367    OPJ67090.1    KK513117    KFP63823.1    KK449125    KFQ72563.1    BC161607    CR855585    AAI61607.1    CAJ81343.1    AKCR02000003    PKK32442.1    AKHW03006155    KYO24013.1    KL323225    KFP55360.1    KL224983    KFW66255.1    AAMC01066456    KL869826    KGL86203.1    AHAT01020396    KL410280    KFQ95477.1    GDIQ01021436    JAN73301.1    BC123380    AAI23381.1    KK642650    KFP96929.1    CM004469    OCT92708.1    GAMC01003460    JAC03096.1    AJ720302    CAG31961.1    KL225995    KFM06079.1   

Proteomes

UP000053268    UP000053240    UP000218220    UP000007151    UP000053105    UP000019118    + More
UP000002280    UP000078492    UP000078541    UP000001646    UP000075809    UP000078540    UP000001645    UP000092445    UP000092460    UP000197619    UP000007754    UP000092443    UP000000539    UP000030742    UP000007648    UP000053584    UP000053875    UP000007266    UP000053641    UP000053605    UP000016665    UP000053258    UP000005205    UP000016666    UP000051836    UP000189705    UP000095300    UP000054308    UP000190648    UP000053872    UP000050525    UP000054081    UP000008143    UP000053858    UP000018468    UP000053283    UP000186698    UP000053286   

Pfam

PF10453   NUFIP1        + More
PF06859   Bin3
PF12171   zf-C2H2_jaz
PF10280   Med11
PF00400   WD40

Interpro

IPR019496   NUFIP1_cons_dom        + More
IPR013087   Znf_C2H2_type       
IPR039772   Bin3-like       
IPR029063   SAM-dependent_MTases       
IPR010675   Bin3_C       
IPR024160   BIN3_SAM-bd_dom       
IPR022755   Znf_C2H2_jaz       
IPR036236   Znf_C2H2_sf       
IPR039136   NUFIP1-like       
IPR019404   Mediator_Med11       
IPR036322   WD40_repeat_dom_sf       
IPR015943   WD40/YVTN_repeat-like_dom_sf       
IPR001680   WD40_repeat       
IPR017986   WD40_repeat_dom       

SUPFAM

SSF53335   SSF53335        + More
SSF57667   SSF57667       
SSF50978   SSF50978       

Gene 3D

2.130.10.10    

ProteinModelPortal

A0A1E1W4H4   A0A194PKD0   A0A194RH30   A0A2H1WYU3   A0A2A4JZV5   A0A212FBE5   + More
R4G5S9   A0A0P4VR85   A0A023F739   A0A069DTU4   A0A0V0G964   A0A0M9A6C2   N6U9H6   F7FVR1   A0A1B6I7N0   A0A195EN46   A0A195FLB0   A0A0P5FZ10   H9GBF4   A0A151XJ09   A0A1B6LXI7   A0A0P5TM26   A0A195BUX2   G1NQ33   A0A091NAV6   A0A1B0A1K6   A0A224XT12   A0A1B0BG41   A0A218UR35   H0ZQ01   A0A1A9Y4D8   E1C0G7   U4UET6   G3VGU6   A0A093K0J9   U5EGD0   A0A093GEB7   G3VGU5   A0A139WHE5   H0ZQ00   A0A099ZEU7   A0A091N7P1   A0A091WQ02   U3K0E0   A0A093CHW3   G3VGU7   A0A091Q2K0   A0A1B6IAR8   A0A087VFU5   A0A093QMU5   A0A158NEZ1   A0A094LGT5   V9KRS1   A0A093R011   U3IB96   A0A0Q3TNE8   A0A3Q0G0T2   A0A1U7RG40   A0A093IF33   A0A1U7RQY7   A0A3Q0FXD3   A0A091SYA1   R0KG68   A0A094KF75   A0A1I8PWP2   A0A091UJC4   A0A091HY21   A0A1V4J4N7   A0A091LW71   A0A091TE14   Q28DC6   A0A2I0MRY1   A0A151MHQ3   A0A091LFV9   A0A093NWA1   F7CHS3   A0A099ZYG8   W5MEC7   A0A091UYG2   A0A0N8EJ79   Q0IH05   A0A091NWJ4   W5MEA9   A0A1L8H9D6   W8BPJ1   Q5ZJY2   A0A1L1RSG7   A0A087QXX5  

KEGG

101744262    K23308 nuclear fragile X mental retardation-interacting protein 1 | (RefSeq) nuclear fragile X menta

GO

GO:0003723   GO:0003676   GO:0008168   GO:0046872   GO:0030515   GO:0000492   GO:0005634   GO:0016363   GO:0005726   GO:0051259   GO:0051117   GO:0022626   GO:0001650   GO:0008023   GO:0045202   GO:0045944   GO:0030674   GO:0070761   GO:0042802   GO:0016592   GO:0006357   GO:0003712   GO:0006914   GO:0005622   GO:0005840   GO:0006412   GO:0005737   GO:0016876   GO:0043039   GO:0004651  

PANTHER

PTHR12315   PTHR13309:SF1  

Subcellular location

Nucleus  

Length:

436

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00644

outside

1  -  436

 

 

Pi

216.972416

Theta

196.55177

Tajima's D

0.854382

CLR

0.458948

CSRT

0.622418879056047

Interpretation

Uncertain