Gene

KWMTBOMO02005

Pre Gene Modal

BGIBMGA013551

Annotation

Mediator_of_RNA_polymerase_II_transcription_subunit_11_[Operophtera_brumata]

Location

Bomo_Chr4(-):9798170-9799012      View in EpiBrowser

Full name

Mediator of RNA polymerase II transcription subunit 11      

Alternative Name

Mediator complex subunit 11
dMED21

Location in the cell

Nuclear   Reliability : 2.167

CDS

ATGGCTGCACCGATGGAAAGGATTCAAGTTCTAGACGAAATAGAAAAGGATATTATCACCTGTCTACAATGTGCAGCTCAAGCACTTCTTGAATTGAGTAAAGAAAAATCTGGTCAAAAACAAGCTGAATCAAACACATCACAGTTTTTAAGAACACTCAGTCAAGTGGAATCAAAGTTGAGTGAACAAATAAATTACTTGACTCAAGTTTCAACTGGACAACCACATGAAGGTTCTGGATATGCTTCACAGAAGGTTTTGCAAATGGCTTGGCATCGTTTAGAACATGTCAGATCATGGGTGAACGAATTGGATCGTCTGAAAGCTTCTCATTTGGCAACTCCAAGAACAGCAACAGGAAGTGTACCAAATGGCAATATGACATCATCTGGCACCAGTACCTGA

Protein

MAAPMERIQVLDEIEKDIITCLQCAAQALLELSKEKSGQKQAESNTSQFLRTLSQVESKLSEQINYLTQVSTGQPHEGSGYASQKVLQMAWHRLEHVRSWVNELDRLKASHLATPRTATGSVPNGNMTSSGTST

Description

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).

Subunit

Component of the Mediator complex.
Component of the Mediator complex, which may include CDK8, MED4, MED6, MED11, MED14, MED17, MED18, MED20, MED21, MED22, MED27, MED28, MED30 and MED31.

Similarity

Belongs to the Mediator complex subunit 11 family.

Keywords

Activator   Complete proteome   Nucleus   Reference proteome   Transcription   Transcription regulation  

Feature

chain  Mediator of RNA polymerase II transcription subunit 11

Uniprot

H9JVI8   A0A0L7L5I7   A0A2A4JZA8   A0A2H1WYI3   A0A194RB95   A0A194PM21   + More
S4PMP7   A0A212FBF1   A0A2J7R479   A0A1B6BYP4   D6WLX0   A0A069DN68   A0A0V0GBH0   A0A023F8F5   A0A067R7U6   R4G3K7   A0A0P4VIS8   A0A1Y1LI96   A0A1W4X6J9   A0A0A9YJH8   A0A0A9YDU9   J3JTF4   E1ZWI2   A0A0T6AUM5   A0A0C9RTA1   A0A195D856   A0A195D180   F4WQP8   A0A195ERL7   A0A158NRV1   A0A151X3E3   A0A154PM30   E9IY73   A0A2A3E1B3   V9IBD8   A0A088AAA4   A0A0N1ITT1   V5GYU9   A0A026WMZ2   A0A1B6MH43   A0A1S3CVY5   A0A0L7RB15   A0A232FEQ2   K7ILU1   E0VF02   A0A2H8TWK5   A0A2S2P4F8   C4WUB7   A0A1B6IIM0   A0A1B6K6Q1   A0A1B6FPJ0   E2BYF9   B4J1T9   B4KY66   B4LFX7   A0A1L8DHX5   A0A1L8DHS1   A0A1W4UPE8   B4PIZ2   Q9VVS4   A0A0K8V6K1   Q2M0D2   B4GRS8   B4QPV8   A0A3B0JLA8   A0A1A9VZX0   A0A034VT91   B4N4E7   A0A1I8PTE5   B3NHP3   A0A1I8MCZ8   A0A0L0BSD2   B3M875   A0A2R7W3S5   U5EVD0   A0A1B0DLG4   T1J453   A0A0K8TRL7   A0A1B0G507   A0A336MQI1   A0A2M4ATK3   A0A1S4HDK1   W8CCM0   A0A182JTI4   T1DNW9   A0A2M3ZJJ8   A0A2M4C375   A0A182PMB6   A0A182WTE0   A0A182V103   A0A182L278   A0A182U9G9   A0A182QCC2   A0A182NE91   A0A0M3QWZ3   A0A182MCK6   A0A182RBS1   A0A182YGZ0   A0A182S830   A0A182W9V0  

Pubmed

19121390    26227816    26354079    23622113    22118469    18362917    + More
19820115    26334808    25474469    24845553    27129103    28004739    25401762    26823975    22516182    23537049    20798317    21719571    21347285    21282665    24508170    30249741    28648823    20075255    20566863    17994087    17550304    10731132    12537572    12537569    12021283    15632085    22936249    25348373    25315136    26108605    26369729    12364791    24495485    20966253    25244985   

EMBL

BABH01038997    JTDY01002792    KOB70717.1    NWSH01000331    PCG77337.1    ODYU01012043    + More
SOQ58133.1    KQ460398    KPJ15098.1    KQ459601    KPI93784.1    GAIX01003445    JAA89115.1    AGBW02009346    OWR51048.1    NEVH01007815    PNF35625.1    GEDC01031148    GEDC01003850    JAS06150.1    JAS33448.1    KQ971343    EFA04179.1    GBGD01003381    JAC85508.1    GECL01000651    JAP05473.1    GBBI01001076    JAC17636.1    KK852820    KDR15580.1    ACPB03005610    GAHY01001591    JAA75919.1    GDKW01001800    JAI54795.1    GEZM01061138    GEZM01061137    JAV70747.1    GBHO01012351    GBRD01004569    GBRD01004568    GDHC01019738    GDHC01003116    JAG31253.1    JAG61252.1    JAP98890.1    JAQ15513.1    GBHO01012352    GDHC01010479    JAG31252.1    JAQ08150.1    APGK01052431    BT126510    KB741212    KB632279    AEE61474.1    ENN72722.1    ERL91278.1    GL434853    EFN74419.1    LJIG01022831    KRT78494.1    GBYB01011960    JAG81727.1    KQ981153    KYN09056.1    KQ977041    KYN06159.1    GL888275    EGI63411.1    KQ981993    KYN30868.1    ADTU01024334    KQ982562    KYQ54957.1    KQ434977    KZC12935.1    GL766908    EFZ14504.1    KZ288460    PBC25487.1    JR037456    AEY57781.1    KQ435752    KOX76194.1    GALX01001414    JAB67052.1    KK107152    QOIP01000007    EZA57016.1    RLU20843.1    GEBQ01004710    JAT35267.1    KQ414617    KOC68033.1    NNAY01000358    OXU28919.1    AAZO01001715    DS235100    EEB11976.1    GFXV01006494    MBW18299.1    GGMR01011762    MBY24381.1    ABLF02040100    AK340997    BAH71487.1    GECU01020940    JAS86766.1    GECU01000833    JAT06874.1    GECZ01017836    GECZ01008315    JAS51933.1    JAS61454.1    GL451478    EFN79243.1    CH916366    EDV98019.1    CH933809    EDW19785.1    CH940647    EDW70376.2    GFDF01008124    JAV05960.1    GFDF01008123    JAV05961.1    CM000159    EDW94583.1    AE014296    AY102649    GDHF01017951    JAI34363.1    CH379069    EAL31002.2    CH479188    EDW40463.1    CM000363    CM002912    EDX10986.1    KMZ00440.1    OUUW01000002    SPP76180.1    GAKP01014216    GAKP01014214    JAC44738.1    CH964095    EDW79021.2    CH954178    EDV51838.1    JRES01001431    KNC22952.1    CH902618    EDV41014.1    KK854288    PTY14229.1    GANO01001931    JAB57940.1    AJVK01016427    JH431837    GDAI01000817    JAI16786.1    CCAG010023642    UFQT01002158    SSX32814.1    GGFK01010814    MBW44135.1    AAAB01008964    GAMC01003461    JAC03095.1    GAMD01002490    JAA99100.1    GGFM01007953    MBW28704.1    GGFJ01010584    MBW59725.1    AXCN02000864    CP012525    ALC44421.1    ALC45033.1    AXCM01000972   

Proteomes

UP000005204    UP000037510    UP000218220    UP000053240    UP000053268    UP000007151    + More
UP000235965    UP000007266    UP000027135    UP000015103    UP000192223    UP000019118    UP000030742    UP000000311    UP000078492    UP000078542    UP000007755    UP000078541    UP000005205    UP000075809    UP000076502    UP000242457    UP000005203    UP000053105    UP000053097    UP000279307    UP000079169    UP000053825    UP000215335    UP000002358    UP000009046    UP000007819    UP000008237    UP000001070    UP000009192    UP000008792    UP000192221    UP000002282    UP000000803    UP000001819    UP000008744    UP000000304    UP000268350    UP000091820    UP000007798    UP000095300    UP000008711    UP000095301    UP000037069    UP000007801    UP000092462    UP000092444    UP000075881    UP000075885    UP000076407    UP000075903    UP000075882    UP000075902    UP000075886    UP000075884    UP000092553    UP000075883    UP000075900    UP000076408    UP000075901    UP000075920   

PRIDE

H9JVI8    Q9VVS4   

Pfam

PF10280   Med11

Interpro

IPR019404   Mediator_Med11       

ProteinModelPortal

H9JVI8   A0A0L7L5I7   A0A2A4JZA8   A0A2H1WYI3   A0A194RB95   A0A194PM21   + More
S4PMP7   A0A212FBF1   A0A2J7R479   A0A1B6BYP4   D6WLX0   A0A069DN68   A0A0V0GBH0   A0A023F8F5   A0A067R7U6   R4G3K7   A0A0P4VIS8   A0A1Y1LI96   A0A1W4X6J9   A0A0A9YJH8   A0A0A9YDU9   J3JTF4   E1ZWI2   A0A0T6AUM5   A0A0C9RTA1   A0A195D856   A0A195D180   F4WQP8   A0A195ERL7   A0A158NRV1   A0A151X3E3   A0A154PM30   E9IY73   A0A2A3E1B3   V9IBD8   A0A088AAA4   A0A0N1ITT1   V5GYU9   A0A026WMZ2   A0A1B6MH43   A0A1S3CVY5   A0A0L7RB15   A0A232FEQ2   K7ILU1   E0VF02   A0A2H8TWK5   A0A2S2P4F8   C4WUB7   A0A1B6IIM0   A0A1B6K6Q1   A0A1B6FPJ0   E2BYF9   B4J1T9   B4KY66   B4LFX7   A0A1L8DHX5   A0A1L8DHS1   A0A1W4UPE8   B4PIZ2   Q9VVS4   A0A0K8V6K1   Q2M0D2   B4GRS8   B4QPV8   A0A3B0JLA8   A0A1A9VZX0   A0A034VT91   B4N4E7   A0A1I8PTE5   B3NHP3   A0A1I8MCZ8   A0A0L0BSD2   B3M875   A0A2R7W3S5   U5EVD0   A0A1B0DLG4   T1J453   A0A0K8TRL7   A0A1B0G507   A0A336MQI1   A0A2M4ATK3   A0A1S4HDK1   W8CCM0   A0A182JTI4   T1DNW9   A0A2M3ZJJ8   A0A2M4C375   A0A182PMB6   A0A182WTE0   A0A182V103   A0A182L278   A0A182U9G9   A0A182QCC2   A0A182NE91   A0A0M3QWZ3   A0A182MCK6   A0A182RBS1   A0A182YGZ0   A0A182S830   A0A182W9V0  

KEGG

101742738    K15131 mediator of RNA polymerase II transcription subunit 11 | (RefSeq) mediator of RNA polymerase

GO

GO:0003712   GO:0006357   GO:0016592   GO:0006366   GO:0007406   GO:0003713   GO:0005634   GO:0019432   GO:0043565   GO:0005737   GO:0016876   GO:0043039   GO:0004651  

Subcellular location

Nucleus  

Length:

134

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0

Exp number, first 60 AAs:

0

Total prob of N-in:

0.21052

outside

1  -  134

 

 

Pi

259.703672

Theta

203.403063

Tajima's D

0.807748

CLR

0.047637

CSRT

0.603919804009799

Interpretation

Uncertain