Gene

KWMTBOMO01997  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA013565

Annotation

PREDICTED:_CD109_antigen-like_[Amyelois_transitella]

Location

Bomo_Chr4(+):9651363-9673427      View in EpiBrowser

Location in the cell

PlasmaMembrane   Reliability : 2.409

CDS

ATGATTGAAAAAATCAAGACTCTACTCCTGTTCATTTTAAGCGTGCCAGCTGTAACGCAATGTATATCGGTTGTGGGGCCACAAATATTGCGACCATTTAGTTCATACAGTGTTGCTATAGCGGGAGGCTCCCGGGCATACACGCTGTATGTGGCAGTAGAAGGAAGACGAGAGAATGGGGAACAGTTCTCACAAGGTCGCGAGGTACAAATACCCGCAGCATCCGCAAGGCTAATAGAGCTTGAAATCGGAGACCCGGGGCCGGGTCGGTACTCGCTGGTTGCGCGGTCTACCTCAGGACCGCTATTCTCTTCCTCCGCGCCACTGACCTACCAACCGAGAAGTTTCTGCGTCTTTATACAGACAGACAAACGAATCTACCAGCCCGGCGACACCATTAACTTTAGGACTATCGCTTTGGACAAATACCTATTACCACTTTCCGGCACTGCGGATATAAGTATACTGGATGCCGGTGGTTCGTCTATAAGAGAATGGGCCGGTCTTACTATAGATCGAGGGATTATAAGCGAAGAGCTCATATTAGCTGATGAACCTACTCTAGGAGAATGGAAGATACAGGTAGAAGTACGTGGGCAGAAATATTCGAAAAATGTACTGGTGGCGGACTACGTGCTGCCGAAGTTTAATATGGAAATGAACATACCCAAGGAGGTGCTCTTCAGCGATGGAAGGTTCAATATCAACGTTACTGCTAAACATTTCAACGGACTACCAGTCCGCGGTGAGGTAACGTTCTCTGCATATGCTGTATTTTTCTCTGGCCTCCTGCAACCAGTAGTTGGTTCACCAGCTAGAAAGGTAGCTGATATAAACGGACAAGTAGAAGTGACCTACGACCTCAAAACGGACCTTGATCTCGCAGAAGACGCAGCGAGGCCACTTGTAGTAGAAGCTATCTTAGAAGAAAAAGATACGTTGATAAAACAGAACATATCCTCAAGAATTCTACTGCTTAGAACTCCTTACAGACTGAAAGTTACGGCTCCGGAGTATTTCAAGCCCACACTGCCTTATATTGTTCAGATTGAAGTGGTAGATACTTCGGGACATGCAATGGAGATAAACGATGAAGTAACAGTAGAGAGACTCTGGGACGATGGTGCCCCAGTTAATATTACAACATTGCCGCTTAAGAATGGCCTTGCTACTTACACTTTAATATCCGATGCTGCGCATGTCAATTCTACACTTAATTTGGTGATAAAATACAAGGAGGTCACGGAAAGAGTAGTAAATGTCCAAAGGAATGATTATTCCGGAGGTCAGTTCCTGACTCTCGAAATGCTAACAGCAGCGACGTCACCGGGAGGTGAAATGCGAGCCCGGGTTACTGCCACTGAACCAATGGATATCGTGCATTACGTCGTTATTGGACGAGGAGAAATCCTTCTGGCTAACACTTTAGAATTGAGTCCAGCCCGGCGTAGCGTGGATATCAAGGTGTCGGTAACGCCAGCCATGACGCCGGGGTGTGTGGTGCTCGCCTGGTACCCGCGTCTCGACGCCGCCACCAGCACGGTACTGTCTGCTGCCGTGTATGCTCCTCTGAACAACTTGCTACAACATAAGGTGGCTCTCTCCCCCCTTTCACCGTCTGGAGCGAATCTCAAGCCGAACAGCTTGACAGATTTACGCGTGACCGGAGAGCCCGGATCCCACGTCGCCATACTCGGTGAAGACACAAACGCTGTAGTAGCTGGACTTAGTGGAACGGACGGACGCGGCAACGGACTTGACATGTATACGATCGAACGAGAAGTAGAAAGCTTCAGCGGCCTAAAGCATTCAGTATTTAAAAACGAAGACCACCTTCCCGGAATGGGTATAGATTTAGGAGGATACACGGCATCGGACGTATTCAAAAACTCCGGACTTGTGATCTTAACCGACGGCGTTATTGTGCAAAATATCGACGATAATATACCATCGGATTCTAATGTAGAGACTGGTACGAGGGCTCCACTAGCGGGACCGTACGCTTTCAGCCGCCTCCCCCCTCCCCCCTCCCCGCGGTACTACCTCACCGTCACACCGCAACCCACTTGGGCAGCCACCAACTTTACTATTGGTAATGATGGACAAGGCACGAAAGAGCGCTGGACTCCAACATCGCCAGGAGAATATGTGGTAGGAGCGTTCGCCGTTCATCCCACCCTAGGACTGGGGGTTGCCGAACCACAGAGATTCACCACGTCCGTTCCGTTATCCATTACCGCGGAGCTCCCTGCAAGCTTACAGAAAGGAGAAACAGTGGCCGCAGTCGTCATACTGAAAACGTCACTGGCCGTGGACACTTCCGTTGAAGTCACTTTCTACAACAGCGACCAATACTTCGAATTCGAGCCTTTGGACAACGACGTCGACTCTGCGAAAAAGATCGAGTTGTTCCGTCGCGAGCGGGTGACGGTGCCGGCGCGCGGCTCGGTGAGCACCGCCTTCCTTGTACGCGCCGTCCGCATCGGGGACGCTCCCATCATCGTCGAGGCCACCGGGAACGGGGTCTCGGACTCGCTCTTCAGGACCATCCATGTTAAAGATGGATACGAAGAGGAGGTGTGGAAGTGGAGTCTGATCGACGCGCGGCGCGGCGTGGGTCGTGCGAATATATCGCTGGAGGCTGCGGCGGGCGTGCGCGTTAGCAGTGTGTCGCTGCAGACGGCTGGCGACATGTTGGCGAGCGCGTTACACGCCGCGCGCACGCCGCCGTCGCCCGCCGCCGACCCGCCACAAGCGGCGCGTCCTCTCGCGCTCGCGTGCGTGTTACTCGACTATCTACAGGCTACTGGGCAGGAAGAACCAGGACTTATACAAGAAATGCGAGCTCTAGCATCAATTGGATACCAGCGTTTGATGGCGTATCGTCGAGCCGATGGATCATTTGCATCAGAAACCGATAGCGAGGCCGTAGGTGACCCGTGGATGACAGCTGTGTCATTACGGTGGTTGTCTCGGTGCGGGAAGTACGTGGAGGCATCAAGCAGCGCAAGCGCGGGCGCGGCTCGGTGGCTGGCGGCCGCGCAGGAACAGGACGGCTCCTGGACTACACCCACCTCTACACCTAACGACCCTCGGGCACAGACCACCCTGCCACTCACTGCACACGCACTACTCGCTCTACAGCAAACGAAGGGCAGCGATAGTTTGTTTAAAAACAACATTAATAAAGCTGTGGACTACGTGGCGCGCGGGCTGACGGCGTCGCTGGACGCGTACTCACTGGCGGTGTCGGGCGCGGCGCTCGCTGCGGCGCGACATCAACACGCCACGCTCGCGCTACAGATCATGGACAAATACACCAACACTACTGGCGGCTCGCTGTACTGGAGTCGTGGGGTGTCAGGGTCTGAATGGCGCAACCCCTGGCTGCGATACAATAGCTTGGCGCTGACGACAGCCGCGTGGGGTCTCCGCTGTATGCTAGCTGCACGACTACTGGACGAATCCATACCGGTCGTCAACTACCTACTGCAGTATTCCCCAAGCGATCCTGATCCTGACGTTGTGGACGCTTTAGCTCAGTTTGCTGAAACAATACGATCATCTTCGAAACTGCGGATCTCAGTAAATGTGACGGGTTCAGAAGAGACCAGACAGTTCCAGATTGGTGAAAATAACGCGCTCATCATACAGACACAATCGATCCGCGGCAGTAGTGCGGCGACAGCGAGCGCCAGTGCGGTGTCGGAAGGTCGTGGAGTCGCGGTGGTAGGACTGCGCGGCATCGGCGTGTCGCGGGCGACAGCTGCGTGGCCGCGCTACACGCTCGACCCGCGGCGTGACATGCGCTCCACGCCGTACCGGCTCCAACTCTCCATCTGCTATGGGTTCGTCGCTCAGAGTAACGACACAAAAAGCGGATTTGTGTTGATGACCGTACAACTTCCATCCGGATATTTAGCCGATATAAACACAATTTCTGAACTAACGTCAGCGTCACAAGTAGTGCGTGCACGTGTAACGGCGGGGGGTGCGCGGGTGGTGGGGTGGGTGCGAGCGACACGTGCGGAGACCTGCGCCACGCTGTCAGCACCGCGAGCTCTGCCCGTCGCACACCAGCGCCCCGCCTGGGTTACACTCACCGACCTCTATGACTCCAGTCATCGCGCCCGTGTGTTCTACGAGGCGGTTCCGAGTTCGTCGTGTGACGTATGTAGCGCGTGGCCGTCGTGCAGCCGCGCGTGCGGTGCCGCCGCCTCGCAGCGAGCCGACCCGCCCCGCGACCCGCTCCGCAACCCCTCGCAACCAGACTCCGCGCTCCTGCTCGCGCCACAACTAGTTGCCATACTCGCTACTGCTCTGCTTACCATATTAATACATCTGTGA

Protein

MIEKIKTLLLFILSVPAVTQCISVVGPQILRPFSSYSVAIAGGSRAYTLYVAVEGRRENGEQFSQGREVQIPAASARLIELEIGDPGPGRYSLVARSTSGPLFSSSAPLTYQPRSFCVFIQTDKRIYQPGDTINFRTIALDKYLLPLSGTADISILDAGGSSIREWAGLTIDRGIISEELILADEPTLGEWKIQVEVRGQKYSKNVLVADYVLPKFNMEMNIPKEVLFSDGRFNINVTAKHFNGLPVRGEVTFSAYAVFFSGLLQPVVGSPARKVADINGQVEVTYDLKTDLDLAEDAARPLVVEAILEEKDTLIKQNISSRILLLRTPYRLKVTAPEYFKPTLPYIVQIEVVDTSGHAMEINDEVTVERLWDDGAPVNITTLPLKNGLATYTLISDAAHVNSTLNLVIKYKEVTERVVNVQRNDYSGGQFLTLEMLTAATSPGGEMRARVTATEPMDIVHYVVIGRGEILLANTLELSPARRSVDIKVSVTPAMTPGCVVLAWYPRLDAATSTVLSAAVYAPLNNLLQHKVALSPLSPSGANLKPNSLTDLRVTGEPGSHVAILGEDTNAVVAGLSGTDGRGNGLDMYTIEREVESFSGLKHSVFKNEDHLPGMGIDLGGYTASDVFKNSGLVILTDGVIVQNIDDNIPSDSNVETGTRAPLAGPYAFSRLPPPPSPRYYLTVTPQPTWAATNFTIGNDGQGTKERWTPTSPGEYVVGAFAVHPTLGLGVAEPQRFTTSVPLSITAELPASLQKGETVAAVVILKTSLAVDTSVEVTFYNSDQYFEFEPLDNDVDSAKKIELFRRERVTVPARGSVSTAFLVRAVRIGDAPIIVEATGNGVSDSLFRTIHVKDGYEEEVWKWSLIDARRGVGRANISLEAAAGVRVSSVSLQTAGDMLASALHAARTPPSPAADPPQAARPLALACVLLDYLQATGQEEPGLIQEMRALASIGYQRLMAYRRADGSFASETDSEAVGDPWMTAVSLRWLSRCGKYVEASSSASAGAARWLAAAQEQDGSWTTPTSTPNDPRAQTTLPLTAHALLALQQTKGSDSLFKNNINKAVDYVARGLTASLDAYSLAVSGAALAAARHQHATLALQIMDKYTNTTGGSLYWSRGVSGSEWRNPWLRYNSLALTTAAWGLRCMLAARLLDESIPVVNYLLQYSPSDPDPDVVDALAQFAETIRSSSKLRISVNVTGSEETRQFQIGENNALIIQTQSIRGSSAATASASAVSEGRGVAVVGLRGIGVSRATAAWPRYTLDPRRDMRSTPYRLQLSICYGFVAQSNDTKSGFVLMTVQLPSGYLADINTISELTSASQVVRARVTAGGARVVGWVRATRAETCATLSAPRALPVAHQRPAWVTLTDLYDSSHRARVFYEAVPSSSCDVCSAWPSCSRACGAAASQRADPPRDPLRNPSQPDSALLLAPQLVAILATALLTILIHL

Uniprot

A0A2A4K0R1   A0A2H1W715   A0A212ESZ1   A0A194PK28   A0A2J7QEV3   A0A2J7QEX5   + More
D6WNG7   K7IPL4   A0A2J7QEW9   A0A0L7R3H8   A0A026W8T4   A0A2H8TEP0   W4VRL8   F4W4T0   N6TEB4   A0A1W4XVV5   A0A1W4XKQ3   A0A069DYD0   A0A195F188   X1WIX6   A0A195CTH6   A0A1Y1N0P3   A0A1Y1MXT8   A0A182VF74   E2BBY3   T1HQX7   A0A067R7H5   A0A0P5Y025   A0A0P6FCX3   Q16YC2   A0A226E3R3   A0A182W6G9   Q7Q4E8   A0A084W5W6   A0A1J1IHW0   A0A1Q3FP57   A0A151XGB6   A0A1S4FJW9   A0A0P5C329   B0W4H8   A0A0P5Q9T6   A0A0P5JA21   A0A0P5JGX1   A0A0P5ER46   A0A0P5P270   A0A2M4B9C0   A0A0P5GMZ6   A0A0P5J991   A0A0P5C304   A0A0P4WZC1   A0A2M4B954   A0A0P5H7P0   A0A0P6AXC5   A0A0P6HW98   A0A0P6GIN4   A0A0P6DP15   A0A0P5P8K8   A0A0P5YX21   A0A1Q3FPG7   A0A2M4CU01   A0A1S4J4I6   A0A1S4J5W0   A0A1S4J4I1   A0A2M4A1M9   A0A0P4XMI4   A0A0P6EUY0   A0A2M4A166   A0A2M4A102   A0A1S4J5E3   A0A0P6F7M0   B4KF57   A0A1S4J5F1   A0A1S4J428   A0A1S4J5E6   A0A1Q3FPC5   A0A1S4J433   A0A1S4J426   A0A0N8AH08   A0A0P5PVL2   A0A0P4XLA2   B4LTZ3   A0A0P5H0X8   A0A034V322   A0A3B0JBD4   B3MJF0   A0A0M4EBS6   A0A0L0BS95   B4G8D4   W8APZ6   A0A0K8U033   E2ACP6   Q29N17   E9G461   A0A151JAI5   A0A0P5G5P4   B4MU18   B4JDV4  

Pubmed

22118469    26354079    18362917    19820115    20075255    24508170    + More
21719571    23537049    26334808    28004739    20798317    24845553    17510324    12364791    14747013    17210077    24438588    17994087    25348373    26108605    24495485    15632085    21292972   

EMBL

NWSH01000331    PCG77353.1    ODYU01006619    SOQ48622.1    AGBW02012699    OWR44597.1    + More
KQ459601    KPI93791.1    NEVH01015305    PNF27124.1    PNF27125.1    KQ971343    EFA04694.1    PNF27126.1    KQ414663    KOC65374.1    KK107356    EZA52046.1    GFXV01000761    MBW12566.1    GANO01001585    JAB58286.1    GL887553    EGI70799.1    APGK01032729    APGK01032730    APGK01032731    KB740848    ENN78704.1    GBGD01000097    JAC88792.1    KQ981880    KYN33932.1    ABLF02038594    ABLF02038604    ABLF02051825    KQ977304    KYN03797.1    GEZM01017816    JAV90440.1    GEZM01017817    JAV90439.1    GL447175    EFN86807.1    ACPB03004741    ACPB03004742    ACPB03004743    KK852655    KDR19308.1    GDIP01066625    JAM37090.1    GDIQ01051845    JAN42892.1    CH477519    EAT39604.1    LNIX01000007    OXA51607.1    AAAB01008964    EAA12171.3    ATLV01020702    KE525305    KFB45610.1    CVRI01000054    CRK99837.1    GFDL01005666    JAV29379.1    KQ982174    KYQ59338.1    GDIP01176262    JAJ47140.1    DS231837    EDS33561.1    GDIQ01138759    JAL12967.1    GDIQ01206482    GDIQ01204639    GDIQ01202839    GDIQ01099423    JAK48886.1    GDIQ01249675    GDIQ01247876    GDIQ01243432    GDIQ01243431    GDIQ01206481    GDIQ01206480    GDIQ01204637    GDIQ01204636    GDIQ01202837    GDIQ01196345    GDIQ01148653    GDIQ01096423    GDIQ01068932    JAK48888.1    GDIQ01269079    JAJ82645.1    GDIQ01136207    JAL15519.1    GGFJ01000461    MBW49602.1    GDIQ01239380    JAK12345.1    GDIQ01202838    JAK48887.1    GDIP01176263    JAJ47139.1    GDIP01252804    JAI70597.1    GGFJ01000443    MBW49584.1    GDIQ01231226    JAK20499.1    GDIP01023005    JAM80710.1    GDIQ01028909    JAN65828.1    GDIQ01032702    JAN62035.1    GDIQ01074781    JAN19956.1    GDIQ01132125    JAL19601.1    GDIP01052080    JAM51635.1    GFDL01005667    JAV29378.1    GGFL01004622    MBW68800.1    GGFK01001334    MBW34655.1    GDIP01239707    JAI83694.1    GDIQ01070531    JAN24206.1    GGFK01001164    MBW34485.1    GGFK01001175    MBW34496.1    GDIQ01053487    JAN41250.1    CH933807    EDW13040.2    GFDL01005719    JAV29326.1    GDIP01148273    JAJ75129.1    GDIQ01125117    JAL26609.1    GDIP01239706    JAI83695.1    CH940649    EDW65046.2    GDIQ01233033    JAK18692.1    GAKP01022410    JAC36542.1    OUUW01000004    SPP79664.1    CH902620    EDV31360.2    CP012523    ALC40101.1    JRES01001441    KNC22907.1    CH479180    EDW28614.1    GAMC01018446    GAMC01018443    JAB88112.1    GDHF01032242    JAI20072.1    GL438568    EFN68790.1    CH379060    EAL33526.3    GL732531    EFX86067.1    KQ979262    KYN22068.1    GDIQ01245925    JAK05800.1    CH963852    EDW75607.2    CH916368    EDW03474.1   

Proteomes

UP000218220    UP000007151    UP000053268    UP000235965    UP000007266    UP000002358    + More
UP000053825    UP000053097    UP000007755    UP000019118    UP000192223    UP000078541    UP000007819    UP000078542    UP000075903    UP000008237    UP000015103    UP000027135    UP000008820    UP000198287    UP000075920    UP000007062    UP000030765    UP000183832    UP000075809    UP000002320    UP000009192    UP000008792    UP000268350    UP000007801    UP000092553    UP000037069    UP000008744    UP000000311    UP000001819    UP000000305    UP000078492    UP000007798    UP000001070   

Pfam

PF07678   TED_complement        + More
PF17791   MG3
PF01835   MG2
PF00207   A2M
PF07677   A2M_recep
PF07703   A2M_BRD
PF17789   MG4

Interpro

IPR011626   Alpha-macroglobulin_TED        + More
IPR036595   A-macroglobulin_rcpt-bd_sf       
IPR008930   Terpenoid_cyclase/PrenylTrfase       
IPR041555   MG3       
IPR002890   MG2       
IPR013783   Ig-like_fold       
IPR011625   A2M_N_BRD       
IPR001599   Macroglobln_a2       
IPR009048   A-macroglobulin_rcpt-bd       
IPR040839   MG4       
IPR019742   MacrogloblnA2_CS       
IPR041813   A2M_TED       
IPR014756   Ig_E-set       

SUPFAM

SSF48239   SSF48239        + More
SSF49410   SSF49410       
SSF81296   SSF81296       

Gene 3D

2.60.40.10     2.60.40.690    

CDD

cd02897  A2M_2

ProteinModelPortal

A0A2A4K0R1   A0A2H1W715   A0A212ESZ1   A0A194PK28   A0A2J7QEV3   A0A2J7QEX5   + More
D6WNG7   K7IPL4   A0A2J7QEW9   A0A0L7R3H8   A0A026W8T4   A0A2H8TEP0   W4VRL8   F4W4T0   N6TEB4   A0A1W4XVV5   A0A1W4XKQ3   A0A069DYD0   A0A195F188   X1WIX6   A0A195CTH6   A0A1Y1N0P3   A0A1Y1MXT8   A0A182VF74   E2BBY3   T1HQX7   A0A067R7H5   A0A0P5Y025   A0A0P6FCX3   Q16YC2   A0A226E3R3   A0A182W6G9   Q7Q4E8   A0A084W5W6   A0A1J1IHW0   A0A1Q3FP57   A0A151XGB6   A0A1S4FJW9   A0A0P5C329   B0W4H8   A0A0P5Q9T6   A0A0P5JA21   A0A0P5JGX1   A0A0P5ER46   A0A0P5P270   A0A2M4B9C0   A0A0P5GMZ6   A0A0P5J991   A0A0P5C304   A0A0P4WZC1   A0A2M4B954   A0A0P5H7P0   A0A0P6AXC5   A0A0P6HW98   A0A0P6GIN4   A0A0P6DP15   A0A0P5P8K8   A0A0P5YX21   A0A1Q3FPG7   A0A2M4CU01   A0A1S4J4I6   A0A1S4J5W0   A0A1S4J4I1   A0A2M4A1M9   A0A0P4XMI4   A0A0P6EUY0   A0A2M4A166   A0A2M4A102   A0A1S4J5E3   A0A0P6F7M0   B4KF57   A0A1S4J5F1   A0A1S4J428   A0A1S4J5E6   A0A1Q3FPC5   A0A1S4J433   A0A1S4J426   A0A0N8AH08   A0A0P5PVL2   A0A0P4XLA2   B4LTZ3   A0A0P5H0X8   A0A034V322   A0A3B0JBD4   B3MJF0   A0A0M4EBS6   A0A0L0BS95   B4G8D4   W8APZ6   A0A0K8U033   E2ACP6   Q29N17   E9G461   A0A151JAI5   A0A0P5G5P4   B4MU18   B4JDV4  

PDB

4LNV     E-value=9.13658e-49,     Score=494

KEGG

101742102    K06530 CD109 antigen | (RefSeq) C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8

GO

GO:0004866   GO:0005615   GO:0016021   GO:0050830   GO:0045087   GO:0005576   GO:0030955   GO:0003824   GO:0005737   GO:0016876   GO:0043039   GO:0004651   GO:0005634  

SignalP

Position:   1 - 21,         Likelihood:  0.910421

 

 

Length:

1448

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

30.1073199999999

Exp number, first 60 AAs:

17.73376

Total prob of N-in:

0.80500

POSSIBLE N-term signal

sequence

inside

1  -  6

TMhelix

7  -  29

outside

30  -  1448

 

 

Pi

243.068124

Theta

180.469738

Tajima's D

1.338882

CLR

0.447017

CSRT

0.747062646867657

Interpretation

Uncertain