Gene

KWMTBOMO01992

Pre Gene Modal

BGIBMGA013559

Annotation

PREDICTED:_pyruvate_kinase-like_[Bombyx_mori]

Location

Bomo_Chr4(-):9456387-9458235      View in EpiBrowser

Full name

Pyruvate kinase      

Location in the cell

Cytoplasmic   Reliability : 2.703

CDS

ATGTCACTACCTTGGCATATTCCATTAGAGGCTGCACCCTGTTTTAAAGAAAAACTCAATGCGGTACAACCAACATTGCTCAAACATTACTGTAACATTAATGTACACGAAAATCCTTGCGAGGAGCTACAAACGGGACTCATGTGTGACATAGGACTTGATAACAGAGAACCAGCTACAATACAAAGACTAATAGCTTCAGGGATGACTGTAGCACGATTAAATATGCAAAATTTAGAACCAGAAGCATGCGCTCAACTTATTCAAAGCATCCGACAAGCTGTGTATAATTATAGTTTAGAGCTAGATTTTGTTTATCCTCTAGCTGTCGTGGTTGATGTCAAAGGTCCAGATATTGTCACAGGAGGACTGAAAAATGGTCCACATGCTACTGTTGAGCTTTTACAAACTGAAACAATTCGGCTAACAATAGATCCCAGTTGGAGGGACTGTGGGACATCGGAATGCCTTTACGTAGGATATGATCAATTGACAGATTTGAATACAGATGATATAATTTATATAGATAGCTTATCACCAGGAAAAATCAAACTAGTTGTTACAGAAGTGGGAGATGATTCCTTAGAATGTCTTATTGTTATTGGCGGTACCATTGGAGCTAGTATGGCAGTGCGTATATCATCAATACCTATGGAAGTACAAAGCTGTAGACGAGATGATAGTGCTGATTCCATTTCCGATATTATTAGTTCAAGCCAAGCATTTGAACATTTAGATGAACAAGTTAATTGGGCTACAGCTTCAGATGTTGATGCTTTATTAGTACCCAACTGCCAAGGATCACATGATATCAAACAAATTAAAGAAATGCTTTCAGAGAAAGGAAAACACATTCTTGTCCTTGCTTGTATAGATACAGTCCTAGGGCTTGATAATATAGATGAAGTACTGGAAGAAGCAGATGGCATTTATGTTGATCGATCTGTTTTGAGTACTGATTTACCAGTAGAAAAAATATTTTTGGCCCAAAAACAGATTCTTGCGAAGTGTAATGCAGTGGGAAAACCTTGCTTATGCAAAGCAGTACTTAATGAACAAATACCAACACTATGCGTAACAGATTTAGCAAATCTCGTTTTAGACGGAGCAGATGTTCTTTCTTTAGAACTTCATTATGATTCACCCCTAAAGAAATTTGCACCATTGTATGACGCTATTCGTATGGCCGAACATTGCTTAGGAGCAGCTGGAGTAATTTGCAGACAAGCAGAAAGAATAACATGGAAACCTAATATTCATGGAAATCAAGATTTACTTAAAAATCGTAACGAGGATCCAACAAAATCTGTTTGTATTACAGCAGCTGAATTGGCAGCATTGTCGCAAGCAGTTGTAATTATATGCTTAACGAATTCAGGTCGTACAGCTAAAATTTTATCCTATATAAAACCGGTGTGTCCTATCGTTGCCGTGACTAGAACTTGTCATACAGCTAGGCAATTGCGATTTTGGCGTGGCGTACGCGCTGTACATTATTTTGAATCTCCTAAAGGAAATTGGTTAAATGAAGTAGAATCCAGGATATTTGCTGCATTAAACTACTGTAAAGCAAAAAGAATGCTACGTGCAGGTGATGCATACGTTATCATTTCTGGATCACGTCGTGGTGTAGGATATTGTGATTCGGTCAAACTTTTATTTGCAAGTGTTCGGGAAGCAACCTATTTGGAATAG

Protein

MSLPWHIPLEAAPCFKEKLNAVQPTLLKHYCNINVHENPCEELQTGLMCDIGLDNREPATIQRLIASGMTVARLNMQNLEPEACAQLIQSIRQAVYNYSLELDFVYPLAVVVDVKGPDIVTGGLKNGPHATVELLQTETIRLTIDPSWRDCGTSECLYVGYDQLTDLNTDDIIYIDSLSPGKIKLVVTEVGDDSLECLIVIGGTIGASMAVRISSIPMEVQSCRRDDSADSISDIISSSQAFEHLDEQVNWATASDVDALLVPNCQGSHDIKQIKEMLSEKGKHILVLACIDTVLGLDNIDEVLEEADGIYVDRSVLSTDLPVEKIFLAQKQILAKCNAVGKPCLCKAVLNEQIPTLCVTDLANLVLDGADVLSLELHYDSPLKKFAPLYDAIRMAEHCLGAAGVICRQAERITWKPNIHGNQDLLKNRNEDPTKSVCITAAELAALSQAVVIICLTNSGRTAKILSYIKPVCPIVAVTRTCHTARQLRFWRGVRAVHYFESPKGNWLNEVESRIFAALNYCKAKRMLRAGDAYVIISGSRRGVGYCDSVKLLFASVREATYLE

Catalytic Activity

ATP + pyruvate = ADP + H(+) + phosphoenolpyruvate

Similarity

Belongs to the pyruvate kinase family.

Uniprot

H9JVJ6   A0A212ESY9   A0A194RCC0   A0A0L7L3J4   A0A2A4J6V0   A0A194PLC6   + More
A0A2H1VS12   A0A0P5T0A6   A0A0P5BE35   A0A0N8DAG1   A0A0P5QRU6   A0A0P5IXU7   J3JXD8   A0A0P4ZYY1   A0A0P4Z8B1   A0A0N8A026   A0A0P5WDT8   A0A2Z5REH9   A0A0P5PF75   A0A0P5EN83   A0A162DCG0   A0A0P5BYV3   A0A0P5TN41   A0A0P4ZTD6   A0A0P5R9S5   A0A0N8D3D1   A0A0P6H8M0   A0A0P5G5H3   A0A2Z5REH8   A0A0P5I6S5   A0A0P5CUB7   A0A0P5RR23   A0A0P5ETT1   A0A0P5PVF5   A0A0P5A0V7   A0A0P5JI55   A0A0P4YPL7   A0A0P5Q9B3   A0A0P5AW78   A0A0P5HLS1   A0A0P5CR60   A0A0P6GNB8   A0A0P4Z602   A0A0P5X7T5   A0A0P5THW1   A0A0P5BM20   A0A0P5WLB5   A0A0N8E2I2   U5ESC2   E9HUQ2   A0A0P6ABY5   A0A0P4WPS4   A0A232ESM8   A0A139WAK3   N6T4X5   A0A182NN15   V5SJ07   A0A1Y1L4F9   K7J236   A0A182VFI7   A0A182LNM2   D6X528   A0A139WAJ1   Q7PPE7   A0A1Y9GJK0   A0A1S4GLJ9   A0A182XDN4   A0A182IDE2   A0A182UE55   A0A182MNQ6   A0A0A9XHK7   A0A1W5YLK4   A0A1X9QDT2   A0A182VPN6   A0A0A9YKR8   V5I8G0   A0A2J7RLW1   A0A182SYI1   A0A0C5QRX0   A0A0A9YVU7   A0A2J7RLY6   A0A1Y9GJY2   A0A182RED7   A0A0K8TLX8   A0A226EGV1   A0A2J7RLV9   A0A084W7S0   A0A2H8TDH4   A0A182PWA9   A0A182JJQ1   J9JR33   A0A2J7RLW3   A0A182KAF7   A0A2I9LPH0   I5ANV2   A0A0R3NNH8   B5DYU6   A0A2L2XYS9   I4DJQ4   A0A1Y1LFI1  

EC Number

2.7.1.40

Pubmed

19121390    22118469    26354079    26227816    22516182    23537049    + More
26760975    21292972    28648823    18362917    19820115    28004739    20075255    20966253    12364791    25401762    26823975    25702953    26369729    24438588    29248469    15632085    17994087    26561354    22651552   

EMBL

BABH01038975    BABH01038976    AGBW02012699    OWR44589.1    KQ460398    KPJ15114.1    + More
JTDY01003243    KOB69891.1    NWSH01002987    PCG67143.1    KQ459601    KPI93798.1    ODYU01004097    SOQ43609.1    GDIP01132793    JAL70921.1    GDIP01185840    JAJ37562.1    GDIP01052959    JAM50756.1    GDIQ01130741    JAL20985.1    GDIQ01207910    JAK43815.1    APGK01052723    APGK01052724    BT127907    KB741213    KB631753    AEE62869.1    ENN72684.1    ERL85807.1    GDIP01219278    JAJ04124.1    GDIP01228677    JAI94724.1    GDIP01195729    JAJ27673.1    GDIP01088202    JAM15513.1    FX983728    BAX07227.1    GDIQ01129439    JAL22287.1    GDIP01145591    JAJ77811.1    LRGB01002864    KZS05735.1    GDIP01182684    JAJ40718.1    GDIP01127394    JAL76320.1    GDIP01221792    JAJ01610.1    GDIQ01103836    JAL47890.1    GDIP01072799    JAM30916.1    GDIQ01023110    JAN71627.1    GDIQ01246938    JAK04787.1    FX983727    BAX07226.1    GDIQ01217946    JAK33779.1    GDIP01165586    JAJ57816.1    GDIQ01115884    JAL35842.1    GDIQ01270260    JAJ81464.1    GDIQ01129438    JAL22288.1    GDIP01209933    JAJ13469.1    GDIQ01198898    JAK52827.1    GDIP01228676    GDIP01201525    GDIP01130092    GDIP01095448    JAI94725.1    GDIQ01126637    JAL25089.1    GDIP01197791    JAJ25611.1    GDIQ01225553    JAK26172.1    GDIP01167933    JAJ55469.1    GDIQ01032763    JAN61974.1    GDIP01221791    JAJ01611.1    GDIP01088201    JAM15514.1    GDIP01126000    JAL77714.1    GDIP01182683    JAJ40719.1    GDIP01084539    JAM19176.1    GDIQ01068212    JAN26525.1    GANO01002423    JAB57448.1    GL732818    EFX64530.1    GDIP01032046    JAM71669.1    GDIP01253375    JAI70026.1    NNAY01002419    OXU21317.1    KQ971382    KYB24935.1    ENN72683.1    KF647624    AHB50486.1    GEZM01068639    JAV66845.1    EEZ97193.2    KYB24934.1    AAAB01008952    EAA10555.6    APCN01005967    AXCM01000245    GBHO01024498    GBHO01023780    GBHO01010803    GBHO01010230    GBHO01006495    GBHO01006493    JAG19106.1    JAG19824.1    JAG32801.1    JAG33374.1    JAG37109.1    JAG37111.1    KX147661    ARI45065.1    KY412773    ARQ20739.1    GBHO01010825    GBHO01010824    GBHO01010805    GBHO01010307    GBHO01010289    GBHO01009918    GDHC01007241    JAG32779.1    JAG32780.1    JAG32799.1    JAG33297.1    JAG33315.1    JAG33686.1    JAQ11388.1    GALX01004750    JAB63716.1    NEVH01002616    PNF41818.1    KM609491    AJQ30115.1    GBHO01023781    GBHO01023776    GBHO01023775    GBHO01010806    GBHO01009950    GBHO01006502    GBHO01006497    JAG19823.1    JAG19828.1    JAG19829.1    JAG32798.1    JAG33654.1    JAG37102.1    JAG37107.1    PNF41819.1    GDAI01002239    JAI15364.1    LNIX01000004    OXA56448.1    PNF41817.1    ATLV01021293    KE525316    KFB46264.1    GFXV01000361    MBW12166.1    ABLF02017366    PNF41820.1    GFWZ01000284    MBW20274.1    CM000070    EIM52637.2    KRT00326.1    EDY68021.1    IAAA01002410    LAA01038.1    AK401522    BAM18144.1    GEZM01057153    JAV72422.1   

Proteomes

UP000005204    UP000007151    UP000053240    UP000037510    UP000218220    UP000053268    + More
UP000019118    UP000030742    UP000076858    UP000000305    UP000215335    UP000007266    UP000075884    UP000002358    UP000075903    UP000075882    UP000007062    UP000075840    UP000076407    UP000075902    UP000075883    UP000075920    UP000235965    UP000075901    UP000075900    UP000198287    UP000030765    UP000075885    UP000075880    UP000007819    UP000075881    UP000001819   

PRIDE

H9JVJ6   

Pfam

PF02887   PK_C        + More
PF00224   PK

Interpro

IPR015793   Pyrv_Knase_brl        + More
IPR001697   Pyr_Knase       
IPR015795   Pyrv_Knase_C       
IPR040442   Pyrv_Kinase-like_dom_sf       
IPR015813   Pyrv/PenolPyrv_Kinase-like_dom       
IPR015806   Pyrv_Knase_insert_dom_sf       
IPR036918   Pyrv_Knase_C_sf       
IPR011037   Pyrv_Knase-like_insert_dom_sf       
IPR018209   Pyrv_Knase_AS       

SUPFAM

SSF52935   SSF52935        + More
SSF51621   SSF51621       
SSF50800   SSF50800       

Gene 3D

2.40.33.10     3.20.20.60     3.40.1380.20    

CDD

cd00288  Pyruvate_Kinase

ProteinModelPortal

H9JVJ6   A0A212ESY9   A0A194RCC0   A0A0L7L3J4   A0A2A4J6V0   A0A194PLC6   + More
A0A2H1VS12   A0A0P5T0A6   A0A0P5BE35   A0A0N8DAG1   A0A0P5QRU6   A0A0P5IXU7   J3JXD8   A0A0P4ZYY1   A0A0P4Z8B1   A0A0N8A026   A0A0P5WDT8   A0A2Z5REH9   A0A0P5PF75   A0A0P5EN83   A0A162DCG0   A0A0P5BYV3   A0A0P5TN41   A0A0P4ZTD6   A0A0P5R9S5   A0A0N8D3D1   A0A0P6H8M0   A0A0P5G5H3   A0A2Z5REH8   A0A0P5I6S5   A0A0P5CUB7   A0A0P5RR23   A0A0P5ETT1   A0A0P5PVF5   A0A0P5A0V7   A0A0P5JI55   A0A0P4YPL7   A0A0P5Q9B3   A0A0P5AW78   A0A0P5HLS1   A0A0P5CR60   A0A0P6GNB8   A0A0P4Z602   A0A0P5X7T5   A0A0P5THW1   A0A0P5BM20   A0A0P5WLB5   A0A0N8E2I2   U5ESC2   E9HUQ2   A0A0P6ABY5   A0A0P4WPS4   A0A232ESM8   A0A139WAK3   N6T4X5   A0A182NN15   V5SJ07   A0A1Y1L4F9   K7J236   A0A182VFI7   A0A182LNM2   D6X528   A0A139WAJ1   Q7PPE7   A0A1Y9GJK0   A0A1S4GLJ9   A0A182XDN4   A0A182IDE2   A0A182UE55   A0A182MNQ6   A0A0A9XHK7   A0A1W5YLK4   A0A1X9QDT2   A0A182VPN6   A0A0A9YKR8   V5I8G0   A0A2J7RLW1   A0A182SYI1   A0A0C5QRX0   A0A0A9YVU7   A0A2J7RLY6   A0A1Y9GJY2   A0A182RED7   A0A0K8TLX8   A0A226EGV1   A0A2J7RLV9   A0A084W7S0   A0A2H8TDH4   A0A182PWA9   A0A182JJQ1   J9JR33   A0A2J7RLW3   A0A182KAF7   A0A2I9LPH0   I5ANV2   A0A0R3NNH8   B5DYU6   A0A2L2XYS9   I4DJQ4   A0A1Y1LFI1  

PDB

6DU6     E-value=4.24301e-70,     Score=674

KEGG

101743678    K00873 pyruvate kinase [EC:2.7.1.40] | (RefSeq) pyruvate kinase-like

PATHWAY

00010    Glycolysis / Gluconeogenesis - Bombyx mori (domestic silkworm)
00230    Purine metabolism - Bombyx mori (domestic silkworm)
00620    Pyruvate metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
01200    Carbon metabolism - Bombyx mori (domestic silkworm)
01230    Biosynthesis of amino acids - Bombyx mori (domestic silkworm)

GO

GO:0016301   GO:0000287   GO:0004743   GO:0030955   GO:0006096   GO:0005737   GO:0032869   GO:0007520   GO:0042593   GO:0009744   GO:0005829   GO:0043186   GO:0007525   GO:0003824   GO:0016876   GO:0043039   GO:0004651   GO:0005634  

PANTHER

PTHR11817  

Length:

564

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0628300000000001

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00029

outside

1  -  564

 

 

Pi

281.696612

Theta

229.520112

Tajima's D

0.603087

CLR

0

CSRT

0.544922753862307

Interpretation

Uncertain