Silkworm Genome Informatics Database

Gene

KWMTBOMO01965

Pre Gene Modal

BGIBMGA005916

Annotation

PREDICTED:_katanin_p80_WD40_repeat-containing_subunit_B1_isoform_X1_[Amyelois_transitella]

Location

Bomo_Chr4(-):8834286-8842811 View in EpiBrowser

Full name

Katanin p80 WD40 repeat-containing subunit B1

Alternative Name

p80 katanin

Location in the cell

Cytoplasmic Reliability : 1.444 Mitochondrial Reliability : 1.507 Nuclear Reliability : 1.251

CDS

ATGGAAGCTACCCGAAGATCATGGAAACTACAAGAATTTGTTGCACACAAAGCAAATGTCAATTGCCTAGCAATGGGACATAAGTCCAATCAGGTTTTAGCAACTGGAGGAGATGACAAAAAAGTAAATTTATGGGCAATTGGAAGACAAAGTTGTTTAATGAGTCTTAGTGGACATACAACCCCTGTAGAATGTGTGTGTTTTGGTCATTCAGAAGACTTAGTATGTGCTGGTTCACAAACTGGTGCCTTAAAAATTTGGGATTTGGAAGCTGCTAAACTGTTAAGAACATTCACAGGGCACAAAGGAGCCATTAAGTGTATGGATTTTCACCCATATGGTGATTATCTAACTACAGGTTCTTGTGACAGTAATGTTAAACTATGGGACACTAGAAAGAGAGGATGTATTGTAACTTATTCTAGTCATAGACTTGCTGTCAATAGCCTGCAGTTTAGTCCCGATGGACAGTGGATTGCATCTGCATGTGAAGATGGTATTGTGAAAGTGTGGGATGTCCGCATAGGTAAAGTACTACAAGAGTTCACTGAACACACTTCAGCTGTGACTTCAGTCAAATTTCATCCACATGAATTCCTGCTTGCAAGTTGCAGCACGGACAGGACAGTAAATTTTTGGGATATGGAAAAATTTCAACTGGTCTCCAAGTTTCAAAAGGATAACACATCTATCAGGCACATGGTATTCAGTGAAGATGGTGGAACTTTGCTTGGGTGTGCTAATGACGGCCTGCATGTGATCGGTTGGGAACCTGCTCGAGTAATGGACACTGTAACTGGACATTGGGGTCAGATTCATGATTTAACAGTGGCTCATACACAATTGATTGCTGCATCATTTCATTCAACATATGTTGTGTTAACAGTTGTGGACTTGAGCAAAGTTCATCCATTTGGTGGACCTCCGCCGGTTTCTCCTCCGATCATTAGAGATCTATCGCCATTTCAAAAAGGACACTCTGTTCGTAAAAGTTTCTCAAAAGAAAAACCACAAAAAGAAGTTTTACATAGACCAACACTTTTAGACGAGAAAACTGCCGAAGAATCAACATCAGGTACAGAAGCTGATGAGGATTCAGGCGCAGTCATATCAAATTTTAATGACTACACTGAAATATTTCGTCCCTCCCGAGCATTGAATAGAACGCCGCCTCCAGCAACAAGTTTATCTTCCGATGATTATTCATTATCAGGACACGAGTCGGTGGAGAAGGATACCGTAGTAAGTGACACGCTTCGTGAGCTGGTACTGAGTGAACCATCACGACCGCTGCCTATACCCTCGCCGCCGCAACGACATCGTACTGAGCATTATTCACGGATACCCACTTCCACTAAAGAACACTATACAGTGATTGAAAAGAAAACTGAGAGCTTTACTAGGGTGATGGACAACACTAAAGAAGAGAAAATGTTTGCTACATCTCCAACATCAACCTTGAGAGATTACACTGCCAATAGTATAACGTCAAGTTCACTCAATAGACATAATTCATACAAAGAAACTAAATCATCTACAGACTTGACCACAAGTAACCTTAGACCCAGTAATAGTGACATGTCGTTGGGCCCGCCATCATTAGGTCCCAGATCGTTATCTTTCACACGAACTTCGAGTGAAACGTCGAGACGCCGGGTTGACAGCGTTCATGATAATGTGACAGTAAACCGAAGTGTAGACGCTGCGGACCGTGAGTCTGAGCCAGAATTTATTCCGTACAACACAGACAGGCCGGTTGGGCTCGACTTAGATGAGTTTTTACCCCGAGGAGTGCGCGAGGGTGGGACCAGACGCGGGCCACGCGGAGTAGTCGTGGAGCCTAGCGAGCAGGAAGTCCTCGGCGTCATGATGCGGGGACACGACTCTATGATGGCCGTGCTCACTGCGAGGCAGAGAGCTTTACAGATATTTCATTCAGTGAGAGTAAATAAGAGTTTAAAAACAGCTTTAGAATCTGTCATTGCTCTGGAAGACACTTCAGTGATCCTGGATATCTTGAATGTCATGGCACATAAACCGTCTCTGTGGAATTTGGATATATGTTTATTAATGTTGCCCAAAATATTTGAACTCCTACAAAGCAAATATGAATCATACATGCAATGTGGTTGTAATGCATTAAGACTCATAGTGCGCAACTTCTCCTCGGTGGTTCGAGCGAATGTGAGTGCTCCTGTGAGAACTCTTGGGGTAGACATACCTCGTGAAGAACGATATTCAAAGTGTATGCAAATACATCGACTCTTGCTTGATGTCCGAGCCTTCTTACTTAAGCGCCAGACACTTCAAGGTAGACTTGGCGCTGCCTTCAGAGACCTTCACACCTTGATGCAACAGGGTTTAGATTGA

Protein

MEATRRSWKLQEFVAHKANVNCLAMGHKSNQVLATGGDDKKVNLWAIGRQSCLMSLSGHTTPVECVCFGHSEDLVCAGSQTGALKIWDLEAAKLLRTFTGHKGAIKCMDFHPYGDYLTTGSCDSNVKLWDTRKRGCIVTYSSHRLAVNSLQFSPDGQWIASACEDGIVKVWDVRIGKVLQEFTEHTSAVTSVKFHPHEFLLASCSTDRTVNFWDMEKFQLVSKFQKDNTSIRHMVFSEDGGTLLGCANDGLHVIGWEPARVMDTVTGHWGQIHDLTVAHTQLIAASFHSTYVVLTVVDLSKVHPFGGPPPVSPPIIRDLSPFQKGHSVRKSFSKEKPQKEVLHRPTLLDEKTAEESTSGTEADEDSGAVISNFNDYTEIFRPSRALNRTPPPATSLSSDDYSLSGHESVEKDTVVSDTLRELVLSEPSRPLPIPSPPQRHRTEHYSRIPTSTKEHYTVIEKKTESFTRVMDNTKEEKMFATSPTSTLRDYTANSITSSSLNRHNSYKETKSSTDLTTSNLRPSNSDMSLGPPSLGPRSLSFTRTSSETSRRRVDSVHDNVTVNRSVDAADRESEPEFIPYNTDRPVGLDLDEFLPRGVREGGTRRGPRGVVVEPSEQEVLGVMMRGHDSMMAVLTARQRALQIFHSVRVNKSLKTALESVIALEDTSVILDILNVMAHKPSLWNLDICLLMLPKIFELLQSKYESYMQCGCNALRLIVRNFSSVVRANVSAPVRTLGVDIPREERYSKCMQIHRLLLDVRAFLLKRQTLQGRLGAAFRDLHTLMQQGLD

Description

Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.

Subunit

Interacts with KATNA1. This interaction enhances the microtubule binding and severing activity of KATNA1 and also targets this activity to the centrosome.

Similarity

Belongs to the WD repeat KATNB1 family.

Uniprot

H9J8S4 A0A2A4JQM0 A0A194PLF5 A0A212FH82 A0A2W1C0Z2 A0A194RCE8 + More
A0A2H1WXF0 A0A1E1WC51 A0A1E1WTR3 A0A067RFG6 A0A1W4WSN4 A0A139WIM1 A0A0P4VQ40 T1ISW5 E0VBT9

Pubmed

19121390 26354079 22118469 28756777 24845553 18362917 + More
19820115 27129103 20566863

EMBL

BABH01041228 BABH01041229 NWSH01000880 PCG73743.1 KQ459601 KPI93828.1 + More
AGBW02008527 OWR53084.1 KZ149895 PZC78780.1 KQ460398 KPJ15144.1 ODYU01011792 SOQ57740.1 GDQN01006496 JAT84558.1 GDQN01000686 JAT90368.1 KK852498 KDR22601.1 KQ971342 KYB27617.1 GDKW01001472 JAI55123.1 JH431448 AAZO01000859 DS235042 EEB10845.1

Proteomes

UP000005204 UP000218220 UP000053268 UP000007151 UP000053240 UP000027135 + More
UP000192223 UP000007266 UP000009046

PRIDE

H9J8S4

Pfam

PF00400 WD40 + More
PF13925 Katanin_con80

Interpro

IPR001680   WD40_repeat        + More
IPR028021   Katanin_C-terminal
IPR017986   WD40_repeat_dom
IPR015943   WD40/YVTN_repeat-like_dom_sf
IPR036322   WD40_repeat_dom_sf
IPR019775   WD40_repeat_CS
IPR020472   G-protein_beta_WD-40_rep
IPR026962   Katanin_bsu1

SUPFAM

SSF50978 SSF50978

Gene 3D

2.130.10.10

ProteinModelPortal

H9J8S4 A0A2A4JQM0 A0A194PLF5 A0A212FH82 A0A2W1C0Z2 A0A194RCE8 + More
A0A2H1WXF0 A0A1E1WC51 A0A1E1WTR3 A0A067RFG6 A0A1W4WSN4 A0A139WIM1 A0A0P4VQ40 T1ISW5 E0VBT9

PDB

5OW5 E-value=3.00354e-34, Score=366

KEGG

101735329 K18643 katanin p80 WD40 repeat-containing subunit B1 | (RefSeq) katanin p80 WD40 repeat-containing s

GO

GO:0008352 GO:0005813 GO:0051013 GO:0007049 GO:0051301 GO:0008017 GO:0005874 GO:0000922 GO:0007019 GO:0016740 GO:0005515 GO:0008168 GO:0005737 GO:0016876 GO:0043039 GO:0004651 GO:0005634

Subcellular location

Cytoplasm   Predominantly cytoplasmic. Localized to the interphase centrosome and mitotic spindle poles.   With evidence from 1 publications.
Cytoskeleton   Predominantly cytoplasmic. Localized to the interphase centrosome and mitotic spindle poles.   With evidence from 1 publications.
Microtubule organizing center   Predominantly cytoplasmic. Localized to the interphase centrosome and mitotic spindle poles.   With evidence from 1 publications.
Centrosome   Predominantly cytoplasmic. Localized to the interphase centrosome and mitotic spindle poles.   With evidence from 1 publications.
Spindle pole   Predominantly cytoplasmic. Localized to the interphase centrosome and mitotic spindle poles.   With evidence from 1 publications.
Spindle   Predominantly cytoplasmic. Localized to the interphase centrosome and mitotic spindle poles.   With evidence from 1 publications.

Length:

789

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0205

Exp number, first 60 AAs:

0.000730000000000001

Total prob of N-in:

0.00091

outside

1 - 789

Pi

26.73503

Theta

218.801814

Tajima's D

0.446731

CLR

1.219818

CSRT

0.494275286235688

Interpretation

Uncertain

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics